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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Pioglit MF 15 Tablet

Pioglit MF 15 Tablet is a combination prescription medicine used to control high blood sugar in adults with type 2 diabetes. It is prescribed when a single medication, along with diet and exercise, is not enough to keep blood sugar levels in a healthy range. By helping your body use insulin better, this medicine plays an important role in daily diabetes management.

You should take this medicine consistently every day exactly as prescribed by your doctor. It is usually taken with meals to reduce the chance of experiencing an upset stomach. To get the best results, you must combine this medication with a healthy diet, regular physical activity, and routine blood sugar monitoring as advised by your healthcare team.

While taking Pioglit MF 15 Tablet , some people may experience mild side effects like a temporary upset stomach, cold-like symptoms, or gradual weight gain. However, you must contact your doctor immediately if you notice serious symptoms, such as sudden shortness of breath, severe swelling in your legs, or signs of liver damage like yellowing of your skin or eyes.

Before starting Pioglit MF 15 Tablet , tell your doctor about your complete medical history. Do not take this medicine if you have severe kidney disease, active liver disease, diabetic ketoacidosis, or severe congestive heart failure. Your doctor will evaluate your health to make sure this combination is safe and appropriate for your specific condition.

This medicine can interact with other substances, including alcohol, which significantly increases the risk of a rare but serious condition called lactic acidosis. You should also consult your doctor before using this medicine if you are pregnant, planning to become pregnant, breastfeeding, or if you are an older adult, as special precautions or monitoring may be required.

Uses of Pioglit MF 15 Tablet

Pioglit MF 15 Tablet is used in the treatment of type 2 diabetes. The detailed uses of Pioglit MF 15 Tablet are as follows:

  • Type 2 diabetes mellitus: Pioglit MF 15 Tablet is used to improve blood sugar control in adults whose blood sugar levels are not adequately managed by diet, exercise, or other single diabetes medications alone.

Key Benefits

Pioglit MF 15 Tablet helps improve blood sugar control by maintaining steady daily glucose levels and preventing sharp spikes. It also supports long-term health by reducing the risk of serious diabetes complications and protecting vital organs.

Benefits may include:

  • Helps maintain steady daily blood sugar levels and prevents sharp spikes that cause fatigue or sluggishness.
  • Reduces the long-term risk of serious diabetes complications, including nerve damage, kidney problems, and vision loss.
  • Simplifies your daily treatment routine by combining two different therapeutic actions into a single, easy-to-take tablet.
  • Helps your body use existing insulin more effectively, reducing sugar absorbed from food and produced by the liver.
  • Lowers the risk of sudden, unexpected drops in blood sugar (hypoglycemia).
  • Helps you manage your health with greater confidence and peace of mind.
Side effects of Pioglit MF 15 Tablet
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Directions for Use

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can interfere with how the medicine is released into your body.
  • Take the tablet with meals. This helps lower the risk of experiencing stomach upset, nausea, or diarrhoea.
  • Try to take your dose at the same time every day to establish a consistent routine and keep a steady amount of medicine in your body.
  • Always follow your doctor's exact instructions regarding how often to take your medicine and when to have your regular blood tests.

How Pioglit MF 15 Tablet Works

Pioglit MF 15 Tablet contains Pioglitazone (thiazolidinedione) and Metformin (biguanide). • Metformin works primarily in your liver. It significantly reduces the amount of sugar your liver produces and releases into your blood. It also decreases the amount of sugar your intestines absorb from food. • Pioglitazone works directly in your body's muscle and fat tissues. It acts as an insulin sensitiser, which helps your cells respond much better to your body's own insulin. This allows your muscles to absorb sugar from your blood more effectively and use it for daily energy.
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Alcohol

Unsafe

Not recommended with alcohol as it may result in a harmful decrease or increase in levels of blood sugar depending on how much alcohol a patient has consumed.

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Pregnancy

Caution

Not recommended in pregnancy. Pioglit MF 15 Tablet treatment should be stopped and replaced with any other alternative drug from other blood sugar-lowering agents on the recommendation of a doctor. You must tell your doctor if you are pregnant, think you may be pregnant or are planning to have a baby.

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Breast Feeding

Caution

Not recommended for breastfeeding mothers. Do not use Pioglit MF 15 Tablet if you are breastfeeding or are planning to breastfeed, as a doctor's consultation is required.

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Driving

Safe if prescribed

It is safe to use while driving or operating heavy machinery. This medicine will not affect your ability to drive or use machines, but care should be taken if you experience abnormal vision or anything that affects your ability to drive.

