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compositionComposition:POMALIDOMIDE-3MG
prescription
Prescription Medicine
info
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Pomacel 3 mg Capsule 21's is used to treat a type of blood cancer called multiple myeloma in adults 18 years or older. It contains Pomalidomide. Pomalidomide is both a targeted therapy drug and an immunotherapy drug, which works in several different ways. It can help the immune system attack and destroy cancer cells (immune system modulator); it kills or stops cancer cells' growth (cancer growth inhibitor). On the other side, it can block the development of new blood vessels, which cancer cells need to grow and spread (angiogenesis inhibitor).

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

POMALIDOMIDE-3MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Pomacel 3 mg Capsule 21's

Pomacel 3 mg Capsule 21's is a prescription medicine used to treat multiple myeloma (a type of bone marrow cancer) and Kaposi sarcoma (a rare cancer of the blood vessels and skin). It is typically prescribed when other treatments have stopped working, helping to slow down or stop the growth of abnormal cancer cells. By targeting these diseased cells, the medication helps control the progression of the illness.

This medicine is taken in structured cycles, which involve taking the medication daily for a specific number of days followed by a rest period. You should take it at the same time each day, with or without food, by swallowing the capsule whole with water. Drinking plenty of fluids and eating a balanced diet can help your body manage the treatment and support your overall strength.

Common side effects include feeling very tired, low blood cell counts, and constipation. It is vital to contact your doctor immediately if you experience signs of blood clots, such as sudden shortness of breath or pain and swelling in your leg, or signs of a serious infection like a high fever. Your healthcare team will monitor you closely for these issues throughout your treatment.

Do not take this medicine if you are pregnant, planning to become pregnant, or could become pregnant, as it can cause severe, life-threatening birth defects or death to an unborn baby. Pregnancy testing and strict pregnancy prevention measures are required before, during, and after treatment. Before starting, talk to your doctor if you have a history of liver damage, kidney disease, blood clots, or heart problems. This medicine is supplied through a strict pregnancy-prevention and safety programme, and you may be required to complete counselling, pregnancy testing, and regular follow-up before receiving each prescription. 

This medicine can interact with other drugs that cause sleepiness or affect your blood's ability to clot, and smoking can make it less effective. Women who are pregnant or breastfeeding must not take Pomacel 3 mg Capsule 21's, and elderly individuals may need closer monitoring of their kidney function while using it. Talk to your doctor or pharmacist about all other substances you are taking before starting treatment.

Uses of Pomacel 3 mg Capsule 21's

Pomacel 3 mg Capsule 21's is used to treat certain types of cancer. Your doctor may prescribe it for the following conditions:

  • Multiple Myeloma: Pomacel 3 mg Capsule 21's is used to treat adults with this bone marrow cancer, usually in combination with another medicine called dexamethasone, after other cancer therapies have been tried and stopped working. It works by helping the immune system fight the cancer cells and stopping them from growing.
  • Kaposi Sarcoma: This medicine is prescribed for patients with AIDS-related or HIV-negative Kaposi sarcoma when other treatments have not been successful. It helps target and destroy the abnormal cells causing skin and tissue lesions.

Key Benefits

Using Pomacel 3 mg Capsule 21's as prescribed helps control certain cancers and supports your body's ability to fight cancer cells. Here are the key benefits you can expect:

  • Helps control cancer growth: Targets and destroys cancer cells, helping slow disease progression and prolong periods of remission.
  • Supports the immune system: Enhances your body's natural immune response, helping immune cells recognise and attack cancer cells more effectively.
  • Relieves cancer-related symptoms: Helps shrink Kaposi sarcoma lesions and reduce associated pain or swelling. In people with multiple myeloma, controlling the cancer may help reduce bone pain and severe fatigue over time.
Side effects of Pomacel 3 mg Capsule
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.

Directions for Use

  • Pomacel 3 mg Capsule 21's can be taken with or without food.
  • Pomacel 3 mg Capsule 21's is usually taken once a day; however, follow your doctor's advice regarding the dosage and duration.
  • Swallow Pomacel 3 mg Capsule 21's as a whole with a glass of water.
  • Do not break, chew or crush Pomacel 3 mg Capsule 21's.

