Paclodep 12.5 Tablet 15's
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About Paclodep 12.5 Tablet 15's
Paclodep 12.5 Tablet 15's belongs to a group of medicines called ‘antidepressants’. It is used in the treatment of depression. Depression is a common mood disorder, which negatively affects a person's daily life described as feelings of sadness, loss, or anger. Depression symptoms can vary from mild to severe and can include: feeling sad, thoughts of death or suicide, loss of interest, weight loss or gain unrelated to dieting, trouble sleeping, loss of energy, feeling worthless or guilty and difficulty thinking.
Paclodep 12.5 Tablet 15's is a combination of two drugs: clonazepam and paroxetine. Clonazepam increases levels of a calming chemical, gamma-amino-butyric-acid (GABA), in your brain. Paroxetine increases the serotonin hormone levels that improve mood, behaviour and prevent symptoms of depression.
You are advised to take Paclodep 12.5 Tablet 15's for as long as your doctor has prescribed it for you depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as nausea, vomiting, diarrhoea, memory impairment, uncoordinated body movements, drowsiness, low sexual desire and delayed ejaculation. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
To treat your condition effectually, continue taking Paclodep 12.5 Tablet 15's for as long as your doctor has prescribed. Do not take Paclodep 12.5 Tablet 15's if you are pregnant or breastfeeding unless prescribed by the doctor. Paclodep 12.5 Tablet 15's causes drowsiness, sleepiness, do not drive unless you are alert. Paclodep 12.5 Tablet 15's should not be given to children and adolescents aged 18 years for treating depression. Avoid consuming alcohol along with Paclodep 12.5 Tablet 15's as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.
Uses of Paclodep 12.5 Tablet 15's
Paclodep 12.5 Tablet 15's is used in the treatment of depression. The detailed uses of Paclodep 12.5 Tablet 15's are as follows:
- Treats Depression: Paclodep 12.5 Tablet 15's helps to improve mood, energy levels, and interest in daily activities by balancing natural brain chemicals.
- Manages anxiety disorders: Paclodep 12.5 Tablet 15's helps to reduce persistent worry, nervousness, and tension commonly experienced in anxiety conditions.
- Controls panic attacks: Paclodep 12.5 Tablet 15's helps to manage sudden episodes of intense fear or panic by calming brain activity and reducing overexcitement.
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Directions for Use
- Take Paclodep 12.5 Tablet 15's with or without food or as advised by a doctor.
- Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
- Swallow the medicine as a whole with glass of water.
- Do not crush, break, or chew it.
Key Benefits
Paclodep 12.5 Tablet 15's is a combination of two drugs: clonazepam and paroxetine. Clonazepam is a benzodiazepine, which works by increasing levels of a calming chemical, gamma-amino-butyric-acid (GABA), in your brain. Paroxetine is an antidepressant that increases the serotonin hormone levels that improve mood, behaviour, and prevent symptoms of depression.
How Paclodep 12.5 Tablet 15's Works
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What if I have taken an overdose of Paclodep 12.5 Tablet 15's
Drug Warnings
Do not take Paclodep 12.5 Tablet 15's if you are allergic to Paclodep 12.5 Tablet 15's or any other ingredients in it. Tell your doctor if you are taking antidepressants, antipsychotic medication, antihypertensives, or pain medication. Talk to your doctor if you have a history of seizures, bipolar disorder, suicide attempts, or schizophrenia. Patients with liver diseases, diabetes, heart disease, lung disease and bleeding disorders should use Paclodep 12.5 Tablet 15's with caution. Please do not stop the treatment abruptly as it can cause withdrawal reactions. Paclodep 12.5 Tablet 15's is not recommended to use in children and adolescents under 18 years of age as it increases suicidal tendencies in this population. Consult your doctor immediately if you experience suicidal thoughts such as killing or harming yourself while on this medication. Do not take Paclodep 12.5 Tablet 15's if you are pregnant or breastfeeding unless prescribed. Paclodep 12.5 Tablet 15's causes drowsiness and dizziness, do not drive unless you are alert. Avoid consuming alcohol along with Paclodep 12.5 Tablet 15's as it could lead to increased drowsiness and dizziness.
Drug-Drug Interactions
Drug-Drug Interactions
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Coadministration of Paclodep 12.5 Tablet with eliglustat can increase the risk of irregular heart rhythm
How to manage the interaction:
Although there is an interaction between Paclodep 12.5 Tablet and Eliglustat, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
Using tranylcypromine with Paclodep 12.5 Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Paclodep 12.5 Tablet with Tranylcypromine is not recommended, but should be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
When Paclodep 12.5 Tablet is taken with Selegiline, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).
How to manage the interaction:
Taking Paclodep 12.5 Tablet with Selegiline can possibly lead to an interaction but it can be taken if your doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, diarrhea, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Using procarbazine together with Paclodep 12.5 Tablet can increase the risk of a serious condition called the serotonin syndrome(a condition in which a chemical called serotonin increase in your body).
How to manage the interaction:
Taking Paclodep 12.5 Tablet with Procarbazine is not recommended, but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, or blurred vision contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Using Linezolid together with Paclodep 12.5 Tablet can increase the risk of a serious condition called serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a chemical that plays a role in overall wellbeing and especially a mood stabilizer).
How to manage the interaction:
Taking Paclodep 12.5 Tablet with Linezolid is not recommended but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of Paclodep 12.5 Tablet with Thioridazine can increase the risk of irregular heart rhythm.
