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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Paro 40 mg Tablet is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder. It contains Paroxetine, which works by increasing serotonin concentration, thereby regulating mood. This medicine may sometimes cause side effects such as insomnia, dizziness, headache, diarrhoea, nausea, fatigue, dry mouth, and loss of appetite. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

PAROXETINE-40MG

Manufacturer/Marketer :

D D Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Paro 40 mg Tablet

Paro 40 mg Tablet is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoria disorder and generalised anxiety disorder. Depression is a mood disorder characterised by sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities.

Paro 40 mg Tablet contains ‘Paroxetine,’ which works by inhibiting serotonin's reuptake, a mood-enhancing chemical messenger in the brain that communicates between brain cells.

In some cases, you may experience certain common side effects such as insomnia (difficulty sleeping), dizziness, headache, diarrhoea, nausea, fatigue, dry mouth, loss of appetite, and sexual disturbances. You are advised to talk to your doctor if the side effects persist or worsen.

Take Paro 40 mg Tablet as prescribed. You are advised to take Paro 40 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition and response to the treatment. Paro 40 mg Tablet can be taken with or without food. However, taking it with food may help reduce stomach upset. Do not crush, break, or chew it.

Do not take Paro 40 mg Tablet if you are pregnant, as it may cause harm to the fetus. Consult your doctor before taking Paro 40 mg Tablet if you are breastfeeding. Paro 40 mg Tablet is not recommended for children below 18 years, as the safety and effectiveness have not been established. Avoid consumption of alcohol while taking Paro 40 mg Tablet as it may make your symptoms or side effects worse.

Uses of Paro 40 mg Tablet

Paro 40 mg Tablet is used in the treatment of Major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder. The detailed uses of Paro 40 mg Tablet are as follows:

  • Treat depression and mood disorders: Paro 40 mg Tablet is primarily prescribed for major depressive disorder, helping improve mood, energy levels, and overall emotional well-being by increasing serotonin levels in the brain.
  • Manage anxiety-related conditions: Paro 40 mg Tablet is effective in treating generalised anxiety disorder (GAD), social anxiety disorder (SAD), panic disorder, and post-traumatic stress disorder (PTSD), reducing symptoms like excessive worry, fear, and panic attacks.
  • Control obsessive-compulsive disorder (OCD): Paro 40 mg Tablet helps reduce intrusive thoughts and compulsive behaviours by regulating serotonin activity.

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Directions for Use

  • Paro 40 mg Tablet can be taken with or without food. However, taking it with food may help reduce stomach upset.
  • It is usually taken once daily in the morning. However, your doctor may adjust the dosage of Paro 40 mg Tablet based on your medical condition.
  • Swallow Paro 40 mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Paro 40 mg Tablet belongs to a group of antidepressant medicines called selective serotonin reuptake inhibitors.
  • Paro 40 mg Tablet is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder.
  • Paro 40 mg Tablet works by inhibiting serotonin's reuptake by nerves, a mood-enhancing chemical messenger in the brain that communicates between brain cells. This helps increase serotonin concentrations in the nerve synapse, thereby regulating mood and treating depression and anxiety disorders.
  • Paro 40 mg Tablet has fewer unwanted side effects than older antidepressants and helps people recover from depression.

How Paro 40 mg Tablet Works

Paro 40 mg Tablet contains Paroxetine, which is a selective serotonin reuptake inhibitor. It works by inhibiting serotonin's reuptake, a mood-enhancing chemical messenger in the brain that communicates between brain cells. This helps increase serotonin concentrations in the nerve synapse, thereby regulating mood and treating depression and anxiety disorders.

Storage

• Store in a cool and dry place away from sunlight.• Keep Paro 40 mg Tablet out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Paro 40 mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Focus on eating nutrient-rich foods such as citrus fruits, spinach, ginger, garlic, turmeric, and fermented foods to improve immunity and general health.
  • Drink plenty of water to stay hydrated, and think about taking probiotics, zinc, vitamin C, and vitamin D supplements.
  • Adopt healthful practices such as leading a balanced lifestyle and remaining at home when necessary.
  • Avoid smoking and drinking alcohol as it can worsen your condition.
  • Drink warm fluids such as warm water with honey, broth or herbal tea to soothe sore throat.
  • Gargle with warm salt water to decrease inflammation.
  • Suck on hard candies or lozenges to increase the production of saliva and soothe your throat.
  • Avoid smoking, spicy foods, and extremely hot fluids.
  • Rest your voice and get enough sleep.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • A blocked nose can be relieved by drinking more water, which helps clear fluids.
  • Use saline nasal spray available over the counter to relieve blockage or blow harder to remove the mucus.
  • Use nasal strips that can be placed on the nose to widen nostrils and increase airflow.
  • Keep a humidifier around to moisten air at home/workplace.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.

