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compositionComposition:CEFIXIME-200MG+DICLOXACILLIN-500MG
prescription
Prescription Medicine
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Afixim-DL 200mg/500mg Tablet is used to treat bacterial infections. It contains Cefixime and Dicloxacillin which work by killing infection-causing bacteria. In some cases, this medicine may cause side effects such as vomiting, nausea, diarrhoea, stomach pain, and indigestion. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

CEFIXIME-200MG+DICLOXACILLIN-500MG

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Afixim-DL 200mg/500mg Tablet

Afixim-DL 200mg/500mg Tablet is a prescription oral antibiotic used to treat certain bacterial infections affecting the lungs, throat, skin, urinary tract, and other parts of the body when your doctor considers this combination appropriate. It contains two antibiotics that work together to kill susceptible bacteria. We understand that recovering from a bacterial infection can be uncomfortable and worrying, but taking your medicine correctly gives you the best chance of a full recovery.

For the best results, take Afixim-DL 200mg/500mg Tablet exactly as prescribed and complete the full course, even if you start feeling better after a few days. Most treatment courses last 5 to 10 days, although the exact duration depends on the type and severity of your infection. It is generally recommended to take Afixim-DL 200mg/500mg Tablet on an empty stomach, about 1 hour before or 2 hours after meals, because food may reduce the absorption of dicloxacillin. Drinking plenty of fluids, getting enough rest, and eating a balanced diet can also support your recovery.

Most people tolerate Afixim-DL 200mg/500mg Tablet well. Mild nausea, stomach upset, loose stools, or diarrhea may occur and usually improve as your body adjusts. However, if you develop severe or persistent watery or bloody diarrhea, yellowing of the skin or eyes, difficulty breathing, swelling of the face or throat, or a widespread skin rash, please contact your doctor as soon as possible for urgent medical advice. If you develop signs of a severe allergic reaction such as trouble breathing or swelling of the face, lips, tongue, or throat, seek emergency medical care immediately.

Do not take Afixim-DL 200mg/500mg Tablet if you are allergic to cefixime, dicloxacillin, penicillin antibiotics, cephalosporin antibiotics, or any of the ingredients in Afixim-DL 200mg/500mg Tablet. Tell your doctor before starting treatment if you have weak or damaged kidneys, liver disease, asthma, or a history of severe bowel inflammation (colitis). Afixim-DL 200mg/500mg Tablet does not treat viral infections such as the common cold or flu, or fungal infections, and should only be used for confirmed or suspected bacterial infections.

Afixim-DL 200mg/500mg Tablet may interact with certain medicines, including blood thinners, methotrexate, gout medicines such as probenecid, and some vaccines. Current evidence suggests that most antibiotics, including this combination, are not proven to reduce the effectiveness of birth control pills, unlike rifampicin. However, if you experience severe vomiting or diarrhea while taking Afixim-DL 200mg/500mg Tablet, your contraceptive pill may not be absorbed properly. Speak with your doctor if you have concerns. If you are pregnant, breastfeeding, giving Afixim-DL 200mg/500mg Tablet to a child, or are an older adult, consult your doctor before use. Children require doses based on their age and body weight, while older adults with kidney problems may need closer monitoring.

Uses of Afixim-DL 200mg/500mg Tablet

Afixim-DL 200mg/500mg Tablet is used in the treatment of various bacterial infections. The detailed uses of Afixim-DL 200mg/500mg Tablet are as follows:

  • Severe bacterial respiratory infections: Afixim-DL 200mg/500mg Tablet helps by stopping the growth of bacteria in the lungs and airways, clearing up conditions like severe bronchitis or pneumonia.
  • Skin and soft tissue infections: Afixim-DL 200mg/500mg Tablet targets bacteria that infect deep skin layers, helping to reduce swelling, redness, and pain in wounds, abscesses, or cellulitis.
  • Urinary tract infections (UTIs): Afixim-DL 200mg/500mg Tablet eliminates stubborn bacteria in the urinary tract, relieving painful urination and frequent urges.
  • Bone and joint infections: Afixim-DL 200mg/500mg Tablet penetrates deep into bone tissues to kill bacteria, preventing long-term damage and promoting joint recovery.

Key Benefits

Afixim-DL 200mg/500mg Tablet helps treat susceptible bacterial infections by combining two antibiotics that work against different types of bacteria. By controlling the infection effectively, it supports faster recovery and overall well-being.
Benefits may include:

  • Helps treat susceptible bacterial infections.
  • Combines two antibiotics to provide broad antibacterial coverage against different bacteria.
  • Helps relieve symptoms such as fever, pain, swelling, and discomfort as the infection improves.
  • Supports faster recovery by eliminating infection-causing bacteria.
  • Helps prevent the infection from spreading or returning when the full course is completed.
  • Supports responsible antibiotic use by helping reduce the development of antibiotic resistance when taken as prescribed.
Side effects of Afixim-DL 200mg/500mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Directions for Use