How to manage the interaction:
Taking Thioridazine with Paclodep 12.5 Tablet is not recommended, but should be taken if advised by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Using isocarboxazid with Paclodep 12.5 Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Paclodep 12.5 Tablet with Isocarboxazid is not recommended, but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Furazolidone with Paclodep 12.5 Tablet can increase the risk of side effects
How to manage the interaction:
Taking Paclodep 12.5 Tablet with Furazolidone is not recommended, but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, or blurred vision contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Using phenelzine with Paclodep 12.5 Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Paclodep 12.5 Tablet with Phenelzine is not recommended, but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, or blurred vision contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Using Metoclopramide with Paclodep 12.5 Tablet can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhoea) to severe (muscle rigidity, fever, and seizures).
How to manage the interaction:
Taking Metoclopramide with Paclodep 12.5 Tablet is not recommended, as it can possibly lead to an interaction, it can be taken if prescribed by your doctor. Do not stop using any medications without a doctor’s advice.
Drug-Food Interactions
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Diet & Lifestyle Advise
- Maintain a healthy and well-balanced diet.
- Do not take stress as it may aggravate your condition.
- Limit alcohol intake and quit smoking.
- Engage in social activities frequently as it may improve self-esteem and confidence.
- Limit caffeine intake.
- Maintain a healthy diet and exercise regularly helps in improving overall health and boosts self-esteem.
- Regularly attend therapy sessions.
- Perform meditation and yoga. This helps in relieving stress and provides relaxation.
- Follow a regular sleep pattern to improve the amount and quality of sleep you get.
- Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
- Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in proper maintenance of neurotransmitters.
- Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
- Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.
- Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.
Habit Forming
Therapeutic Class
Alcohol
Safe if prescribed
Avoid consumption of alcohol while taking Paclodep 12.5 Tablet 15's as it may cause an increased sedative effect.
Pregnancy
Consult your doctor
Paclodep 12.5 Tablet 15's may cause toxic effects to the fetus. So, it is not recommended for use in women who are pregnant or planning to become pregnant.
Breast Feeding
Consult your doctor
Paclodep 12.5 Tablet 15's should be used with caution in breastfeeding mothers. Your doctor may advise you to stop breastfeeding while taking this medication.
Driving
Safe if prescribed
Do not drive or operate heavy machinery as Paclodep 12.5 Tablet 15's may cause drowsiness.
Liver
Consult your doctor
Paclodep 12.5 Tablet 15's should be used with caution in patients with severe liver impairment. Dose adjustments may be required in such cases.
Kidney
Consult your doctor
Paclodep 12.5 Tablet 15's should be used with caution in patients with kidney problems. Dose adjustments may be required in such cases. If you have any concerns regarding the use of Paclodep 12.5 Tablet 15's in patients with kidney problems, please consult a doctor.
Children
Safe if prescribed
Paclodep 12.5 Tablet 15's should not be used in children unless prescribed by a child specialist.
Heart
Paclodep 12.5 Tablet 15's should be taken with extreme caution in patients with heart disease. Please consult your physician.
Geriatrics
Consult your doctor
Paclodep 12.5 Tablet 15's can be given in elderly patients with extreme caution due to increased risk of adverse effects.
FAQs
Paclodep 12.5 Tablet 15's is used in the treatment of depression.
Paclodep 12.5 Tablet 15's causes sleepiness, drowsiness, and dizziness. Do not drive or operate machinery if you experience these symptoms after taking Paclodep 12.5 Tablet 15's.
Paclodep 12.5 Tablet 15's causes weight gain due to increased appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight.
Do not discontinue Paclodep 12.5 Tablet 15's without consulting your doctor as it could lead to recurring symptoms. To treat your condition effectually continue taking Paclodep 12.5 Tablet 15's for as long as prescribed. Moreover, stopping this medicine suddenly may result in withdrawal symptoms. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Paclodep 12.5 Tablet 15's.
Paclodep 12.5 Tablet 15's may cause decreased sex-drive, problems with erection and orgasm. Consult your doctor if you have any concerns regarding this.
Dry mouth could be a side-effect of Paclodep 12.5 Tablet 15's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Some patients experienced increased suicidal thoughts or actions in the first few months of the treatment with Paclodep 12.5 Tablet 15's. Report to your doctor immediately if you notice any changes in your behaviour or mood while on this medication.
Yes, the use of Paclodep 12.5 Tablet 15's can cause sleepiness as a side effect. It's important to avoid driving or operating heavy machinery until you know how Paclodep 12.5 Tablet 15's affects you.
No, it's not safe to drink alcohol while taking Paclodep 12.5 Tablet 15's. Alcohol can increase the sedative effects of Paclodep 12.5 Tablet 15's, leading to increased drowsiness and dizziness. It's best to avoid alcohol to prevent these increased side effects.
Paclodep 12.5 Tablet 15's typically takes several weeks to show full effects, but it may differ from person to person. However, it’s important to complete the full course of treatment as prescribed by your doctor.
Store the Paclodep 12.5 Tablet 15's at room temperature protected from light and moisture. Keep it out of reach of children.
The common side effects of Paclodep 12.5 Tablet 15's are nausea, vomiting, diarrhoea, memory impairment, uncoordinated body movements, drowsiness, low sexual desire and delayed ejaculation. If any of these side effects persist or worsen, please consult doctor.
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Reference
- https://www.medicines.org.uk/emc/files/pil.5833.pdf
- https://www.drugs.com/uk/pdf/leaflet/1075235.pdf
- https://www.psychiatry.org/patients-families/depression/what-is-depression
- https://www.drugs.com/drug-interactions/clonazepam-with-paxil-703-0-1800-1156.html#:~:text=clonazePAM+PARoxetine&text=Using+clonazePAM+together+with+PARoxetine,%2C+judgment%2C+and+motor+coordination.
- https://www.drugs.com/drug-interactions/paroxetine.html
- https://www.drugs.com/food-interactions/clonazepam.html
