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compositionComposition:POLYMYXIN B-750000IU
prescription
Prescription Medicine
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Polypure-XP 750000 IU Injection 1's is used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. It contains Polymyxin B, which destroys bacterial cell membranes and kills infection-causing bacteria. Thereby, it helps treat bacterial infections. In some cases, Polypure-XP 750000 IU Injection 1's may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

POLYMYXIN B-750000IU

Manufacturer/Marketer :

Alniche Life Sciences Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Polypure-XP 750000 IU Injection 1's

Polypure-XP 750000 IU Injection 1's is an injectable medicine used to treat severe and serious bacterial infections, especially those caused by specific hard-to-treat bacteria. It is typically prescribed when other standard antibiotics are not working or cannot be used. Doctors commonly use this medicine to treat serious infections of the blood, urinary tract, or brain.

Because Polypure-XP 750000 IU Injection 1's is given as an injection or infusion, a healthcare professional will give it to you in a hospital or clinic setting. It is highly important to receive this medicine at regular, scheduled intervals to keep a steady level of the medicine in your body. Drinking plenty of water during your treatment helps support your kidneys while you receive this therapy.

While receiving Polypure-XP 750000 IU Injection 1's, you may experience mild side effects such as temporary dizziness, drowsiness, or mild irritation at the injection site. However, you must inform your healthcare provider immediately if you experience serious side effects like numbness, tingling in your hands or feet, decreased urination, or breathing difficulties.

Before starting treatment, tell your doctor if you have kidney disease, neuromuscular disorders like myasthenia gravis, or a history of allergies to similar medicines. Do not receive this medicine if you have had a severe allergic reaction to it or its components in the past.

This medicine can interact with other drugs that affect your kidneys or nervous system, which can increase your risk of side effects. It is important to avoid alcohol during treatment, as it can worsen dizziness and strain your body. If you are pregnant, breastfeeding, or an older adult, consult your doctor to discuss the risks and benefits before starting therapy.

Uses of Polypure-XP 750000 IU Injection 1's

Polypure-XP 750000 IU Injection 1's is used to treat severe and serious bacterial infections. The detailed uses of Polypure-XP 750000 IU Injection 1's are as follows:

  • Severe bloodstream infections: Helps eliminate dangerous bacteria circulating in the blood, supporting your body's recovery from severe illness.
  • Serious urinary tract infections: Targets and clears deep-seated bacterial infections in the bladder or kidneys when standard treatments fail to work.
  • Meningitis: Injected directly into the spinal fluid in certain cases to clear life-threatening bacterial infections affecting the brain and spinal cord.
  • Severe lung infections: Assists in clearing difficult, resistant bacterial infections in the respiratory tract.

Key Benefits

Polypure-XP 750000 IU Injection 1's helps treat serious bacterial infections, including infections caused by bacteria that may not respond to many other antibiotics. By eliminating the bacteria responsible for the infection, it supports recovery and helps prevent the infection from spreading.

  • Treats Severe Bacterial Infections: By targeting and killing susceptible bacteria, Polypure-XP 750000 IU Injection 1's helps control serious infections and supports the healing of the affected organs and tissues.
  • Helps Reduce Infection Symptoms: As the infection improves, Polypure-XP 750000 IU Injection 1's helps relieve symptoms such as fever, body aches, weakness, and fatigue, allowing you to gradually regain strength.
  • Supports Recovery and Prevents Complications: Effective treatment helps reduce the risk of the infection spreading further or causing long-term complications, supporting a safer and more complete recovery when used as prescribed.

Directions for Use

  • Polypure-XP 750000 IU Injection 1's will be administered by a healthcare professional.
  • Do not self-administer it.

How Polypure-XP 750000 IU Injection 1's Works

Polypure-XP 750000 IU Injection 1's contains polymyxin B, which works by targeting the protective outer layer, or membrane, of specific types of bacteria. It binds directly to this outer barrier and disrupts its structure, making it leaky. This disruption causes the vital contents of the bacterial cell to escape, which rapidly kills the bacteria and stops the infection from spreading. Because of this unique way of damaging the bacterial cell membrane, this medicine is highly effective against bacteria that have developed resistance to other traditional antibiotics. This ensures that even tough, hard-to-treat infections can be brought under control quickly and effectively.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Polypure-XP 750000 IU Injection 1's. Please consult the doctor.

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Pregnancy

Caution

The safety of polymyxin B in pregnancy has not been established. If you are pregnant or planning pregnancy, inform the doctor before receiving Polypure-XP 750000 IU Injection 1's.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Polypure-XP 750000 IU Injection 1's. Caution is advised while administering Polypure-XP 750000 IU Injection 1's to lactating women.

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Driving

Consult your doctor

It is unknown if Polypure-XP 750000 IU Injection 1's affects your ability to drive. Drive only if you are alert.

