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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Poly-B 500000IU Injection is used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. It contains Polymyxin B, which destroys bacterial cell membranes and kills infection-causing bacteria. Thereby, it helps treat bacterial infections. In some cases, Poly-B 500000IU Injection may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea.

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Whats That

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Synonym :

POLYMYXIN B SULPHATE

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Poly-B 500000IU Injection

Poly-B 500000IU Injection belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms.

Poly-B 500000IU Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

In some cases, Poly-B 500000IU Injection may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Let the doctor know if you are allergic to any of the components in Poly-B 500000IU Injection. Consult the doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Poly-B 500000IU Injection

Treatment of Bacterial infections

Directions for Use

Poly-B 500000IU Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Poly-B 500000IU Injection belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. Poly-B 500000IU Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

How Poly-B 500000IU Injection Works

Poly-B 500000IU Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Poly-B 500000IU Injection

As Poly-B 500000IU Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not receive Poly-B 500000IU Injection if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. Seek medical attention if you experience symptoms of kidney problems (unable to pass urine, change in how much urine you pass), nerve problems (weakness, irritation, feeling sleepy, blurred eyesight, change in balance, numbness or tingling around the mouth or in the arms or legs, or trouble breathing), or Clostridium difficile associated diarrhoea/CDAD (stomach pain, cramps, very loose, watery, or bloody stool). Let the doctor know if you are taking any prescription/non-prescription medicines, including supplements or herbal products.

Drug-Drug Interactions

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Polymyxin bAmikacin
Severe
Polymyxin bBCG vaccine
Severe

Drug-Drug Interactions

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Polymyxin bAmikacin
Severe
How does the drug interact with Poly-B 500000IU Injection:
Coadministration of Amikacin with Poly-B 500000IU Injection may increase the risk of severe side effects.

How to manage the interaction:
Although taking Amikacin and Polymyxin- b together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience ringing in the ears, difficulty breathing, vomiting, irregular urination, swelling, muscle pain, dizziness, or palpitation. Do not stop using any medications without talking to a doctor.
Polymyxin bBCG vaccine
Severe
How does the drug interact with Poly-B 500000IU Injection:
When the BCG vaccine is used with Poly-B 500000IU Injection, its effectiveness may be reduced.

How to manage the interaction:
There may be a possibility of interaction between Poly-B 500000IU Injection and BCG vaccine, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
Polymyxin bNeomycin
Severe
How does the drug interact with Poly-B 500000IU Injection:
When Neomycin and Poly-B 500000IU Injection are taken together, there is an increased possibility of severe side effects.

How to manage the interaction:
Taking Poly-B 500000IU Injection with Neomycin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bSuxamethonium
Severe
How does the drug interact with Poly-B 500000IU Injection:
Co-administration of Poly-B 500000IU Injection may increase the effects of Suxamethonium when taken in combination.

How to manage the interaction:
Co-administration of Suxamethonium with Poly-B 500000IU Injection can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
Polymyxin bNetilmicin
Severe
How does the drug interact with Poly-B 500000IU Injection:
Co-administration of Netilmicin with Poly-B 500000IU Injection can increase the risk of side effects.

How to manage the interaction:
Co-administration of Netilmicin with Poly-B 500000IU Injection can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bTobramycin
Severe
How does the drug interact with Poly-B 500000IU Injection:
Taking Tobramycin with Poly-B 500000IU Injection can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Tobramycin and Poly-B 500000IU Injection, you can take these medicines together if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, difficulty breathing, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Polymyxin bCidofovir
Severe
How does the drug interact with Poly-B 500000IU Injection:
Taking Cidofovir with Poly-B 500000IU Injection sulfate can increase the risk of kidney problems.

How to manage the interaction:
Although taking Polymyxin-b and Cidofovir together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, swelling, breathing difficulty, bone pain, muscle pain, dizziness, confusion, or irregular heart rhythm, consult a doctor. Do not stop using any medications without talking to a doctor.
Polymyxin bTenofovir alafenamide
Severe
How does the drug interact with Poly-B 500000IU Injection:
Taking Tenofovir alafenamide with Poly-B 500000IU Injection can increase the chance of side effects.

How to manage the interaction:
Taking Tenofovir alafenamide with Poly-B 500000IU Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bTacrolimus
Severe
How does the drug interact with Poly-B 500000IU Injection:
Taking Tacrolimus with Poly-B 500000IU Injection may increase the risk of kidney problems.

How to manage the interaction:
Although taking tacrolimus and Poly-B 500000IU Injection together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, muscle pain, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Polymyxin bAtracurium
Severe
How does the drug interact with Poly-B 500000IU Injection:
Co-administration of Poly-B 500000IU Injection with Atracurium may cause serious breathing problems

How to manage the interaction:
There may be a possibility of interaction between Poly-B 500000IU Injection and Atracurium, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include whole grains, fruits, and vegetables in your diet. 
  • Taking probiotics after antibiotic treatment and eating high-fibre and prebiotic foods may help reduce side effects and support digestion.
  • Exercising regularly helps in improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress.
  • Avoid processed and fried food.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Poly-B 500000IU Injection Substitute

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Alcohol

Consult your doctor

It is not known if alcohol interacts with Poly-B 500000IU Injection. Please consult the doctor.

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Pregnancy

Caution

The safety of polymyxin B in pregnancy has not been established. If you are pregnant or planning pregnancy, inform the doctor before receiving Poly-B 500000IU Injection.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Poly-B 500000IU Injection. Caution is advised while administering Poly-B 500000IU Injection to lactating women.

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Driving

Consult your doctor

It is unknown if Poly-B 500000IU Injection affects your ability to drive. Drive only if you are alert.

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Liver

Consult your doctor

If you have a history of liver problems, inform the doctor before receiving Poly-B 500000IU Injection.

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Kidney

Caution

If you have a history of kidney problems, inform the doctor before receiving Poly-B 500000IU Injection.

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Children

Safe if prescribed

Poly-B 500000IU Injection may be safe for use in children if prescribed by the doctor.

FAQs

Poly-B 500000IU Injection is used to treat Bacterial infections.

Poly-B 500000IU Injection works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Diarrhoea might be a side effect of Poly-B 500000IU Injection. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult the doctor if the condition persists or worsens.

Poly-B 500000IU Injection may cause nerve problems. Consult the doctor if you experience weakness, irritation, change in balance, feeling sleepy, blurred eyesight, trouble breathing, numbness or tingling sensation in the arms and legs.

Poly-B 500000IU Injection will be administered by a healthcare professional. Do not self-administer.

Yes, Poly-B 500000IU Injection is safe when used only under the doctor’s supervision. However, it may cause pain at the injection site, flushing, dizziness, and diarrhoea while using it.

The common side effects of Poly-B 500000IU Injection may include pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Country of origin

INDIA

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - POL0010

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