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  3. Pentasa Sachet 1 gm

Pentasa Sachet 1 gm, Pack of 1 GRANULES
Pentasa Sachet 1 gm, Pack of 1 GRANULES
Pentasa Sachet 1 gm, Pack of 1 GRANULES
Pentasa Sachet 1 gm, Pack of 1 GRANULES
Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Pentasa Sachet 1 gm is used to treat Ulcerative colitis and Crohn's disease. It contains Mesalazine, an anti-inflammatory drug. It works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. This helps reduce inflammation (redness and swelling) in the intestines and relieves stomach pain or bleeding symptoms. Also, it may prevent further episodes of ulcerative colitis.

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Composition :

MESALAZINE-1GM

Manufacturer/Marketer :

Ferring Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pentasa Sachet 1 gm

Pentasa Sachet 1 gm belongs to a class of drugs called 'anti-inflammatory drugs used to treat ulcerative colitis and Crohn’s disease. Ulcerative colitis is a type of chronic inflammatory bowel disease that causes inflammation of the large intestine lining (colon). It produces ulcers on the colon's lining, which may cause bleeding and discharge of pus and mucus.

Pentasa Sachet 1 gm contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby, it reduces inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.

Take Pentasa Sachet 1 gm as prescribed. You are advised to use Pentasa Sachet 1 gm for as long as your doctor has recommended it for you based on your medical condition. In some cases, you may experience diarrhoea, stomach pain, headache, nausea, vomiting or flatulence (gas). Most of these side effects of Pentasa Sachet 1 gm do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Avoid taking Pentasa Sachet 1 gm if you are allergic to Mesalazine or any other medicines. Pentasa Sachet 1 gm should be used with caution in the elderly. If you are pregnant or breastfeeding, please inform your doctor before taking Pentasa Sachet 1 gm. Avoid taking Pentasa Sachet 1 gm if you have severe kidney failure. If you have stomach pain or cramps, severe headache, fever or rash, stop taking Pentasa Sachet 1 gm immediately and consult a doctor.

Uses of Pentasa Sachet 1 gm

Pentasa Sachet 1 gm is used to treat Ulcerative colitis and Crohn's disease

Directions for Use

Check the label for directions and use as advised by the doctor. Empty the contents directly on the tongue and drink some water or orange juice. They can also be mixed with yoghurt and should be taken immediately without chewing.

Medicinal Benefits

Pentasa Sachet 1 gm contains Mesalazine, an anti-inflammatory drug used in the treatment of ulcerative colitis and Crohn’s disease. It works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helping in reducing inflammation (redness and swelling) in the intestines and providing relief from symptoms such as stomach pain or bleeding. Also, Pentasa Sachet 1 gm may prevent further episodes of ulcerative colitis.

Storage

Store in a cool and dry place away from sunlight
Side effects of Pentasa Sachet 1 gm
  • Eating and drinking slowly can help swallow less air, which reduces burps.
  • Avoid consuming foods like gum and hard candy and drinking carbonated drinks as they release carbon dioxide gas in your body.
  • Prevent smoking as it can impact your whole body.
  • Seek medical help to treat gastric problems and heart burn that may lead to frequent burps.
  • Check your dentures because if they are loosely fit, excess air can be swallowed that causes burbs more frequently.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Get ample rest; this helps your stomach to settle.
  • Eat soft and easy-to-digest foods like white rice, bananas, crackers and apple sauce.
  • Include probiotics-rich food like yoghurt, kefir, or miso, as they help maintain gut functioning.
  • Wash your hands properly before preparing/eating food and after using the toilet.
  • Drink water, broth or diluted fruit juice to replace electrolytes and lost fluids.
  • Avoid caffeine, alcohol, high-fat, fried and fast foods, as well as sweetened beverages.

