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  3. Plackcef 200mg/500mg Tablet XL

Plackcef 200mg/500mg Tablet XL, Pack of 1 Tablet
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Plackcef 200mg/500mg Tablet XL is used to treat bacterial infections. It contains Cefixime and Dicloxacillin which work by killing infection-causing bacteria. In some cases, this medicine may cause side effects such as vomiting, nausea, diarrhoea, stomach pain, and indigestion. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

CEFIXIME-200MG + DICLOXACILLIN-500MG

Manufacturer/Marketer :

Placker Life Sciences

Consume Type :

ORAL

Return Policy :

Not Returnable

About Plackcef 200mg/500mg Tablet XL

Plackcef 200mg/500mg Tablet XL belongs to a class of drugs called antibiotics used to treat several bacterial infections of the urinary tract, ears, nose, throat, chest, and lungs. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. Plackcef 200mg/500mg Tablet XL does not work against infections caused by the virus.

Plackcef 200mg/500mg Tablet XL is a combination of two antibiotics, namely: Cefixime and Dicloxacillin.  Plackcef 200mg/500mg Tablet XL works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damages the bacterial cell wall and kills bacteria.

Take Plackcef 200mg/500mg Tablet XL as prescribed by your doctor. You are advised to take Plackcef 200mg/500mg Tablet XL for as long as your doctor has prescribed it for you based on your medical condition. You may experience vomiting, nausea, diarrhea, stomach pain, indigestion, or vaginal itching in some cases. Most of these side effects of Plackcef 200mg/500mg Tablet XL do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Plackcef 200mg/500mg Tablet XL, penicillins, or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Plackcef 200mg/500mg Tablet XL. Dicloxacillin may reduce the effectiveness of birth control pills. Therefore, discuss with your doctor about other contraceptive methods such as using non-hormonal birth control measures such as condoms, spermicide, or diaphragm to avoid pregnancy while taking Plackcef 200mg/500mg Tablet XL. Drive only if you are alert as Plackcef 200mg/500mg Tablet XL may reduce alertness or cause confusion. You are recommended to complete the full course of Plackcef 200mg/500mg Tablet XL as prescribed by your doctor for effective results.

Uses of Plackcef 200mg/500mg Tablet XL

Treatment of Bacterial infections

Directions for Use

• Plackcef 200mg/500mg Tablet XL is best taken before meals to improve absorption and reduce the chance of stomach discomfort.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Plackcef 200mg/500mg Tablet XL as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Plackcef 200mg/500mg Tablet XL is a combination of two broad-spectrum antibiotics: Cefixime and Dicloxacillin that act against both aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) gram-negative and gram-positive bacteria. Plackcef 200mg/500mg Tablet XL is used in the treatment of several bacterial infections. Plackcef 200mg/500mg Tablet XL interferes with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damages the bacterial cell wall and kills bacteria.

How Plackcef 200mg/500mg Tablet XL Works

Plackcef 200mg/500mg Tablet XL is a combination of two antibiotics, namely: Cefixime and Dicloxacillin.  Plackcef 200mg/500mg Tablet XL works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damages the bacterial cell wall and kills bacteria.

Storage

Keep Plackcef 200mg/500mg Tablet XL out of reach and sight of children.

What if I have taken an overdose of Plackcef 200mg/500mg Tablet XL

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

If you are allergic to Plackcef 200mg/500mg Tablet XL, penicillins, or any other medicines, please tell your doctor. If you have kidney or liver problems, asthma, bleeding or blood clotting disorder, or stomach or intestinal disorder such as inflammation of the large intestine, inform your doctor before taking Plackcef 200mg/500mg Tablet XL. If you are pregnant or breastfeeding, please inform your doctor before taking Plackcef 200mg/500mg Tablet XL. Dicloxacillin may reduce the effectiveness of birth control pills. Therefore, discuss with your doctor about other contraceptive methods such as using non-hormonal birth control measures such as condoms, spermicide, or diaphragm to avoid pregnancy while taking Plackcef 200mg/500mg Tablet XL. Drive only if you are alert as Plackcef 200mg/500mg Tablet XL may reduce alertness or cause confusion. You are recommended to complete the full course of Plackcef 200mg/500mg Tablet XL as prescribed by your doctor for effective results. Plackcef 200mg/500mg Tablet XL may interact with certain tests such as glucose (sugar) in urine and give unusual results. Therefore, inform the doctor that you are using Plackcef 200mg/500mg Tablet XL before undergoing any tests.

Drug-Drug Interactions

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CefiximeCholera, live attenuated
Severe
DicloxacillinMethotrexate
Severe

Drug-Drug Interactions

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CefiximeCholera, live attenuated
Severe
How does the drug interact with Plackcef 200mg/500mg Tablet XL:
Co-administration of Plackcef 200mg/500mg Tablet XL with Cholera vaccine may reduce the effectiveness of the vaccine.