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Liver

Caution

Pioglit MF 15 Tablet should be used with caution in patients with liver disease, as Pioglit MF 15 Tablet has been found to cause harmful interactions in them. A doctor's recommendation is required before taking this drug.

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Kidney

Caution

Pioglit MF 15 Tablet should be taken with caution in patients with kidney disease. In rare cases, serious interactions have been found in kidney patients, called lactic acidosis; thus, a doctor's consultation is required before taking this drug.

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Children

Unsafe

Pioglit MF 15 Tablet is not recommended for use in children and adolescents under 18 years. Talk to your doctor for better alternative blood sugar-lowering agents in diabetic children.

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Heart

Consult your doctor

Pioglit MF 15 Tablet is not contraindicated in heart patients. It is often prescribed to reduce the risk of cardiovascular death and hospitalisation for heart failure in adults with type 2 diabetes and established cardiovascular disease.

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Geriatrics

Consult your doctor

While Pioglit MF 15 Tablet is safe to be taken by older patients, it is critical to exercise caution and monitor for potential adverse effects, such as dehydration, low blood pressure, and urinary tract infections, which are more common in older adults.

What if I have taken an overdose of Pioglit MF 15 Tablet

If you suspect an overdose or if you experience severe symptoms like extreme weakness, hyperventilation, shivering, or confusion, seek immediate emergency medical attention or call your local poison control centre right away.

Diet & Lifestyle Advise

  • Keep carbs consistent: Eat regular, balanced meals with a consistent amount of complex carbohydrates to help prevent sudden rises or drops in your blood sugar levels.
  • Stay active: Engage in regular moderate physical activity, like walking or swimming, which naturally helps your body use insulin more efficiently. Always check with your doctor before starting a new exercise routine.
  • Monitor your weight: Because this medicine can cause your body to hold onto extra fluid, weigh yourself regularly and report any sudden weight gain to your healthcare provider.
  • Limit alcohol: Avoid heavy alcohol consumption, as it significantly increases the risk of low blood sugar and a serious condition called lactic acidosis.

Have a query?

How Soon It Starts Working

  • The time required for Pioglit MF 15 Tablet to start to work: The time required for Pioglit MF 15 Tablet to start to work is 1 to 3 hours after administration.
  • The time for which the effects of Pioglit MF 15 Tablet last: The duration of action for Pioglit MF 15 Tablet is not clinically established.

What if you forget to take Pioglit MF 15 Tablet

If you miss a dose, take it with food as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Watch for swelling: Check your ankles, feet, and legs daily for any unusual swelling, and tell your doctor immediately if you notice fluid retention or rapid weight gain.
  • Keep your medical appointments: Attend all scheduled appointments for blood tests, as your doctor needs to monitor your liver function, kidney function, and long-term blood sugar levels (HbA1c).
  • Know your blood sugar levels: Learn the symptoms of low blood sugar (such as sweating, shaking, and dizziness) and high blood sugar (such as extreme thirst and frequent urination) so you can take appropriate action.
  • Prepare for stressful events: During times of physical stress, such as fever, infection, injury, or surgery, your blood sugar levels may change, and your doctor may need to adjust your treatment plan temporarily.

Drug-Drug Interactions

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Drug-Drug Interaction:

  • Contrast dyes: If you need an X-ray or scan that uses an injected dye, you may need to stop taking Pioglit MF 15 Tablet temporarily to protect your kidneys. Talk to your doctor before any medical imaging procedure.
  • Water pills (diuretics) and steroids: Medicines like furosemide or prednisone can raise your blood sugar levels, which may reduce the effectiveness of Pioglit MF 15 Tablet .
  • Other diabetes medicines: Taking Pioglit MF 15 Tablet alongside insulin or certain other blood-sugar-lowering drugs can increase your risk of low blood sugar (hypoglycemia).

Drug-Food Interaction:

  • Alcohol: Drinking alcohol while taking Pioglit MF 15 Tablet increases the risk of a dangerous buildup of lactic acid in the blood and can cause unpredictable changes in your blood sugar.

Drug-Disease Interaction:

  • Kidney disease: Do not take Pioglit MF 15 Tablet if you have severe kidney impairment, as it can cause the medication to build up to dangerous levels in your body.
  • Heart failure: Pioglit MF 15 Tablet can cause fluid retention, which can worsen active or severe congestive heart failure.
  • Active liver disease: Do not take Pioglit MF 15 Tablet if you have active liver problems, as it requires healthy liver function to be processed safely.
Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Pioglit MF 15 Tablet:
Co-administration of Iopromide with Metformin and Pioglitazone can increase the risk of side effects.

