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  3. Plaqstat ASP 20 mg/75 mg Capsule 10's

Plaqstat ASP 20 mg/75 mg Capsule 10's, Pack of 10 CAPSULES
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Plaqstat ASP 20 mg/75 mg Capsule is used to prevent myocardial infarction (heart attack), stroke or peripheral vascular disease. It is also used to lower abnormally elevated cholesterol or fat levels (hyperlipidaemia or dyslipidaemia) in the body. It contains Rosuvastatin and Aspirin, which lowers the bad cholesterol (low-density lipoprotein or LDL) levels and increases good cholesterol levels (high-density lipoprotein or HDL) in the blood. Also, it decreases the formation of blood clots by preventing the platelets from clubbing together. It may cause common side effects such as increased bleeding tendency, nausea, abdominal pain, headache, constipation, muscle pain, weakness, dizziness and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

ASPIRIN-75MG + ROSUVASTATIN-20MG

Manufacturer/Marketer :

Metabolica Lifecare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Plaqstat ASP 20 mg/75 mg Capsule

Plaqstat ASP 20 mg/75 mg Capsule is used for the prevention of heart attack and stroke. A heart attack generally refers to a blocked flow of blood to the heart due to the blockage of the arteries. The blockage is most often a buildup of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries).

Plaqstat ASP 20 mg/75 mg Capsule is composed of rosuvastatin and aspirin. This medicine reduces the bad cholesterol (also known as low-density lipoproteins or LDL), and triglycerides (TG). It also collectively prevents the formation of clots in the blood vessels. Together, Plaqstat ASP 20 mg/75 mg Capsule helps to reduce the risk of heart attack, stroke, and heart-related chest pain (angina).

In some cases, you may experience headache, ankle swelling (oedema), dark urine, muscle weakness, slow heart rate, dizziness, and nausea. Most of these side effects of Plaqstat ASP 20 mg/75 mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Take Plaqstat ASP 20 mg/75 mg Capsule with or without food. Your doctor will advise you on how often you take your medicine based on your medical condition. Try not to stop taking this medicine on your own. Do not chew, break, or crush the medicine.

Avoid taking Plaqstat ASP 20 mg/75 mg Capsule if you are allergic to it. Stopping Plaqstat ASP 20 mg/75 mg Capsule abruptly may worsen your condition and increase your risk of future heart attack. Let your doctor know if you have any active liver disease, bleeding issues, muscle problems, are pregnant or planning to become pregnant or are breastfeeding. Patients should inform the doctor that they are taking Plaqstat ASP 20 mg/75 mg Capsule before any surgery is scheduled or any new medicine is taken.

Uses of Plaqstat ASP 20 mg/75 mg Capsule

Plaqstat ASP 20 mg/75 mg Capsule is used in the prevention of heart attack and stroke. The detailed uses of Plaqstat ASP 20 mg/75 mg Capsule are as follows:

  • Cardiovascular Protection: Plaqstat ASP 20 mg/75 mg Capsule is frequently prescribed to prevent blood clots in individuals at high risk of heart attacks or strokes.
  • Anti-inflammatory Effects: Plaqstat ASP 20 mg/75 mg Capsule is known for its ability to reduce inflammation associated with various medical conditions.
  • Management of Angina: Plaqstat ASP 20 mg/75 mg Capsule supports the management of angina symptoms by enhancing blood flow and reducing the heart's workload.
  • Post-surgical Care: Plaqstat ASP 20 mg/75 mg Capsule is administered after certain surgeries to lower the risk of thromboembolic events, promoting smoother recovery.

Directions for Use

  • Plaqstat ASP 20 mg/75 mg Capsule can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Plaqstat ASP 20 mg/75 mg Capsule as a whole with a glass of water.
  • Do not chew, crush or break it.

Medicinal Benefits

  • Plaqstat ASP 20 mg/75 mg Capsule is composed of Rosuvastatin and Aspirin.
  • Rosuvastatin is an antilipemic agent (cholesterol-lowering) which works by blocking liver enzymes, causing the liver to make less cholesterol.
  • It also lowers the bad cholesterol (low-density lipoprotein or LDL) levels and increases good cholesterol levels (high-density lipoprotein or HDL) in the blood.
  • Aspirin is an anti-platelet drug that decreases blood clot's formation by preventing the platelets from clubbing together.
  • Plaqstat ASP 20 mg/75 mg Capsule helps in the free flow of blood, thereby preventing a heart attack, stroke and other peripheral vascular diseases.
  • Plaqstat ASP 20 mg/75 mg Capsule reduces the risk of coronary events, such as heart attack, stroke and angina (chest pain). 

