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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Pobix 750000IU Injection 1's is used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. It contains Polymyxin B, which destroys bacterial cell membranes and kills infection-causing bacteria. Thereby, it helps treat bacterial infections. In some cases, Pobix 750000IU Injection 1's may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea.

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Manufacturer/Marketer :

Concord Biotech Ltd

Consume Type :

Parenteral

Expires on or after :

Return Policy :

Not Returnable

About Pobix 750000IU Injection 1's

Pobix 750000IU Injection 1's belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms.

Pobix 750000IU Injection 1's contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

In some cases, Pobix 750000IU Injection 1's may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Let the doctor know if you are allergic to any of the components in Pobix 750000IU Injection 1's. Consult the doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Pobix 750000IU Injection 1's

Pobix 750000IU Injection 1's is used in the treatment of Bacterial infections. The detailed uses of Pobix 750000IU Injection 1's are as follows:

  • Treat bloodstream infections: Pobix 750000IU Injection 1's is effective against septicemia caused by resistant gram-negative bacteria such as Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli.
  • Manage meningitis: Pobix 750000IU Injection 1's is administered intrathecally to treat bacterial meningitis, especially when caused by Pseudomonas aeruginosa or Haemophilus influenzae.
  • Treat urinary tract infections: Pobix 750000IU Injection 1's helps eliminate gram-negative pathogens in complicated or hospital-acquired UTIs.
  • Address pulmonary infections: Pobix 750000IU Injection 1's is used in cases of pneumonia and pulmonary embolism caused by multidrug-resistant gram-negative bacteria.

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Directions for Use

  • Pobix 750000IU Injection 1's will be administered by a healthcare professional.
  • Do not self-administer it.

Key Benefits

Pobix 750000IU Injection 1's belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. Pobix 750000IU Injection 1's contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

How Pobix 750000IU Injection 1's Works

Pobix 750000IU Injection 1's contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Pobix 750000IU Injection 1's

As Pobix 750000IU Injection 1's is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not receive Pobix 750000IU Injection 1's if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. Seek medical attention if you experience symptoms of kidney problems (unable to pass urine, change in how much urine you pass), nerve problems (weakness, irritation, feeling sleepy, blurred eyesight, change in balance, numbness or tingling around the mouth or in the arms or legs, or trouble breathing), or Clostridium difficile associated diarrhoea/CDAD (stomach pain, cramps, very loose, watery, or bloody stool). Let the doctor know if you are taking any prescription/non-prescription medicines, including supplements or herbal products.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Pobix 750000IU Injection:
Co-administration of Pobix 750000IU Injection may increase the effects of Suxamethonium when taken in combination.

How to manage the interaction:
Co-administration of Suxamethonium with Pobix 750000IU Injection can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Pobix 750000IU Injection:
When Neomycin and Pobix 750000IU Injection are taken together, there is an increased possibility of severe side effects.

How to manage the interaction:
Taking Pobix 750000IU Injection with Neomycin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bBCG vaccine
Severe
How does the drug interact with Pobix 750000IU Injection:
When the BCG vaccine is used with Pobix 750000IU Injection, its effectiveness may be reduced.

How to manage the interaction:
There may be a possibility of interaction between Pobix 750000IU Injection and BCG vaccine, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pobix 750000IU Injection:
Co-administration of Pobix 750000IU Injection with Atracurium may cause serious breathing problems

How to manage the interaction:
There may be a possibility of interaction between Pobix 750000IU Injection and Atracurium, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without a doctor's advice.
Polymyxin bCholera, live attenuated
Severe
How does the drug interact with Pobix 750000IU Injection:
Taking Pobix 750000IU Injection and Cholera together may lead to a decrease in the effectiveness of the vaccine.

How to manage the interaction:
There may be a possibility of interaction between Pobix 750000IU Injection and Cholera, live attenuated, but it can be taken if prescribed by a doctor. It is advised not to receive the cholera vaccination until at least 14 days after finishing your Pobix 750000IU Injection therapy in order to ensure an appropriate immune response. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Pobix 750000IU Injection:
Taking Pobix 750000IU Injection with Pancuronium together can cause breathing problems.