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Liver

Consult your doctor

If you have a history of liver problems, inform the doctor before receiving Polypure-XP 750000 IU Injection 1's.

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Kidney

Caution

If you have a history of kidney problems, inform the doctor before receiving Polypure-XP 750000 IU Injection 1's.

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Children

Safe if prescribed

Polypure-XP 750000 IU Injection 1's may be safe for use in children if prescribed by the doctor.

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Heart

Caution

Polypure-XP 750000 IU Injection 1's can be used in heart patients, but only with close medical supervision due to risks like kidney damage and neurotoxicity. Your doctor will assess your overall health and monitor you carefully throughout treatment.

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Geriatrics

Caution

Geriatric patients can receive Polypure-XP 750000 IU Injection 1's, but with extra caution. Since kidney function often declines with age, doctors must monitor renal health closely and adjust the dosage accordingly.

What if I have taken an overdose of Polypure-XP 750000 IU Injection 1's

An overdose of this medicine is rare because it is given under close medical supervision. However, if you suspect an overdose or experience sudden severe symptoms like extreme muscle weakness, numbness, or breathing trouble, seek emergency medical attention right away.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water throughout the day (unless advised otherwise by your doctor) to help your kidneys flush out the medicine and reduce the risk of kidney strain.
  • Rest and recover: Allow your body ample time to rest, as fighting off a severe bacterial infection requires a significant amount of energy.
  • Eat a balanced diet: Focus on nutrient-rich foods to support your immune system during recovery, but consult your healthcare team if you need to limit protein due to kidney function.
  • Avoid kidney-straining substances: Limit or avoid over-the-counter pain relievers (like ibuprofen or naproxen) and alcohol, as these can add stress to your kidneys while you are on this medicine.
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How Soon It Starts Working

The time required for Polypure-XP 750000 IU Injection 1's to start to work: Polypure-XP 750000 IU Injection 1's ideally shows its action within 2 hours after administration. The time for which the effects of Polypure-XP 750000 IU Injection 1's last: The effect of Polypure-XP 750000 IU Injection 1's lasts for 6 hours.

What if you forget to take Polypure-XP 750000 IU Injection 1's

Since this medicine is given by a healthcare provider in a hospital or clinic, missing a dose is unlikely. However, if you miss an appointment or suspect a dose was missed, contact your healthcare provider immediately to reschedule. Do not try to double the dose to catch up.

Storage

• Unopened vials of Polypure-XP 750000 IU Injection 1's powder for injection should be stored at controlled room temperature, ideally between 20°C to 25°C (68°F to 77°F).

Drug Warnings

  • Inspect the solution: Before injection, ensure the liquid is clear and free from any floating particles or unusual discolouration.
  • Monitor kidney function: Attend all scheduled blood and urine tests so your doctor can regularly check your kidney health during treatment.
  • Rotate injection sites: If you are receiving this medicine as an injection into the muscle, make sure the injection site is rotated each time to prevent tissue irritation.
  • Watch for nerve symptoms: Report any face numbness, tingling, or dizzy spells immediately, as these can be early signs of nerve sensitivity.
  • Complete the full course: Even if you start feeling better quickly, ensure you receive the full duration of therapy prescribed by your doctor to prevent the infection from returning.

Drug-Drug Interactions

verifiedApollotooltip

  • Nephrotoxic medicines (e.g., aminoglycoside antibiotics such as gentamicin or certain diuretics): Taking these medicines together may increase the risk of kidney damage and, in some cases, nerve-related side effects. Your doctor may recommend closer monitoring of kidney function during treatment.
  • Neuromuscular blocking agents (used during surgery, e.g., vecuronium and rocuronium): This medicine may enhance the effects of these medicines, increasing the risk of prolonged muscle weakness and severe breathing difficulties. Inform your surgeon or anaesthetist if you are taking this medicine before any surgical procedure.
Polymyxin bAmikacin
Severe
Polymyxin bPancuronium
Severe

Drug-Drug Interactions

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Polymyxin bAmikacin
Severe
How does the drug interact with Polypure-XP 750000 IU Injection:
Coadministration of Amikacin with Polypure-XP 750000 IU Injection may increase the risk of severe side effects.

How to manage the interaction:
Although taking Amikacin and Polymyxin- b together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience ringing in the ears, difficulty breathing, vomiting, irregular urination, swelling, muscle pain, dizziness, or palpitation. Do not stop using any medications without talking to a doctor.
Polymyxin bPancuronium
Severe
How does the drug interact with Polypure-XP 750000 IU Injection:
Taking Polypure-XP 750000 IU Injection with Pancuronium together can cause breathing problems.

