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compositionComposition:MEROPENEM-1GM
prescription
Prescription Medicine
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Penmero Injection 1 gm is an antibiotic used to treat severe bacterial infections. It treats bacterial infections of various body parts like skin, soft tissues, blood, brain (meningitis), lungs (pneumonia), urinary tract. It contains Meropenem, which prevents the formation of the bacterial protective cell wall required for bacteria to survive. Thus, it kills the bacteria.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

MEROPENEM-1GM

Manufacturer/Marketer :

Biocon Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Penmero Injection 1 gm

Penmero Injection 1 gm is a prescription antibiotic injection used to treat severe bacterial infections. It is prescribed for serious conditions such as complicated skin infections, severe stomach infections, and bacterial meningitis.

This medicine is usually injected directly into a vein at regular intervals throughout the day to keep a steady level of the drug in your body. Because it is given as an injection or intravenous (IV) infusion, it is typically injected by a healthcare professional in a hospital, clinic, or sometimes at home under strict medical supervision. Getting plenty of rest and drinking enough fluids can support your body's recovery while receiving this treatment.

While taking Penmero Injection 1 gm, you may experience mild side effects such as nausea, headache, or pain where the injection was given. However, if you develop severe diarrhoea, skin rashes, or sudden confusion, you must tell your healthcare provider immediately.

Do not take this if you have had a severe allergic reaction to similar antibiotics, such as penicillins or cephalosporins. It is important to discuss your medical history with your doctor before starting this medicine, especially if you have a history of kidney disease or brain disorders like epilepsy.

This medicine can interact with certain medications, such as valproic acid, which is used for seizures, making it less effective. Always consult your doctor before starting this medicine if you are pregnant, breastfeeding, or managing health conditions as an older adult.

Uses of Penmero Injection 1 gm

Your doctor may prescribe this medicine to treat several conditions, including:

  • Severe stomach infections: Penmero Injection 1 gm helps clear complicated intra-abdominal infections by killing the multiple types of bacteria causing the infection.
  • Bacterial meningitis: It treats serious infections of the membranes covering the brain and spinal cord by penetrating these tissues to eliminate the bacteria.
  • Complicated skin and tissue infections: It targets and destroys deep-seated bacteria in severe skin and soft tissue infections, preventing them from spreading.
  • Severe pneumonia: It helps resolve serious lung infections by stopping the growth of the bacteria responsible for the illness.
     

Key Benefits

Penmero Injection 1 gm provides rapid and effective treatment for serious bacterial infections by delivering powerful antibacterial action when quick infection control is needed. Key benefits include:

  • Rapid Infection Control: By reaching the bloodstream directly, Penmero Injection 1 gm allows the medicine to act quickly against severe bacterial infections, helping limit the spread of infection throughout the body.
  • Broad-Spectrum Bacterial Coverage: By targeting a wide range of bacteria, Penmero Injection 1 gm helps manage complex infections and supports faster recovery when appropriate for the specific infection.
  • Effective Option for Severe Infections: Penmero Injection 1 gm provides a reliable treatment approach for serious infections that may require stronger therapy or have not responded adequately to standard antibiotic treatments.
  • Supports Recovery and Healing: By controlling bacterial growth effectively, Penmero Injection 1 gm helps reduce the impact of infection and supports a smoother recovery process.
     
Side effects of Penmer 1gm Inj
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
  • Stay hydrated by drinking plenty of water to help reduce swelling.
  • Include anti-inflammatory foods like turmeric, ginger, and omega-3 rich foods in your diet.
  • Avoid processed and high-sodium foods that can exacerbate swelling.
  • Utilize an ice pack wrapped in a cloth to cool the affected area, helping to alleviate swelling and discomfort.
  • Gently massage the site, if recommended by your healthcare provider, to promote lymphatic drainage.
  • Rotate injection sites to minimize irritation and swelling.
  • Allow your body time to rest and recuperate, limiting physically demanding tasks to facilitate a smoother recovery.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.

Directions for Use

  • Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.
  • Penmero Injection 1 gm will be administered by a healthcare professional.
  • Do not self-administer.

How Penmero Injection 1 gm Works

Penmero Injection 1 gm contains meropenem, and it belongs to a class of medicines called carbapenem antibiotics. It works by interfering with the ability of bacteria to build their protective outer cell walls. Without a stable cell wall, the bacterial cells lose their structure, rupture, and die, which effectively stops the infection from spreading in your body. Because it is injected directly into your bloodstream, it begins targeting the bacteria immediately, making it highly effective for deep-seated or rapidly progressing infections.
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Alcohol

Caution

Penmero Injection 1 gm can affect alertness and coordination. So, alcohol consumption should be avoided as it might further reduce alertness and cause excessive drowsiness.

