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  3. Pacimol MF 250 Suspension 60 ml

Pacimol MF 250 Suspension 60 ml, Pack of 1 ORAL SUSPENSION
Pacimol MF 250 Suspension 60 ml, Pack of 1 ORAL SUSPENSION
Pacimol MF 250 Suspension 60 ml, Pack of 1 ORAL SUSPENSION
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Pacimol MF 250 Suspension is used to treat fever and mild to moderate pain in children. It contains Mefenamic acid and Paracetamol. It works by blocking the action of chemical messengers responsible for making the child feel the sensation of pain, swelling, and other symptoms associated with pain. It reduces a high temperature (fever) by altering the chemical messengers in an area of the brain that regulates body temperature.

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Composition :

MEFENAMIC ACID-100MG + PARACETAMOL-250MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pacimol MF 250 Suspension

Pacimol MF 250 Suspension is used to relieve pain. Pain can be acute (temporary) or chronic (long-lasting). Acute pain is short-term and caused by damage to the tissues of the muscle, bone, or other organs. Chronic pain lasts for a long duration and is caused by pathologies like nerve damage, etc. It helps provide relief from symptoms of muscle pain and dental pain in children. Pacimol MF 250 Suspension is also used to reduce fever.

Pacimol MF 250 Suspension is a combination medicine containing two drugs, namely, Mefenamic acid (NSAID) and Paracetamol (antipyretic). Mefenamic acid works by blocking the effect of a chemical known as prostaglandin, responsible for inducing pain and inflammation in our body. Paracetamol lowers the elevated body temperature and mild pain by inhibiting the synthesis of a chemical messenger (prostaglandin) and promoting heat loss (through sweating) that helps reset the hypothalamic thermostat.

Pacimol MF 250 Suspension may cause certain side effects in your child, such as abdominal pain, cold-like nose symptoms (in children), or diarrhoea (in children). These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your paediatrician. Pacimol MF 250 Suspension should be taken as advised by your doctor. Do not give more than the prescribed dose of Pacimol MF 250 Suspension to the child. Pacimol MF 250 Suspension can be given with or without food. The dose of the medicine will be decided by your paediatrician depending on the type and severity of the infection.

Pacimol MF 250 Suspension is intended for pediatric use only. Avoid giving Pacimol MF 250 Suspension to your child if she/he is allergic to antibiotics. Keep your doctor informed about your child’s health condition, including his current medications and medical history, to rule out any side effects/interactions. Before administration, inform your child’s doctor about liver and kidney disease. Pacimol MF 250 Suspension is not recommended for use in children below six months of age as its safety and efficacy are not established.

Uses of Pacimol MF 250 Suspension

Pacimol MF 250 Suspension is used in the treatment of pain and fever in children. The detailed uses of Pacimol MF 250 Suspension are as follows:

  • Pain Relief: Pacimol MF 250 Suspension is commonly used to alleviate moderate to severe pain, including headaches, dental pain, and muscle aches.
  • Fever Reduction: Pacimol MF 250 Suspension can be effective in lowering fever, making it suitable for treating febrile conditions associated with various infections.
  • Post-Surgical Pain Relief: Pacimol MF 250 Suspension may be used to manage pain following surgical procedures, helping children to recover more comfortably.
  • Treatment of Inflammatory Conditions: Pacimol MF 250 Suspension can be utilised to reduce inflammation and pain associated with conditions like arthritis or other inflammatory disorders.

Directions for Use

  • Pacimol MF 250 Suspension can be given to your child with food to prevent stomach upset.
  • Typically, it is given 2-3 times a day. However, follow the doctor's instructions regarding the required dosage and timing of this medication for optimal effectiveness.
  • Shake the bottle well before each use.
  • Give the prescribed dose to your child by mouth using the measuring cup/dosing syringe/dropper provided with the pack.
  • Avoid using regular household spoons, as they may not measure the dose correctly.

Medicinal Benefits

Pacimol MF 250 Suspension is a combination medicine of Mefenamic acid (an NSAID) and Paracetamol (an antipyretic). Ibuprofen works by blocking the effect of a chemical known as prostaglandin, which is responsible for inducing pain and inflammation in our body. Paracetamol lowers elevated body temperature and mild pain by inhibiting the synthesis of a chemical messenger (prostaglandin) and promoting heat loss (through sweating) that helps reset the hypothalamic thermostat.

