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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Pearl Oral Contraceptive Pills is used for contraception and treating dysmenorrhea (irregular and painful periods). It contains Ethinylestradiol and Levonorgestrel, which maintains a normal menstrual cycle (periods) in women. It works by fulfilling the deficiency of estrogen hormone, thereby preventing symptoms like night sweats, hot flashes, and mood swings. Also, it prevents the release of an egg from the ovary (female reproductive cells) or prevents fertilization of an egg by sperm (male reproductive cells). It may also change the lining of the uterus to prevent the development of a pregnancy. It may cause side effects such as stomach pain, headache, nausea, breast pain, weight gain, and irregular uterine bleeding. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

PSI India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pearl Oral Contraceptive Pills

Pearl Oral Contraceptive Pills belongs to a group of medications called 'hormonal contraceptives' primarily used for contraception and treating dysmenorrhea (irregular and painful periods). Contraception is a procedure that aims to prevent unwanted pregnancy for safe family planning. Dysmenorrhea is an irregular and painful menstrual period leading to abdominal pain, mood swings, digestion problems, fainting, vomiting, and nausea.

Pearl Oral Contraceptive Pills is a combination of two medications: Ethinylestradiol and Levonorgestrel. Ethinylestradiol is a synthetic female hormone (estrogen) that maintains a normal menstrual cycle (periods) in women. It works by fulfilling the deficiency of estrogen hormone, thereby preventing symptoms like night sweats, hot flashes, and mood swings. Levonorgestrel is a progestin (female sex hormones) that prevents the release of an egg from the ovary (female reproductive cells) or prevents fertilization of an egg by sperm (male reproductive cells). Pearl Oral Contraceptive Pills may also change the lining of the uterus to prevent the development of a pregnancy. Thus, together, Pearl Oral Contraceptive Pills helps prevent pregnancy.

Take Pearl Oral Contraceptive Pills  as prescribed by your doctor. Pearl Oral Contraceptive Pills can be taken with or without food but take it simultaneously every day for best results. Depending on your medical condition, you are advised to take Pearl Oral Contraceptive Pills for as long as your doctor has prescribed it for you. You may experience stomach pain, headache, nausea, breast pain, weight gain, and irregular uterine bleeding. Most of these side effects of Pearl Oral Contraceptive Pills do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Do not use Pearl Oral Contraceptive Pills if you are pregnant or have recently delivered a baby.

Inform your doctor before starting to Pearl Oral Contraceptive Pills if you are over 35 years or ever have a heart problem, cancer (breast, uterus, or vagina), uterine bleeding, liver, or kidney problems. Do not take Pearl Oral Contraceptive Pills if you are pregnant already or a breastfeeding mother. Pearl Oral Contraceptive Pills does not prevent the transmission of any sexually transmitted disease (STD), so use some other form of contraception (condom) during sexual intercourse if you have any STD or AIDS (acquired immunodeficiency syndrome).

Uses of Pearl Oral Contraceptive Pills

Treatment of Contraception, Dysmenorrhea (irregular menstrual periods).

Directions for Use

Swallow the medicine as a whole with water; do not crush or chew it.

Medicinal Benefits

Pearl Oral Contraceptive Pills is an oral hormonal combination drug, Ethinylestradiol and Levonorgestrel, primarily used for contraception. Pearl Oral Contraceptive Pills contains two female sex hormones, progestin (levonorgestrel) and estrogen (ethinylestradiol), which help prevent pregnancy in multiple ways. It prevents the release of an egg from the ovaries and makes the fluid present in the cervix difficult for sperm to enter the womb. In addition, it prevents the thickening of the uterus's inner wall, which is necessary for an egg to grow and multiply. Pearl Oral Contraceptive Pills is generally taken for 21 days starting from day one of the menstrual cycle, and then for the next seven days, it is not taken, and the same course is repeated.