  • Afixim-DL 200mg/500mg Tablet is best taken before meals to improve absorption and reduce the chance of stomach discomfort.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Afixim-DL 200mg/500mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Afixim-DL 200mg/500mg Tablet Works

Afixim-DL 200mg/500mg Tablet contains Cefixime and Dicloxacillin. Cefixime: It is an antibiotic that helps treat bacterial infections by stopping the growth of bacteria and destroying them, helping the body clear the infection. Dicloxacillin: It is an antibiotic that helps treat bacterial infections, including those caused by certain bacteria that can resist some other penicillin antibiotics. It helps stop the growth of bacteria and supports faster recovery from infection.
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Alcohol

Caution

Interaction of Afixim-DL 200mg/500mg Tablet with alcohol is unknown. Please consult a doctor before consuming alcohol while using Afixim-DL 200mg/500mg Tablet.

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Pregnancy

Caution

Please consult a doctor if you are pregnant or planning for pregnancy. Afixim-DL 200mg/500mg Tablet is given to pregnant women only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Caution

It is unknown whether Afixim-DL 200mg/500mg Tablet is excreted in human milk. Afixim-DL 200mg/500mg Tablet is given to breastfeeding mothers if the doctor thinks benefits are more significant than risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Afixim-DL 200mg/500mg Tablet may decrease alertness or confuse. Therefore, drive only if you are alert after taking Afixim-DL 200mg/500mg Tablet.

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Liver

Caution

Take Afixim-DL 200mg/500mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Afixim-DL 200mg/500mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Afixim-DL 200mg/500mg Tablet is given to children only if prescribed by a doctor.

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Heart

Safe if prescribed

Afixim-DL 200mg/500mg Tablet is generally safe for heart patients if prescribed, but should be used under medical supervision.

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Geriatrics

Caution

Afixim-DL 200mg/500mg Tablet can be given in elderly patients with extreme caution, due to the cause of adverse effects like liver/kidney problems,or gastrointestinal problems.

What if I have taken an overdose of Afixim-DL 200mg/500mg Tablet

If you accidentally take too much of Afixim-DL 200mg/500mg Tablet, seek immediate medical attention or call an emergency poison control center. Symptoms of an overdose may include severe stomach pain, vomiting, or seizures.

Diet & Lifestyle Advise

  • Probiotics: Consider taking a probiotic supplement or eating yogurt with active cultures a few hours after your antibiotic dose to help maintain a healthy balance of gut bacteria.
  • Stay Hydrated: Drink plenty of water throughout the day to help your kidneys flush out the medication and keep your body hydrated during recovery.
  • Complete the Course: Always finish the entire prescribed course of Afixim-DL 200mg/500mg Tablet to prevent the bacteria from returning and becoming resistant to antibiotics.
  • Avoid Alcohol: Refrain from drinking alcohol while on this medication, as it can worsen stomach irritation and increase the risk of dizziness or dehydration.
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How Soon It Starts Working

The time required for Afixim-DL 200mg/500mg Tablet to start to work: Afixim-DL 200mg/500mg Tablet ideally shows its action within 1 to 2 hours after administration. The time for which the effects of Afixim-DL 200mg/500mg Tablet last: The duration of action for Afixim-DL 200mg/500mg Tablet is clinically unknown.

What if you forget to take Afixim-DL 200mg/500mg Tablet

If you miss a dose of Afixim-DL 200mg/500mg Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Afixim-DL 200mg/500mg Tablet at room temperature, ideally below 30°C (86°F), in a cool, dry place away from direct sunlight and moisture •Keep the medication securely out of the reach of children and pets

Drug Warnings

  • Complete the full course of treatment: Take Afixim-DL 200mg/500mg Tablet for the entire prescribed duration, even if your symptoms improve before Afixim-DL 200mg/500mg Tablet is finished, to help prevent the infection from returning and reduce antibiotic resistance.
  • Take Afixim-DL 200mg/500mg Tablet as directed: Take Afixim-DL 200mg/500mg Tablet 1 hour before or 2 hours after meals, unless your doctor advises otherwise.
  • Use only for bacterial infections: Afixim-DL 200mg/500mg Tablet treats bacterial infections only and will not work against viral illnesses such as the common cold or flu.
  • Inform your doctor about antibiotic allergies: Tell your healthcare provider before starting treatment if you have ever had an allergic reaction to penicillin, cephalosporins, or any other antibiotics.
  • Inspect Afixim-DL 200mg/500mg Tablet before use: Do not take Afixim-DL 200mg/500mg Tablet if the blister strip is damaged or if the tablets or capsules appear discolored or altered.
  • Discuss contraception if needed: Most antibiotics, including Afixim-DL 200mg/500mg Tablet, are not known to reduce the effectiveness of birth control pills. However, if you experience severe vomiting or diarrhea, oral contraceptives may be less effective. Ask your doctor whether you need additional contraception during this time.
  • Monitor your response to treatment: Contact your doctor if your symptoms do not improve within 48 to 72 hours or if they worsen despite treatment.