How Pacimol MF 250 Suspension Works

Pacimol MF 250 Suspension is a combination medicine containing two drugs, namely, Mefenamic acid (NSAID) and Paracetamol (antipyretic). Mefenamic acid works by blocking the effect of a chemical known as prostaglandin, responsible for inducing pain and inflammation in our body. Paracetamol lowers the elevated body temperature and mild pain by inhibiting the synthesis of a chemical messenger (prostaglandin) and promoting heat loss (through sweating) that helps reset the hypothalamic thermostat.

Storage

• Store in a cool and dry place away from sunlight.• Keep Pacimol MF 250 Suspension out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Pacimol MF 250 Suspension 60 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

What if I have taken an overdose of Pacimol MF 250 Suspension

In case the child accidentally takes an overdose of Pacimol MF 250 Suspension than prescribed and shows some signs of unwanted side effects such as CNS toxicity, especially convulsions, it is necessary to take the patient to an emergency at the nearest medical facility to receive treatment. Timely medical support, helping patients overcome dangerous situations.

Drug Warnings

Avoid giving Pacimol MF 250 Suspension to your child if she or he is allergic to it. Keep your pediatrician informed about your child’s health condition, including their previous medications and medical history, to rule out any side effects or interactions. Before administration, inform the pediatrician about all the OTC medicines, including other vitamin supplements, that your child is taking. It is advised not to give more than the prescribed dose of medicine. Also, inform your doctor if your child has liver or kidney-related issues before administration. Pacimol MF 250 Suspension is intended for use by children. Hence, adults, pregnant women, and breastfeeding mothers should avoid taking this medicine.

Drug-Drug Interactions

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Mefenamic acidMeloxicam
Critical
Mefenamic acidKetorolac
Critical

Drug-Drug Interactions

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Mefenamic acidMeloxicam
Critical
How does the drug interact with Pacimol MF 250 Suspension 60 ml:
Co-administration of Pacimol MF 250 Suspension 60 ml with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Pacimol MF 250 Suspension 60 ml with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
Mefenamic acidKetorolac
Critical
How does the drug interact with Pacimol MF 250 Suspension 60 ml:
Coadministration of Pacimol MF 250 Suspension 60 ml with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Pacimol MF 250 Suspension 60 ml with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidEtodolac
Severe
How does the drug interact with Pacimol MF 250 Suspension 60 ml:
Coadministration of Pacimol MF 250 Suspension 60 ml with Etodolac can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Pacimol MF 250 Suspension 60 ml with Etodolac together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact the doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidLomitapide
Severe
How does the drug interact with Pacimol MF 250 Suspension 60 ml:
Coadministration of Pacimol MF 250 Suspension 60 ml with Lomitapide can cause liver damage.

How to manage the interaction:
Co-administration of Pacimol MF 250 Suspension 60 ml with Lomitapide can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away - fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, bleeding, pain, dark urine, or liver damage. Do not stop using any medications without a doctor's advice.
Mefenamic acidTenofovir disoproxil
Severe
How does the drug interact with Pacimol MF 250 Suspension 60 ml:
Coadministration of Pacimol MF 250 Suspension 60 ml with Tenofovir disoproxil can show additive effect and increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Pacimol MF 250 Suspension 60 ml with Tenofovir Disoproxil together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, red or black tarry stools, vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidWarfarin
Severe
How does the drug interact with Pacimol MF 250 Suspension 60 ml:
Coadministration of Pacimol MF 250 Suspension 60 ml with Warfarin can increase the risk of bleeding.

How to manage the interaction:
Taking Pacimol MF 250 Suspension 60 ml with Warfarin together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
Mefenamic acidPrasugrel
Severe
How does the drug interact with Pacimol MF 250 Suspension 60 ml:
Co-administration of Pacimol MF 250 Suspension 60 ml with Prasugrel can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Pacimol MF 250 Suspension 60 ml with Prasugrel together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidSirolimus
Severe
How does the drug interact with Pacimol MF 250 Suspension 60 ml:
Co-administration of Pacimol MF 250 Suspension 60 ml with Sirolimus can increase the risk or severity of kidney disorders.

How to manage the interaction:
Taking Pacimol MF 250 Suspension 60 ml with Sirolimus together can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidCelecoxib
Severe
How does the drug interact with Pacimol MF 250 Suspension 60 ml:
Coadministration of Pacimol MF 250 Suspension 60 ml with Celecoxib can increase the risk or severity of bleeding and ulcers of the stomach.

