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compositionComposition:PIMOZIDE-2MG
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Prescription Medicine
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Pimoz 2mg Tablet is used to treat schizophrenia and Tourette syndrome. It contains Pimozide which works by inhibiting the receptor (dopamine) in the brain that regulates mood, behaviour and emotions. In some cases, this medicine may cause side effects such as drowsiness, excessive sweating, dizziness, dry mouth, constipation, weight gain, and blurred vision. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PIMOZIDE-2MG

Manufacturer/Marketer :

Mova Pharmaceutical Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Pimoz 2mg Tablet

Pimoz 2mg Tablet is an oral medication prescribed to help control severe motor and vocal tics in people living with Tourette's syndrome. This medicine is typically reserved for individuals whose symptoms have not improved with other standard treatments. It works on the central nervous system to help reduce the frequency and intensity of these involuntary movements and sounds.

To get the best results, you must take this medicine consistently every day, exactly as directed by your healthcare provider. You can take the tablet with or without food, but it is best to choose one method and stick to it at the same time each day. Incorporating stress-reduction techniques and maintaining a regular sleep schedule can also help manage your symptoms, as stress and fatigue are common triggers for tics.

While taking Pimoz 2mg Tablet, you may experience some common side effects such as drowsiness, dry mouth, and constipation. However, you must contact your doctor immediately if you experience serious symptoms, such as a fast or irregular heartbeat, severe muscle stiffness, or uncontrollable movements of your face or tongue. Regular monitoring by your doctor is necessary to ensure the medication is working safely.

Before starting this medication, talk to your doctor if you have a history of heart rhythm problems, seizures, or liver issues. Do not take this if you have congenital long QT syndrome, a history of irregular heartbeats, or low levels of potassium or magnesium in your blood. It is also unsuitable for anyone taking certain medicines that can affect heart rhythm.

Pimoz 2mg Tablet can interact dangerously with other medications, including certain antibiotics, antidepressants, and heart medications, which can raise the risk of serious heart issues. You should avoid alcohol and smoking while taking this medicine, as they can worsen drowsiness and alter how the drug works in your body. If you are pregnant, breastfeeding, or are an older adult, talk to your doctor to discuss whether this medication is safe for you.

Uses of Pimoz 2mg Tablet

Here is the main condition where Pimoz 2mg Tablet is used to help control severe involuntary movements and vocal sounds:

  • Tourette's Syndrome Tics: Pimoz 2mg Tablet is used to reduce the frequency and severity of both motor (physical) and phonic (vocal) tics in patients who have not responded satisfactorily to other standard therapies.

Key Benefits

Pimoz 2mg Tablet provides several important benefits by helping control tics and improving day-to-day functioning:

  • Reduces Motor and Vocal Tics: It helps decrease the frequency and severity of involuntary movements and vocalisations associated with Tourette's syndrome.
  • Relieves Physical Discomfort: By reducing repetitive movements, it helps lessen muscle strain, fatigue, and discomfort caused by frequent tics.
  • Improves Daily Functioning: Better control of tics can make it easier to participate in school, work, and social activities with greater confidence.
  • Supports Emotional Well-Being: Reduced tic severity may help lower the stress, embarrassment, and anxiety often associated with Tourette's syndrome, improving overall quality of life.
Side effects of Pimoz 2mg Tablet
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Quit smoking as smoking impairs erectile function by significantly damaging blood vessels.
  • Maintain a healthy weight as overweight can cause erectile dysfunction.
  • Exercise regularly as physical activity enhances blood flow and overall health, benefiting erectile function.
  • Consume a healthy diet loaded with whole grains, fruits and vegetables.
  • Limit alcohol consumption as excessive alcohol intake can impair erectile function.
  • Manage stress by practicing techniques such as yoga, relaxation exercises or meditation.
  • In case erectile dysfunction is due to psychological factors, consider couple counselling or sex therapy to address relationship and anxiety issues.
  • Openly discuss your concerns with your partner.
  • Eat smaller meals and chew food thoroughly.
  • Try foods with softer textures.
  • If you have difficulty swallowing liquids, use thickener.
  • Learn new swallowing techniques from a speech and language therapist.
  • Avoid alcohol and caffeine as these may dry your throat and mouth making it more difficult to swallow.
  • Consider alternative forms of feeding, such as feeding tubes through nose or a hole into your stomach.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Directions for Use

