Palestat 150mg Tablet ER belongs to a group of medicines called aldose reductase inhibitors used to manage diabetic neuropathy. Diabetic neuropathy is a chronic progressive nerve disease which causes nerve pain due to nerve damage in diabetic patients. It mostly affects the legs and feet.

Palestat 150mg Tablet ER contains ‘Epalrestat’ that works by inhibiting aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes which leads to nerve pain. Palestat 150mg Tablet ER prevents the accumulation of sorbitol, thereby helps in treating diabetic neuropathy.

You are advised to take Palestat 150mg Tablet ER for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as nausea, vomiting, diarrhoea, dizziness, and headache. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor before taking Palestat 150mg Tablet ER if you are pregnant or breastfeeding. Palestat 150mg Tablet ER may cause drowsiness and dizziness, so drive only if you are alert. Palestat 150mg Tablet ER is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Palestat 150mg Tablet ER as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Palestat 150mg Tablet ER belongs to a group of medicines called aldose reductase inhibitors. Palestat 150mg Tablet ER is used for the management of diabetic neuropathy. Palestat 150mg Tablet ER works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes which leads to nerve pain. Palestat 150mg Tablet ER prevents sorbitol accumulation, thereby treating diabetic neuropathy (pain due to nerve damage).

• Dizziness
• Nausea
• Vomiting
• Headache
• Diarrhoea

Do not take Palestat 150mg Tablet ER if you are allergic to any of its contents. Inform your doctor if you have liver or kidney problems. Consult your doctor before taking Palestat 150mg Tablet ER if you are pregnant or breastfeeding. Palestat 150mg Tablet ER may cause drowsiness and dizziness, so drive only if you are alert. Palestat 150mg Tablet ER is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Palestat 150mg Tablet ER as it could lead to increased drowsiness and sleepiness.

Drug-Drug Interactions: No interactions found/established.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: No interactions found/established.

• Include food rich in vitamin B and D in your diet.
• Include cayenne pepper in your diet as it can help lower neuropathic pain.
• Exercising regularly helps in improving overall health and combating pain. 
• Rest well, get plenty of sleep.
• Try taking a warm bath as it can be soothing.
• Avoid smoking and alcohol consumption.
• Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
• Acupuncture can be helpful by stimulating pressure points.
• Using essential oils for massages can help increase circulation.

Diabetic neuropathy: Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in the legs and feet. Diabetic neuropathic pain is common in patients with type1 and type2 diabetes, which usually develops slowly. If you have diabetes and experience numbness, pain, tingling sensation, or weakness in the hands or legs, you must consult a doctor. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty with coordination when walking, difficulty resting or sleeping, and evoked pain (pain caused by events usually not painful).