How Plaqstat ASP 20 mg/75 mg Capsule Works

Plaqstat ASP 20 mg/75 mg Capsule is composed of two medicines, namely: Rosuvastatin and Aspirin. Rosuvastatin belongs to the class of antilipemic (cholesterol-lowering) agents. It works by blocking liver enzymes, causing the liver to make less cholesterol. Rosuvastatin lowers the bad cholesterol (low-density lipoprotein or LDL) levels and increases good cholesterol levels (high-density lipoprotein or HDL) in the blood. Aspirin is a non-steroidal anti-inflammatory drug (NSAID) with anti-platelet action. It decreases the formation of blood clots by preventing the platelets from clubbing together. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose (about 75 mg) to prevent heart attack and stroke. Plaqstat ASP 20 mg/75 mg Capsule helps in the free flow of blood, thereby preventing a heart attack, stroke and other peripheral vascular diseases.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Plaqstat ASP 20 mg/75 mg Capsule

Do not take more than the prescribed dose of Plaqstat ASP 20 mg/75 mg Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Avoid taking Plaqstat ASP 20 mg/75 mg Capsule if you are allergic to Plaqstat ASP 20 mg/75 mg Capsule or any other components present in it.
  • Before taking Plaqstat ASP 20 mg/75 mg Capsule , let your doctor know if you have a history of liver and kidney diseases or allergic reactions to aspirin and rosuvastatin.
  • If you are at risk of internal bleeding (bleeding inside any tissues, organs or joints of your body), a recent injury/surgery or a planned surgery (including dental) in the next few days, coagulation disorders, and active bleeding issues (peptic ulcer, brain haemorrhage), please inform your doctor before starting the medicine. 
  • The doctor might ask you to stop taking Plaqstat ASP 20 mg/75 mg Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery.
  • If you are pregnant, planning to conceive or breastfeeding, it is essential to seek medical advice before starting Plaqstat ASP 20 mg/75 mg Capsule . 
  • Do not drive or operate machinery if you experience dizziness or drowsiness while using Plaqstat ASP 20 mg/75 mg Capsule . 
  • Please do not consume alcohol since it may worsen the side effects like dizziness and increased blood pressure. 
  • Plaqstat ASP 20 mg/75 mg Capsule is not recommended for use in children under 16 years. 

Drug-Drug Interactions

verifiedApollotooltip
AspirinKetorolac tromethamine
Critical
AspirinKetorolac
Critical

Drug-Drug Interactions

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AspirinKetorolac tromethamine
Critical
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule:
Combining Ketorolac tromethamine with Plaqstat ASP 20 mg/75 mg Capsule can increase the risk of adverse effects.

How to manage the interaction:
Taking Plaqstat ASP 20 mg/75 mg Capsule with Ketorolac tromethamine is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice.
AspirinKetorolac
Critical
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule:
Co-administration of Ketorolac and Plaqstat ASP 20 mg/75 mg Capsule may increase the risk of side effects.

How to manage the interaction:
Taking Ketorolac with Plaqstat ASP 20 mg/75 mg Capsule is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual bleeding or bruising, dizziness, tarry stools, coughing up or vomiting fresh or dried blood, severe headache and weakness. Do not stop using any medications without talking to a doctor.
AspirinOmacetaxine mepesuccinate
Severe
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule:
Using omacetaxine together with Plaqstat ASP 20 mg/75 mg Capsule may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Plaqstat ASP 20 mg/75 mg Capsule and Omacetaxine mepesuccinate, you can take these medicines together if prescribed by a doctor. It is important to closely monitor for any signs of bleeding during the treatment and contact a doctor right away if you experience symptoms like bruising, dizziness, or severe headache. Other symptoms to watch out for include red or black stools, weakness, and vomiting. Do not stop using any medications without talking to a doctor.
AspirinIbuprofen
Severe
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule:
Taking Plaqstat ASP 20 mg/75 mg Capsule with ibuprofen may impair the efficacy of Plaqstat ASP 20 mg/75 mg Capsule and increase the risk of developing stomach ulcers and bleeding.

How to manage the interaction:
Although there is a possible interaction between Plaqstat ASP 20 mg/75 mg Capsule and ibuprofen, you can take these medicines together if prescribed by a doctor. However, if you experience severe stomach discomfort, bloating, sudden dizziness or lightheadedness, nausea, vomiting (particularly with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
AspirinDanaparoid
Severe
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule:
Coadministration of Plaqstat ASP 20 mg/75 mg Capsule with danaparoid can increase risk of the bleeding.