How Pearl Oral Contraceptive Pills Works

Pearl Oral Contraceptive Pills is a combination of two medications: Ethinylestradiol and Levonorgestrel. Ethinylestradiol is a synthetic female hormone (estrogen) that maintains a normal menstrual cycle (periods) in women. It works by fulfilling the deficiency of estrogen hormone, thereby preventing symptoms like night sweats, hot flashes, and mood swings. Levonorgestrel is a progestin (female sex hormones) that prevents the release of an egg from the ovary (female reproductive cells) or prevents fertilization of an egg by sperm (male reproductive cells). Pearl Oral Contraceptive Pills may also change the lining of the uterus to prevent the development of a pregnancy. Thus, together, Pearl Oral Contraceptive Pills helps prevent pregnancy.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pearl Oral Contraceptive Pills

  • Headache
  • Weight gain
  • Acne (pimples)
  • Stomach pain/cramps
  • Tiredness
  • Depression

What if I have taken an overdose of Pearl Oral Contraceptive Pills

Do not take more than the prescribed dose of Pearl Oral Contraceptive Pills as it may cause overdose. The symptoms of overdose include vomiting, nausea, drowsiness, fatigue (overtired) and withdrawal bleeding in females. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Please inform your doctor if you have ever had heart disease, hypertension, obesity, cancer (breast, cervix, or uterus), diabetes mellitus, liver or kidney disease, or abnormal uterine bleeding as Pearl Oral Contraceptive Pills is known to contra-indicate. Check your breast every month for changes, such as if you feel lumps or see anything odd, please inform your doctor. Smoking may increase the risk of cardiovascular disease in women over 35 years when taking Pearl Oral Contraceptive Pills . Pearl Oral Contraceptive Pills does not protect against any sexually transmitted disease or HIV. If pregnancy occurs while you are taking Pearl Oral Contraceptive Pills , please consult your doctor. Do not start using a new medication without telling your doctor. Sometimes, you may experience spotting or bleeding in between missed periods or menstrual periods. If the spotting persists, please consult your doctor. Do not use Pearl Oral Contraceptive Pills if you are pregnant or have recently delivered a baby. If you have missed a dose or are late by 12 hours, please wear a condom for two days while sexual intercourse to avoid unwanted pregnancy. Do not take medicine if you are pregnant already or breastfeeding. If you have migraines, please inform your doctor, as taking Pearl Oral Contraceptive Pills may increase your headache.

Drug-Drug Interactions

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LevonorgestrelAcitretin
Critical
LevonorgestrelTranexamic acid
Critical

Drug-Drug Interactions

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LevonorgestrelAcitretin
Critical
How does the drug interact with Pearl Oral Contraceptive Pills:
Coadministration of Acitretin with Pearl Oral Contraceptive Pills can increase the risk and severity of birth defects in unborn when taken by a pregnant woman.

How to manage the interaction:
Taking Acitretin with Pearl Oral Contraceptive Pills together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Consult a doctor if you get pregnant while taking these medications. Never use acitretin if you are pregnant. Do not stop using any medications without talking to a doctor.
LevonorgestrelTranexamic acid
Critical
How does the drug interact with Pearl Oral Contraceptive Pills:
Taking Pearl Oral Contraceptive Pills with Tranexamic acid may increase the risk of blood clot formation which can lead to serious conditions such as heart problems and kidney failure.

How to manage the interaction:
Taking Tranexamic acid with Pearl Oral Contraceptive Pills may leads to an interaction but can be taken if prescribed by the doctor. However, if you experience chest pain; shortness of breath; coughing up blood; blood in the urine; sudden loss of vision; and pain, redness, or swelling in your arm or leg, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
LevonorgestrelEtretinate
Critical
How does the drug interact with Pearl Oral Contraceptive Pills:
Using etretinate and Pearl Oral Contraceptive Pills can cause severe birth defects.

How to manage the interaction:
Taking Etretinate with Pearl Oral Contraceptive Pills can cause an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
EthinylestradiolTranexamic acid
Critical
How does the drug interact with Pearl Oral Contraceptive Pills:
Taking Pearl Oral Contraceptive Pills with Tranexamic acid may increase the risk of blood clot formation.

How to manage the interaction:
Taking Pearl Oral Contraceptive Pills with Tranexamic acid is not recommended, as it can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult doctor immediately. Do not stop using any medications without talking to a doctor.
LevonorgestrelMycophenolate Mofetil
Severe
How does the drug interact with Pearl Oral Contraceptive Pills:
Taking Pearl Oral Contraceptive Pills with Mycophenolate mofetil can decrease the levels of Pearl Oral Contraceptive Pills in the body. This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Although taking Mycophenolate Mofetil and Pearl Oral Contraceptive Pills together can cause an interaction, it can be taken if a doctor has suggested it. Contact a doctor if you experience worsening of your symptoms such as hot flashes, vaginal dryness, or abnormal bleeding. Do not discontinue any medication without consulting a doctor.
LevonorgestrelBrigatinib
Severe
How does the drug interact with Pearl Oral Contraceptive Pills:
Brigatinib may lower the blood levels and effects of Pearl Oral Contraceptive Pills, making it less effective as a type of birth control. It has also been linked to serious birth abnormalities in newborn children.

