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  3. Oxramet-G XR 10/1/500 Tablet 7's

Oxramet-G XR 10/1/500 Tablet 7's, Pack of 7 TabletS
Oxramet-G XR 10/1/500 Tablet 7's, Pack of 7 TabletS
Oxramet-G XR 10/1/500 Tablet 7's, Pack of 7 TabletS
Oxramet-G XR 10/1/500 Tablet 7's, Pack of 7 TabletS
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Oxramet-G XR 10/1/500 Tablet is an antidiabetic medicine used to treat Type II Diabetes. It contains Dapagliflozin (sodium-glucose cotransporter-2 inhibitors), Metformin (biguanides), and Glimepiride (sulfonylurea), which work by increasing the amounts of certain natural substances that lower blood sugar when it is high. Common side effects of this medication include vomiting, nausea, abdominal pain, headache, and allergic reactions.

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Composition :

DAPAGLIFLOZIN-10MG + GLIMEPIRIDE-1MG + METFORMIN-500MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Oxramet-G XR 10/1/500 Tablet

Oxramet-G XR 10/1/500 Tablet is an antidiabetic medicine used to treat diabetes. It is used for the treatment of Type II Diabetes. Type II Diabetes Mellitus is a chronic condition that influences the body's metabolism of glucose or blood sugar. Insulin resistance or insufficient insulin production are the two main causes of type 2 diabetes.

Oxramet-G XR 10/1/500 Tablet contains Dapagliflozin (sodium-glucose cotransporter-2 inhibitors), Metformin (biguanides), and Glimepiride (sulfonylurea), which work by increasing the amounts of certain natural substances that lower blood sugar when it is high.

Oxramet-G XR 10/1/500 Tablet may cause certain side effects, such as vomiting, nausea, abdominal pain, headache, and allergic reactions. If these side effects persist or worsen, please consult your doctor. Oxramet-G XR 10/1/500 Tablet should be taken as prescribed by your doctor. 

Oxramet-G XR 10/1/500 Tablet should be avoided if you are allergic to any of the medicines or their components. Inform your doctor about your medical history and the medicines you are taking, including herbs and supplements, before starting the treatment with Oxramet-G XR 10/1/500 Tablet. This can help prevent unwanted effects. Let your doctor know if you are pregnant or breastfeeding before taking Oxramet-G XR 10/1/500 Tablet. It is not recommended for use in children below 18 years of age.

Uses of Oxramet-G XR 10/1/500 Tablet

Oxramet-G XR 10/1/500 Tablet is used in the treatment of Type II Diabetes Mellitus. The detailed uses of Oxramet-G XR 10/1/500 Tablet are as follows:

  • Type 2 diabetes management: Oxramet-G XR 10/1/500 Tablet helps control high blood sugar levels in adults when lifestyle changes and dual therapy are not sufficient.
  • Improved glycemic control: Oxramet-G XR 10/1/500 Tablet regulates blood glucose through several complementary actions, including enhancing insulin secretion, improving how the body responds to insulin, and increasing the elimination of excess glucose through urine.
  • Reduction of HbA1c levels: Oxramet-G XR 10/1/500 Tablet aims to lower glycated hemoglobin (HbA1c), which reflects long-term blood sugar control.
  • Prevention of complications: Oxramet-G XR 10/1/500 Tablet helps reduce the risk of diabetes-related complications such as kidney damage, nerve issues, and heart disease.

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Directions for Use

  • Take Oxramet-G XR 10/1/500 Tablet with food to reduce stomach upset or gastrointestinal side effects.
  • Recommended to take it once daily in the morning or as advised by your doctor.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Oxramet-G XR 10/1/500 Tablet is a combination of three drugs, namely: Dapagliflozin, Metformin and Glimepiride. Oxramet-G XR 10/1/500 Tablet belongs to the group of anti-diabetic medicines used to treat type-2 diabetes mellitus. Dapagliflozin helps remove excess sugar from the body via urine. Metformin helps reduce the sugar production by cells in the liver and delays sugar absorption from the intestines. Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood.

