Periclin 600 Injection 4 ml
MRP ₹370
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About Periclin 600 Injection 4 ml
Periclin 600 Injection 4 ml is primarily used to treat serious bacterial infections such as lower respiratory tract infections like pneumonia, empyema, and lung abscess; gynecological infections like endometritis, nongonococcal tubo-ovarian abscess, pelvic cellulitis, and postsurgical vaginal cuff infection; intra-abdominal infections; septicaemia or sepsis (blood poisoning by bacteria); and bone and joint infections.
Periclin 600 Injection 4 ml contains 'Clindamycin' that works by preventing bacterial protein synthesis, leading to the inhibition of bacterial growth. It exhibits a bacteriostatic effect, which prevents bacterial reproduction.
Common side effects of Periclin 600 Injection 4 ml include stomach pain, nausea, vomiting, diarrhoea, heartburn, skin rash, pain and swelling at the injection site, and vaginal itching or discharge. Most of these side effects do not require medical attention. If these side effects persist longer, please consult your doctor.
Brief your medical history to the doctor if you are allergic to any of the components in Periclin 600 Injection 4 ml. Let your doctor know if you have any liver disease, kidney disease, yellow food dye allergy, colitis, severe stomach cramps, diarrhoea, and allergic conditions. Do not use Periclin 600 Injection 4 ml while getting vaccinated with live bacterial vaccines (typhoid vaccine) since Periclin 600 Injection 4 ml may affect the vaccine's activity. Periclin 600 Injection 4 ml should be used only with a doctor's advice during pregnancy and breastfeeding.
Uses of Periclin 600 Injection 4 ml
Periclin 600 Injection 4 ml is used in the treatment of bacterial infections. The detailed uses of Periclin 600 Injection 4 ml are as follows:
- Lower respiratory tract infections: Periclin 600 Injection 4 ml is used to treat lung infections, such as pneumonia, empyema, and lung abscess.
- Gynaecological infections: Periclin 600 Injection 4 ml is effective in treating infections such as endometritis, tubo-ovarian abscess (non-gonococcal), pelvic cellulitis, and post-surgical vaginal cuff infections.
- Treatment of intra-abdominal infections: Periclin 600 Injection 4 ml is used to treat infections in the abdominal cavity, such as peritonitis and abscesses.
- Septicemia (sepsis): Periclin 600 Injection 4 ml is used to treat bloodstream infections caused by bacteria that are susceptible to it.
- Treatment of bone and joint infections: Periclin 600 Injection 4 ml is effective in treating osteomyelitis and septic arthritis caused by bacteria.
- Alternative in penicillin-allergic patients: Periclin 600 Injection 4 ml is an antibiotic that can be used instead of penicillin, particularly in anaerobic and gram-positive infections.
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Directions for Use
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
- Periclin 600 Injection 4 ml will be administered by the doctor or healthcare professional.
- Do not self-administer.
Medicinal Benefits
- Periclin 600 Injection 4 ml is an antibiotic that treats severe/serious bacterial infections.
- It works by inhibiting bacterial protein synthesis, which inhibits bacterial growth.
- It shows a bacteriostatic effect, which stops bacterial reproduction but doesn't kill them.
- Periclin 600 Injection 4 ml effectively treats infections caused by gram-positive and anaerobic (living without air) bacteria, including susceptible strains of Staphylococcus aureus, Streptococcus pneumoniae, and Clostridium perfringens.
- Periclin 600 Injection 4 ml is useful in treating lower respiratory tract infections, such as pneumonia, empyema, and lung abscess; gynaecological infections, including endometritis, nongonococcal tubo-ovarian abscess, pelvic cellulitis, and post-surgical vaginal cuff infection; intra-abdominal infections; septicaemia or sepsis (blood poisoning by bacteria); and bone and joint infections.
How Periclin 600 Injection 4 ml Works
Storage
- Take cold water baths avoiding soap.
- Avoid scratching and scrubbing to prevent infections while itching.
- Use nets to prevent insects and mosquitoes.
- Stop using lotions and creams that cause irritation.
- Avoid alcohol and caffeine intake.
- Abnormal liver function requires immediate medical attention. Your doctor may recommend lifestyle modifications along with needed medication.
- Avoid intake of alcohol as it has a direct impact on liver functioning.
- Prevent medications like paracetamol, over-the-counter painkillers or those mentioned by your doctor, as they may have issues getting metabolised in your body.
- If you have overweight issues, losing weight can be a good thing to manage abnormal liver function.
- Cut down the number of fatty foods that are taken daily.
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
- Drink water or other clear fluids.