How to manage the interaction:
Although taking Pearl Oral Contraceptive Pills and brigatinib can lead to an interaction, it can be taken if prescribed by a doctor. If you have been receiving hormone replacement therapy for menopause, you should contact a doctor if you notice an increase in the frequency or severity of your symptoms, such as hot flashes, vaginal dryness, or irregular bleeding. Do not stop using any medications without talking to a doctor.
LevonorgestrelCarfilzomib
Severe
How does the drug interact with Pearl Oral Contraceptive Pills:
Carfilzomib can occasionally cause dangerous blood clots and using it together with Pearl Oral Contraceptive Pills may increase the risk.

How to manage the interaction:
Co-administration of Carfilzomib with Pearl Oral Contraceptive Pills can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away: blood clots that can be harmful, high blood pressure or cholesterol, heart problems like heart attack or blockage in the lung, stroke, complications, chest pain, difficulty breathing, coughing up blood, sudden vision loss, pain, redness, or swelling in an arm or leg, and numbness or weakness on one side of your body. Do not discontinue any medications without consulting a doctor.
LevonorgestrelGriseofulvin
Severe
How does the drug interact with Pearl Oral Contraceptive Pills:
Using Pearl Oral Contraceptive Pills with griseofulvin may reduce Pearl Oral Contraceptive Pills blood levels and effects.

How to manage the interaction:
Although taking Pearl Oral Contraceptive Pills and griseofulvin together can result in an interaction, it can be taken if a doctor has prescribed it. If you use hormone replacement treatment(Pearl Oral Contraceptive Pills) for menopause, consult the doctor if your symptoms do not improve or if you begin to bleed abnormally. Do not discontinue any medications without consulting a doctor.
LevonorgestrelOxcarbazepine
Severe
How does the drug interact with Pearl Oral Contraceptive Pills:
Taking Pearl Oral Contraceptive Pills and Oxcarbazepine may lower Pearl Oral Contraceptive Pills blood levels and effects.

How to manage the interaction:
Although taking Pearl Oral Contraceptive Pills and oxcarbazepine together can result in an interaction, it can be taken if a doctor has prescribed it. If you use hormone replacement treatment (Pearl Oral Contraceptive Pills) for menopause, consult the doctor if your symptoms do not improve or if you begin to bleed abnormally. Do not stop using any medications without talking to a doctor.
LevonorgestrelRifapentine
Severe
How does the drug interact with Pearl Oral Contraceptive Pills:
Taking Pearl Oral Contraceptive Pills and Rifapentine may lower Pearl Oral Contraceptive Pills blood levels and effects.

How to manage the interaction:
Although taking Pearl Oral Contraceptive Pills and rifapentine together can result in an interaction, they can be taken if a doctor has prescribed it. If you use hormone replacement treatment(Pearl Oral Contraceptive Pills) for menopause, consult the doctor if your symptoms do not improve or if you begin to bleed abnormally. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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ETHINYLESTRADIOL-0.03MG+LEVONORGESTREL-0.15MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ETHINYLESTRADIOL-0.03MG+LEVONORGESTREL-0.15MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice

How to manage the interaction:
Taking Grapefruit or Grapefruit juice while on the treatment with Ethinylestradiol, Levonorgestrel can lead to increase in blood levels of Ethinylestradiol, Levonorgestrel. Avoid or limit the consumption of grapefruit and grapefruit juice during treatment with Ethinylestradiol, Levonorgestrel.

Diet & Lifestyle Advise

  • ​​Keep your weight under control with a body mass index (BMI) of 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Including heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.
  • Do regular exercise to maintain weight fluctuations caused due to Pearl Oral Contraceptive Pills .
  • Avoid chronic stress and exercise like running, as it might increase vaginal bleeding.
  • Monitor your blood pressure daily and if there is too much fluctuation, immediately contact your doctor.
  • Monitor your blood sugar level and blood pressure regularly to avoid any complications.
  • Quitting smoking and not drinking alcohol is the best strategy to lower the risk of any complications.