How to manage the interaction:
Taking Pacimol MF 250 Suspension 60 ml with Celecoxib together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, loos stools, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidLeflunomide
Severe
How does the drug interact with Pacimol MF 250 Suspension 60 ml:
Coadministration of Pacimol MF 250 Suspension 60 ml with Leflunomide can increase the risk or severity of liver disease.

How to manage the interaction:
Taking Pacimol MF 250 Suspension 60 ml with Leflunomide together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Stress affects the child’s immune system and raises the risk of illness. Hence, try progressive muscle relaxation techniques to relieve stress.
  • Sleeping for 7-9 hours each night can make your child stay fit and safe.
  • Make your child to drink more fluids to avoid dehydration.

Habit Forming

No

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

Pacimol MF 250 Suspension Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Not applicable

-

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Pregnancy

Not applicable

-

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Breast Feeding

Not applicable

-

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Driving

Not applicable

-

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Liver

Caution

Please consult your doctor if your child has a liver impairment or if you have any concerns regarding this.

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Kidney

Caution

Please consult your doctor if your child has a kidney impairment or if you have any concerns regarding this.

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Children

Safe

Pacimol MF 250 Suspension is safe for children above 6 months of age if prescribed by the doctor. Your pediatrician will decide the dose of the medicine. Do not give your child more than the recommended dose.

Have a query?

FAQs

Pacimol MF 250 Suspension is used to treat Pain and Fever.

Mefenamic acid (NSAID) and Paracetamol (antipyretic). Mefenamic acid works by blocking the effect of a chemical known as prostaglandin, which is responsible for inducing pain and inflammation in our body. Paracetamol lowers elevated body temperature and mild pain by inhibiting the synthesis of a chemical messenger (prostaglandin) and promoting heat loss (through sweating).

Pacimol MF 250 Suspension can cause diarrhea as a side effect in some children. If your child has diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your paediatrician tells you to.

The side effects of Pacimol MF 250 Suspension include nausea, indigestion, stomach pain and diarrhoea. If these side effects persist or worsen, please consult your doctor.

Yes, Pacimol MF 250 Suspension is safe to use in prescribed dose and duration. The patient should follow doctor’s recommendations.

Pacimol MF 250 Suspension is generally used for short term and can be stopped when the pain is relieved. However, it should be continued for as long as it is advised by your doctor.

Yes, the use of Pacimol MF 250 Suspension can cause nausea and vomiting. Taking it with food, milk, or antacids can avoid nausea. Avoid giving fried or fatty foods to your child along with Pacimol MF 250 Suspension. If vomiting occurs, let your child drink plenty of water or other fluids by taking small and frequent sips. If vomiting persists and if you notice signs of dehydration such as a low frequency of urination and dark colored and strong-smelling urine, consult your doctor. Do not give any other medicine to your child without consulting your doctor.

Pacimol MF 250 Suspension is contraindicated in patients with known allergy to painkillers (NSAIDS) or any of the components or excipients of this medicine. Also, let the doctor know if the patient has kidney or liver disease.

You are recommended to consult your doctor before giving Pacimol MF 250 Suspension to your child with vitamin B-complex or other supplements.

Yes, the long-term use of Pacimol MF 250 Suspension can cause damage to the kidneys. Normal kidneys produce prostaglandins, a chemical that protects them from damage. Long term use of painkillers lowers the prostaglandins levels in the body leading to kidney damage. Therefore, painkillers are not recommended to patients with underlying kidney disease.

No, taking higher than the recommended dose of Pacimol MF 250 Suspension may increase the risk of side effects such as nausea, vomiting, indigestion, heartburn, diarrhoea and can also harm kidneys when used for extended period of time. If your child pain is not relieved by the recommended doses or if your child experiences increased severity of pain, please consult your doctor.

Store Pacimol MF 250 Suspension below 25°C. Protect from light. Keep it out of reach and sight of children.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra.
Other Info - PAC0175

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 6, 2025 | 9:52 AM IST

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Reference

  1. https://www.centaurpharma.com/downloads/peadiatrics/pyrexia/Centamol%20Plus%20Suspension.pdf
  2. https://www.unibytekids.com/uzimef

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