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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Pleopill AC-20 mg Capsule is used for the prevention of heart attack and stroke. It also lowers the raised level of cholesterol in our body. It blocks the enzyme required to make cholesterol in the body. It reduces the bad cholesterol (also known as low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (also known as high-density lipoproteins or HDL). Also, it prevents the formation of a clot in the blood vessels. Thus, it help to reduce the risk of heart attack, stroke and heart-related chest pain (angina). In some cases, you may experience side effects such as headaches, dizziness, ankle swelling (oedema), slow heart rate, diarrhoea, and nausea.

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Manufacturer/Marketer :

Zinnia Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pleopill AC-20 mg Capsule

Pleopill AC-20 mg Capsule is used for the prevention of heart attack and stroke. It also lowers the raised level of cholesterol in our body. A heart attack generally refers to a blocked flow of blood to the heart due to the blockage of arteries. The blockage is most often a buildup of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries).

Pleopill AC-20 mg Capsule is composed of three medicines namely: Atorvastatin, Clopidogrel and Aspirin. Atorvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body. It reduces the bad cholesterol (also known as low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (also known as high-density lipoproteins or HDL). Clopidogrel and Aspirin are blood thinners (anticoagulants) that collectively prevent the formation of a clot in the blood vessels. It also helps to reduce the increased levels of bad cholesterol (low-density lipoprotein and triglycerides). Together Pleopill AC-20 mg Capsule help to reduce the risk of heart attack, stroke and heart-related chest pain (angina).

You can take Pleopill AC-20 mg Capsule with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you how often you take Pleopill AC-20 mg Capsule based on your medical condition. In some cases, you may experience headaches, dizziness, ankle swelling (oedema), slow heart rate, diarrhoea, and nausea. Most of these side effects of Pleopill AC-20 mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Stopping Pleopill AC-20 mg Capsule abruptly may worsen your condition and increase your risk of a future heart attack. Let your doctor know if you are sensitive to atorvastatin, clopidogrel or aspirin, have any active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), muscle problem (myopathy, rhabdomyolysis), are pregnant or planning to become pregnant or breastfeeding. The patient should inform the doctor that they are taking Pleopill AC-20 mg Capsule before any surgery is scheduled or any new medicine is taken. Atorvastatin present in Pleopill AC-20 mg Capsule is a pregnancy category X drug so it is contraindicated in pregnant women. As it may cause harm to the fetus if administered to a pregnant woman. Pleopill AC-20 mg Capsule is known to cause dizziness, so driving should be avoided.

Uses of Pleopill AC-20 mg Capsule

Pleopill AC-20 mg Capsule is used to prevent heart attacks. The detailed uses of Pleopill AC-20 mg Capsule are as follows:<br/>• Cardiovascular Protection: Pleopill AC-20 mg Capsule is used to prevent heart attacks, strokes, and other cardiovascular events.<br/>• Blood Clot Prevention: Pleopill AC-20 mg Capsule helps to prevent blood clots in people with a history of heart conditions.<br/>• Cholesterol Management: Pleopill AC-20 mg Capsule helps to lower cholesterol levels, reducing the risk of cardiovascular diseases.<br/>

Directions for Use

• Pleopill AC-20 mg Capsule should be taken with food.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Pleopill AC-20 mg Capsule as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Pleopill AC-20 mg Capsule is composed of three medicines namely: Atorvastatin (lipid or cholesterol-lowering medicine), Aspirin (analgesic and anticoagulant) and Clopidogrel (anticoagulant). Together they help in lowering increased bad cholesterol (low-density lipoprotein - LDL) and raise good cholesterol (high-density lipoprotein - HDL). This, in turn, prevents the formation of blood clots and plaque (cholesterol) deposited in the walls of heart arteries thereby minimizing the risk of cardiovascular heart diseases like heart attack and stroke.

How Pleopill AC-20 mg Capsule Works

Pleopill AC-20 mg Capsule is composed of three medicines namely: Atorvastatin, Clopidogrel and Aspirin. Atorvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body. It reduces the bad cholesterol (also known as low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (also known as high-density lipoproteins or HDL). Clopidogrel and Aspirin are blood thinners (anticoagulants) that collectively prevent the formation of a clot in the blood vessels. It also helps to reduce the increased levels of bad cholesterol (low-density lipoprotein and triglycerides). Together Pleopill AC-20 mg Capsule help to reduce the risk of heart attack, stroke and heart-related chest pain (angina).

Storage

Keep out of the sight and reach of children.

