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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Medopharm Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Pegawin Tablet

Pegawin Tablet is a prescription medication primarily used to manage neuropathic pain, which is nerve pain caused by damage to the nervous system. It is commonly prescribed for conditions such as diabetic neuropathy, shingles (post-herpetic neuralgia), and peripheral neuropathy. By targeting the source of nerve irritation and supporting nerve health, it helps reduce uncomfortable sensations like burning, tingling, and sharp pain.

To get the best results, you should take Pegawin Tablet daily and consistently at the same times each day. You can take this medication with or without food, though taking it with a glass of water is recommended. Incorporating simple lifestyle changes, such as keeping your blood sugar steady and engaging in light daily movement, can significantly support your recovery process.

While taking Pegawin Tablet , some people may experience mild side effects like dizziness or sleepiness. These are usually temporary as your body adjusts to the medication, but you must contact your doctor immediately if you experience serious issues, such as difficulty breathing, swelling in your throat, or sudden changes in your mood.

Before you begin taking Pegawin Tablet , it is important to discuss your medical history with your doctor, especially if you have kidney disease, heart problems, or a history of substance misuse. Do not take this if you have a known allergy to any of the active ingredients in this medication.

This medicine can interact with alcohol and certain other prescription drugs, such as strong pain relievers or sleeping aids, which can cause extreme drowsiness. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, please consult your doctor to ensure this medication is safe for your specific situation.

Uses of Pegawin Tablet

Pegawin Tablet is commonly prescribed to manage nerve-related pain while also providing nutritional support that helps maintain healthy nerve function:

  • Neuropathic Pain: It calms overactive nerves in the brain and spinal cord to relieve chronic, burning, or shooting pain.
  • Peripheral Neuropathy: It helps repair and regenerate damaged peripheral nerve fibers, especially in the hands and feet.
  • Nutritional Deficiencies: It replenishes essential B-vitamins that are crucial for maintaining the structural integrity of your nervous system.

 

Key Benefits

By combining nerve-calming medication with important neurotropic vitamins, this medicine provides both symptom relief and nutritional support for nerve health:

  • Relieves Persistent Nerve Pain: Helps reduce the intensity of chronic nerve-related symptoms such as burning, stabbing, tingling, or electric shock-like sensations.
  • Promotes Better Sleep Quality: By easing discomfort that can worsen at night, it may help improve sleep quality and provide more restful nights.
  • Supports Nerve Repair and Recovery: Supplies essential nutrients that contribute to the maintenance, protection, and recovery of damaged nerve cells.
  • Improves Mobility and Daily Function: Reduced pain and discomfort can make it easier to walk, perform daily tasks, and participate in routine physical activities.
  • Provides Comprehensive Nerve Support: Combines pain management with vitamin supplementation, addressing both the symptoms and nutritional needs associated with certain nerve disorders.
     

Directions for Use

Follow these guidelines to take your medication safely and effectively:

  • Swallow the capsule or tablet whole with a glass of water. Do not chew, crush, or break it.
  • You may take this medicine with or without food.
  • Try to take your dose at the same time every day to keep a steady amount of the medicine in your system.
  • Always follow your doctor's exact instructions regarding how and when to take your medication.
     

How Pegawin Tablet Works

Pegawin Tablet contains five active medicines that work together to relieve nerve pain and support the repair and health of damaged nerves. Pregabalin works by binding to specific calcium channels (alpha-2-delta subunits) on nerve cells within the central nervous system. This reduces the release of certain chemical messengers involved in pain signalling, helping to calm overactive nerves and decrease sensations such as burning, tingling, stabbing pain, and numbness associated with nerve damage. Methylcobalamin is an active form of vitamin B12 that helps maintain healthy nerve function. It supports the production of myelin, the protective covering around nerve fibres, which helps promote nerve repair and regeneration. Benfotiamine is a fat-soluble form of vitamin B1 that is easily absorbed by nerve cells. It helps protect nerves from damage, particularly damage associated with high blood sugar levels, and supports overall nerve health. Pyridoxine (Vitamin B6) is an essential vitamin that plays an important role in normal nerve function. It helps the body produce chemical messengers involved in nerve signalling and supports the healthy functioning of the nervous system. Folic acid is a form of vitamin B9 that supports cell growth and tissue repair. It helps provide the nutrients needed for the maintenance and recovery of damaged nerve tissues. Together, these medicines help reduce nerve pain, support nerve repair, improve nerve function, and promote overall nervous system health.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Pegawin Tablet as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Avoid taking Pegawin Tablet if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Pegawin Tablet , your doctor will decide whether Pegawin Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Pegawin Tablet causes drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Pegawin Tablet should not be given to children as the safety and efficacy have not been established.