- To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
- Include bland foods like rice, toast, crackers, and rice in your diet.
- Avoid lying down immediately after eating as it may cause indigestion or heartburn.
- Avoid acidic and spicy food as it may cause indigestion.
- If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
- Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
- As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
- Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
- Take regular breaks to sit or lie down if you need to stand for long periods.
- When lying down, elevate your head with extra pillows to help improve blood flow.
- Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
- Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
- If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
What if I have taken an overdose of Periclin 600 Injection 4 ml
Drug Warnings
- Do not use Periclin 600 Injection 4 ml if you are allergic to any of its components.
- Let your doctor know if you have any liver or kidney diseases, gastrointestinal diseases (colitis, Clostridium difficile-associated diarrhoea), yellow food dye allergy, and allergic conditions (asthma, hay fever, eczema).
- Do not use Periclin 600 Injection 4 ml while getting vaccinated with live bacterial vaccines (typhoid vaccine) since Periclin 600 Injection 4 ml may affect the vaccine's activity.
- Pregnant and breastfeeding women should consult their doctor before taking Periclin 600 Injection 4 ml.
- Avoid alcohol consumption to prevent any undesired effects while using Periclin 600 Injection 4 ml.
Drug-Drug Interactions
Drug-Drug Interactions
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Concomitant use of Periclin 600 Injection 4 ml with ceritinib can increase the effects of Periclin 600 Injection 4 ml
How to manage the interaction:
Although there is a possible interaction, Periclin 600 Injection 4 ml can be taken with ceritinib if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhoea.
Co-administration of Periclin 600 Injection 4 ml may reduce the activity of the cholera vaccine.
How to manage the interaction:
Talk to your doctor before receiving the Cholera vaccine if you are currently being treated with Periclin 600 Injection 4 ml or have been treated within the last 14 days. To ensure adequate vaccine response, you should not receive cholera vaccine until at least 14 days after you complete antibiotic therapy. Do not discontinue the medication without consulting a doctor.
Co-administration of Carbamazepine and Periclin 600 Injection 4 ml together may result in reduced blood levels of Periclin 600 Injection 4 ml, which could make it less effective in treating your disease.
How to manage the interaction:
Although taking carbamazepine and Periclin 600 Injection 4 ml together can possibly result in an interaction, it can be taken if a doctor has prescribed it. If you experience any symptoms like fever, it is advised to consult a doctor. Without consulting a doctor, never stop taking any medications.
Concomitant use of Periclin 600 Injection 4 ml with indinavir may increase the effects of Periclin 600 Injection 4 ml.
How to manage the interaction:
Although there is a possible interaction, Periclin 600 Injection 4 ml can be taken with indinavir if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhoea.
Coadministration of use of Periclin 600 Injection 4 ml with ketoconazole can increase the effects of Periclin 600 Injection 4 ml.
How to manage the interaction:
Although there is a possible interaction, Periclin 600 Injection 4 ml can be taken with ketoconazole if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain or diarrhea. Do not discontinue any medication without consulting a doctor. Do not discontinue any medication without consulting a doctor.
Co-administration of Amprenavir together with Periclin 600 Injection 4 ml can increase the effects of Periclin 600 Injection 4 ml.
How to manage the interaction:
Co-administration of Periclin 600 Injection 4 ml with Amprenavir can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have ongoing feelings of sickness, throwing up, having loose stools, or pain in your stomach, it's important to contact your doctor right away. Do not stop using any medications without talking to a doctor.
Co-administration of Periclin 600 Injection 4 ml with Atazanavir may increase the effects of Periclin 600 Injection 4 ml.
How to manage the interaction:
Although there is a possible interaction, Periclin 600 Injection 4 ml can be taken with atazanavir if prescribed by the doctor. Consult the prescriber if you experience persistent nausea, vomiting, diarrhea, or abdominal pain. Do not discontinue the medication without consulting a doctor.
Taking Periclin 600 Injection 4 ml with Botulinum toxin can increase the risk or severity of side effects.
How to manage the interaction:
Taking Periclin 600 Injection 4 ml with Botulinum toxin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Concomitant use of Periclin 600 Injection 4 ml with itraconazole can reduce the metabolism and increase the levels of Periclin 600 Injection 4 ml in the body. This may increase the risk or severity of side effects.
How to manage the interaction:
Although there is a possible interaction, Periclin 600 Injection 4 ml can be taken with itraconazole if prescribed by the doctor. Consult a doctor immediately if you experience persistent vomiting, nausea, abdominal pain, or diarrhea. Do not stop using any medications without first talking to your doctor.