What if I have taken an overdose of Pleopill AC-20 mg Capsule

Do not take more than the prescribed dose of Pleopill AC-20 mg Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Let your doctor know if are sensitive to atorvastatin, clopidogrel or aspirin, have any active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), pregnant or planning to become pregnant or breastfeeding. The patient should inform the doctor that they are taking Pleopill AC-20 mg Capsule before any surgery is scheduled or any new medicine is taken. Atorvastatin present in Pleopill AC-20 mg Capsule is a pregnancy category X drug so it is contraindicated in pregnant women. Pleopill AC-20 mg Capsule contains Atorvastatin which can cause muscle problems like myopathy and rhabdomyolysis. The safety and effectiveness of Pleopill AC-20 mg Capsule have not been established, so its use should be avoided in pediatric patients or children less than 12 years of age. Abrupt discontinuation of Pleopill AC-20 mg Capsule may lead to the occurrence of cardiovascular events like heart attack, stroke and angina (heart-related chest pain). Hence, you should consult a doctor before stopping the dose of Pleopill AC-20 mg Capsule .

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Pleopill AC-20 mg Capsule:
Combining Ketorolac tromethamine with Pleopill AC-20 mg Capsule can increase the risk of adverse effects.

How to manage the interaction:
Taking Pleopill AC-20 mg Capsule with Ketorolac tromethamine is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Pleopill AC-20 mg Capsule:
Co-administration of Ketorolac and Pleopill AC-20 mg Capsule may increase the risk of side effects.

How to manage the interaction:
Taking Ketorolac with Pleopill AC-20 mg Capsule is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual bleeding or bruising, dizziness, tarry stools, coughing up or vomiting fresh or dried blood, severe headache and weakness. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pleopill AC-20 mg Capsule:
Taking Pleopill AC-20 mg Capsule together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Pleopill AC-20 mg Capsule with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Pleopill AC-20 mg Capsule:
When Selexipag and Pleopill AC-20 mg Capsule are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Pleopill AC-20 mg Capsule with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
How does the drug interact with Pleopill AC-20 mg Capsule:
Taking Pleopill AC-20 mg Capsule with Posaconazole can increase the blood levels of Pleopill AC-20 mg Capsule. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Pleopill AC-20 mg Capsule, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pleopill AC-20 mg Capsule:
Taking Pleopill AC-20 mg Capsule with dorzolamide may increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Pleopill AC-20 mg Capsule and dorzolamide, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as ringing in your ears, headache, nausea, vomiting, dizziness, confusion, or fever, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Pleopill AC-20 mg Capsule:
Coadministration of Dasatinib with Pleopill AC-20 mg Capsule may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Pleopill AC-20 mg Capsule and Dasatinib, you can take these medicines together if prescribed by a doctor. However, if you notice bruising, swelling, vomiting, headache, dizziness, or weakness inform a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Pleopill AC-20 mg Capsule:
Coadministration of Pleopill AC-20 mg Capsule and Teriflunomide can enhance the risk of liver problems.

How to manage the interaction:
Although co-administration of Pleopill AC-20 mg Capsule with teriflunomide can lead to an interaction, it can be taken if recommended by a doctor. If you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
AspirinDrotrecogin alfa (activated)
Severe
How does the drug interact with Pleopill AC-20 mg Capsule:
Coadministration of Pleopill AC-20 mg Capsule and Drotrecogin alfa may increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Drotrecogin alfa (activated) and Pleopill AC-20 mg Capsule, but it can be taken if prescribed by a doctor. It's important to keep a close eye on any signs of bleeding and let a doctor know right away if you experience any of these symptoms - close monitoring or bleeding. Do not stop using any medications without a doctor's advice.
How does the drug interact with Pleopill AC-20 mg Capsule:
When Ibrutinib is used with Pleopill AC-20 mg Capsule, the risk of bleeding may increase.

How to manage the interaction:
Although there is a possible interaction between Pleopill AC-20 mg Capsule and Ibrutinib, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A low cholesterol diet along with a regular exercise regime is recommended. 
  • As a precautionary measure, you are recommended not to consume alcohol, junk food items from outside, stick to a freshly prepared home-cooked meal and take proper rest, for a speedy recovery.
  • And also try to replace most of your saturated fats with unsaturated fats can reduce total cholesterol and bad cholesterol (LDL cholesterol) in a short span of time.
  • Foods like avocados, olive oil, fatty fish and nuts contain lots of heart-healthy unsaturated fats, so it’s beneficial to eat them regularly.

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS
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Alcohol

Unsafe

Pleopill AC-20 mg Capsule should not be taken until prescribed if you are taking alcohol. Keep your doctor informed if you drink alcohol.