  • Pimoz 2mg Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow Pimoz 2mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Pimoz 2mg Tablet Works

Pimoz 2mg Tablet contains pimozide, an antipsychotic medicine that helps control the symptoms of Tourette's syndrome. Pimoz 2mg Tablet works by blocking dopamine receptors in the brain. Dopamine is a natural chemical messenger involved in controlling movement, behaviour, and emotions. In people with Tourette's syndrome, excessive dopamine activity is thought to contribute to involuntary movements and vocal sounds. By reducing the effects of dopamine, Pimoz 2mg Tablet helps calm overactive nerve signals and suppress unwanted tics. Together, these actions help reduce the frequency and severity of motor and vocal tics, improving daily functioning and quality of life.
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Alcohol

Unsafe

Avoid consumption of alcohol with Pimoz 2mg Tablet as it may increase the risk of drowsiness and other adverse effects.

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Pregnancy

Unsafe

Pimoz 2mg Tablet is not recommended for use during pregnancy especially in the third trimester as it may cause unwanted side effects to the baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Pimoz 2mg Tablet is usually not recommended for breastfeeding mothers as it may be excreted in human milk in small amounts. Therefore, please consult a doctor if you are breastfeeding.

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Driving

Unsafe

Pimoz 2mg Tablet may cause dizziness, blurred vision or drowsiness. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after taking Pimoz 2mg Tablet.

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Liver

Caution

Take Pimoz 2mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Pimoz 2mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Pimoz 2mg Tablet is not recommended for children below 12 years as the safety and effectiveness were not established.

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Heart

Unsafe

Pimoz 2mg Tablet is not recommended in cardiac patients due to its adverse effects. However, if prescribed extreme caution should be exercised.

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Geriatrics

Caution

Pimoz 2mg Tablet can be given in elderly patients with extreme caution, due to the increased risk of death.

What if I have taken an overdose of Pimoz 2mg Tablet

If you take too much of this medicine, seek emergency medical attention or contact a poison control center immediately. Symptoms of an overdose may include severe muscle stiffness, extreme drowsiness, low blood pressure, or a dangerously irregular heartbeat.

Diet & Lifestyle Advise

  • Avoid grapefruit: Do not eat grapefruit or drink grapefruit juice while taking this medicine. Grapefruit can increase the amount of the drug in your bloodstream, raising the risk of severe side effects.
  • Stay hydrated: Drink plenty of water throughout the day to help manage dry mouth and prevent constipation.
  • Eat a high-fiber diet: Consume fruits, vegetables, and whole grains to help keep your digestion regular, as this medication can cause constipation.
  • Manage stress: Practice relaxation techniques such as mindfulness, deep breathing exercises, or gentle yoga, as stress can increase the frequency of tics.
  • Get regular medical checks: Keep all appointments for blood tests and heart monitoring (ECGs) as recommended by your doctor to ensure the medicine is safe for your heart.
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How Soon It Starts Working

The time required for Pimoz 2mg Tablet to start to work: Pimoz 2mg Tablet shows its action within 3 to 6 hours of administration. The time for which the effects of Pimoz 2mg Tablet last: Pimoz 2mg Tablet effect lasts for 24 hours.

What if you forget to take Pimoz 2mg Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure what to do, talk to your doctor or pharmacist.

Storage

• Store Pimoz 2mg Tablet tablets at room temperature, ideally between 15°C and 30°C (59°F to 86°F). • Keep the medication in its original container, tightly closed, to protect it from moisture and direct light.

Drug Warnings

  • Attend Regular ECG Monitoring: Your doctor will likely perform an electrocardiogram (ECG) before you start taking this medicine and periodically during treatment to monitor your heart's rhythm.
  • Avoid Driving Until You Know Its Effects: Do not drive, operate machinery, or perform dangerous activities until you know how this medication affects you, as it can cause significant drowsiness.
  • Avoid Alcohol: Avoid drinking alcohol, as it can dangerously increase the sedative effects of this medicine.
  • Report Unusual Muscle Movements: Tell your doctor immediately if you notice any unusual, uncontrollable muscle movements, especially in your face, lips, or tongue.
  • Do Not Stop Suddenly: Never stop taking this medicine abruptly, as doing so can cause your tics to worsen suddenly.