Drug-Drug Interactions

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  • Blood thinners (e.g., warfarin): Taking these medicines alongside Afixim-DL 200mg/500mg Tablet may increase the risk of bleeding. Your doctor may monitor your blood clotting more closely.
  • Gout medicines (e.g., probenecid): These medicines may increase the amount of the antibiotic component in the body, raising the risk of side effects.
  • Anti-cancer (e.g., Methotrexate): Taking methotrexate with Afixim-DL 200mg/500mg Tablet may slow its removal from the body and increase the risk of methotrexate-related side effects.
  • Live bacterial vaccines (e.g., oral typhoid vaccine): Antibiotics may reduce the effectiveness of certain live bacterial vaccines. Tell your doctor if you are scheduled to receive a vaccine.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Food: Take Afixim-DL 200mg/500mg Tablet on an empty stomach, as food, especially heavy meals, may reduce the absorption of the dicloxacillin component and make it less effective.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Afixim-DL 200mg/500mg Tablet is used to treat bacterial infections of the urinary tract, ears, nose, throat, chest, and lungs.
Afixim-DL 200mg/500mg Tablet contains Cefixime and Dicloxacillin which work by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damages the bacterial cell wall and kills bacteria.
Afixim-DL 200mg/500mg Tablet may be used to treat lung infection caused by bacteria. Afixim-DL 200mg/500mg Tablet is an antibiotic that kills bacteria and prevents the spread of infection. But should be used only when prescribed by a doctor.
You are not recommended to take Afixim-DL 200mg/500mg Tablet with warfarin as co-administration of these two medicines may increase bleeding risk. However, please consult your doctor before taking Afixim-DL 200mg/500mg Tablet with other medicines.
Afixim-DL 200mg/500mg Tablet is not used to treat viral infections. Afixim-DL 200mg/500mg Tablet is an antibiotic which is used to treat only bacterial infections.
You are not recommended to stop taking Afixim-DL 200mg/500mg Tablet without consulting your doctor as it may worsen the infection or cause recurring symptoms. Therefore, take Afixim-DL 200mg/500mg Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Afixim-DL 200mg/500mg Tablet, please consult your doctor.
If your symptoms persist or fail to improve, consult your doctor. Please note that it may take some time to fully heal your condition, as the treatment process can be gradual. However, if you don't see improvement, your doctor may need to reassess your condition, adjust the dosage, or consider alternative treatments.
The common side effects of Afixim-DL 200mg/500mg Tablet, which may occur in some individuals are vomiting, nausea, diarrhoea, stomach pain, indigestion, or vaginal itching. Most of these side effects of Afixim-DL 200mg/500mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
It is generally recommended to take Afixim-DL 200mg/500mg Tablet 1 hour before or 2 hours after meals, because food can reduce the absorption of dicloxacillin. If taking it on an empty stomach causes significant stomach upset, speak with your doctor before changing how you take Afixim-DL 200mg/500mg Tablet.
Mild diarrhea is a common side effect of antibiotics and often settles on its own. However, if you develop severe, persistent, watery, or bloody diarrhea, especially with stomach cramps or fever, contact your doctor immediately. Do not stop taking Afixim-DL 200mg/500mg Tablet without medical advice unless you develop a life-threatening allergic reaction.
Afixim-DL 200mg/500mg Tablet should only be used during pregnancy if your doctor decides the expected benefits outweigh the potential risks. Always tell your doctor if you are pregnant, planning to become pregnant, or think you may be pregnant before starting treatment.
Although alcohol does not have a major direct interaction with Afixim-DL 200mg/500mg Tablet, it may worsen stomach irritation, dizziness, or dehydration while you are recovering from an infection. Limiting or avoiding alcohol during treatment is recommended.
Current evidence shows that most antibiotics, including Afixim-DL 200mg/500mg Tablet, are not proven to reduce the effectiveness of birth control pills. However, if you develop severe vomiting or diarrhea, your contraceptive pill may not be absorbed properly. In this situation, ask your doctor or pharmacist whether you should use an additional physical method of contraception, such as condoms, until you recover.
No. Dicloxacillin belongs to the penicillin group of antibiotics, and people with a penicillin allergy may develop a serious allergic reaction. Tell your doctor about any previous allergic reactions to penicillin or cephalosporin antibiotics before starting Afixim-DL 200mg/500mg Tablet.
Yes, Afixim-DL 200mg/500mg Tablet may be prescribed for children when your doctor considers it appropriate. The dose is carefully calculated according to the child's age, body weight, the type of infection, and kidney function. Do not give Afixim-DL 200mg/500mg Tablet to a child without medical advice.
No. Afixim-DL 200mg/500mg Tablet works only against bacterial infections. It will not treat viral illnesses such as the common cold, influenza (flu), or most sore throats caused by viruses. Taking antibiotics when they are not needed can contribute to antibiotic resistance and make future bacterial infections harder to treat.

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Country of origin

India

Manufacturer/Marketer address

11-12-23 Road No 1, Income Tax Colony, Sri Rama Krishna Puram, Saroornagar, Hyderabad 500035.
Other Info - AF45435
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