Co-administration of of Periclin 600 Injection 4 ml with gentamicin may increase the risk of kidney and/or nerve damage.
How to manage the interaction:
Although there is a possible interaction, Periclin 600 Injection 4 ml can be taken with gentamicin if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of kidney damage such as sudden weight gain or weight loss, nausea, vomiting, fluid retention, loss of appetite, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. If you develop diarrhea or vomiting during treatment with these medications, drink plenty of fluids to prevent dehydration, as dehydration may also harm the kidney.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Wash your hands often to maintain cleanliness.
- Avoid sharing personal items like shaving razors.
- Include whole-grain foods, such as multigrain bread and brown rice, in your diet.
- Taking probiotics after an antibiotic treatment reduces the risk of antibiotic-associated diarrhoea.
- Try taking yoghurt, cheese, sauerkraut, and kimchi, which help restore the intestine's good bacteria.
- Include more fibre-enriched food in your diet that is easily digested by your gut bacteria. Fibre foods may also help restore healthy gut bacteria after a course of antibiotics.
- Avoid the intake of alcoholic beverages as it may cause dehydration and affect your sleep.
- Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
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Alcohol
Unsafe
Avoid taking alcohol while using Periclin 600 Injection 4 ml since it may worsen the side effects.
Pregnancy
Consult your doctor
Please consult your doctor before receiving Periclin 600 Injection 4 ml if you are pregnant or planning to conceive.
Breast Feeding
Consult your doctor
Periclin 600 Injection 4 ml can be excreted into breast milk when used by a nursing mother. Please consult your doctor before receiving Periclin 600 Injection 4 ml if you are breastfeeding.
Driving
Consult your doctor
There is limited data on how Periclin 600 Injection 4 ml affects your driving ability. Please seek medical advice for more information.
Liver
Consult your doctor
Let your doctor know if you have any history of liver diseases before receiving Periclin 600 Injection 4 ml since it may cause jaundice and abnormal liver function tests.
Kidney
Consult your doctor
Let your doctor know if you have any history of kidney diseases before receiving Periclin 600 Injection 4 ml.
Children
Consult your doctor
Periclin 600 Injection 4 ml should be used in children only when prescribed by a doctor. Your doctor will prescribe Periclin 600 Injection 4 ml depending on the child's age and body weight.
Heart
Let your doctor know if you have any history of heart disease before starting Periclin 600 Injection 4 ml.
Geriatrics
Consult your doctor
Limited information available about the use of Periclin 600 Injection 4 ml in geriatric patients. Please consult your physician.
FAQs
Periclin 600 Injection 4 ml belongs to the class of antibiotics primarily used to treat serious bacterial infections such as lower respiratory tract infections like pneumonia, empyema, and lung abscess; gynaecological infections like endometritis, nongonococcal tubo-ovarian abscess, pelvic cellulitis, and postsurgical vaginal cuff infection; intra-abdominal infections; septicaemia or sepsis (blood poisoning by bacteria), and bone and joint infections.
Periclin 600 Injection 4 ml is an antibiotic that treats bacterial infections. It works by inhibiting bacterial protein synthesis, which retards bacterial growth.
Periclin 600 Injection 4 ml should be used with proper caution and under the guidance of a doctor if you have any liver disease, kidney disease, gastrointestinal diseases (such as colitis, severe stomach cramps, or diarrhoea), a yellow food dye allergy, or allergic conditions (such as asthma, hay fever, or eczema).
Periclin 600 Injection 4 ml can affect the live vaccines like typhoid vaccine and decrease its effectiveness. Please consult a doctor before you start Periclin 600 Injection 4 ml if you are undergoing any vaccinations.
Periclin 600 Injection 4 ml may cause abnormal liver function tests as a side effect. Please ask your doctor before starting Periclin 600 Injection 4 ml if you have any history of liver problems.
Diarrhoea can be a side-effect of Periclin 600 Injection 4 ml. Clostridium difficile-associated diarrhoea (CDAD) is also reported during usage of antibiotics like Periclin 600 Injection 4 ml. Therefore, if you experience diarrhoea, you are advised to undergo an examination to rule out the chances of CDAD following Periclin 600 Injection 4 ml therapy.
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Reference
- https://www.webmd.com/drugs/2/drug-931/clindamycin-injection/details
- https://www.drugs.com/clindamycin.html#side-effects
- https://www.hpra.ie/img/uploaded/swedocuments/2132447.PPA1151_156_001.68048af4-da55-4413-9a20-e6d58b4c2edd.000001Clindamycin%20leaflet.140204.pdf
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/050441s055,050639s016lbl.pdf