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Heart

Consult your doctor

Limited information available for use of Pegawin Tablet in heart patients. Please consult your doctor.

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Geriatrics

Consult your doctor

Limited information available for use of Pegawin Tablet in elderly patients. Please consult your doctor.

What if I have taken an overdose of Pegawin Tablet

Do not take more than the prescribed dose of Pegawin Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Maintain Stable Blood Sugar Levels: Keep your blood sugar levels stable, as high blood sugar can cause further damage to delicate nerve fibres.
  • Follow a Nutrient-Rich Diet: Incorporate foods rich in whole grains, lean proteins, and leafy green vegetables to naturally support your nervous system.
  • Stay Physically Active: Engage in regular, low-impact physical activities like walking, swimming, or stationary cycling to improve blood circulation to your nerves.
  • Perform Daily Foot Checks: Examine your feet daily for any cuts, blisters, or dry skin, as reduced nerve sensation can make it harder to feel minor injuries.
  • Avoid Alcohol Consumption: Avoid drinking alcohol, as it can worsen nerve damage and increase the sedating side effects of this medication.

Have a query?

How Soon It Starts Working

The time required for Pegawin Tablet to start to work: Pegawin Tablet ideally shows its action within 30 to 60 minutes after administration. The time for which the effects of Pegawin Tablet last: The effect of Pegawin Tablet lasts for 12 to 24 hours.

What if you forget to take Pegawin Tablet

If you forget to take a dose of Pegawin Tablet , take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dose. Do not take a double dose to make up for the missed one.

Storage

•Store Pegawin Tablet at room temperature, ideally between 15°C and 30°C (59°F to 86°F). •Keep the medication in its original packaging to protect it from moisture and direct sunlight. Do not store it in damp areas like the bathroom.

Drug Warnings

  • Do Not Stop the Medication Abruptly: Do not stop taking Pegawin Tablet suddenly, as doing so can cause withdrawal symptoms like anxiety, insomnia, sweating, or a return of your pain; consult your doctor for a plan to gradually decrease your dose.
  • Use Caution When Driving or Operating Machinery: Avoid driving, riding a bicycle, or operating tools and machinery until you know how this medication affects your alertness and balance.
  • Monitor Your Symptoms Regularly: Keep a simple daily log of your pain levels and any side effects to share with your doctor during your regular check-ups.
  • Inform Healthcare Providers About Your Medication: Always inform any healthcare provider you visit, including dentists and surgeons, that you are taking this medication before undergoing any procedures.
  • Elderly Patient Precaution: Older adults may be more sensitive to dizziness, sleepiness, and balance problems. Take extra care when standing up, walking on uneven surfaces, or climbing stairs. 

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Drug-Drug Interactions

Pegawin Tablet may interact with certain medications, potentially increasing side effects or affecting treatment safety. Inform your healthcare provider about all medicines, supplements, and herbal products you are taking:

  • Opioid Pain Relievers and Benzodiazepines: Taking this medication with strong prescription pain relievers (like opioids) or anxiety medications (like benzodiazepines) can cause extreme sleepiness and dangerous breathing difficulties.
  • Certain Blood Pressure Medications: Combining this medicine with certain blood pressure medications (such as ACE inhibitors) may increase the risk of swelling in your limbs or allergic reactions.

Drug-Food Interactions

Certain foods and beverages can influence the safety of this medication and may increase the likelihood of side effects:

  • Alcohol: Alcohol must be avoided because it can severely multiply the dizziness and drowsiness caused by the medication, increasing your risk of falls and injury.

Drug-Disease Interactions

Certain medical conditions may affect how safely this medicine can be used. Make sure your doctor is aware of your complete medical history before starting treatment:

  • Kidney Disease: Pregabalin is primarily removed from the body through the kidneys. Reduced kidney function can cause the medicine to accumulate and increase the risk of side effects. Patients with kidney impairment typically require dose adjustment and closer medical supervision.
  • Heart Problems: It can cause fluid retention, which may worsen symptoms in individuals with congestive heart failure.
  • History of Addiction: Individuals with a history of substance misuse should use this medication with caution due to a risk of dependence.

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Habit Forming

Not enough scientific literature available around this hence it is best to consult your physician

Therapeutic Class

[ANTICONVULSANT]

FAQs

Pegawin Tablet is used to treat neuropathic pain, a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system.