How to manage the interaction:
Taking Iopromide with Metformin and Pioglitazone is not recommended, please consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Pioglit MF 15 Tablet:
Co-administration of Metformin and Pioglitazone with Gatifloxacin can cause both hypoglycaemia (low blood glucose) and, less frequently, hyperglycaemia (high blood glucose).

How to manage the interaction:
There is a possibility of interaction between Metformin and Pioglitazone with Gatifloxacin but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms like tremor, hunger, weakness, sweating. Do not discontinue without consulting a doctor.
Critical
How does the drug interact with Pioglit MF 15 Tablet:
Co-administration of Iopamidol with Pioglitazone and Metformin can increase the risk of side effects.

How to manage the interaction:
Taking Metformin and Pioglitazone with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
Critical
How does the drug interact with Pioglit MF 15 Tablet:
Co-administration of Iomeprol with Pioglitazone and Metformin can increase the risk of side effects.

How to manage the interaction:
Taking Metformin and Pioglitazone with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
Critical
How does the drug interact with Pioglit MF 15 Tablet:
Co-administration of Metformin and Pioglitazone with Metrizamide together can cause the risk of side effects.

How to manage the interaction:
Taking Metformin and Pioglitazone with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Pioglit MF 15 Tablet:
Co-administration of Metformin and Pioglitazone with Iodamide may decrease the kidney function.

How to manage the interaction:
Taking Metformin and Pioglitazone with Iodamide is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
Critical
How does the drug interact with Pioglit MF 15 Tablet:
Co-administration of Metformin and Pioglitazone with Iodixanol may decrease the kidney function.

How to manage the interaction:
Taking Metformin and Pioglitazone with Iodixanol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Pioglit MF 15 Tablet:
Co-administration of Pioglitazone and Metformin with Acetazolamide may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Although there is a possible interaction between Pioglitazone and Metformin and Acetazolamide, you can take these medicines together if prescribed by your doctor. However, if you have symptoms such as difficulty breathing, fatigue, or loss of appetite, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pioglit MF 15 Tablet:
The combined use of Pioglitazone and Metformin with Zonisamide may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Coadministration Pioglitazone and Metformin with Zonisamide can lead to an interaction, it can be taken if prescribed by your doctor. However, if you experience any symptoms such as fatigue, loss of appetite, slow or irregular heartbeat, breathing difficulty, consult a doctor immediately. Do not stop using any medication without a doctor's advice.
How does the drug interact with Pioglit MF 15 Tablet:
Co-administration of Teriflunomide with Metformin and Pioglitazone may increase the risk of liver damage.

How to manage the interaction:
Although taking Metformin and Pioglitazone with Teriflunomide together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as itching, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIDIABETICS AND ANTIHYPERGLYCEMICS]

FAQs

Pioglit MF 15 Tablet is used to treat Type II diabetes (non-insulin-dependent diabetes). It lowers blood sugar by activating cell switches (PPAR) to take up free glucose from the blood and use it for energy production. It also decreases the production of glucose in the liver.

Pioglit MF 15 Tablet can cause fluid retention, which can cause heart failure. The doctor usually recommends starting from a lower dose and increasing the dose slowly while treating patients who are at risk of heart failure. Heart failure is reported mainly in patients taking insulin Pioglit MF 15 Tablet simultaneously.

There have been rare cases of liver damage in patients taking Pioglit MF 15 Tablet . The doctor usually screens the patient continuously during the course of treatment with Pioglit MF 15 Tablet . A patient is advised to visit a doctor strictly as per the doctor's advice.

Pioglit MF 15 Tablet is contradictory when used in patients with high blood pressure. A doctor's consultation is required before taking this drug in a patient with high blood pressure.

Pioglit MF 15 Tablet is safe to take before driving a vehicle or operating machinery, provided blood sugar levels are stable. However, a patient is advised to take proper precautions and make sure that Pioglit MF 15 Tablet is not taken with another blood sugar-lowering agent.

Not recommended to be taken with contraceptives. Pioglit MF 15 Tablet decreases the activity of oral contraceptives like Ethinyl estradiol by almost 30% and leads to failure of contraception.

Type 2 diabetes is a condition where the body is unable to produce sufficient insulin, or the insulin it produces doesn't work correctly or is not utilised by the body. This can cause high blood sugar levels (hyperglycemia). Symptoms of type 2 diabetes include increased thirst, frequent urination, slow, increased hunger, fatigue, and blurred vision.

Pioglit MF 15 Tablet should be swallowed as a whole with a glass of water. Avoid crushing, chewing, or breaking it.