Drug-Drug Interactions

verifiedApollotooltip

Here are the medicines that may interact with Pimoz 2mg Tablet and increase the risk of serious side effects or reduce treatment safety:

  • QT-prolonging medicines: Do not take this medication with other drugs that affect heart rhythm, such as certain antibiotics (like erythromycin or clarithromycin), antimalarials, or certain heart medications.
  • Antidepressants: Medicines like sertraline, fluoxetine, or paroxetine can increase the levels of Pimoz 2mg Tablet in your blood, raising the risk of serious heart side effects.
  • Central Nervous System depressants: Taking this medicine with sleeping pills, anxiety medications, muscle relaxants, or strong pain relievers can cause extreme drowsiness and slowed breathing.

PimozideAmisulpride
Critical
PimozideTetrabenazine
Critical

Drug-Drug Interactions

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PimozideAmisulpride
Critical
How does the drug interact with Pimoz 2mg Tablet:
Taking Pimoz 2mg Tablet with Amisulpride can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Pimoz 2mg Tablet with Amisulpride is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
PimozideTetrabenazine
Critical
How does the drug interact with Pimoz 2mg Tablet:
Coadministration of Pimoz 2mg Tablet and Tetrabenazine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Pimoz 2mg Tablet and Tetrabenazine together is not recommended as it can lead to an interaction, but it can be taken if your doctor advises. However, contact your doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhoea, or vomiting. Do not discontinue any medications without consulting your doctor.
PimozideAprepitant
Critical
How does the drug interact with Pimoz 2mg Tablet:
Using Pimoz 2mg Tablet together with aprepitant may significantly increase the blood levels of Pimoz 2mg Tablet. High blood levels of Pimoz 2mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Aprepitant and Pimoz 2mg Tablet together is not recommended; as it can lead to an interaction, you can take them if your doctor advises you to. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, get immediate medical help. Do not discontinue any medications without consulting a doctor.
PimozideParoxetine
Critical
How does the drug interact with Pimoz 2mg Tablet:
Combining Paroxetine with Pimoz 2mg Tablet can effect the rhythm of the heart

How to manage the interaction:
Taking Paroxetine with Pimoz 2mg Tablet is not recommended, but should be taken if advised by a doctor. However, if you experience chest tightness, irregular heartbeat, blurred vision and nausea contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
PimozideClozapine
Critical
How does the drug interact with Pimoz 2mg Tablet:
When Clozapine is taken with Pimoz 2mg Tablet, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Clozapine with Pimoz 2mg Tablet there may be a possibility of interaction, but it can be taken if prescribed by a doctor. Call a doctor immediately if you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
PimozideFosaprepitant
Critical
How does the drug interact with Pimoz 2mg Tablet:
When Pimoz 2mg Tablet is taken with Fosaprepitant, it can increase the Pimoz 2mg Tablet levels in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Fosaprepitant with Pimoz 2mg Tablet is not recommended, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, prolonged diarrhea, or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PimozideMetoclopramide
Critical
How does the drug interact with Pimoz 2mg Tablet:
Coadministration of Metoclopramide with Pimoz 2mg Tablet can increase the risk of negative side effects.

How to manage the interaction:
Taking Pimoz 2mg Tablet with Metoclopramide is not recommended, as it can possibly lead to an interaction, but it can be taken if prescribed by the doctor. However, if you experience muscle pain or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult a doctor. Do not stop using any medications without a doctor’s advice.
PimozideClarithromycin
Critical
How does the drug interact with Pimoz 2mg Tablet:
Combining Clarithromycin with Pimoz 2mg Tablet can increase the risk of heart rhythm problems.

How to manage the interaction:
Co-administration of Clarithromycin and Pimoz 2mg Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like irregular heartbeat, chest tightness, blurred vision or nausea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
PimozideFlecainide
Critical
How does the drug interact with Pimoz 2mg Tablet:
Coadministration of Flecainide with Pimoz 2mg Tablet can increase the risk of developing irregular heart rhythms.