What if I have taken an overdose of Paro 40 mg Tablet

Take Paro 40 mg Tablet only as prescribed by the doctor. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include sleepiness, nausea, vomiting, tremors, dizziness, confusion, a fast heart rate, and coma. Other symptoms observed with the overdose are dilation of the pupil, convulsions, irregular heartbeat, high/low blood pressure, aggressive reactions, liver dysfunction, state of unconsciousness, involuntary muscle contractions, rhabdomyolysis (breakdown of muscle tissue), manic reactions, acute kidney failure, urinary retention, and serotonin syndrome. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Paro 40 mg Tablet if you are allergic to any of its contents; if you are taking monoamine oxidase inhibitors (MAOI) or have taken them in the last 14 days, or if you are taking antipsychotic medicines such as thioridazine or pimozide.
  • Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself.
  • Inform your doctor if you have/had epilepsy, mania, diabetes, low sodium levels in blood, glaucoma, or are undergoing treatment for severe depression called electro-convulsive therapy.
  • Do not take Paro 40 mg Tablet if you are pregnant, as it may cause harm to the fetus.
  • Consult your doctor before taking Paro 40 mg Tablet if you are breastfeeding.
  • Avoid driving or operating machinery as Paro 40 mg Tablet may cause dizziness, confusion, sleepiness and blurred vision.
  • Paro 40 mg Tablet is not recommended for children below 18 years, as the safety and effectiveness have not been established.
  • Avoid consumption of alcohol while taking Paro 40 mg Tablet as it may make your symptoms or side effects worse.

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical
How does the drug interact with Paro 40 mg Tablet:
Co-administration of Rilpivirine is taken with Paro 40 mg Tablet, can decrease the absorption and blood levels of Rilpivirine and make the medication less effective.

How to manage the interaction:
Taking Paro 40 mg Tablet with Rilpivirine can lead to an interaction, please consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Paro 40 mg Tablet:
Co-administration of Paro 40 mg Tablet reduces stomach acid, decreases the absorption and blood levels of Atazanavir, and reduces its effectiveness.

How to manage the interaction:
Taking Paro 40 mg Tablet with Atazanavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
How does the drug interact with Paro 40 mg Tablet:
Taking Gefitinib with Paro 40 mg Tablet reduces the acidity level in the stomach and may interfere with the absorption of Gefitinib and reduce its effectiveness.

How to manage the interaction:
Taking Paro 40 mg Tablet with Gefitinib together can possibly result in an interaction, it can be taken if your doctor has advised it. You are recommended to take gefitinib 12 hours before or 12 hours after Paro 40 mg Tablet to help minimize the impact of the interaction. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Paro 40 mg Tablet:
Taking Paro 40 mg Tablet with Pazopanib may reduce the effectiveness of pazopanib.

How to manage the interaction:
If you are supposed to take Paro 40 mg Tablet and Pazopanib together, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Paro 40 mg Tablet:
Co-administration of Methotrexate with Paro 40 mg Tablet can increase the levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Paro 40 mg Tablet and methotrexate, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, or dizziness, consult a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Paro 40 mg Tablet:
Taking Erlotinib with Paro 40 mg Tablet may interfere with the absorption of Erlotinib into the bloodstream, and reduce its effectiveness.

How to manage the interaction:
Taking Paro 40 mg Tablet with Erlotinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
How does the drug interact with Paro 40 mg Tablet:
Taking Dasatinib with Paro 40 mg Tablet may decrease the blood levels of Dasatinib and reduce its effectiveness.

How to manage the interaction:
Taking Paro 40 mg Tablet with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. In case of any unusual side effects, contact a doctor. Do not stop using any medications without a doctor's advice.
PantoprazoleNelfinavir
Severe
How does the drug interact with Paro 40 mg Tablet:
Taking Nelfinavir with Paro 40 mg Tablet may decrease the absorption and blood levels of Nelfinavir and reduce its effectiveness.

How to manage the interaction:
Taking Paro 40 mg Tablet with Nelfinavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
How does the drug interact with Paro 40 mg Tablet:
Taking Paro 40 mg Tablet can make Dacomitinib less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Paro 40 mg Tablet with Dacomitinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly, as it helps in improving overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters.
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
  • Exercising helps in the production of the body’s natural antidepressants. It also helps relieve stress, improve mood, boost self-esteem, and promote restful sleep.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

PSYCHOTHERAPEUTICS
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Paro 40 mg Tablet as it may make your symptoms or side effects worse.

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Pregnancy

Unsafe

Paro 40 mg Tablet belongs to pregnancy category D. It is not recommended to take Paro 40 mg Tablet if you are pregnant or planning for pregnancy, as Paro 40 mg Tablet might cause fetal harm.

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Breast Feeding

Consult your doctor

Paro 40 mg Tablet may pass into breastmilk. Consult your doctor before taking Paro 40 mg Tablet ; your doctor will decide whether Paro 40 mg Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Avoid driving or operating machinery as Paro 40 mg Tablet may cause dizziness, confusion, sleepiness and blurred vision.

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Liver

Consult your doctor

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Paro 40 mg Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established.

FAQs

Paro 40 mg Tablet is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder.

Paro 40 mg Tablet works by inhibiting serotonin's reuptake by nerves, a mood-enhancing chemical messenger in the brain that communicates between brain cells. This increases serotonin concentrations in the nerve synapse, thereby helping in regulating mood.