How to manage the interaction:
Although there is an interaction between Plaqstat ASP 20 mg/75 mg Capsule and Danaparoid, but it can be taken if prescribed by a doctor. However, If you experience unusual bleeding, unexplained bruises, swelling, headache, feeling lightheaded, blood in your urine or stools, or feeling weak, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
AspirinAcetazolamide
Severe
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule:
Coadministration of Plaqstat ASP 20 mg/75 mg Capsule with Acetazolamide may cause side effects.

How to manage the interaction:
Although there is a possible interaction between Plaqstat ASP 20 mg/75 mg Capsule and acetazolamide, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as ringing in your ears, headache, nausea, vomiting, dizziness, confusion, hallucinations, or rapid breathing, fever, and seizure, please contact a doctor. Do not stop using any medications without talking to a doctor.
AspirinDicoumarol
Severe
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule:
Using warfarin together with Dicoumarol may cause you to bleed more easily.

How to manage the interaction:
Taking Plaqstat ASP 20 mg/75 mg Capsule with Dicoumarol together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any bleeding, it's important to contact a doctor right away. They will be able to help you and provide the necessary care. Do not discontinue any medications without consulting a doctor.
AspirinEdoxaban
Severe
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule:
When edoxaban is used with Plaqstat ASP 20 mg/75 mg Capsule, the risk of bleeding may increase.

How to manage the interaction:
Although there is a possible interaction between Plaqstat ASP 20 mg/75 mg Capsule and edoxaban, you can take these medicines together if prescribed by a doctor. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without consulting a doctor.
AspirinMethazolamide
Severe
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule:
Taking Plaqstat ASP 20 mg/75 mg Capsule with methazolamide may cause side effects.

How to manage the interaction:
Although there is a possible interaction between Plaqstat ASP 20 mg/75 mg Capsule and methazolamide, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as ringing in your ears, headache, nausea, vomiting, dizziness, confusion, hallucinations, or rapid breathing, fever, seizure (convulsions), please contact a doctor. Do not stop using any medications without consulting a doctor.
AspirinDalteparin
Severe
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule:
Using dalteparin with Plaqstat ASP 20 mg/75 mg Capsule, may enhance the risk of bleeding problems.

How to manage the interaction:
Although there is a possible interaction between Plaqstat ASP 20 mg/75 mg Capsule and dalteparin, you can take these medicines together if prescribed by a doctor. However, if you notice unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness while taking these drugs, inform a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Plaqstat ASP 20 mg/75 mg Capsule .
  • A low-cholesterol diet and regular exercise regimen are found to complement treatment with Plaqstat ASP 20 mg/75 mg Capsule effectively.
  • Keep your cholesterol and triglyceride levels under control.
  • Eat at regular intervals and maintain a healthy diet that includes fresh fruits, vegetables.
  • The high-fat meal should be avoided, as it may further increase the risk of a heart attack instead of eating heart-healthy foods.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart disease.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on noticing and managing the early symptoms of heart disease. 

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS

Plaqstat ASP 20 mg/75 mg Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

It is unsafe to consume alcohol since it may worsen the side effects like dizziness and increase blood pressure.

bannner image

Pregnancy

Unsafe

Plaqstat ASP 20 mg/75 mg Capsule is unsafe to use during pregnancy since it has harmful effects on the foetus. If the patient becomes pregnant while using Plaqstat ASP 20 mg/75 mg Capsule , please discontinue immediately. Please consult your doctor if you are planning to conceive or are already pregnant before starting Plaqstat ASP 20 mg/75 mg Capsule .

bannner image

Breast Feeding

Unsafe

Plaqstat ASP 20 mg/75 mg Capsule is not recommended for use if you are a lactating mother since it may affect the breastfed infant. Please consult your doctor before starting Plaqstat ASP 20 mg/75 mg Capsule .

bannner image

Driving

Unsafe

Do not drive or operate machinery if you experience dizziness or drowsiness while using Plaqstat ASP 20 mg/75 mg Capsule . Plaqstat ASP 20 mg/75 mg Capsule can also sometimes cause blurry vision, hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

bannner image

Liver

Caution

Let your doctor know if you have any history of liver disease. Your doctor will weigh the benefits and potential risks before prescribing Plaqstat ASP 20 mg/75 mg Capsule .

bannner image

Kidney

Caution

Let your doctor know if you have any history of kidney disease. Your doctor will weigh the benefits and potential risks before prescribing Plaqstat ASP 20 mg/75 mg Capsule .

bannner image

Children

Unsafe

Plaqstat ASP 20 mg/75 mg Capsule is not recommended for children below the age of 16 years. The safety and efficacy of Plaqstat ASP 20 mg/75 mg Capsule have not been established in children.

