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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
PERISET INJECTION 2ML is an antiemetic medication used in the treatmnet and prevention of nausea and vomiting during chemotherapy. This medication contains ondansetron which functions by inhibiting the activity of serotonin, a neurotransmitter that activates the brain's vomiting center (chemoreceptor trigger zone, or CTZ).
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Whats That

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Composition :

ONDANSETRON-2MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About PERISET INJECTION 2ML

PERISET INJECTION 2ML is an antiemetic used to prevent and treat nausea and vomiting during chemotherapy. Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

PERISET INJECTION 2ML contains Ondansetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting. 

PERISET INJECTION 2ML will be administered by a healthcare professional. Do not self-administer. In some cases, PERISET INJECTION 2ML may cause headache, constipation, a feeling of warmth or flushing, redness, and irritation at the site of injection. Most of these side effects of PERISET INJECTION 2ML do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ondansetron, Palanosetron, Granisetron, or any other medicines, please tell your doctor. PERISET INJECTION 2ML should be given to children only in doses advised by the doctor based on the child’s body weight or body surface area. If you are pregnant or breastfeeding, you must inform your doctor before receiving PERISET INJECTION 2ML.

Uses of PERISET INJECTION 2ML

Prevention and treatment of nausea and vomiting

Directions for Use

PERISET INJECTION 2ML will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

PERISET INJECTION 2ML contains Ondansetron that blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting caused by chemotherapy in adults and children and also after surgery. Additionally, PERISET INJECTION 2ML can be used to prevent nausea and vomiting caused by radiotherapy for cancer in adults.

How PERISET INJECTION 2ML Works

PERISET INJECTION 2ML contains Ondansetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

Storage

Store in a cool and dry place away from sunlight
Side effects of Periset Injection 2ml
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink plenty of fluids to stay hydrated and replace the lost electrolytes.
  • Eat small, frequent meals of bland foods like crackers, toast, or plain rice.
  • Avoid heavy or fatty foods that can worsen nausea.
  • Use relaxation techniques like deep breathing or meditation to manage stress and anxiety.
  • Minimize exposure to strong smells or odors that can trigger nausea.
  • Ensure good airflow in the room by keeping it well-ventilated and maintaining a comfortable temperature.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

What if I have taken an overdose of PERISET INJECTION 2ML

PERISET INJECTION 2ML is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include sudden loss of vision, severe constipation, feeling light-headed, or fainting. There is no specific antidote for Ondansetron overdose. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

If you are allergic to Ondansetron, Palanosetron, Granisetron, or any other medicines, please tell your doctor. PERISET INJECTION 2ML should be given to children only in doses as advised by the doctor based on the child’s body weight or body surface area. PERISET INJECTION 2ML should be used during pregnancy or breastfeeding after consultation with a doctor. If you have problems with levels of sodium, magnesium, and potassium salts in your blood, inform your doctor before taking PERISET INJECTION 2ML. 

Drug-Drug Interactions

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OndansetronAnagrelide
Severe

Drug-Drug Interactions

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How does the drug interact with Periset Injection 2ml:
Taking Periset Injection 2ml with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Periset Injection 2ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OndansetronAnagrelide
Severe
How does the drug interact with Periset Injection 2ml:
Taking Periset Injection 2ml with anagrelide increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Periset Injection 2ml alongside anagrelide can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Periset Injection 2ml:
When Vilazodone is taken with Periset Injection 2ml, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in body).

How to manage the interaction:
There may be a possibility of interaction between Vilazodone and Periset Injection 2ml, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Periset Injection 2ml:
Using Tapentadol together with Periset Injection 2ml might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although taking Periset Injection 2ml along with tapentadol can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Periset Injection 2ml:
When Periset Injection 2ml, is taken with Vortioxetine it can cause serotonin syndrome (A condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Periset Injection 2ml along with Vortioxetine can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Periset Injection 2ml:
When Periset Injection 2ml, is taken with furazolidone it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Periset Injection 2ml along with furazolidone can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Periset Injection 2ml:
Using Periset Injection 2ml together with Sumatriptan might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Co-administration of Periset Injection 2ml along with sumatriptan can lead to an interaction, it should be taken only if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Periset Injection 2ml:
Taking Periset Injection 2ml with Iloperidone increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Periset Injection 2ml along with Iloperidone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Periset Injection 2ml:
Taking Periset Injection 2ml and Sotalol can increase the risk or severity of irregular heart rhythms which can be severe.

How to manage the interaction:
Although taking Periset Injection 2ml and Sotalol can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Periset Injection 2ml:
When Periset Injection 2ml is taken with paroxetine, can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Periset Injection 2ml along with paroxetine can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.

  • Drink any other liquid at least 30 minutes after eating food. 

  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Habit Forming

No

Therapeutic Class

ANTIEMETICS
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Alcohol

Unsafe

Avoid consuming alcohol while taking PERISET INJECTION 2ML as this medicine can interact with alcohol and may worsen the side effects.

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Pregnancy

Safe if prescribed

If you are pregnant, inform your doctor before taking PERISET INJECTION 2ML. Your doctor will weigh the benefits and risks before prescribing this medicine.

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Breast Feeding

Safe if prescribed

If you are a nursing mother, inform your doctor before taking PERISET INJECTION 2ML. Your doctor will weigh the benefits and risks before prescribing this medicine.

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Driving

Safe

PERISET INJECTION 2ML usually does not affect your driving ability. However, do not drive if you feel any discomfort.

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Liver

Caution

Take PERISET INJECTION 2ML with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Safe if prescribed

PERISET INJECTION 2ML may be safe to use in patients with kidney problems if prescribed by a doctor.

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Children

Caution

PERISET INJECTION 2ML should be used in children only in doses advised by the doctor based on child’s body weight or body surface area.

Have a query?

FAQs

PERISET INJECTION 2ML belongs to a class of drugs called antiemetics used to prevent nausea and vomiting during chemotherapy.

PERISET INJECTION 2ML works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

You are not recommended to take erythromycin with PERISET INJECTION 2ML as it may increase the risk of severe irregular heart rhythm. However, please consult your doctor before taking other medicines with PERISET INJECTION 2ML.

PERISET INJECTION 2ML may cause constipation as a side effect. It is not necessary for everyone taking PERISET INJECTION 2ML to experience this side effect. However, if the condition persists or worsens, please consult a doctor.

PERISET INJECTION 2ML should be used with caution in patients suffering from liver problems. However, inform your doctor if you have any liver problems before taking PERISET INJECTION 2ML so that the dose may be adjusted appropriately.

Yes, PERISET INJECTION 2ML may be used to prevent nausea and vomiting after surgery. PERISET INJECTION 2ML blocks serotonin (a chemical) action which is responsible for causing nausea and vomiting.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
Other Info - PER0084

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