What if I have taken an overdose of Pentasa Sachet 1 gm

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Pentasa Sachet 1 gm may include nausea, vomiting, abdominal pain, fast or shallow breathing, ringing in the ears, headache, dizziness, confusion, and seizures. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

If you are allergic to Mesalazine or any other medicines, please tell your doctor. Pentasa Sachet 1 gm should be used with caution in the elderly. If you are pregnant or breastfeeding, please inform your doctor before taking Pentasa Sachet 1 gm. Avoid taking Pentasa Sachet 1 gm if you have severe kidney failure. Severe skin reactions such as toxic epidermal necrolysis (skin peeling and blistering) or Stevens-Johnson syndrome (a painful rash that spreads and blisters) can occur in some patients taking Pentasa Sachet 1 gm. Therefore, if you notice any skin reactions while taking Pentasa Sachet 1 gm, please consult a doctor immediately. If you have stomach pain or cramps, severe headache, fever or rash, stop taking Pentasa Sachet 1 gm immediately and consult a doctor. Avoid taking Pentasa Sachet 1 gm if you have had blood abnormalities or kidney problems while taking other medicines such as Sulphasalazine.

Drug-Drug Interactions

verifiedApollotooltip
MesalazineCidofovir
Critical
MesalazineMetrizamide
Severe

Drug-Drug Interactions

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MesalazineCidofovir
Critical
How does the drug interact with Pentasa Sachet 1 gm:
Co-administration of Pentasa Sachet 1 gm with Cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Pentasa Sachet 1 gm with Cidofovir is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience increased or decreased urination, sudden weight gain or loss, shortness of breath, consult a doctor. Do not discontinue any medications without consulting a doctor.
MesalazineMetrizamide
Severe
How does the drug interact with Pentasa Sachet 1 gm:
Co-administration of Metrizamide with Pentasa Sachet 1 gm may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Pentasa Sachet 1 gm with Metrizamide they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, dry, itchy skin, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
MesalazineNizatidine
Severe
How does the drug interact with Pentasa Sachet 1 gm:
Co-administration of Nizatidine with Pentasa Sachet 1 gm can decrease the level or effect of Mesalamine by increasing gastric pH.

How to manage the interaction:
Although there may be a possible interaction between Pentasa Sachet 1 gm with Nizatidine, they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineRanitidine
Severe
How does the drug interact with Pentasa Sachet 1 gm:
Co-administration of Ranitidine with Pentasa Sachet 1 gm can decrease the levels of Pentasa Sachet 1 gm, which may be less effective in treating a condition.

How to manage the interaction:
There may be a possible interaction between Pentasa Sachet 1 gm with Ranitidine, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineOmeprazole
Severe
How does the drug interact with Pentasa Sachet 1 gm:
Co-administration of omeprazole with Pentasa Sachet 1 gm can decrease the effects of Pentasa Sachet 1 gm.

How to manage the interaction:
There could be a possible interaction between Pentasa Sachet 1 gm and omeprazole, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineTenofovir alafenamide
Severe
How does the drug interact with Pentasa Sachet 1 gm:
Co-administration of Tenofovir alafenamide with Pentasa Sachet 1 gm may increase the risk of kidney problems.

How to manage the interaction:
There is a possibility of interaction between Pentasa Sachet 1 gm with Tenofovir alafenamide, but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience increased or decreased urination, swelling, shortness of breath, bone pain, cramping in the muscles. Do not discontinue the medication without consulting a doctor.
MesalazineDeferasirox
Severe
How does the drug interact with Pentasa Sachet 1 gm:
Co-administration of Deferasirox with Pentasa Sachet 1 gm may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possibility of interaction between Pentasa Sachet 1 gm and Deferasirox but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as increased or decreased urination, abrupt weight gain or loss, weakness, or dizziness. Do not discontinue the medication without consulting a doctor.
MesalazineIodamide
Severe
How does the drug interact with Pentasa Sachet 1 gm:
Co-administration of Iodamide with Pentasa Sachet 1 gm may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Mesalamine with Iodamine they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, itchy skin, shortness of breath, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
MesalazineIomeprol
Severe
How does the drug interact with Pentasa Sachet 1 gm:
Co-administration of Iomeprol with Pentasa Sachet 1 gm may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Pentasa Sachet 1 gm and Iomeprol they can be taken together if your doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a low-fat diet and eat foods rich in vitamin C, such as bell peppers, spinach, parsley and berries, which help in healing faster.
  • Include olive oil and omega-3 fatty acids. Eat more fibre-rich foods such as fruits and vegetables.
  • Limit dairy intake as your body may develop difficulty digesting certain dairy products when you are affected with Crohn’s disease, which leads to stomach cramps, diarrhoea or stomach upset.
  • Drink plenty of water to prevent dehydration.

