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compositionComposition:OXALIPLATIN-100MG
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Prescription Medicine
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OXITAN 100MG INJECTION is used to treat Colon and rectal cancer. It contains Oxaliplatin, which works by killing the cancer cells. Thereby, it helps treat cancer. Sometimes, OXITAN 100MG INJECTION may cause side effects such as mild nausea, vomiting, diarrhoea, fever, and headache. This medicine is known to cause embryo-fetal toxicity. Hence, it is not recommended for use in pregnancy and breastfeeding.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

OXALIPLATIN-100MG

Manufacturer/Marketer :

Dabur India Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About OXITAN 100MG INJECTION

OXITAN 100MG INJECTION is a prescription cancer medication given as an injection into a vein to treat cancer of the colon or rectum. This medicine is designed to target and stop the growth of rapidly dividing cancer cells in the body. It is typically prescribed either after surgery to prevent the cancer from returning, or to manage advanced stages of the disease.

This treatment is given in scheduled cycles, usually once every two weeks, to allow your body time to recover between doses. Since it is given as an intravenous infusion, you do not need to worry about taking it with food, but staying well-hydrated is crucial. Making simple lifestyle adjustments, such as eating small, frequent meals and avoiding cold foods or drinks, can significantly help manage treatment-related side effects.

Many patients experience temporary side effects during treatment, including tiredness, nausea, and a unique sensitivity to cold temperatures. However, you must consult your doctor immediately if you experience serious symptoms such as severe numbness in your hands or feet, difficulty breathing, or signs of an infection like a fever.

Before starting therapy, talk to your doctor if you have a history of kidney disease, nerve disorders, or heart conditions. Do not take this medicine if you have previously had a severe allergic reaction to similar platinum-based chemotherapy drugs.

This medicine can interact with other drugs that affect your kidneys or heart rhythm, as well as alcohol, which can worsen liver stress and dehydration. If you are pregnant, breastfeeding, or planning a pregnancy, consult your doctor immediately, as this medicine can cause harm to a developing baby; elderly patients should also be closely monitored.

Uses of OXITAN 100MG INJECTION

Your doctor may prescribe this medicine to help manage the following conditions:

  • Colorectal Cancer (after surgery): OXITAN 100MG INJECTION is used after surgery to remove a tumor in the colon (stage III colon cancer) to help lower the risk of the cancer returning.
  • Advanced Colorectal Cancer: OXITAN 100MG INJECTION is used to treat colon or rectal cancer that has spread to other parts of the body, helping to shrink tumours and slow down the progression of the disease.

Key Benefits

When used as prescribed, OXITAN 100MG INJECTION offers several important benefits in the treatment of cancer.

  • Reduces the risk of cancer recurrence: After surgery, OXITAN 100MG INJECTION helps destroy microscopic cancer cells that may remain in the body, lowering the risk of the cancer returning.
  • Slows tumour growth: In patients with advanced or metastatic cancer, this medicine helps slow the growth and spread of cancer cells, helping keep the disease under control.
  • Helps shrink tumours: By reducing tumour size in some patients, OXITAN 100MG INJECTION may relieve cancer-related symptoms caused by pressure on surrounding tissues or organs.
  • Supports quality of life: By controlling cancer progression and reducing tumour-related symptoms, this medicine may help improve comfort and enable many patients to maintain their daily activities for longer.
Side effects of Oxitan 100mg Injection 50ml
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • OXITAN 100MG INJECTION will be administered by a nurse or doctor.
  • Do not self-administer.

How OXITAN 100MG INJECTION Works

OXITAN 100MG INJECTION contains oxaliplatin, which works by interfering with the genetic material (DNA) inside cancer cells. It binds to the DNA, creating cross-links that prevent the cells from duplicating their genetic code. Because cancer cells grow and divide much faster than normal cells, they are highly sensitive to this DNA damage. Once the DNA is damaged and cannot replicate, the cancer cells are unable to multiply and eventually die off. This action helps to shrink existing tumours and prevent the disease from spreading further throughout the body.
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Alcohol

Consult your doctor

It is not known if alcohol affects OXITAN 100MG INJECTION. Please consult your doctor.

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Pregnancy

Unsafe

OXITAN 100MG INJECTION may cause foetal harm. Therefore, avoid becoming pregnant during treatment with OXITAN 100MG INJECTION.

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Breast Feeding

Unsafe

Breastfeeding is not recommended during treatment with OXITAN 100MG INJECTION and for three months after the last dose.

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Driving

Caution

OXITAN 100MG INJECTION may cause dizziness or vision problems. Avoid driving or operating machinery if you experience any side effects that might lessen your ability to do so.

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Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before receiving OXITAN 100MG INJECTION.

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Kidney

Caution

OXITAN 100MG INJECTION should not be used if you have severe kidney disease. If you have mild or moderate kidney disease, inform your doctor before receiving OXITAN 100MG INJECTION.