Have a query?

FAQs

Plaqstat ASP 20 mg/75 mg Capsule is primarily used to prevent myocardial infarction (heart attack), stroke or peripheral vascular disease. It is also used to lower abnormally elevated cholesterol or fat levels (hyperlipidaemia or dyslipidaemia) in the body.

Plaqstat ASP 20 mg/75 mg Capsule consists of Rosuvastatin and Aspirin. Rosuvastatin works by blocking liver enzymes, causing the liver to make less cholesterol. It lowers the bad cholesterol levels and increases good cholesterol levels in the blood, thus preventing heart attack and stroke. Aspirin is a non-steroidal anti-inflammatory (NSAID) and anti-platelet drug that decreases blood clots formation by preventing the platelets from clubbing together, which is the primary cause for heart attack and stroke.

Plaqstat ASP 20 mg/75 mg Capsule consists of Aspirin. It is a blood-thinning agent and can increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails or using sharp objects. Also, please consult your doctor beforehand if you undergo any surgery.

Please consult your doctor if Plaqstat ASP 20 mg/75 mg Capsule needs to be discontinued before undergoing a dental procedure or any surgery. The doctor might ask you to stop taking Plaqstat ASP 20 mg/75 mg Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery.

Brief your medical history to your doctor if you have any kidney/liver diseases, asthma, active bleeding issues (like peptic ulcer, brain haemorrhage), gastrointestinal disorders, diabetes, musculoskeletal disorder and mental illness before taking Plaqstat ASP 20 mg/75 mg Capsule .

Plaqstat ASP 20 mg/75 mg Capsule can cause dizziness as one of its side effects. Please consult your doctor if you feel dizzy for a longer time. Avoid driving or operating machinery during episodes of dizziness.

Plaqstat ASP 20 mg/75 mg Capsule is generally safe to take for a long time. It works best if you take it for many months or even years. If you're at risk of getting stomach pain, heartburn or constipation, your doctor may prescribe a medicine to treat such side effects, while you're taking Plaqstat ASP 20 mg/75 mg Capsule .

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

Swallow the medicine as a whole with water; do not crush, break or chew it. Your doctor will advise you how often you take your tablets based on your medical condition.

Before taking the Plaqstat ASP 20 mg/75 mg Capsule , let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Low cholesterol diet and regular exercise regime are found to complement treatment with Plaqstat ASP 20 mg/75 mg Capsule effectively.

Yes, in cases, using Plaqstat ASP 20 mg/75 mg Capsule may lead to unexplained muscle pain, tenderness, weakness or cramps. his can happen a few weeks or months after you first start taking this medicine. Contact your doctor if your symptoms continue for more than a few days or get worse.

Adopt a heart-healthy diet, exercise regularly, and avoid smoking and excessive alcohol use to improve drug efficacy and lower cardiovascular risk.

Avoid the use of other painkillers while taking Plaqstat ASP 20 mg/75 mg Capsule . If required, your doctor may suggest paracetamol for relieving pain.

It could be beneficial to take your Plaqstat ASP 20 mg/75 mg Capsule after a meal or snack Keep your meals simple and avoid rich or spicy foods. If your symptoms persist or worsen, see your doctor. Make sure you get enough of rest and drinks.

Plaqstat ASP 20 mg/75 mg Capsule may interact with various medications. Tell your doctor about the medicines you need to take. Your doctor will check the interactions and guide you on how to take them.

Store in a cool and dry place away from sunlight. Keep Plaqstat ASP 20 mg/75 mg Capsule out of sight and reach of children. A medicine take-back program is the best approach to properly dispose of your medicines. To learn about community, take-back initiatives, speak with your pharmacist or contact your local garbage/recycling department.

Plaqstat ASP 20 mg/75 mg Capsule is composed of two medicines, namely: Rosuvastatin (cholesterol-lowering agents) and Aspirin (a non-steroidal anti-inflammatory drug (NSAID) with anti-platelet action).

Country of origin

India

Manufacturer/Marketer address

Plot No-22, Pratham Society, Near Telephone Exchange Wakad Chinchwad Pune Pune Mh 411057 In
Other Info - PLA0464

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 8, 2025 | 2:05 PM IST

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Reference

  1. https://www.centaurpharma.com/downloads/R5A%20and%20R10A.pdf
  2. https://www.ciplamed.com/content/rosulip-asp-capsules
  3. https://www.drugs.com/aspirin.html
  4. https://www.drugs.com/mtm/rosuvastatin.html

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