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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
PG Nac-50mg Capsule is used to reduce pain and swelling associated with conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It contains diclofenac and misoprostol which works by inhibiting the release of chemical messengers that cause pain and protecting the stomach lining from acid. In some cases, this medicine may cause side effects such as diarrhoea, stomach/abdominal pain, nausea, heartburn, drowsiness, and dizziness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Theia Health Care Pvt Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

About PG Nac-50mg Capsule

PG Nac-50mg Capsule belongs to a class of non-steroidal anti-inflammatory drugs used to reduce pain and swelling in the joints associated with conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis (pain and stiffness in the backbone). Arthritis is a condition that causes swelling of one or more joints resulting in pain and stiffness of joints that worsen over time. The arthritis symptoms include joint pain, stiffness, redness, tenderness, swelling in and around joints, and reduced movement of joints.

PG Nac-50mg Capsule is a combination drug containing diclofenac and misoprostol. Diclofenac works by blocking the chemical effect of an enzyme called cyclo-oxygenase (COX), which produces prostaglandins (mediators of pain and inflammation) that are responsible for the sense of pain and inflammation (redness and swelling). Misoprostol is a prostaglandin that helps to protect the stomach from diclofenac's irritating effects. It works by protecting the stomach lining by reducing the amount of acid in contact with it.

Take PG Nac-50mg Capsule as prescribed by your doctor. Depending on your medical conditions, you are advised to take PG Nac-50mg Capsule for as long as your doctor has prescribed it for you. You may experience diarrhoea, stomach/abdominal pain, nausea, heartburn, drowsiness, and dizziness. Most of the side effects of PG Nac-50mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before using the PG Nac-50mg Capsule , tell your doctor if you have had a heart attack or stroke, stomach or bowel disorder, liver disease, porphyria ( inherited blood disorder), asthma, high blood pressure, diabetes, and stomach or intestinal bleeding. Do not take PG Nac-50mg Capsule if you are a pregnant or breastfeeding woman. Consumption of alcohol should be avoided during the treatment with PG Nac-50mg Capsule as it may lead to an increased risk of liver damage. PG Nac-50mg Capsule is not recommended for use in children. Limit alcoholic beverages while on this medication.

Uses of PG Nac-50mg Capsule

PG Nac-50mg Capsule is used to treat joint and muscle conditions that cause pain and inflammation. The detailed uses of PG Nac-50mg Capsule are as follows:

  • Rheumatoid arthritis: PG Nac-50mg Capsule is used to reduce joint pain, stiffness, and swelling in autoimmune joint inflammation.
  • Osteoarthritis: PG Nac-50mg Capsule minimizes pain and improves movement in age-related joint degeneration.
  • Ankylosing spondylitis: PG Nac-50mg Capsule helps to reduce spinal inflammation and stiffness.
  • Acute musculoskeletal pain: PG Nac-50mg Capsule is also used to provide temporary relief from muscle strains, sprains, and other soft tissue injuries.

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Directions for Use

  • Take PG Nac-50mg Capsule with food or as advised by your doctor.
  • It is advised to take PG Nac-50mg Capsule 2 to 4 times daily; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

Key Benefits

PG Nac-50mg Capsule is used to treat aches and pains and musculoskeletal and joint pain problems due to arthritis. PG Nac-50mg Capsule contains diclofenac and misoprostol. Diclofenac works by blocking the chemical effect of an enzyme called cyclo-oxygenase (COX), which produces prostaglandins (mediators of pain and inflammation) that are responsible for the sense of pain and inflammation (redness and swelling). Misoprostol is a prostaglandin that helps to protect the stomach from diclofenac's irritating effects. It works by protecting the stomach lining by reducing the amount of acid in contact with it.