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Pentasa Sachet 1 gm Substitute

Substitutes safety advice

  • Pentasa 1gm Enema 100 ml

    by AYUR

    ₹2.52per tablet

  • Rowasa Sachet 1 gm

    by Others

    ₹70.70per tablet

  • Mesalo Foam (Enema) 82 gm

    by Others

    ₹22.34per tablet

  • Rowasa Pellets 1 gm

    by Others

    ₹71.50per tablet

  • Mesarem Pellets 1 gm

    by Others

    ₹43.20per tablet

Product Substitutes

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Alcohol

Caution

The interaction of alcohol with Pentasa Sachet 1 gm is unknown. If you have concerns, please discuss them with your doctor before taking Pentasa Sachet 1 gm.

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Pregnancy

Consult your doctor

Pentasa Sachet 1 gm is a Category B pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks. Please consult your doctor if you are pregnant or planning for pregnancy before taking Pentasa Sachet 1 gm.

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Breast Feeding

Caution

Pentasa Sachet 1 gm should not be taken by breastfeeding mothers unless advised by the doctor. Granules form of Mesalazine may cause allergic reactions such as diarrhoea in newborn babies after breastfeeding. If this happens, discontinue breastfeeding.

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Driving

Safe

Pentasa Sachet 1 gm usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Please consult your doctor, if you have liver problems before using Pentasa Sachet 1 gm.

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Kidney

Caution

Pentasa Sachet 1 gm should be used with extreme caution in patients with mild to moderate kidney impairment. Avoid taking Pentasa Sachet 1 gm if you have severe kidney impairment.

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Children

Caution

Pentasa Sachet 1 gm is not recommended for children below six years. However, Pentasa Sachet 1 gm should be given to children only if recommended by a doctor.

Have a query?

FAQs

Pentasa Sachet 1 gm is used to treat Ulcerative colitis and Crohn's disease.

Pentasa Sachet 1 gm contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helps in reducing inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.

You are not recommended to take Pentasa Sachet 1 gm with Ibuprofen as co-administration of these two medicines may increase the risk of kidney problems. However, please consult your doctor before taking Pentasa Sachet 1 gm with other medicines.

Yes, Pentasa Sachet 1 gm may cause kidney stones in some patients. It is not necessary for everyone taking Pentasa Sachet 1 gm to experience this side effect. However, if you notice blood in urine or pain in the sides of the stomach, please consult a doctor immediately. Drink adequate water while taking Pentasa Sachet 1 gm to prevent kidney stones.

Pentasa Sachet 1 gm should be used with caution in patients with stomach ulcers as it may increase the risk of worsening the condition. Therefore, please inform your doctor if you have a stomach ulcer before taking Pentasa Sachet 1 gm.

Yes, Pentasa Sachet 1 gm may cause diarrhoea as a common side effect. However, if the condition persists and worsens with fever, watery stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking Pentasa Sachet 1 gm to prevent dehydration.

You are advised to take Pentasa Sachet 1 gm for the duration prescribed by the doctor. Talk to the doctor if you have any concerns.

Do not discontinue Pentasa Sachet 1 gm without consulting your doctor. It is essential to keep taking your medicine even if you feel well as it helps control your condition.

No, Pentasa Sachet 1 gm is not addictive.

Side effects of Pentasa Sachet 1 gm include diarrhoea, stomach pain, headache, nausea, vomiting or flatulence (gas). If the side effects persist or worsen, please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

K-28/1, ADDITIONAL MIDC , ANAND NAGAR , AMBERNATH - 421506 , INDIA
Other Info - PEN0166

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Apr 29, 2025 | 10:56 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.2217.pdf
  2. https://www.medicines.org.uk/emc/files/pil.1291.pdf
  3. https://www.drugs.com/mtm/mesalamine.html
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