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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Mesarect 1G Suppositories 2x7's is used to treat ulcerative colitis. It contains Mesalazine, which helps reduce inflammation (redness and swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding. It may cause side effects such as diarrhoea, stomach pain, headache or nausea.

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Composition :

MESALAZINE-1GM

Manufacturer/Marketer :

Meridian Enterprises Pvt Ltd

Consume Type :

RECTAL

Return Policy :

Not Returnable

Expires on or after :

About Mesarect 1G Suppositories 2x7's

Mesarect 1G Suppositories 2x7's is used to treat ulcerative colitis and ulcerative proctitis. Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation of the large intestine lining (colon). Ulcerative proctitis is a condition in which ulcerative colitis solely affects the rectum.

Mesarect 1G Suppositories 2x7's contains Mesalazine, which works by preventing the synthesis of chemical messengers such as prostaglandins in the intestines that produce inflammation (swelling).

Sometimes, you may experience diarrhoea, stomach pain, headache or nausea. Most of these side effects of Mesarect 1G Suppositories 2x7's do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

Follow your doctor's instructions on the dosage and timing of this medication. Mesarect 1G Suppositories 2x7's is for rectal use only. It is advised to wash your hands before and after applying the medicament. Ensure the rectal area is clean and dry before application.

Inform your doctor if you are allergic to any components present in Mesarect 1G Suppositories 2x7's. Mesarect 1G Suppositories 2x7's should be used with caution in the elderly. If you are pregnant or breastfeeding, please inform your doctor before taking Mesarect 1G Suppositories 2x7's. Avoid taking Mesarect 1G Suppositories 2x7's if you have severe kidney failure. If you have stomach pain, cramps, severe headache, fever or rash, after taking Mesarect 1G Suppositories 2x7's, stop taking it immediately and consult a doctor.

Uses of Mesarect 1G Suppositories 2x7's

Mesarect 1G Suppositories 2x7's is used in the treatment of Ulcerative colitis and Ulcerative proctitis. The detailed uses of Mesarect 1G Suppositories 2x7's are as follows:

  • Management of Irritable Bowel Syndrome (IBS): Mesarect 1G Suppositories 2x7's helps manage IBS symptoms like bloating, gas, and abdominal discomfort.
  • Support for Ulcerative Colitis: Mesarect 1G Suppositories 2x7's supports ulcerative colitis management by reducing flare-ups and promoting gut health.
  • Restoration of Gut Flora Post-Antibiotics: Mesarect 1G Suppositories 2x7's helps to restore beneficial gut bacteria after antibiotic use.

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Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Check the label for directions and use it as advised by the doctor. 
  • Before using, empty your bowels (if necessary) and wash your hands. Shake the bottle vigorously for at least 30 seconds. Remove the applicator's protective cap and hold the bottle by its top end. Lie on your left side, your left leg extended and your right leg bent. Insert the applicator (lubricant-coated) for easier entry into the rectum. Squeeze the bottle gently while holding it directed towards your navel. When the bottle is empty, remove the applicator from the rectum. Allow the drug to spread throughout the lower section of the large intestine for at least 30 minutes by remaining in this posture.
  • Wash your hands before and after applying the medicament. Ensure the rectal area is clean and dry before application.
  • For rectal use only.

Medicinal Benefits

  • Mesarect 1G Suppositories 2x7's contains Mesalamine, an anti-inflammatory drug used to treat ulcerative colitis and ulcerative proctitis.
  • This medicine helps reduce inflammation (redness and swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.
  • Mesarect 1G Suppositories 2x7's may also prevent further episodes of ulcerative colitis.