How to manage the interaction:
Talk to your doctor before receiving the cholera vaccine if you are currently being treated with Plackcef 200mg/500mg Tablet XL or have been treated within the last 14 days. To ensure adequate vaccine response, you should not receive cholera vaccine until at least 14 days after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
DicloxacillinMethotrexate
Severe
How does the drug interact with Plackcef 200mg/500mg Tablet XL:
Co-administration of methotrexate with Plackcef 200mg/500mg Tablet XL can increase the levels and effects of methotrexate. This can increase the risk or severity of serious infections.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Plackcef 200mg/500mg Tablet XL, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, mouth ulcers, paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches. Consult a doctor immediately. Do not stop using medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Plackcef 200mg/500mg Tablet XL to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like cheese, yogurt, kombucha, sauerkraut, and kimchi can help to restore the good bacteria of the intestine.
  • Include fiber-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread and brown rice should be included in your diet.
  • Make sure you drink plenty of water or other fluids every day while you are taking Plackcef 200mg/500mg Tablet XL.
  • Avoid alcohol consumption as it may increase adverse effects.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Plackcef 200mg/500mg Tablet XL Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Interaction of Plackcef 200mg/500mg Tablet XL with alcohol is unknown. Please consult a doctor before consuming alcohol while using Plackcef 200mg/500mg Tablet XL.

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Pregnancy

Caution

Please consult a doctor if you are pregnant or planning for pregnancy. Plackcef 200mg/500mg Tablet XL is given to pregnant women only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Caution

It is unknown whether Plackcef 200mg/500mg Tablet XL is excreted in human milk. Plackcef 200mg/500mg Tablet XL is given to breastfeeding mothers if the doctor thinks benefits are more significant than risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Plackcef 200mg/500mg Tablet XL may decrease alertness or confuse. Therefore, drive only if you are alert after taking Plackcef 200mg/500mg Tablet XL.

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Liver

Caution

Take Plackcef 200mg/500mg Tablet XL with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Plackcef 200mg/500mg Tablet XL with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Plackcef 200mg/500mg Tablet XL is given to children only if prescribed by a doctor.

Have a query?

FAQs

Plackcef 200mg/500mg Tablet XL is used to treat bacterial infections of the urinary tract, ears, nose, throat, chest, and lungs.

Plackcef 200mg/500mg Tablet XL contains Cefixime and Dicloxacillin which work by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damages the bacterial cell wall and kills bacteria.

Plackcef 200mg/500mg Tablet XL may be used to treat lung infection caused by bacteria. Plackcef 200mg/500mg Tablet XL is an antibiotic that kills bacteria and prevents the spread of infection. But should be used only when prescribed by a doctor.

Plackcef 200mg/500mg Tablet XL may cause diarrhoea as a common side effect. However, if the condition persists, worsens, or notices blood or mucus in stools, avoid taking Plackcef 200mg/500mg Tablet XL and consult a doctor immediately.

You are not recommended to take Plackcef 200mg/500mg Tablet XL with warfarin as co-administration of these two medicines may increase bleeding risk. However, please consult your doctor before taking Plackcef 200mg/500mg Tablet XL with other medicines.

Plackcef 200mg/500mg Tablet XL is not used to treat viral infections. Plackcef 200mg/500mg Tablet XL is an antibiotic which is used to treat only bacterial infections.

You are not recommended to stop taking Plackcef 200mg/500mg Tablet XL without consulting your doctor as it may worsen the infection or cause recurring symptoms. Therefore, take Plackcef 200mg/500mg Tablet XL for as long as your doctor has prescribed it, and if you experience any difficulty while taking Plackcef 200mg/500mg Tablet XL, please consult your doctor.

Dicloxacillin may reduce the effectiveness of birth control pills. Therefore, discuss with your doctor about other contraceptive methods such as using non-hormonal birth control measures such as condom, spermicide or diaphragm to avoid pregnancy while taking Plackcef 200mg/500mg Tablet XL.

Plackcef 200mg/500mg Tablet XL usually starts working within a few hours, but noticeable symptom improvement may take up to a few days which varies from person to person based on health condition. Always follow the doctor's advice to have optimal results.

If your symptoms persist or fail to improve, consult your doctor. Please note that it may take some time to fully heal your condition, as the treatment process can be gradual. However, if you don't see improvement, your doctor may need to reassess your condition, adjust the dosage, or consider alternative treatments.

Don't stop taking your medication just because you're feeling better! Stopping without completing your prescribed course can lead to incomplete recovery and the return of symptoms. Instead, report your progress to your doctor and follow their advice. They will guide you on how to safely stop the medication.

The common side effects of Plackcef 200mg/500mg Tablet XL, which may occur in some individuals are vomiting, nausea, diarrhoea, stomach pain, indigestion, or vaginal itching. Most of these side effects of Plackcef 200mg/500mg Tablet XL do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India
Other Info - PL87294

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:48 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.5534.pdf
  2. https://www.drugs.com/mtm/cefixime.html
  3. https://www.drugs.com/mtm/dicloxacillin.html
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