Habit Forming

No

Therapeutic Class

CONTRACEPTIVES

Pearl Oral Contraceptive Pills Substitute

Substitutes safety advice
  • Ovral L Tablet 21's

    by Others

    2.79per tablet
  • Ovipauz L Tablet 21's

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    2.79per tablet
  • Divacon Tablet 21's

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    2.85per tablet
  • Planit Tablet 21's

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    3.55per tablet
  • Oral-L Tablet 21's

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    3.44per tablet
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Pearl Oral Contraceptive Pills to avoid unpleasant side effects.

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Pregnancy

Unsafe

Caution should be exercised. Hormonal medicines can affect the developing baby. It is advisable to consult a doctor before using it.

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Breast Feeding

Unsafe

Not safe; this Pearl Oral Contraceptive Pills may pass into breast milk. They may harm the baby and also may affect the production of milk. So, this Pearl Oral Contraceptive Pills is unsafe for breastfeeding mothers.

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Driving

Caution

Pearl Oral Contraceptive Pills has no or negligible influence on the ability to drive or use machines.

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Liver

Caution

Pearl Oral Contraceptive Pills to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Pearl Oral Contraceptive Pills to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Pearl Oral Contraceptive Pills is not recommended for children. Safety and efficacy of Pearl Oral Contraceptive Pills are established in women of reproductive age. But sufficient studies have not been performed on women less than 16 years of age. So, take Pearl Oral Contraceptive Pills only when prescribed by a doctor.

FAQs

Pearl Oral Contraceptive Pills is used for contraception and treating dysmenorrhea (irregular and painful periods).

Yes, Pearl Oral Contraceptive Pills can cause spotting in between the regular periods. Usually, it does not persist, but if spotting does not, please inform your doctor, as medical attention may be required.

Yes, Pearl Oral Contraceptive Pills is known to cause weight gain. So, avoid weight gain, exercise regularly, and eat home-cooked food.

No, the Pearl Oral Contraceptive Pills does not protect against sexually transmitted diseases (STDs). It is an oral form of contraception that does not protect against STDs. So, use some other form of contraception, like condoms, to avoid transmission.

You will usually get your period within three days after taking the last pill. If you have not followed the dosing schedule like you have missed one or two pills or started taking them a day after, you should have the probability of pregnancy at the time of the first missed period, and you should contact your doctor.

Do not take Pearl Oral Contraceptive Pills if you have a heart fitted with an artificial valve, heart diseases like high blood pressure or high blood cholesterol levels (increased fat in your blood), confirmed or suspected ectopic pregnancy, have asthma, have blood clot problems, have a bleeding disorder, have liver or kidney disease, have anaemia (low haemoglobin) or otherwise malnourished. Taking Pearl Oral Contraceptive Pills in these conditions can cause life-threatening conditions in an individual.

If you forget to take one tablet of Pearl Oral Contraceptive Pills , take it as soon as you remember, even if it means taking two tablets at the same time and then follow the usual dosing schedule. However, if you forget to take two or more doses, you may not be completely protected against pregnancy. In this case, start taking the Pearl Oral Contraceptive Pills as soon as you remember and use a non-hormonal method of contraception such as condoms for at least the next 7 days to prevent pregnancy. Frequent missing doses may cause spotting (bloodstain) or unexpected vaginal bleeding. If this persists, contact your doctor.

Pearl Oral Contraceptive Pills is contraindicated in women with a history of breast and cervical cancer. Women with known or suspected carcinoma of the breast or personal history of breast cancer should not use Pearl Oral Contraceptive Pills because breast cancer is usually a hormonally-sensitive tumor, and Pearl Oral Contraceptive Pills slightly increases your risk of breast cancer.Therefore, inform your doctor if you have had a history of breast cancer before taking Pearl Oral Contraceptive Pills .

Country of origin

India

Manufacturer/Marketer address

Ground Floor, Psi India Pvt Ltd, 8, Guru Ravidas Marg, Balaji Estate, Kalkaji, New Delhi, Delhi 110019
Other Info - PEA0188

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