How Oxramet-G XR 10/1/500 Tablet Works

Oxramet-G XR 10/1/500 Tablet contains Dapagliflozin (sodium-glucose cotransporter-2 inhibitors), Metformin (biguanides), and Glimepiride (sulfonylurea), which work by increasing the amounts of certain natural substances that lower blood sugar when it is high.

Storage

• Store in a cool and dry place away from sunlight.• Keep Oxramet-G XR 10/1/500 Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Oxramet-G XR 10/1/500 Tablet
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Oxramet-G XR 10/1/500 Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Oxramet-G XR 10/1/500 Tablet may include low blood sugar, stomach pain and diarrhoea. Seek immediate medical attention if you observe these symptoms or think you might have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Oxramet-G XR 10/1/500 Tablet should be avoided if you are allergic to any of the medicines or their components. Before starting the treatment, inform your doctor about your medical history and the medications you take, including herbs and supplements, to rule out any side effects. It is unknown whether Oxramet-G XR 10/1/500 Tablet can be given to pregnant women or breastfeeding mothers. Hence, inform your doctor if you are pregnant or breastfeeding. It is not recommended for use in children below 18 years of age. Avoid drinking alcohol while on Oxramet-G XR 10/1/500 Tablet as it increases the risk of hypoglycemia and lactic acidosis (when the lactic acid increases in the body, which impacts the functioning of various organs in the body). Inform your doctor if you have any liver/kidney disease, heart problems, and hypertension before taking Oxramet-G XR 10/1/500 Tablet.

Drug-Drug Interactions

verifiedApollotooltip
DapagliflozinGatifloxacin
Critical
MetforminIohexol
Critical

Drug-Drug Interactions

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DapagliflozinGatifloxacin
Critical
How does the drug interact with Oxramet-G XR 10/1/500 Tablet:
Co-administration of Oxramet-G XR 10/1/500 Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Gatifloxacin can be taken with Oxramet-G XR 10/1/500 Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medication without consulting a doctor.
MetforminIohexol
Critical
How does the drug interact with Oxramet-G XR 10/1/500 Tablet:
Co-administration of Iohexol with Oxramet-G XR 10/1/500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Oxramet-G XR 10/1/500 Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIodamide
Critical
How does the drug interact with Oxramet-G XR 10/1/500 Tablet:
Co-administration of Oxramet-G XR 10/1/500 Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Oxramet-G XR 10/1/500 Tablet with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIocarmic acid
Critical
How does the drug interact with Oxramet-G XR 10/1/500 Tablet:
Co-administration of Oxramet-G XR 10/1/500 Tablet and Iocarmic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Oxramet-G XR 10/1/500 Tablet with Iocarmic acid is generally avoided as it can result in an interaction. please consult your doctor before taking it.
MetforminIocetamic acid
Critical
How does the drug interact with Oxramet-G XR 10/1/500 Tablet:
Co-administration of Oxramet-G XR 10/1/500 Tablet and Iocetamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Oxramet-G XR 10/1/500 Tablet with Iocetamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIoxitalamic acid
Critical
How does the drug interact with Oxramet-G XR 10/1/500 Tablet:
Co-administration of Oxramet-G XR 10/1/500 Tablet and Ioxitalamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Oxramet-G XR 10/1/500 Tablet with Ioxitalamic acid is not recommended, please consult your doctor before taking it.
MetforminIoversol
Critical
How does the drug interact with Oxramet-G XR 10/1/500 Tablet:
Co-administration of Ioversol with Oxramet-G XR 10/1/500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Oxramet-G XR 10/1/500 Tablet with Ioversol is not recommended, please consult your doctor before taking it.
MetforminIoglycamic acid
Critical
How does the drug interact with Oxramet-G XR 10/1/500 Tablet:
Co-administration of Ioglycamic acid with Oxramet-G XR 10/1/500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Oxramet-G XR 10/1/500 Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIomeprol
Critical
How does the drug interact with Oxramet-G XR 10/1/500 Tablet:
Co-administration of Iomeprol with Oxramet-G XR 10/1/500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Oxramet-G XR 10/1/500 Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIodixanol
Critical
How does the drug interact with Oxramet-G XR 10/1/500 Tablet:
Co-administration of Iodixanol with Oxramet-G XR 10/1/500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Oxramet-G XR 10/1/500 Tablet with Iodixanol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try doing 30 minutes of moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise weekly. 
  • Include your diet with whole grain foods, fruits and veggies and other fiber-enriched foods. 
  • Add omega-3 fatty acid-containing oils for daily cooking.
  • Avoid taking too much stress as it may elevate your blood sugar level. You can adopt stress management techniques like mindfulness, meditation, or yoga to control stress-related blood sugar changes.
  • Loss of weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Keep your blood pressure as normal (140/90) as possible, as it reduces the risk of cardiovascular diseases in diabetes patients.
  • Avoid smoking and alcohol consumption while on treatment with Oxramet-G XR 10/1/500 Tablet.
  • Take short, frequent meals, and avoid prolonged fasting when taking Oxramet-G XR 10/1/500 Tablet.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Oxramet-G XR 10/1/500 Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