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Pregnancy

Caution

Penmero Injection 1 gm is a category B pregnancy drug. It is not known to harm the baby. But it should only be taken if prescribed by a doctor.

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Breast Feeding

Caution

Penmero Injection 1 gm should only be taken in breastfeeding women if prescribed by a doctor.

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Driving

Caution

Penmero Injection 1 gm can affect alertness and coordination. So, operating machinery which requires concentration should be avoided.

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Liver

Caution

Penmero Injection 1 gm to be taken with caution, especially if you have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Caution

Penmero Injection 1 gm to be taken with caution, especially if you have had a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Children

Caution

Penmero Injection 1 gm is generally safe for children aged above 3 months. A doctor should only give it at a hospital.

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Heart

Consult your doctor

Limited information is available; please consult your doctor.

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Geriatrics

Consult your doctor

Limited information available for use of Penmero Injection 1 gm in elderly patients. Please consult your doctor.

What if I have taken an overdose of Penmero Injection 1 gm

Because this medicine is given under medical supervision or in carefully measured doses, an overdose is unlikely. However, if you suspect an overdose or experience severe side effects like seizures, seek emergency medical attention immediately.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water and clear fluids, especially if you experience mild diarrhoea, to prevent dehydration.
  • Support your gut: Consider eating probiotic-rich foods, like yoghurt, or talking to your doctor about taking a probiotic supplement after completing your antibiotic course to help restore healthy gut bacteria.
  • Get plenty of rest: Allow your body to use its energy to fight the infection by avoiding strenuous activities and getting sufficient sleep.
  • Eat balanced meals: Consume simple, easy-to-digest foods if you experience mild nausea during your treatment.
     
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Have a query?

How Soon It Starts Working

The time required for Penmero Injection 1 gm to start to work: The time required for Penmero Injection 1 gm to show its action is clinically unknown. The time for which the effects of Penmero Injection 1 gm last: The duration of action for Penmero Injection 1 gm is clinically unknown.

What if you forget to take Penmero Injection 1 gm

If you miss a dose, contact your healthcare provider or home-health nurse immediately for instructions on when to inject the next dose. Do not inject a double dose to make up for a missed one.

Storage

•Store unopened vials of the dry powder at room temperature, ideally between 20°C and 25°C (68°F to 77°F). Keep them away from excess heat and moisture. •Once the powder is mixed with liquid (reconstituted), it must be used within a specific timeframe.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Check the liquid: Always inspect the mixed solution before use; it should be clear and free of particles. Do not inject it if you see floating particles or if the colour looks unusual.
  • Complete the full course: Even if you begin to feel completely healthy, continue taking the medication for the entire duration prescribed by your doctor to prevent the infection from returning.
  • Practice safe needle hygiene: Use a sterile needle and syringe for every single injection, and never reuse or share needles.
  • Rotate injection sites: If you are receiving injections in different veins, follow your nurse's guidance on rotating sites to prevent vein irritation.
  • Monitor kidney health: Keep all appointments for scheduled blood tests so your doctor can monitor your kidney function and adjust your dose if necessary.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Valproic acid or Divalproex sodium: Penmero Injection 1 gm can significantly lower the levels of these seizure medications in your blood, which may increase your risk of having a seizure.
  • Probenecid: This medication can slow down how quickly your body processes and removes Penmero Injection 1 gm, leading to higher levels of the antibiotic in your blood.
     
MeropenemIomeprol
Severe
MeropenemDivalproex
Severe

Drug-Drug Interactions

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MeropenemIomeprol
Severe
How does the drug interact with Penmer 1gm Inj:
Co-administration of Iomeprol and Penmer 1gm Inj together can increase the risk of causing seizures.

How to manage the interaction:
Taking Penmer 1gm Inj with Iomeprol together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs - close monitoring, seizures, or head injury - contact a doctor right away." Do not stop using any medications without talking to a doctor.
MeropenemDivalproex
Severe
How does the drug interact with Penmer 1gm Inj:
Co-administration of Divalproex and Penmer 1gm Inj can reduce the blood levels of Divalproex sodium.

How to manage the interaction:
Co-administration of Divalproex with Penmer 1gm Inj can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without a doctor's advice.
MeropenemSodium Valproate
Severe
How does the drug interact with Penmer 1gm Inj:
Co-administration of Meropenam and Sodium valproate together can reduce the effect of Sodium valproate.

How to manage the interaction:
Co-administration of Meropenam and Sodium valproate can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
MeropenemMetrizamide
Severe
How does the drug interact with Penmer 1gm Inj:
Co-administration of Metrizamide and Penmer 1gm Inj together can increase the risk of seizures.