How Mesarect 1G Suppositories 2x7's Works

Mesarect 1G Suppositories 2x7's contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thus, it helps reduce inflammation (redness and swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Mesarect 1G Suppositories 2x7's
  • Eating and drinking slowly can help swallow less air, which reduces burps.
  • Avoid consuming foods like gum and hard candy and drinking carbonated drinks as they release carbon dioxide gas in your body.
  • Prevent smoking as it can impact your whole body.
  • Seek medical help to treat gastric problems and heart burn that may lead to frequent burps.
  • Check your dentures because if they are loosely fit, excess air can be swallowed that causes burbs more frequently.
  • If you have bowel inflammation, eat smaller quantities and more frequent meals.
  • Eat slowly and chew your food thoroughly to help digestion.
  • Eat fiber-rich foods such as fruits, whole grains, and vegetables to promote regular bowel movements.
  • Avoid gas-producing foods like cabbage, beans, broccoli and carbonated drinks.
  • Drink lots of water throughout the day to prevent dehydration and aid digestion.
  • Do regular exercise to enhance digestion and reduce bloating.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

What if I have taken an overdose of Mesarect 1G Suppositories 2x7's

Do not use Mesarect 1G Suppositories 2x7's in more doses or more often than prescribed. If you have any unusual signs or symptoms, please consult a doctor immediately.

Drug Warnings

  • Inform your doctor if you are allergic to this medication or any of its components.
  • The use of Mesarect 1G Suppositories 2x7's should be exercised with caution in the elderly.
  • Avoid taking Mesarect 1G Suppositories 2x7's if you have severe kidney failure.
  • Do not use Mesarect 1G Suppositories 2x7's if you are pregnant, planning to become pregnant, or breastfeeding without first consulting the doctor.
  • Mesarect 1G Suppositories 2x7's is recommended not to be used in populations with severe renal or hepatic impairment, so inform your doctor if you have severe renal or hepatic impairment.
  • Use Mesarect 1G Suppositories 2x7's as directed by a doctor, in the dose and duration advised.
  • Mesarect 1G Suppositories 2x7's is for rectal use. Do not swallow it. In case of accidental swallowing, drink plenty of water and consult a doctor immediately.
  • Mesarect 1G Suppositories 2x7's is not recommended for use in children.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Mesarect 1G Suppositories 2x7's:
Co-administration of Mesarect 1G Suppositories 2x7's with Cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Mesarect 1G Suppositories 2x7's with Cidofovir is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience increased or decreased urination, sudden weight gain or loss, shortness of breath, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mesarect 1G Suppositories 2x7's:
Co-administration of omeprazole with Mesarect 1G Suppositories 2x7's can decrease the effects of Mesarect 1G Suppositories 2x7's.

How to manage the interaction:
There could be a possible interaction between Mesarect 1G Suppositories 2x7's and omeprazole, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mesarect 1G Suppositories 2x7's:
Co-administration of Tenofovir alafenamide with Mesarect 1G Suppositories 2x7's may increase the risk of kidney problems.

How to manage the interaction:
There is a possibility of interaction between Mesarect 1G Suppositories 2x7's with Tenofovir alafenamide, but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience increased or decreased urination, swelling, shortness of breath, bone pain, cramping in the muscles. Do not discontinue the medication without consulting a doctor.
MesalazineIodamide
Severe
How does the drug interact with Mesarect 1G Suppositories 2x7's:
Co-administration of Iodamide with Mesarect 1G Suppositories 2x7's may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Mesalamine with Iodamine they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, itchy skin, shortness of breath, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Mesarect 1G Suppositories 2x7's:
Co-administration of Ranitidine with Mesarect 1G Suppositories 2x7's can decrease the levels of Mesarect 1G Suppositories 2x7's, which may be less effective in treating a condition.

How to manage the interaction:
There may be a possible interaction between Mesarect 1G Suppositories 2x7's with Ranitidine, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineIomeprol
Severe
How does the drug interact with Mesarect 1G Suppositories 2x7's:
Co-administration of Iomeprol with Mesarect 1G Suppositories 2x7's may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Mesarect 1G Suppositories 2x7's and Iomeprol they can be taken together if your doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
MesalazineMetrizamide
Severe
How does the drug interact with Mesarect 1G Suppositories 2x7's:
Co-administration of Metrizamide with Mesarect 1G Suppositories 2x7's may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Mesarect 1G Suppositories 2x7's with Metrizamide they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, dry, itchy skin, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
MesalazineNizatidine
Severe
How does the drug interact with Mesarect 1G Suppositories 2x7's:
Co-administration of Nizatidine with Mesarect 1G Suppositories 2x7's can decrease the level or effect of Mesalamine by increasing gastric pH.

