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compositionComposition:PEGFILGRASTIM-6MG
prescriptionPrescription Medicine
Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml belongs to the class of medicine called hematopoietic agents used in the treatment of neutropenia. It helps reduce the chances of infection in cancer patients by stimulating the formation of white blood cells. Common side effects include nausea, headaches, bone pain, pain in the extremity, and injection site reactions.
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

PEGFILGRASTIM-6MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

Parenteral

Return Policy :

Not Returnable

About Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml

Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml belongs to the class of medicine called 'hematopoietic agent' used to treat neutropenia, a deficiency of specific white blood cells caused by cancer, bone marrow transplant, chemotherapy, or other diseases. Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml helps reduce the chance of infection in cancer patients and those receiving chemotherapy medicines. Neutropenia is a condition in which the quantity of neutrophils (white blood cells) in the blood is reduced.

Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml contains 'Pegfilgrastim,' a growth factor that stimulates the formation of white blood cells and helps reduce the chances of infection in cancer patients receiving chemotherapy.

Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml will be administered by a healthcare professional. Sometimes, you may experience injection site responses such as pain, redness, or swelling. You may also experience nausea, headaches, bone pain and pain in the extremity. Most of these side effects do not necessitate medical treatment and will gradually fade over time. However, if you suffer these side effects regularly, you should consult your doctor.

Do not use Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml without the doctor's advice if you have a skin reaction or irritation to any medicine. Consult your doctor before using the Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml if you are pregnant or breastfeeding. Let your doctor know if you suffer from renal dysfunction, blood cancer, or leucocytosis (high white blood cell count). Regular blood tests are recommended to check the number of white blood cells in the body. Keep your doctor informed about your medical condition and all the medicines you take to rule out any side effects.

Uses of Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml

Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml is used in the treatment of neutropenia. The detailed uses of Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml are as follows:

  • Prevents Chemotherapy-Induced Neutropenia: Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml helps stimulate the formation of neutrophils (a type of white blood cell) in cancer patients receiving chemotherapy.
  • Reduces Infection Risk: By increasing white blood cells, Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml helps lower the chances of infections during chemotherapy, when the immune system is weakened.
  • Reduces Febrile Neutropenia Risk: Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml helps prevent febrile neutropenia (fever with low neutrophil count), a serious complication of chemotherapy.
  • Additional Therapeutic Applications: Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml may be prescribed to boost white blood cell count following bone marrow transplantation, severe persistent neutropenia, neutropenia in HIV patients, and before stem cell donation.

Key Benefits

Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml contains 'Pegfilgrastim,' which is a growth factor. It belongs to the cytokine family of proteins and is extremely similar to a natural protein (granulocyte-colony stimulating factor) produced by the body. Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml acts by encouraging the bone marrow to generate more white blood cells, aiding infection resistance. Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml is used to boost white blood cell count following cancer treatment or chemotherapy, bone marrow transplantation, severe persistent neutropenia, neutropenia in HIV patients, and before stem cell donation.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml may be administered by your doctor, or you may be told to inject the medication yourself at home. Your doctor will train you on how to use Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml at home.
  • Check the label for directions and use it as advised by the doctor.
  • Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml should be administered subcutaneously (under the skin) in the thighs, abdomen, buttocks, or upper arm.
  • Rotate the injection site each time.
  • Do not inject into the areas where the skin is tender, red, bruised, hard, scarred, or has stretch marks.

How Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml Works

Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml contains 'Pegfilgrastim,' a growth factor that stimulates the formation of white blood cells and helps reduce the chances of infection in cancer patients receiving chemotherapy.
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Alcohol

Caution

It is unknown whether consuming alcohol with Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml is safe. However, as a precaution, it is best to avoid or limit alcohol consumption.

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Pregnancy

Caution

Pregnancy Category C. It should be used in pregnant women only if clinically needed, and the benefits outweigh the risks. Please consult your doctor.

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Breast Feeding

Caution

It is unknown whether Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml passes into the breast milk. Please seek medical advice from your doctor if you are breastfeeding before taking Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml.

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Driving

Safe if prescribed

The ability to drive or utilize machines is unaffected by Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml.

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Liver

Caution

Consult your doctor if you have liver problems.

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Kidney

Caution

Caution should be exercised while using Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml in patients with renal dysfunction. Monitoring of patients with renal dysfunction is recommended.

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Children

Caution

Please consult your doctor if you have any concerns regarding the usage of Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml in children.

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Heart

Caution

Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml should be used with caution in patients with heart conditions, as it may increase the risk of side effects. Please inform your doctor if you have any heart problems before receiving Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml.

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Geriatrics

Caution

Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include bone pain, swelling, and shortness of breath. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Consume a well-balanced and healthy food to aid in your recovery.
  • Avoid eating processed food or frozen food. 
  • Consume antioxidant-rich foods such as berries, spinach, kidney beans, dark chocolate, and so on.
  • Flavonoid-rich foods aid in the reduction of inflammation. Soy, berries, broccoli, grapes, and green tea are examples.
  • Limit or quit the consumption of alcohol.
  • Quit smoking.

Have a query?

How Soon It Starts Working

The time required for Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml to start to work: Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml ideally shows its action within 24 hours after administration. The time for which the effects of Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml last: The effect of Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml lasts for several days.

What if you forget to take Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml

Use the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not use a double dose to make up for the missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml out of sight and reach of children. • Cold chain - To be stored in cold places at 2ºC to 8ºC

Drug Warnings

Do not use Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml without the doctor's advice if you had a skin reaction or irritation to any medicine. Consult your doctor before using Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml if you are pregnant or breastfeeding. Let your doctor know if you are suffering from renal dysfunction, blood cancer, leucocytosis (high white blood cell count). Keep your doctor informed about your medical condition and all the medicines you are taking to rule out any side effects. Regular blood tests will be taken to monitor the number of white blood cells in the body. Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml is a cold chain medicine, and so it has to be stored in the refrigerator between 2-8 degrees Celsius else its efficacy might get lost.

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Drug-Drug Interactions: Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml may have interaction with medicines used to treat cancer (e.g. cladribine) and other hematopoietic agents (e.g. filgrastim).

Drug-Food Interactions:  Limit or quit the consumption of alcohol.

Drug-Disease Interactions: Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml may cause interactions with disease conditions such as glomerulonephritis (acute inflammation of the kidney), leucocytosis (high white blood cell count) and myeloid tumours (cancer).

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Habit Forming

No

Therapeutic Class

[HEMATOPOIETIC]

FAQs

Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml belongs to the class of medicine called 'hematopoietic agent' used to treat neutropenia, a deficiency of specific white blood cells caused by cancer, bone marrow transplant, chemotherapy, or other diseases.

Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml contains 'Pegfilgrastim,' which is a growth factor that stimulates the formation of white blood cells and helps to reduce the chances of infection in cancer patients receiving chemotherapy.

This medication should not be used in individuals who have a known allergy to filgrastim, pegfilgrastim, or any of the inactive components present in it.

Yes, Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml may interfere with certain lab tests, such as bone imaging and blood testing, potentially resulting in incorrect test findings. Make sure your doctor and laboratory personnel are aware that you take Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml.

Peg-Grafeel+ Pfs 6 mg Injection 0.6 ml may sometimes cause capillary leak syndrome, a condition that causes blood leakage from small blood vessels. Inform your doctor immediately if you notice difficulty breathing, swelling, a feeling of fullness, and tiredness.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy'S Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, India.
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