Alcohol increases the impact of metformin on lactate metabolism. Hence, you should not consume excessive amounts of alcohol, either temporarily or permanently, while taking Oxramet-G XR 10/1/500 Tablet.

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Pregnancy

Caution

There are no adequate studies on the effect of Oxramet-G XR 10/1/500 Tablet in pregnancy. If you are pregnant or planning pregnancy, inform your doctor before taking Oxramet-G XR 10/1/500 Tablet.

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Breast Feeding

Caution

Oxramet-G XR 10/1/500 Tablet is generally not recommended in breastfeeding. Hence, if you are breastfeeding, inform your doctor before using Oxramet-G XR 10/1/500 Tablet.

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Driving

Caution

Oxramet-G XR 10/1/500 Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Oxramet-G XR 10/1/500 Tablet may cause lactic acidosis due to metformin accumulation. The risk increases with hepatic insufficiency. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Renal impairment also increases the risk of lactic acidosis. Hence, Oxramet-G XR 10/1/500 Tablet should be used cautiously if you have kidney problems. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Oxramet-G XR 10/1/500 Tablet is not recommended for children below 18 years as the safety and effectiveness were not established.

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Heart

Take Oxramet-G XR 10/1/500 Tablet with caution, especially if you have a history of heart disease. Inform your doctor before receiving the Oxramet-G XR 10/1/500 Tablet if you have a history of heart diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Geriatrics

Caution

Oxramet-G XR 10/1/500 Tablet should be used with caution in elderly patients. Please consult your doctor before use.

FAQs

Oxramet-G XR 10/1/500 Tablet is used for the treatment of Type II Diabetes.

Oxramet-G XR 10/1/500 Tablet contains Dapagliflozin, Metformin, and Glimepiride, which work by increasing the amounts of certain natural substances that lower blood sugar when it is high.

Please consult your doctor if you have concerns and for more information on this.

If you forget to take Oxramet-G XR 10/1/500 Tablet, take it as soon as you remember. However, if it is time for the next dose, avoid taking it and do not double dose to make up for the missed dose. Taking an overdose might cause your sugar level to fall down rapidly.

Country of origin

India

Manufacturer/Marketer address

Plot No 107/108,Namli Block , Ranipool, East Sikkim 737135
Other Info - OXR0029

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 18, 2025 | 11:50 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202293s020lbl.pdf
  2. https://www.drugs.com/metformin.html
  3. https://www.leeford.in/product/3377/dapzigard-10-vdm
  4. https://www.ema.europa.eu/en/medicines/human/EPAR/vildagliptin-metformin-hydrochloride-accord
  5. https://www.addiibiotech.com/products/dartdapa-v

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