How to manage the interaction:
Taking Pobix 750000IU Injection with Pancuronium together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any breathing problems, consult a doctor. Do not discontinue any medications without consulting a doctor.
Polymyxin bTubocurarine
Severe
How does the drug interact with Pobix 750000IU Injection:
Co-administration of Pobix 750000IU Injection and Tubocurarine together may cause serious breathing problems.

How to manage the interaction:
There may be a possibility of interaction between Pobix 750000IU Injection and Tubocurarine, but it can be taken if prescribed by a doctor. However, if you experience any breathing difficulty, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Pobix 750000IU Injection:
Using Pobix 750000IU Injection together with streptomycin can increase the risk or severity of developing hearing loss, breathing problems, and kidney problems.

How to manage the interaction:
Although taking Pobix 750000IU Injection and Streptomycin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Pobix 750000IU Injection:
Co-administration of Deferasirox and Pobix 750000IU Injection may increase the risk of kidney problems.

How to manage the interaction:
Although taking Pobix 750000IU Injection and Deferasirox together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, swelling, breathing difficulty, bone pain, muscle pain, dizziness, confusion, or irregular heart rhythm, seek immediate medical attention. Drink plenty of water if you experience diarrhea or vomiting while taking these medications, as dehydration can potentially affect the kidneys. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Pobix 750000IU Injection:
Taking Human immunoglobulin with Polymyxin- b, may raise the risk of kidney problems.

How to manage the interaction:
Although taking Human immunoglobulin and Pobix 750000IU Injection together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include whole grains, fruits, and vegetables in your diet. 
  • Taking probiotics after antibiotic treatment and eating high-fibre and prebiotic foods may help reduce side effects and support digestion.
  • Exercising regularly helps in improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress.
  • Avoid processed and fried food.

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

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Alcohol

Consult your doctor

It is not known if alcohol interacts with Pobix 750000IU Injection 1's. Please consult the doctor.

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Pregnancy

Caution

The safety of polymyxin B in pregnancy has not been established. If you are pregnant or planning pregnancy, inform the doctor before receiving Pobix 750000IU Injection 1's.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Pobix 750000IU Injection 1's. Caution is advised while administering Pobix 750000IU Injection 1's to lactating women.

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Driving

Consult your doctor

It is unknown if Pobix 750000IU Injection 1's affects your ability to drive. Drive only if you are alert.

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Liver

Consult your doctor

If you have a history of liver problems, inform the doctor before receiving Pobix 750000IU Injection 1's.

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Kidney

Caution

If you have a history of kidney problems, inform the doctor before receiving Pobix 750000IU Injection 1's.

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Children

Safe if prescribed

Pobix 750000IU Injection 1's may be safe for use in children if prescribed by the doctor.

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Heart

Pobix 750000IU Injection 1's can be used in heart patients, but only with close medical supervision due to risks like kidney damage and neurotoxicity. Your doctor will assess your overall health and monitor you carefully throughout treatment.

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Geriatrics

Caution

Geriatric patients can receive Pobix 750000IU Injection 1's, but with extra caution. Since kidney function often declines with age, doctors must monitor renal health closely and adjust the dosage accordingly.

FAQs

Pobix 750000IU Injection 1's is used to treat Bacterial infections.

Pobix 750000IU Injection 1's works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Diarrhoea might be a side effect of Pobix 750000IU Injection 1's. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult the doctor if the condition persists or worsens.

Pobix 750000IU Injection 1's may cause nerve problems. Consult the doctor if you experience weakness, irritation, change in balance, feeling sleepy, blurred eyesight, trouble breathing, numbness or tingling sensation in the arms and legs.

Pobix 750000IU Injection 1's will be administered by a healthcare professional. Do not self-administer.

Yes, Pobix 750000IU Injection 1's is safe when used only under the doctor’s supervision. However, it may cause pain at the injection site, flushing, dizziness, and diarrhoea while using it.

The common side effects of Pobix 750000IU Injection 1's may include pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

16Th Floor, B-Wing, Mondeal Heights, Iscon Cross Road, S.G. Highway, Ahmedabad 380015, Gujarat, India.
Other Info - POB0003

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