How to manage the interaction:
Taking Polypure-XP 750000 IU Injection with Pancuronium together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any breathing problems, consult a doctor. Do not discontinue any medications without consulting a doctor.
Polymyxin bTacrolimus
Severe
How does the drug interact with Polypure-XP 750000 IU Injection:
Taking Tacrolimus with Polypure-XP 750000 IU Injection may increase the risk of kidney problems.

How to manage the interaction:
Although taking tacrolimus and Polypure-XP 750000 IU Injection together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, muscle pain, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Polymyxin bAtracurium
Severe
How does the drug interact with Polypure-XP 750000 IU Injection:
Co-administration of Polypure-XP 750000 IU Injection with Atracurium may cause serious breathing problems

How to manage the interaction:
There may be a possibility of interaction between Polypure-XP 750000 IU Injection and Atracurium, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without a doctor's advice.
Polymyxin bCholera, live attenuated
Severe
How does the drug interact with Polypure-XP 750000 IU Injection:
Taking Polypure-XP 750000 IU Injection and Cholera together may lead to a decrease in the effectiveness of the vaccine.

How to manage the interaction:
There may be a possibility of interaction between Polypure-XP 750000 IU Injection and Cholera, live attenuated, but it can be taken if prescribed by a doctor. It is advised not to receive the cholera vaccination until at least 14 days after finishing your Polypure-XP 750000 IU Injection therapy in order to ensure an appropriate immune response. Do not discontinue any medications without a doctor's advice.
Polymyxin bTobramycin
Severe
How does the drug interact with Polypure-XP 750000 IU Injection:
Taking Tobramycin with Polypure-XP 750000 IU Injection can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Tobramycin and Polypure-XP 750000 IU Injection, you can take these medicines together if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, difficulty breathing, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Polymyxin bTubocurarine
Severe
How does the drug interact with Polypure-XP 750000 IU Injection:
Co-administration of Polypure-XP 750000 IU Injection and Tubocurarine together may cause serious breathing problems.

How to manage the interaction:
There may be a possibility of interaction between Polypure-XP 750000 IU Injection and Tubocurarine, but it can be taken if prescribed by a doctor. However, if you experience any breathing difficulty, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Polymyxin bIodamide
Severe
How does the drug interact with Polypure-XP 750000 IU Injection:
Co-administration of Iodamide with Polypure-XP 750000 IU Injection may increase the risk of kidney damage.

How to manage the interaction:
Although there is a possible interaction between Polypure-XP 750000 IU Injection and Iodamide, you can take these medicines together if prescribed by a doctor. However, contact a doctor immediately if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, muscle pain, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Polymyxin bAdefovir dipivoxil
Severe
How does the drug interact with Polypure-XP 750000 IU Injection:
Taking Adefovir dipivoxil with Polypure-XP 750000 IU Injection may increase the risk of side effects.

How to manage the interaction:
Although taking Polypure-XP 750000 IU Injection and Adefovir dipivoxil together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, decreased hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bSuxamethonium
Severe
How does the drug interact with Polypure-XP 750000 IU Injection:
Co-administration of Polypure-XP 750000 IU Injection may increase the effects of Suxamethonium when taken in combination.

How to manage the interaction:
Co-administration of Suxamethonium with Polypure-XP 750000 IU Injection can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Polypure-XP 750000 IU Injection 1's when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Polypure-XP 750000 IU Injection 1's may cause nerve-related side effects such as numbness, tingling, weakness, changes in balance, blurred vision, or unusual sensations. Inform your doctor or nurse immediately if you experience numbness, tingling, or other new or worsening nerve-related symptoms.
It is highly recommended to avoid alcohol during your treatment, as it can worsen side effects like dizziness and put extra strain on your kidneys. Talk to your doctor or pharmacist.
Polypure-XP 750000 IU Injection 1's is given as an injection or infusion by a trained healthcare professional, typically into a vein (intravenously), into a muscle, or sometimes directly into the spinal fluid, depending on the infection. Talk to your doctor for details about your specific treatment plan.
This medicine is usually given in a hospital or specialised clinic where healthcare providers can closely monitor your response and safety. In rare cases, receiving the medicine at home may be set up under strict medical supervision. Talk to your doctor to learn more.
This medicine is processed by your kidneys and can sometimes cause strain or kidney damage. Regular blood and urine tests help your doctor monitor your kidney health and adjust your dose if needed. Talk to your doctor if you have any concerns.
Polypure-XP 750000 IU Injection 1's is generally only used during pregnancy or breastfeeding if the benefits outweigh the risks and no safer alternatives are available, as its safety in these groups is not fully established. Talk to your doctor if you are pregnant or nursing.
This medicine can cause side effects like drowsiness, dizziness, and blurred vision, which can impair your ability to drive safely. You should avoid driving or operating machinery until you know how this medicine affects you. Talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

S-14, 2nd Floor, Janta Market Rajouri Garden, New Delhi 110 027
Other Info - POL0586
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