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compositionComposition:POLYMYXIN B-750000UNITS
prescriptionPrescription Medicine
Polynex Injection 1's
Polynex Injection 1's

Polynex Injection is used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. It contains Polymyxin B, which destroys bacterial cell membranes and kills infection-causing bacteria. Thereby, it helps treat bacterial infections. In some cases, Polynex Injection may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

POLYMYXIN B-750000UNITS

Manufacturer/Marketer :

Zymes Bioscience Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Polynex Injection

Polynex Injection belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms.

Polynex Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

In some cases, Polynex Injection may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Let the doctor know if you are allergic to any of the components in Polynex Injection. Consult the doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Polynex Injection

Polynex Injection is used in the treatment of Bacterial infections. The detailed uses of Polynex Injection are as follows:

  • Treat bloodstream infections: Polynex Injection is effective against septicemia caused by resistant gram-negative bacteria such as Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli.
  • Manage meningitis: Polynex Injection is administered intrathecally to treat bacterial meningitis, especially when caused by Pseudomonas aeruginosa or Haemophilus influenzae.
  • Treat urinary tract infections: Polynex Injection helps eliminate gram-negative pathogens in complicated or hospital-acquired UTIs.
  • Address pulmonary infections: Polynex Injection is used in cases of pneumonia and pulmonary embolism caused by multidrug-resistant gram-negative bacteria.

Key Benefits

Polynex Injection belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. Polynex Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Directions for Use

  • Polynex Injection will be administered by a healthcare professional.
  • Do not self-administer it.

How Polynex Injection Works

Polynex Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Polynex Injection. Please consult the doctor.

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Pregnancy

Caution

The safety of polymyxin B in pregnancy has not been established. If you are pregnant or planning pregnancy, inform the doctor before receiving Polynex Injection.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Polynex Injection. Caution is advised while administering Polynex Injection to lactating women.

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Driving

Consult your doctor

It is unknown if Polynex Injection affects your ability to drive. Drive only if you are alert.

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Liver

Consult your doctor

If you have a history of liver problems, inform the doctor before receiving Polynex Injection.

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Kidney

Caution

If you have a history of kidney problems, inform the doctor before receiving Polynex Injection.

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Children

Safe if prescribed

Polynex Injection may be safe for use in children if prescribed by the doctor.

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Heart

Caution

Polynex Injection can be used in heart patients, but only with close medical supervision due to risks like kidney damage and neurotoxicity. Your doctor will assess your overall health and monitor you carefully throughout treatment.

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Geriatrics

Caution

Geriatric patients can receive Polynex Injection, but with extra caution. Since kidney function often declines with age, doctors must monitor renal health closely and adjust the dosage accordingly.

What if I have taken an overdose of Polynex Injection

As Polynex Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Diet & Lifestyle Advise

  • Include whole grains, fruits, and vegetables in your diet. 
  • Taking probiotics after antibiotic treatment and eating high-fibre and prebiotic foods may help reduce side effects and support digestion.
  • Exercising regularly helps in improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress.
  • Avoid processed and fried food.

Have a query?

Drug Warnings

Do not receive Polynex Injection if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. Seek medical attention if you experience symptoms of kidney problems (unable to pass urine, change in how much urine you pass), nerve problems (weakness, irritation, feeling sleepy, blurred eyesight, change in balance, numbness or tingling around the mouth or in the arms or legs, or trouble breathing), or Clostridium difficile associated diarrhoea/CDAD (stomach pain, cramps, very loose, watery, or bloody stool). Let the doctor know if you are taking any prescription/non-prescription medicines, including supplements or herbal products.

Drug-Drug Interactions

verifiedApollotooltip
Polymyxin bTubocurarine
Severe
Polymyxin bKanamycin
Severe

Drug-Drug Interactions

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Polymyxin bTubocurarine
Severe
How does the drug interact with Polynex Injection:
Co-administration of Polynex Injection and Tubocurarine together may cause serious breathing problems.

How to manage the interaction:
There may be a possibility of interaction between Polynex Injection and Tubocurarine, but it can be taken if prescribed by a doctor. However, if you experience any breathing difficulty, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Polymyxin bKanamycin
Severe
How does the drug interact with Polynex Injection:
Taking Kanamycin with Polynex Injection can increase the risk and severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Polynex Injection and Kanamycin, but it can be taken if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, vertigo, difficulty breathing, nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bTenofovir alafenamide
Severe
How does the drug interact with Polynex Injection:
Taking Tenofovir alafenamide with Polynex Injection can increase the chance of side effects.

How to manage the interaction:
Taking Tenofovir alafenamide with Polynex Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bNeomycin
Severe
How does the drug interact with Polynex Injection:
When Neomycin and Polynex Injection are taken together, there is an increased possibility of severe side effects.

How to manage the interaction:
Taking Polynex Injection with Neomycin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bAdefovir dipivoxil
Severe
How does the drug interact with Polynex Injection:
Taking Adefovir dipivoxil with Polynex Injection may increase the risk of side effects.

How to manage the interaction:
Although taking Polynex Injection and Adefovir dipivoxil together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, decreased hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bIodamide
Severe
How does the drug interact with Polynex Injection:
Co-administration of Iodamide with Polynex Injection may increase the risk of kidney damage.

How to manage the interaction:
Although there is a possible interaction between Polynex Injection and Iodamide, you can take these medicines together if prescribed by a doctor. However, contact a doctor immediately if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, muscle pain, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Polymyxin bDeferasirox
Severe
How does the drug interact with Polynex Injection:
Co-administration of Deferasirox and Polynex Injection may increase the risk of kidney problems.

How to manage the interaction:
Although taking Polynex Injection and Deferasirox together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, swelling, breathing difficulty, bone pain, muscle pain, dizziness, confusion, or irregular heart rhythm, seek immediate medical attention. Drink plenty of water if you experience diarrhea or vomiting while taking these medications, as dehydration can potentially affect the kidneys. Do not discontinue any medications without a doctor's advice.
Polymyxin bSirolimus
Severe
How does the drug interact with Polynex Injection:
Co-administration of Sirolimus and Polynex Injection together may increase the risk or severity of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Sirolimus and Polynex Injection, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bNetilmicin
Severe
How does the drug interact with Polynex Injection:
Co-administration of Netilmicin with Polynex Injection can increase the risk of side effects.

How to manage the interaction:
Co-administration of Netilmicin with Polynex Injection can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bTobramycin
Severe
How does the drug interact with Polynex Injection:
Taking Tobramycin with Polynex Injection can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Tobramycin and Polynex Injection, you can take these medicines together if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, difficulty breathing, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Polynex Injection is used to treat Bacterial infections.

Polynex Injection works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Diarrhoea might be a side effect of Polynex Injection. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult the doctor if the condition persists or worsens.

Polynex Injection may cause nerve problems. Consult the doctor if you experience weakness, irritation, change in balance, feeling sleepy, blurred eyesight, trouble breathing, numbness or tingling sensation in the arms and legs.

Polynex Injection will be administered by a healthcare professional. Do not self-administer.

Yes, Polynex Injection is safe when used only under the doctor’s supervision. However, it may cause pain at the injection site, flushing, dizziness, and diarrhoea while using it.

The common side effects of Polynex Injection may include pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

Scf-309, Main Market And Commercials,Mani Majra Chandigarh - 106101
Other Info - POL0457

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