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Children

Unsafe

OXITAN 100MG INJECTION is not recommended for children as safety and effectiveness have not been established.

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Heart

Caution

OXITAN 100MG INJECTION may increase the risk of heart problems. Therefore, please consult your doctor if you have any heart-related problems before using OXITAN 100MG INJECTION.

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Geriatrics

Consult your doctor

Please consult a doctor before administering OXITAN 100MG INJECTION to geriatric patients. Your doctor will prescribe OXITAN 100MG INJECTION if the benefits outweigh the risks.

What if I have taken an overdose of OXITAN 100MG INJECTION

Because this medication is prepared and given by trained medical professionals, an overdose is highly uncommon. If an accidental overdose does occur, the medical staff will monitor you closely and provide immediate supportive care to manage any symptoms.

Diet & Lifestyle Advise

  • Avoid cold foods and drinks: Because this medicine causes temporary, extreme sensitivity to cold, avoid drinking ice-cold liquids, eating cold foods, or inhaling cold air during and immediately after your treatment. Use a straw if you must drink cool liquids, and wear gloves when handling items from the refrigerator.
  • Stay well-hydrated: Drink plenty of room-temperature fluids, such as water or warm broths, to help your kidneys flush the medicine out of your system and prevent dehydration from vomiting or diarrhea.
  • Eat soft, bland foods: To manage nausea or mouth sores, eat small, frequent meals consisting of soft, non-spicy, and non-acidic foods.
  • Protect your skin and stay warm: Wear warm clothing, including socks and gloves, especially in air-conditioned environments or during cold weather, to prevent nerve tingling or muscle spasms.
health query

Have a query?

How Soon It Starts Working

The time required for OXITAN 100MG INJECTION to start to work: The time required for OXITAN 100MG INJECTION to show its action is not clinically established. The time for which the effects of OXITAN 100MG INJECTION last: The duration of action for OXITAN 100MG INJECTION is not clinically established.

What if you forget to take OXITAN 100MG INJECTION

Since this medicine is given in a clinical setting by healthcare professionals, missing a dose is unlikely. However, if you miss a scheduled appointment for your infusion, contact your doctor or clinic immediately to reschedule your treatment.

Storage

•The unopened vials are stored at a controlled room temperature of 20°C to 25°C (68°F to 77°F).
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Inspect the infusion setup: Before the infusion starts, ensure the liquid in the bag is clear and free of particles. If you notice any cloudiness or floating particles, point it out to your nurse immediately.
  • Report infusion site pain: Tell your healthcare provider immediately if you feel pain, burning, redness, or swelling around the injection site during the infusion, as the medicine can damage surrounding tissues if it leaks out of the vein.
  • Avoid cold air and drafts: Wear a scarf over your mouth and nose if you must go outside in cold weather immediately after your infusion to avoid throat spasms.
  • Monitor your temperature: Keep a thermometer at home and check your temperature if you feel unwell; contact your clinic immediately if you develop a fever of 100.4°F (38°C) or higher.
  • Use reliable birth control: Both men and women should use highly effective birth control during treatment and for several months after the final dose to prevent pregnancy.

Drug-Drug Interactions

verifiedApollotooltip
  • Medicines that harm the kidneys: Taking drugs like certain strong antibiotics (aminoglycosides) or water pills (loop diuretics) along with OXITAN 100MG INJECTION may increase the risk of kidney damage.
  • Blood thinners: Combining this medicine with drugs that prevent blood clots, such as warfarin or aspirin, may increase your risk of serious bleeding.
  • Medicines that affect heart rhythm: Medications that prolong the QT interval can increase the risk of dangerous heart rhythms when used alongside OXITAN 100MG INJECTION.
OxaliplatinZiprasidone
Critical
OxaliplatinEscitalopram
Severe

Drug-Drug Interactions

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OxaliplatinZiprasidone
Critical
How does the drug interact with Oxitan 100mg Injection 50ml:
Combining Oxitan 100mg Injection 50ml with Ziprasidone can increase the risk of QTc prolongation.

How to manage the interaction:
Taking Oxitan 100mg Injection 50ml with Ziprasidone is not recommended, please consult your doctor before taking it.
OxaliplatinEscitalopram
Severe
How does the drug interact with Oxitan 100mg Injection 50ml:
Combining Oxitan 100mg Injection 50ml with Escitalopram can increase the risk of QTc prolongation.

How to manage the interaction:
Although there is a possible interaction between Oxitan 100mg Injection 50ml and Escitalopram, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without talking to your doctor.
OxaliplatinClozapine
Severe
How does the drug interact with Oxitan 100mg Injection 50ml:
Co-administration of Oxitan 100mg Injection 50ml with Clozapine can increase the risk of neutropenia (low white blood count).