Pegawin Tablet is a combination of five drugs: Pregabalin (anti-convulsant or antiepileptic), methylcobalamin (vitamin B12), benfotiamine (vitamin B1), pyridoxine (vitamin B6) and folic acid (vitamin B9). Pegawin Tablet is used to treat neuropathic pain. Pregabalin affects the chemicals in the brain that send pain signals in the nervous system, thereby relieving nerve pain and lowers the risk of seizures. Methylcobalamin and Pyridoxine help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Benfotiamine and Folic acid help in providing essential nutrients to the nerves. Together, Pegawin Tablet helps in providing relief from neuropathic pain.

No. Do not stop taking Pegawin Tablet suddenly, even if you feel better or your nerve pain has improved. Abrupt discontinuation may lead to withdrawal symptoms such as headache, nausea, anxiety, sleep disturbances, or recurrence of pain. Your doctor may gradually reduce the dose before stopping treatment.

People taking Pegawin Tablet should be closely monitored for suicidal thoughts or behavior. Do not be reluctant to speak with your doctor immediately if you experience suicidal tendencies.

Yes, Pegawin Tablet may cause weight gain in some people. This may occur due to increased appetite, fluid retention, or effects associated with pregabalin therapy. Maintaining a balanced diet and regular physical activity may help manage weight gain.

You can take Pegawin Tablet every day for the duration recommended by your doctor. Avoid excessive doses of Pegawin Tablet to reduce potential effects. However, consult a doctor if you have any concerns.

Pegawin Tablet is good for diabetic neuropathy. Pegawin Tablet contains nutrients which support nerve repair, and reduce nerve pain. However, consult your doctor for proper dosage and to ensure it is for your specific condition.

Yes, Pegawin Tablet contains Vitamin B12 (methylcobalamin), which supports nerve health and is helpful for conditions such as neuropathy.

Yes, Pegawin Tablet may cause sleepiness, drowsiness, or dizziness, especially during the initial stages of treatment or after a dose increase. Avoid driving, operating machinery, or performing tasks that require alertness until you know how the medicine affects you. Consult your doctor if these effects persist or worsen.

Serious side effects of Pegawin Tablet are rare. If you experience symptoms like difficulty breathing, blue-coloured lips, or sleeping disorder, seek medical help immediately. However, if you experience any of these symptoms, please consult your doctor immediately.

Some people may notice improvement in nerve pain within the first 1–2 weeks of treatment, while for others it may take several weeks. The full benefits may take up to 2–3 months to develop. Continue taking Pegawin Tablet as prescribed, even if you do not experience immediate relief.

If you forget to take a dose of Pegawin Tablet , take it as soon as you remember. If it is nearly time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose.

If you accidentally take too much of Pegawin Tablet , seek medical attention immediately.

No, higher than the recommended dose of Pegawin Tablet will not be more effective, instead it can lead to increased side effects. Therefore, do not exceed the recommended dose. If your symptoms worsen, please consult your doctor.

You are advised to avoid alcohol while taking Pegawin Tablet . Alcohol can increase side effects such as dizziness, drowsiness, poor coordination, and impaired concentration. Consult your doctor if you have any concerns about alcohol consumption while using this medicine.

You should see your doctor regularly while taking Pegawin Tablet . If the recommended dosage does not relieve your symptoms or if side effects interfere with your daily activities, please consult your doctor.

Store Pegawin Tablet at a temperature below 25°C in a cool and dry place as advised on the label. Protect from light and moisture. Keep it out of reach of children. Pegawin Tablet should be disposed, by following local guidelines or asking your pharmacist how to properly dispose of any unused medicine.

Pegawin Tablet contains benfotiamine (vitamin B1), folic acid (vitamin B9), methylcobalamin (vitamin B12), pregabalin (anticonvulsant) and pyridoxine (vitamin B6) as its active substances.

Pegawin Tablet is not specifically used to lower blood pressure. If you have high blood pressure, consult a doctor for appropriate medications or treatments.

Pegawin Tablet can be taken with or without food, including on an empty stomach, as advised by your doctor. Take it with a glass of water and preferably at the same time each day to maintain consistent levels in the body. Follow your doctor's instructions carefully.

Pegawin Tablet is generally not recommended during pregnancy unless your doctor decides that the benefits clearly outweigh the potential risks to the unborn baby. If you are pregnant, planning to become pregnant, or are currently breastfeeding, talk to your doctor before using this medicine.

The safety and suitability of this combination medicine in children depend on the child's age, weight, and medical condition. It should only be used in children when specifically prescribed and supervised by a healthcare professional.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Medo House, 25, Puliyur 2Nd Main Rd, Ganga Nagar, Trustpuram, Kodambakkam, Chennai, Tamil Nadu 600024
Other Info - PEG0048
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