Do not discontinue Paro 40 mg Tablet without consulting your doctor, as it could lead to withdrawal effects. To treat your condition effectually, continue taking Paro 40 mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Paro 40 mg Tablet ; the doctor may reduce the dose gradually.

Paro 40 mg Tablet may cause decreased libido (sex drive), impotence (erectile dysfunction), abnormal ejaculation and problems with orgasm. Consult your doctor if you have any concerns regarding this.

Dry mouth could be a side effect of Paro 40 mg Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy may stimulate saliva and prevent mouth dryness.

Please consult your doctor before taking Paro 40 mg Tablet if you have glaucoma, as Paro 40 mg Tablet might cause increased pressure in the eye.

Consult your doctor before taking Paro 40 mg Tablet if you have diabetes, as Paro 40 mg Tablet might fluctuate blood glucose levels. Regular monitoring of blood sugar levels is advised if you are taking Paro 40 mg Tablet . Talk to your doctor if your blood sugar levels are unstable.

People taking antidepressants such as Paro 40 mg Tablet are more likely to develop suicidal thoughts. Talk to your doctor immediately if you have thoughts of harming or killing yourself.

Consult your doctor before taking tamoxifen (used to treat cancer) along with Paro 40 mg Tablet as Paro 40 mg Tablet might make tamoxifen less effective.

Paro 40 mg Tablet may cause unusual bleeding or bruising, such as vomiting blood or passing blood in stools. Therefore, talk to your doctor before taking Paro 40 mg Tablet if you have a history of bleeding disorders or if you are taking medicines that might increase the risk of bleeding such as blood thinners (warfarin), anti-psychotics (perphenazine or clozapine), tricyclic antidepressants (clomipramine), or NSAID's (acetylsalicylic acid, ibuprofen, celecoxib, etodolac, diclofenac, meloxicam).

Paro 40 mg Tablet may cause side effects such as nausea, headache, diarrhea, dry mouth, fatigue (overtiredness), loss of appetite and insomnia (difficulty sleeping). If these side effects persist or worsen, please consult your doctor.

Yes, bone fractures have been associated with Paro 40 mg Tablet .

The risk of serotonin syndrome is increased when Paro 40 mg Tablet is taken together with other serotonergic medicines, including tricyclic antidepressants, fentanyl, triptans, tramadol, buspirone, lithium, tryptophan, thioridazine, isocarboxazid, pimozide, intravenous methylene blue, linezolid, amphetamines, procarbazine, phenelzine, selegiline, tranylcypromine and St. John’s Wort.

You may start noticing an improvement in your symptoms after 1-2 weeks of starting the treatment with Paro 40 mg Tablet . If you do not see any improvement, do not stop taking Paro 40 mg Tablet and consult your doctor. It may take around 4-6 weeks to see the full effects of Paro 40 mg Tablet .

No, do not stop taking Paro 40 mg Tablet suddenly, without first consulting your doctor. This is a common problem with Paro 40 mg Tablet that you may feel your symptoms have worsened initially, but the benefits start showing after 1-2 weeks. You must consult your doctor if the worsening does not improve even after 1-2 weeks.

Paro 40 mg Tablet is not recommended for children and adolescents below 18 years of age as patients in this age group have an increased risk of experiencing side effects such as aggression, suicidal thoughts, oppositional behaviour and anger when they take Paro 40 mg Tablet . If you have any concerns regarding this, please discuss with your doctor.

No, do not take Paro 40 mg Tablet if you are receiving tamoxifen. Tamoxifen often causes hot flashes (episodes of feeling extremely hot), which can be treated with Paro 40 mg Tablet . However, Paro 40 mg Tablet may make tamoxifen less effective and can lead to recurrence of breast cancer.

Yes, you need to be careful while taking Paro 40 mg Tablet if you are a diabetic, as Paro 40 mg Tablet may change your blood sugar levels. Thus, may need a dose adjustment of your insulin or antidiabetic medicines. Discuss with your doctor regarding this and monitor your blood sugar levels regularly.

Paro 40 mg Tablet is usually considered safe if taken as advised by a doctor. However, it may cause side effects, just like any medication. Discuss your concerns or potential risks with your doctor before starting Paro 40 mg Tablet .

No, Paro 40 mg Tablet is not a sleeping pill. Although its calming effect can promote better sleep, its main purpose is to manage depression and anxiety symptoms.

Your doctor determines the best time to take Paro 40 mg Tablet . It can be taken with or without food, but follow your doctor's instructions for dosage and timing.

It may take a few weeks for Paro 40 mg Tablet to show improvements in your symptoms. Even if you do not see immediate results, it is important to keep taking it as prescribed by your doctor.

Yes, Paro 40 mg Tablet helps manage various anxiety disorders such as obsessive-compulsive disorder and panic disorder. It helps reduce anxiety symptoms by restoring the balance of serotonin in the brain.

If you experience any side effects while taking Paro 40 mg Tablet , inform your doctor immediately. After analysing your symptoms, they will modify your treatment plan.

Country of origin

India

Manufacturer/Marketer address

G-1/583,585,586 Sitapura Industrial Area, Riico, Tonk Road, Jaipur (Rajasthan)-302022.
Other Info - PAR1255

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