Don't stop taking Pioglit MF 15 Tablet without consulting your doctor, even if your blood sugar levels return to normal. Stopping the medication suddenly can cause your blood sugar levels to fluctuate, leading to potential complications. Your doctor prescribed Pioglit MF 15 Tablet to help manage your type 2 diabetes, and they need to assess your condition before making any changes to your treatment plan. Consult your doctor before stopping or adjusting your medication, as they will provide personalised guidance to ensure your blood sugar levels remain stable and under control.

Avoid or limit alcohol consumption while taking Pioglit MF 15 Tablet , as it can interact with the medication and increase the risk of low or high blood sugar levels, as well as a rare but serious condition called lactic acidosis. Additionally, alcohol can worsen certain health conditions, such as nerve damage or liver disease. If you do choose to drink alcohol, do so in moderation and closely monitor your blood sugar levels.

Common side effects of Pioglit MF 15 Tablet may include stomach aches, feeling sick (nausea), vomiting, diarrhoea, loss of appetite, localised swelling (oedema), weight gain, headache, respiratory infection, numbness, taste disturbance, etc. Most of these side effects of Pioglit MF 15 Tablet do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

To make an informed decision, consult your healthcare professional, who can assess your individual situation and provide personalised guidance on using Pioglit MF 15 Tablet while breastfeeding.

Pioglit MF 15 Tablet should be taken with caution in patients with kidney disease. In rare cases, serious interactions have been found in kidney patients, called lactic acidosis; thus, a doctor's consultation is required before taking Pioglit MF 15 Tablet .

Pioglit MF 15 Tablet is recommended not to be used in children. Pioglit MF 15 Tablet is a medication typically prescribed for adults over 18 years with type 2 diabetes.

Pioglit MF 15 Tablet is not recommended during pregnancy as there is not much information about its safety during pregnancy. If you are pregnant or thinking of getting pregnant, talk to your doctor, as they will need to review your treatment. They can suggest a different medicine that is safer for you to take during pregnancy.

Store in a cool and dry place away from sunlight. Keep Pioglit MF 15 Tablet out of reach and out of sight to children.

No, Pioglit MF 15 Tablet is not indicated for treating type 1 diabetes. Pioglit MF 15 Tablet is a medication specifically designed to treat type 2 diabetes, and it's not suitable for managing type 1 diabetes.

Pioglit MF 15 Tablet can interact with various other drugs, including those used to manage diabetes, blood pressure, heart conditions, and thyroid disorders, as well as steroids and blood thinners. Always let your healthcare professional know about all the medications you are currently taking to reduce risks. They will help you navigate potential interactions and ensure safe treatment. Consulting your healthcare professional before combining Pioglit MF 15 Tablet with any other medications is key.

Pioglit MF 15 Tablet contains Pioglitazone (thiazolidinedione) & Metformin (biguanide).

Yes, some people experience gradual weight gain while taking this medicine. This can be due to your body using sugar more efficiently or because of fluid retention. If you notice rapid, sudden weight gain, especially with swelling in your legs or feet, contact your doctor immediately, as this can be a sign of a more serious condition.

You should contact your healthcare provider right away if you notice new or worsening swelling in your ankles, feet, or legs. Fluid retention can sometimes be a sign of heart strain, and your doctor will need to evaluate your heart health to decide if you should continue taking this medicine.

It is highly recommended to avoid or severely limit alcohol while taking this medicine. Alcohol increases the risk of a rare but life-threatening condition called lactic acidosis, and it can also make your blood sugar levels drop dangerously low. Talk to your doctor about what is safe for you.

You may begin to see an improvement in your daily blood sugar readings within a couple of weeks, but it can take several weeks to a few months to see the full therapeutic effect on your HbA1c levels. Keep taking the medication consistently as prescribed, and talk to your doctor if you have concerns about your progress.

Yes, you should always take this medicine with a meal. Taking it with food helps minimize common digestive side effects, such as nausea, stomach upset, and diarrhoea, which are common when starting this medication.

When taken on its own, this medicine is less likely to cause low blood sugar than some other diabetes medications. However, the risk of low blood sugar increases if you skip meals, drink alcohol, exercise intensely, or take it with other diabetes medicines like insulin. Talk to your doctor about how to recognize and treat low blood sugar.

Lactic acidosis is a rare but extremely serious medical emergency where lactic acid builds up in the blood. It is a recognized risk associated with Metformin, particularly in patients with kidney problems. If you experience unusual muscle pain, trouble breathing, deep tiredness, or cold limbs, seek immediate emergency care.

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Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - PIO0031
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