How PG Nac-50mg Capsule Works

PG Nac-50mg Capsule is a combination drug containing diclofenac and misoprostol. Diclofenac works by blocking the chemical effect of an enzyme called cyclo-oxygenase (COX), which produces prostaglandins (mediators of pain and inflammation) that are responsible for the sense of pain and inflammation (redness and swelling). Misoprostol is a prostaglandin that helps to protect the stomach from diclofenac's irritating effects. It works by protecting the stomach lining by reducing the amount of acid in contact with it.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of PG Nac-50mg Capsule

Take PG Nac-50mg Capsule only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include stomach pain, nausea, vomiting, diarrhoea, confusion, drowsiness, low muscle tone, uncontrollable shaking of a part of the body, seizures, shortness of breath, fever, and fast, pounding, or slow heartbeat. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Consumption of alcohol should be avoided during the treatment with PG Nac-50mg Capsule . Patients with stomach ulcers, gastric bleeding, heart failure, and high blood pressure should not take PG Nac-50mg Capsule . If pregnant or breastfeeding, do not take PG Nac-50mg Capsule without talking with the doctor. PG Nac-50mg Capsule is not recommended for children below 18 years old. Seek medical help immediately if you have signs of a heart attack or stroke. Stop using PG Nac-50mg Capsule and call your doctor immediately if you notice heart problems, kidney problems, liver problems, or stomach bleeding signs.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with PG Nac-50mg Capsule:
Co-administration of PG Nac-50mg Capsule with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with PG Nac-50mg Capsule is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
How does the drug interact with PG Nac-50mg Capsule:
Coadministration of PG Nac-50mg Capsule and Naproxen can increase the risk or severity of side effects.

How to manage the interaction:
Taking PG Nac-50mg Capsule and Naproxen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with PG Nac-50mg Capsule:
Co-administration of Rivaroxaban together with PG Nac-50mg Capsule may increase the risk of unsual bleeding.

How to manage the interaction:
Co-administration of PG Nac-50mg Capsule and Rivaroxaban can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacPonatinib
Severe
How does the drug interact with PG Nac-50mg Capsule:
Taking PG Nac-50mg Capsule with Ponatinib can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between PG Nac-50mg Capsule and Ponatinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
How does the drug interact with PG Nac-50mg Capsule:
Concomitant use of PG Nac-50mg Capsule with dabigatran may increase the risk of stomach bleeding.

How to manage the interaction:
Taking PG Nac-50mg Capsule with dabigatran together possibly results in an interaction, it can be taken if your doctor has advised it. You should consult a doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, light headedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
DiclofenacOxaprozin
Severe
How does the drug interact with PG Nac-50mg Capsule:
Taking PG Nac-50mg Capsule and oxaprozin can increase the risk of side effects.

How to manage the interaction:
Co-administration of PG Nac-50mg Capsule and oxaprozin can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with PG Nac-50mg Capsule:
Co-administration use of PG Nac-50mg Capsule with Dalteparin may increase the risk of bleeding complications.

How to manage the interaction:
Although taking Dalteparin with PG Nac-50mg Capsule may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
How does the drug interact with PG Nac-50mg Capsule:
Co-administration of PG Nac-50mg Capsule and tenofovir alafenamide may cause kidney problems.

How to manage the interaction:
There may be a possible interaction between PG Nac-50mg Capsule and Tenofovir alafenamide but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
DiclofenacValdecoxib
Severe
How does the drug interact with PG Nac-50mg Capsule:
Taking Valdecoxib with PG Nac-50mg Capsule may increase risk of side effects.

How to manage the interaction:
There may be a possible interaction between PG Nac-50mg Capsule and Valdecoxib but can be taken if prescribed by doctor. However, consult your doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medications without consulting a doctor.
How does the drug interact with PG Nac-50mg Capsule:
Coadministration of PG Nac-50mg Capsule with fondaparinux may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between PG Nac-50mg Capsule and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulfate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.
  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.
  • In chronic arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize the level of cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short time (10-15 min). Use back support like a rolled-up towel to minimise pain at the back of your curve. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Habit Forming

No

Therapeutic Class

[ANALGESICS]

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Alcohol

Safe if prescribed

Do not consume alcohol along with PG Nac-50mg Capsule as it can cause unpleasant side-effects like gastric bleeding.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant; your doctor will prescribe PG Nac-50mg Capsule only if the benefits outweigh the risks. Taking PG Nac-50mg Capsule in the last 20 weeks of pregnancy may cause serious kidney or heart problems in the unborn baby.