How to manage the interaction:
Taking Flecainide with Pimoz 2mg Tablet is generally avoided, but it can be taken if advised by a doctor. However, if you experience dizziness, shortness of breath, or palpitations, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
PimozideHydroxyzine
Critical
How does the drug interact with Pimoz 2mg Tablet:
Taking Hydroxyzine with Pimoz 2mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Hydroxyzine with Pimoz 2mg Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip

Here are the important food and drink considerations while taking Pimoz 2mg Tablet:

  • Grapefruit and Grapefruit Juice: Avoid these completely, as they slow down the breakdown of this medication in the liver, leading to potentially dangerous levels of the drug in your body.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[NEUROLEPTIC]

FAQs

Pimoz 2mg Tablet is used to treat schizophrenia and tourette' s syndrome.
Pimoz 2mg Tablet contains Pimozide that works by inhibiting the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour and emotions. Thereby, Pimoz 2mg Tablet prevents dopamine overactivity and helps in controlling psychotic illness. Also, Pimoz 2mg Tablet decreases uncontrolled movements or outbursts of sounds or words (tics). Thus, helps in lowering the number of tics in Tourette’s syndrome patients.
You are not recommended to take Pimoz 2mg Tablet with levodopa (antiparkinson drug) as it may decrease the effectiveness of levodopa and increase the risk of adverse effects such as low blood pressure, drowsiness, light-headedness and dizziness. However, please consult your doctor before using Pimoz 2mg Tablet with any other medicines.
Pimoz 2mg Tablet is not recommended for elderly people with dementia (decline in memory, behaviour, thinking and ability to do daily activities) as it may increase the risk of life-threatening adverse effects. Therefore, inform your doctor if you have dementia before taking Pimoz 2mg Tablet.
Pimoz 2mg Tablet may cause dizziness as a temporary adverse effect. However, if the condition persists or worsens, please consult a doctor.
Pimoz 2mg Tablet should be used with caution in patients suffering from fits as it may worsen the condition. Therefore, inform your doctor if you have a history of fits before taking Pimoz 2mg Tablet.
Pimoz 2mg Tablet may cause side effects like drowsiness, excessive sweating, dizziness, urinating at night, dry mouth, constipation, weight gain, blurred vision or impotence (erectile dysfunction) in men. Most of these side effects of Pimoz 2mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
No, you should avoid alcohol. Mixing alcohol with this medication can cause extreme drowsiness, dizziness, and slow your reaction times. Talk to your doctor if you have concerns about avoiding alcohol.
Dry mouth is a common side effect. You can manage this by sipping water frequently, chewing sugarless gum, or sucking on sugar-free hard candies. Talk to your doctor if the dryness becomes severe or persistent.
Some patients may experience weight changes or an increased appetite while taking this medicine. Eating a balanced diet and staying active can help manage this effect. Talk to your doctor for personalized dietary advice.
No, you must not stop taking this medicine suddenly, even if you feel completely better. Stopping abruptly can cause your tics to return or trigger withdrawal symptoms. Talk to your doctor about how to slowly reduce your dose when it is time to stop.
Yes, this medication can alter the electrical activity of your heart, which can lead to serious irregular heartbeats. Your doctor will perform regular ECG tests to monitor your heart safety. Talk to your doctor immediately if you feel dizzy or notice a pounding heartbeat.
This medication should only be used during pregnancy if the potential benefit justifies the risk to the developing baby. If you are pregnant or planning a pregnancy, talk to your doctor to discuss your treatment options.
Your doctor may order regular blood tests to check your electrolyte levels, particularly potassium and magnesium, as low levels can increase the risk of serious heart side effects. Talk to your doctor or pharmacist to learn more about these safety checks.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.6911 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Pimozide Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Pimozide Pimozide. 2011. [Accessed on 22 Mar 2019]Check here
  4. Drugs and Lactation Database (LactMed) [Internet]. 2006. [Accessed on 20 Feb. 2020]Check here
  5. Pimozide Pimozide. 2002. [Accessed on 22 Mar. 2019]Check here
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed on 22 Mar. 2019]Check here
  7. R. M. Finder, R. N. Brogden, Phyllis R. Sawyer, T. M. Speight, Rosalind Spencer, & G. S. Avery. Pimozide: A Review of Its Pharmacological Properties and Therapeutic Uses in Psychiatry. Springer Link. November 2012. [Accessed on 24th August 2024]Check here

Country of origin

India
Other Info - PI74990
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