How to manage the interaction:
Taking Penmer 1gm Inj with Metrizamide together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs - being closely monitored by your doctor, having seizures, or having a condition or head injury - contact a doctor right away. Do not stop using any medications without a doctor's advice.
MeropenemTramadol
Severe
How does the drug interact with Penmer 1gm Inj:
Taking Tramadol with Penmer 1gm Inj together may cause higher levels of Penmer 1gm Inj in the blood.

How to manage the interaction:
Taking Penmer 1gm Inj with Tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MeropenemBCG vaccine
Severe
How does the drug interact with Penmer 1gm Inj:
When BCG vaccine is used with Penmer 1gm Inj, its effectiveness may be reduced.

How to manage the interaction:
Taking Penmer 1gm Inj with the BCG vaccine together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Penmero Injection 1 gm when used as directed.     
 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBACTERIALS AND ANTIBIOTICS]

FAQs

Penmero Injection 1 gm belongs to a class of drugs known as 'antibiotics', primarily used to treat severe bacterial infections.
Penmero Injection 1 gm is a broad-spectrum antibiotic containing Meropene that works by killing the bacteria (bactericidal in nature). It prevents the formation of a bacterial protective cell wall, which is required for bacteria to survive. And effectively treat bacterial infection.
No, Penmero Injection 1 gm is known to contra-indicate with valproic acid and increase the episodes of seizures. So, both medicines should not be taken together to avoid any unpleasant side effects.
Yes, Penmero Injection 1 gm can cause a serious allergic reaction, including anaphylaxis (serious allergic reaction to a medication), which can be life-threatening. If you have itching, trouble breathing or swallowing, and have swelling in your hands or face, please visit your doctor.
The most common side effects are nausea, vomiting, diarrhea, constipation, headache, pain, redness, pain, or swelling at the injection site. Most of these side effects of Penmero Injection 1 gm do not require medical attention and gradually resolve over time.
Drug resistance is a condition which occurs when the bacteria gets modified in the body and stops reacting to the medicine. As a result, the medicine no longer works. Resistance to Penmero Injection 1 gm is not very common at least for the bacteria against which it works.
Although rare reports indicate that Penmero Injection 1 gm may decrease the blood sugar levels, it does not affect everyone. However, it is important to regularly monitor your blood sugar levels. If you experience any sudden drop in blood sugar levels, consult your doctor.
Penmero Injection 1 gm is generally safe for children above 3 months of age. It is only administered by a doctor at a hospital.
No, do not stop taking Penmero Injection 1 gm without consulting your doctor even if you feel better as it may increase the risk of developing an infection that is resistant to medication. Therefore, complete full course of treatment.
Yes, in some cases, you can inject Penmero Injection 1 gm at home after receiving proper training from a healthcare professional on how to prepare and inject the medication safely. Talk to your doctor to see if home administration is right for you.
Mild diarrhoea can happen, but if you experience severe, watery, or bloody diarrhoea, you should contact your doctor immediately, as this could be a sign of a serious gut infection. Talk to your doctor before taking any anti-diarrhoea medications.
Penmero Injection 1 gm should only be used during pregnancy if clearly needed and prescribed by your doctor. If you are pregnant or planning to become pregnant, talk to your doctor or pharmacist to discuss the benefits and risks.
While there is no direct interaction between Penmero Injection 1 gm and alcohol, it is best to avoid alcohol during your treatment to help your body recover from the infection and prevent additional strain on your liver and kidneys. Talk to your doctor for personalised advice.
In rare cases, Penmero Injection 1 gm can trigger seizures, particularly in individuals who have a pre-existing brain disorder, kidney problems, or are receiving high doses. Talk to your doctor if you have a history of seizures before starting this medicine.
No, Penmero Injection 1 gm is an antibiotic and only works against bacterial infections. It will not treat viral infections such as colds, the flu, or COVID-19. Talk to your doctor if you are unsure about the cause of your infection.
All used needles and syringes must be placed immediately into a puncture-resistant sharps container. Never throw needles in the household trash or recycle bins. Talk to your pharmacist about local guidelines for safe medical waste disposal.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. MedlinePlus. A696038 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. U.S. Food and Drug Administration (FDA). 050706S022Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  4. Drugs.com Clinical Review Team. Meropenem Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  5. Meropenem Meropenem. 1996. [Accessed on 29 Mar. 2019]Check here
  6. Ema.meropenem. [[Accessed on 31 Jul].2019]Check here
  7. Mayoclinic.meropenem. [[Accessed on 31 Jul].2019] Lctmed.meropenem. [[Accessed on 31 Jul].2019] Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Meropenem. [Updated 2018 Oct 31]Check here

Country of origin

India

Manufacturer/Marketer address

20Th Km, Hosur Road, Electronic City, Bangalore, India - 560 100
Other Info - PEN0218
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