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Breast Feeding

Consult your doctor

While PG Nac-50mg Capsule may pass in the lactating mother's breast milk, So, do it is advisable to take it only if prescribed by your doctor.

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Driving

Safe if prescribed

PG Nac-50mg Capsule may cause dizziness and drowsiness. So, if you observe such symptoms, do not drive.

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Liver

Consult your doctor

Limited information was available for the use of PG Nac-50mg Capsule in patients suffering from liver impairment. Please consult your doctor if you have any concerns regarding using PG Nac-50mg Capsule in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Consult your doctor

Limited information was available for the use of PG Nac-50mg Capsule in patients suffering from kidney impairment. Please consult your doctor if you have any concerns regarding using PG Nac-50mg Capsule in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

PG Nac-50mg Capsule not recommended for children under 18 years of age.

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Heart

PG Nac-50mg Capsule is not recommended in cardiac patients due to its adverse effects. However, if prescribed, extreme caution should be exercised.

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Geriatrics

Consult your doctor

PG Nac-50mg Capsule should be used under caution in geriatric patients. Please consult your physician.

FAQs

PG Nac-50mg Capsule is used to reduce pain and swelling associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

PG Nac-50mg Capsule contains diclofenac and misoprostol. Diclofenac works by blocking the action of cyclo-oxygenase (COX) enzyme in the body involved in the production of certain chemical substances such as prostaglandins that cause pain and swelling. Misoprostol is a prostaglandin that helps to protect the stomach from diclofenac's irritating effects. Thereby, PG Nac-50mg Capsule helps in relieving pain and swelling associated with different types of arthritis.

No, PG Nac-50mg Capsule is not a narcotic pain killer. It belongs to the non-steroidal anti-inflammatory drugs (NSAIDs) group of medications.

Yes, PG Nac-50mg Capsule can cause dizziness in some patients. They may experience symptoms such as the feeling of fainting, weakness, or lightheadedness.

PG Nac-50mg Capsule may increase the risk of heart problems such as heart attack, especially when used in high doses or for a prolonged duration, and in patients who are smokers, have high blood pressure, diabetes, or high cholesterol. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking PG Nac-50mg Capsule . However, it is recommended to take PG Nac-50mg Capsule in the dose and for the duration as prescribed by your doctor.

PG Nac-50mg Capsule is not recommended for asthma patients as it may worsen the condition. Therefore, please inform your doctor if you have asthma or a history of asthma due to the use of aspirin or any other non-steroidal drugs.

No, PG Nac-50mg Capsule does not cure arthritis. PG Nac-50mg Capsule is only used to relieve symptoms of arthritis such as joint pain, swelling, and stiffness.

PG Nac-50mg Capsule is used to treat pain associated with arthritis. If you have a toothache, it is recommended that you consult your doctor before using PG Nac-50mg Capsule .

PG Nac-50mg Capsule may cause gastrointestinal problems. Therefore, do not take PG Nac-50mg Capsule if you have acid reflux or abdominal pain without consulting the doctor.

It's generally not recommended to take PG Nac-50mg Capsule with blood pressure medication without consulting your doctor as it may increase blood pressure and reduce the effectiveness of blood pressure medications.

The common side effects of PG Nac-50mg Capsule include diarrhoea, stomach or abdominal pain, nausea, heartburn, drowsiness, and dizziness. Most of the side effects of PG Nac-50mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Country of origin

India

Manufacturer/Marketer address

S-94 Medha Appartment Mayu Vihar Delhi East Delhi Dl 110091 In
Other Info - PGN0001

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