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Pregnancy

Unsafe

Pleopill AC-20 mg Capsule contains Atorvastatin which is a pregnancy category X medicine. It may cause harm to both the pregnant mother and the fetus. Hence, it is not recommended for pregnant women and those who are planning for a pregnancy. Your doctor might prescribe you only in an extreme case.

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Breast Feeding

Caution

Take Pleopill AC-20 mg Capsule only when prescribed, it is known to pass on in a limited quantity via breast milk to the child.

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Driving

Caution

Drive with caution, Pleopill AC-20 mg Capsule usually causes blurry vision and may affect driving ability.

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Liver

Caution

Pleopill AC-20 mg Capsule to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Pleopill AC-20 mg Capsule to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Pleopill AC-20 mg Capsule is not recommended for children below the age of 16 years. The safety and effectiveness of Pleopill AC-20 mg Capsule have not been established in children due to limited testing of this drug on children by competent authorities across the world.

Have a query?

FAQs

Pleopill AC-20 mg Capsule is used for the prevention of heart attack and stroke. It also lowers the raised level of cholesterol in our body.

The use of Pleopill AC-20 mg Capsule may cause nausea and vomiting. It is best to take Pleopill AC-20 mg Capsule with food or with an antacid to avoid nausea and vomiting. If still, you are feeling sick, consult your doctor for the best advice.

Yes, Pleopill AC-20 mg Capsule contains clopidogrel and aspirin that causes blood thinning. It works by preventing platelets (a type of blood cells) from sticking together and forming clots which in turn prevents the risk of heart attack and stroke.

Please consult your doctor if Pleopill AC-20 mg Capsule needs to be stopped before undergoing surgery. The doctor might ask you to stop taking Pleopill AC-20 mg Capsule a few days before surgery to avoid the increased risk of bleeding during the procedure.

Pleopill AC-20 mg Capsule is generally safe to take for a long time. In fact, it works best if you take it for many months or even years. If you&amp;#039;re at risk of getting a stomach ulcer, your doctor may prescribe a medicine to help protect your stomach while you&amp;#039;re taking Pleopill AC-20 mg Capsule .

Yes, the use of Pleopill AC-20 mg Capsule can cause dizziness (feeling sleepy, tired). If you feel dizzy, inform your doctor and do as advised.

Yes, taking Pleopill AC-20 mg Capsule can increase the risk of bleeding as it contains aspirin and clopidogrel which belongs to a class of blood-thinning agents. So, please be very cautious while shaving, cutting fingernails or toenails, or using sharp objects to avoid any bleeding. Let your doctor know before going any surgical procedure, that you are taking Pleopill AC-20 mg Capsule .

Prolonged use of Pleopill AC-20 mg Capsule may cause muscle diseases like myopathy and rhabdomyolysis. So if you feel any musculoskeletal pain after taking Pleopill AC-20 mg Capsule consult your doctor about this issue.

Try not to stop taking this medicine of your own. Stopping Pleopill AC-20 mg Capsule abruptly may worsen your condition and increase your risk of a future heart attack. If you are facing any difficulty while taking this, consult your doctor.

A low-cholesterol diet, along with a regular exercise regime, is recommended.

Components in Pleopill AC-20 mg Capsule , such as Clopidogrel and Aspirin, are blood thinners.

Store in a cool and dry place away from sunlight. Keep out of the sight and reach of children.

Yes, Pleopill AC-20 mg Capsule can be taken with meals.

Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimise side effects.

Take the missed dose as soon as you remember unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

To treat your condition effectually, continue taking Pleopill AC-20 mg Capsule for as long as recommended. Feel free to speak with your doctor if you experience any difficulty while taking Pleopill AC-20 mg Capsule .

Do not take other medicines when you take Pleopill AC-20 mg Capsule unless you have discussed them with your doctor. Your doctor will check for potential interactions before prescribing them.

Grapefruit juice may lower Pleopill AC-20 mg Capsule levels in the body. This could make Pleopill AC-20 mg Capsule less effective.

You may need to take Pleopill AC-20 mg Capsule for a few weeks or months, or you may have to take it for the rest of your life. Inform your doctor if you face any difficulty while using it.

Consumption of alcohol should be limited or avoided. Drinking too much alcohol while you're taking Pleopill AC-20 mg Capsule can irritate your stomach. There's a risk that you could get a stomach ulcer.

Common side effects of Pleopill AC-20 mg Capsule may include headaches, dizziness, ankle swelling (oedema), slow heart rate, diarrhoea, and nausea. Most of these side effects of Pleopill AC-20 mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Country of origin

India

Manufacturer/Marketer address

249, T.V.Samy Road [east], Near Hotel Navaratna, R.S.Puram, Coimbatore-641002, Tamil Nadu, India
Other Info - PLE0100

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