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Pivikto 200 mg/50 mg Tablet is used to treat advanced or metastatic breast cancer. It contains Alpelisib. In breast cancers with a PIK3CA gene mutation, a protein called PI3K is involved in helping the cancer cells multiply and grow. By blocking the action of PI3K, Alpelisib helps stop the growth and spread of the cancer. Common side effects of this medication are rash, decreased appetite, weight loss, nausea, mouth sores, hair loss, tiredness and weakness, vomiting, allergic reactions, skin reactions, high blood sugar levels, lung problems, and diarrhoea.
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About Pivikto 200 mg/50 mg Tablet
Pivikto 200 mg/50 mg Tablet belongs to a class of kinase inhibitors. It is used in conjunction with fulvestrant to treat postmenopausal women and men with hormone receptor (HR)-positive, HER2-negative, PIK3CA-mutated, advanced, or metastatic breast cancer.
Pivikto 200 mg/50 mg Tablet contains Alpelisib. In breast cancers with a PIK3CA gene mutation, a protein called PI3K is involved in helping the cancer cells multiply and grow. By blocking the action of PI3K, Alpelisib helps stop the growth and spread of the cancer.
To treat your condition effectually, continue using Pivikto 200 mg/50 mg Tablet for as long as your doctor has prescribed it. The most common side effects include rash, decreased appetite, weight loss, nausea, mouth sores, hair loss, tiredness and weakness, vomiting, changes in certain blood tests, allergic reactions, skin reactions, high blood sugar levels, lung problems, and diarrhea. You should talk to your doctor if you persistently experience these side effects.
Avoid taking Pivikto 200 mg/50 mg Tablet if you are allergic to it. It is not recommended for use in pregnancy. Lactating women do not breastfeed during treatment with Pivikto 200 mg/50 mg Tablet and for one week after the last dose. Alcohol should be avoided during treatment with this medicine. Safety and effectiveness in children have not been established.
Uses of Pivikto 200 mg/50 mg Tablet
Pivikto 200 mg/50 mg Tablet is used in the treatment of Advanced or metastatic breast cancer. The detailed uses of Pivikto 200 mg/50 mg Tablet are as follows:
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Directions for Use
Medicinal Benefits
Pivikto 200 mg/50 mg Tablet contains Alpelisib, which belongs to a class of kinase inhibitors. It is used in conjunction with fulvestrant to treat postmenopausal women and men with hormone receptor (HR)-positive, HER2-negative, PIK3CA-mutated, advanced, or metastatic breast cancer. In breast cancers with a PIK3CA gene mutation, a protein called PI3K is involved in helping the cancer cells multiply and grow. By blocking the action of PI3K, Alpelisib helps stop the growth and spread of the cancer.
How Pivikto 200 mg/50 mg Tablet Works
Storage
What if I have taken an overdose of Pivikto 200 mg/50 mg Tablet
Drug Warnings
It is not advised during pregnancy, nursing, or for children or young adults under 18. Before taking the Pivikto 200 mg/50 mg Tablet , inform your doctor about all your medical conditions (especially lung infections, diarrhoea, diabetics, kidney or liver impairment), sensitivities or allergic conditions, and all medications you use. Consult your doctor right away if you become pregnant while taking Pivikto 200 mg/50 mg Tablet . Exposure of an unborn child to this medication could cause congenital disabilities, so you should not become pregnant or father a child while on this medication. Effective birth control is required throughout treatment and at least one week after treatment. You should not breastfeed while taking this medication for two weeks after your last dose.
Diet & Lifestyle Advise
Habit Forming
Therapeutic Class
Alcohol
Caution
Avoid alcohol consumption while on treatment with Pivikto 200 mg/50 mg Tablet .
Pregnancy
Unsafe
Pivikto 200 mg/50 mg Tablet should not be used during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.
Breast Feeding
Caution
Lactating women should not breastfeed throughout Pivikto 200 mg/50 mg Tablet treatment and for one week following the final dosage.
Driving
Caution
Pivikto 200 mg/50 mg Tablet does not influence the ability to drive or use machines. However, go only if you are alert, as the Pivikto 200 mg/50 mg Tablet may cause weakness or tiredness in some people.
Liver
Caution
Limited information is available. Inform your doctor before taking the Pivikto 200 mg/50 mg Tablet if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
Caution
No dose adjustment is recommended for patients with mild to moderate renal impairment (CLcr 30 to < 90 mL/min). The effect of severe renal impairment (CLcr < 30 mL/min) on alpelisib is unknown. So, inform your doctor before taking the Pivikto 200 mg/50 mg Tablet if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Children
Unsafe
Safety and effectiveness in patients below the age of 18 years have not been established. Hence, use is not recommended.
Heart
Take Pivikto 200 mg/50 mg Tablet with caution, especially if you have a history of heart diseases/conditions. The dose may be adjusted by your doctor as required.
Geriatrics
Caution
Pivikto 200 mg/50 mg Tablet should be used with caution in elderly patients. Please consult your doctor before use.
Pivikto 200 mg/50 mg Tablet is used to treat Advanced or metastatic breast cancer.
Pivikto 200 mg/50 mg Tablet contains Alpelisib. In breast cancers with a PIK3CA gene mutation, a protein called PI3K is involved in helping the cancer cells multiply and grow. By blocking the action of PI3K, Alpelisib helps stop the growth and spread of the cancer.
Hyperglycemia is common with Pivikto 200 mg/50 mg Tablet and can be severe. Your healthcare provider will monitor your blood sugar levels before you start and during treatment with Pivikto 200 mg/50 mg Tablet . Your healthcare provider may monitor your blood sugar levels more often if you have a history of Type 2 diabetes. Tell your healthcare provider right away if you develop symptoms of hyperglycemia, including excessive thirst, dry mouth, more frequent urination than usual or a higher amount of urine than normal and increased appetite with weight loss.
It is critical to understand that Alpelisib is not a traditional chemotherapy drug and functions in a different manner. It works by specifically targeting cancer cells and preventing their growth and spread.
While taking Pivikto 200 mg/50 mg Tablet , make sure you visit your doctor at all the appointments to ensure that treatment works. Regular monitoring of blood and lipid tests and weight checks are required. An effective way of contraception should be used by both men and women while taking the Pivikto 200 mg/50 mg Tablet .
Based on findings from animal studies, Pivikto 200 mg/50 mg Tablet may impair fertility in males and females of reproductive potential. Discuss the risks of taking this medication with your doctor.
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