How to manage the interaction:
Although there may be a possible interaction between Mesarect 1G Suppositories 2x7's with Nizatidine, they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mesarect 1G Suppositories 2x7's:
Co-administration of Deferasirox with Mesarect 1G Suppositories 2x7's may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possibility of interaction between Mesarect 1G Suppositories 2x7's and Deferasirox but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as increased or decreased urination, abrupt weight gain or loss, weakness, or dizziness. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a low-fat diet and eat foods rich in vitamin C, such as bell peppers, spinach, parsley, and berries, which help promote faster healing.
  • Opt for food and drinks rich in Omega-3 fatty acids to alleviate pain, swelling, and inflammation. Omega 3 fatty acid-enriched foods include flaxseeds, walnuts, soybean oil, salmon, and tuna if you prefer non-veg.
  • Eat more fibre-rich foods such as fruits and vegetables.
  • Eat smaller meals all day.
  • Drink small amounts of water throughout the day.
  • If you are intolerant to lactose, lower your intake of milk.
  • Avoid consuming foods high in sugar and fat, as well as processed foods, as these may trigger inflammation.
  • Try to avoid alcohol as it can affect your stomach and intestines and also limit the absorption of the important nutrients required by your body.

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

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Alcohol

Consult your doctor

The interaction of alcohol with Mesarect 1G Suppositories 2x7's is unknown. Consult the physician.

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Pregnancy

Unsafe

Mesarect 1G Suppositories 2x7's should not be used in pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy.

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Breast Feeding

Consult your doctor

Mesarect 1G Suppositories 2x7's should not be used while breastfeeding unless necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Mesarect 1G Suppositories 2x7's.

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Driving

Safe if prescribed

Mesarect 1G Suppositories 2x7's usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Inform your doctor before using Mesarect 1G Suppositories 2x7's if you have a history of liver disease. It should be used cautiously in patients with mild to moderately impaired liver function. It is not recommended for use in populations with severe liver impairment.

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Kidney

Caution

Inform your doctor before using Mesarect 1G Suppositories 2x7's if you have a history of kidney disease. It should be used cautiously in patients with mild to moderate kidney impairment. It is not recommended for use in populations with severe kidney impairment.

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Children

Not applicable

Mesarect 1G Suppositories 2x7's is intended for adults. Not recommended for children.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems

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Geriatrics

Consult your doctor

Limited information available for use of Mesarect 1G Suppositories 2x7's in elderly patients. Please consult your doctor.

FAQs

Mesarect 1G Suppositories 2x7's is used to treat ulcerative colitis, a chronic inflammatory bowel disease that causes inflammation of the large intestine lining (colon).

Mesarect 1G Suppositories 2x7's contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thus, it helps reduce inflammation (swelling) in the intestines and relieves symptoms such as stomach pain or bleeding.

Mesarect 1G Suppositories 2x7's may cause diarrhoea as a common side effect. However, if the condition persists or worsens, accompanied by fever, watery stools, or persistent stomach pain, please consult a doctor. Also, drink plenty of water while using Mesarect 1G Suppositories 2x7's to prevent dehydration.

You are not recommended to take Mesarect 1G Suppositories 2x7's with aspirin as co-administration of these two medicines may increase the risk of kidney problems. However, please consult your doctor before taking Mesarect 1G Suppositories 2x7's with other medicines.

No, you are not recommended to stop using Mesarect 1G Suppositories 2x7's suddenly, as it may cause recurring symptoms. Therefore, use Mesarect 1G Suppositories 2x7's for as long as your doctor has prescribed it, and if you experience any difficulty while using Mesarect 1G Suppositories 2x7's, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

1108, Embassy Centre, Nariman Point, Mumbai 400 021. India.
Other Info - MES0147

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