How to manage the interaction:
Although taking Oxitan 100mg Injection 50ml and Clozapine together can evidently cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without talking to a doctor.
OxaliplatinTofacitinib
Severe
How does the drug interact with Oxitan 100mg Injection 50ml:
Taking Tofacitinib with Oxitan 100mg Injection 50ml may increase the risk of infection.

How to manage the interaction:
Although taking Oxitan 100mg Injection 50ml and Tofacitinib together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to your doctor.
OxaliplatinChloroquine
Severe
How does the drug interact with Oxitan 100mg Injection 50ml:
Using chloroquine together with Oxitan 100mg Injection 50ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking chloroquine and Oxitan 100mg Injection 50ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
OxaliplatinInfliximab
Severe
How does the drug interact with Oxitan 100mg Injection 50ml:
Combining Infliximab with Oxitan 100mg Injection 50ml can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Oxitan 100mg Injection 50ml with Infliximab can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OxaliplatinSotalol
Severe
How does the drug interact with Oxitan 100mg Injection 50ml:
Using sotalol together with Oxitan 100mg Injection 50ml can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Oxitan 100mg Injection 50ml, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.
OxaliplatinNilotinib
Severe
How does the drug interact with Oxitan 100mg Injection 50ml:
Combining Oxitan 100mg Injection 50ml and nilotinib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Oxitan 100mg Injection 50ml and nilotinib together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
OxaliplatinAmisulpride
Severe
How does the drug interact with Oxitan 100mg Injection 50ml:
Using amisulpride together with Oxitan 100mg Injection 50ml can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Co-administration of Oxitan 100mg Injection 50ml with Amisulpride can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
OxaliplatinDisopyramide
Severe
How does the drug interact with Oxitan 100mg Injection 50ml:
The combined use of Oxitan 100mg Injection 50ml and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Oxitan 100mg Injection 50ml and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with OXITAN 100MG INJECTION when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

OXITAN 100MG INJECTION is used to treat Colon and rectal cancer.
OXITAN 100MG INJECTION works by killing the cancer cells. Thereby, it helps treat cancer.
OXITAN 100MG INJECTION may have an anti-fertility effect, which could be irreversible. Therefore, male patients should seek medical advice on the conservation of sperm prior to treatment with OXITAN 100MG INJECTION.
Avoid drinking or eating anything colder than room temperature. Do not touch any cold objects, wash your hands in cold water, go near air conditioners or freezers, or go outside in cold weather unless absolutely necessary for five days after you receive each dose of OXITAN 100MG INJECTION. Wear a hat, gloves, and a scarf, and cover your mouth and nose if you must go outside in cold weather.
OXITAN 100MG INJECTION may decrease the ability to fight infections due to reduced white blood cells. Stay away from sick people during treatment with OXITAN 100MG INJECTION.
OXITAN 100MG INJECTION is administered to you through an intravenous (IV) infusion. A healthcare professional usually gives it in a clinical setting.
The common side effects of OXITAN 100MG INJECTION are mild nausea, vomiting, diarrhoea, headache, peripheral neuropathy, fatigue, back pain, and stomach pain. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.
This medicine temporarily affects the nerves in your body, particularly when they are exposed to low temperatures. This can cause sudden tingling, numbness, or muscle spasms in your hands, feet, or throat. This sensitivity usually improves a few days after each infusion. Talk to your doctor if this symptom becomes severe or does not go away.
This medicine can cause side effects like dizziness, vision changes, or extreme tiredness, which may affect your ability to drive safely. It is highly recommended to arrange for someone else to drive you home after your appointment. Talk to your doctor or nurse if you have concerns about getting home safely.
Hair thinning or hair loss can occur with this treatment, although it is usually mild compared to other chemotherapy drugs. In most cases, your hair will grow back after the treatment is completed. Talk to your doctor or nurse for tips on managing hair changes.
You should avoid getting "live" vaccines during your treatment, as your immune system will be weakened and you could develop an infection from the vaccine. Always consult your healthcare provider before scheduling any vaccinations. Talk to your doctor to determine which vaccines are safe for you.
A fever can be a sign of a serious infection, which requires immediate medical attention because this medicine lowers your white blood cell count. Contact your healthcare team or go to the nearest emergency room immediately if your temperature rises to 100.4°F (38°C) or higher. Talk to your doctor for guidance on monitoring infections.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.11052 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. U.S. Food and Drug Administration (FDA). 021759S023Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  3. MedlinePlus. A607035 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  4. Oxaliplatin Oxaliplatin. 2011. [Accessed on 22 Jan. 2019]Check here
  5. Oxaliplatin Oxaliplatin. 2002. [Accessed on 26 Mar. 2019]Check here
  6. Oxaliplatin 5mg/ml concentrate for Solution for Infusion - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 02 June 2025]Check here
  7. Oxaliplatin 5mg/ml concentrate for Solution for Infusion - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 02 June 2025]Check here

Country of origin

India

Manufacturer/Marketer address

8/3, Asaf Ali Road, New Delhi-110002
Other Info - OXI0104
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