How Pomacel 3 mg Capsule 21's Works

Pomacel 3 mg Capsule 21's contains pomalidomide, an immunomodulatory medicine that fights cancer in several ways. It helps stop cancer cells from growing and multiplying, causing them to die. It also blocks the formation of new blood vessels that supply nutrients to tumours, which helps slow their growth. In addition, pomalidomide strengthens your body's immune system by increasing the activity of certain white blood cells. This enables the immune system to recognise and destroy abnormal cancer cells more effectively.
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Pomacel 3 mg Capsule 21's.

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Pregnancy

Unsafe

Pomacel 3 mg Capsule 21's should not be taken during pregnancy as it might cause fetal harm. Inform your doctor immediately if you are conceiving while on therapy.

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Breast Feeding

Unsafe

You should not breastfeed when taking Pomacel 3 mg Capsule 21's as it is unknown if the Pomalidomide can pass to your baby in the milk.

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Driving

Caution

This treatment will make you feel very tired. If you feel tired or sleepy, do not drive or use machinery.

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Liver

Caution

Treatment with Pomacel 3 mg Capsule 21's may affect how your liver works. Please inform your doctor before prescribing Pomacel 3 mg Capsule 21's if you have liver impairment. Your doctor will weigh the benefits and potential risks before prescribing Pomacel 3 mg Capsule 21's.

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Kidney

Caution

Treatment with Pomacel 3 mg Capsule 21's may affect how your kidneys work. Please inform your doctor before prescribing Pomacel 3 mg Capsule 21's if you have kidney impairment. Your doctor will weigh the benefits and potential risks before prescribing Pomacel 3 mg Capsule 21's.

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Children

Consult your doctor

It is not known if Pomacel 3 mg Capsule 21's is safe and effective in children.

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Heart

Caution

If you have a history of heart disease, please inform the doctor before receiving Pomacel 3 mg Capsule 21's.

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Geriatrics

Consult your doctor

Limited information available about the use of Pomacel 3 mg Capsule 21's in geriatric patients. Please consult your physician.

What if I have taken an overdose of Pomacel 3 mg Capsule 21's

If you suspect an overdose, seek immediate medical attention right away. Do not wait for symptoms to appear.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water throughout the day. This helps your kidneys flush out waste products as cancer cells are broken down and reduces the risk of severe constipation.
  • Prevent blood clots: Since Pomacel 3 mg Capsule 21's can increase your risk of blood clots, avoid sitting still for long periods. Take short walks, stretch your legs regularly, stay well hydrated, and follow any blood-thinner treatment prescribed by your doctor.
  • Avoid infections: Because this medicine can lower your white blood cell count, wash your hands frequently, avoid close contact with people who are sick, and ensure all food is thoroughly washed and cooked.
  • Protect your skin: If you are being treated for Kaposi sarcoma or experience skin changes, protect your skin from direct sunlight by wearing protective clothing and applying a gentle, broad-spectrum sunscreen.
health query

Have a query?

How Soon It Starts Working

The time required for Pomacel 3 mg Capsule 21's to start to work: The time required for Pomacel 3 mg Capsule 21's to show its action is not clinically established. The time for which the effects of Pomacel 3 mg Capsule 21's last: The duration of action for Pomacel 3 mg Capsule 21's is not clinically established.

What if you forget to take Pomacel 3 mg Capsule 21's

If you miss a dose of Pomacel 3 mg Capsule 21's and it has been less than 12 hours since your scheduled time, take it as soon as you remember. If it has been more than 12 hours, skip the missed dose and take your next dose at your regular scheduled time the next day. Do not take two doses at the same time to make up for a missed one.

Storage

• Store Pomacel 3 mg Capsule 21's at room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Strict pregnancy prevention: You must use two reliable forms of birth control or completely avoid sexual contact during treatment, as this medicine causes severe, permanent birth defects.
  • Never share this medicine: Do not share Pomacel 3 mg Capsule 21's with anyone else, even if they have the same symptoms, as it can be highly toxic to others.
  • Do not donate blood or sperm: Do not donate blood or sperm during treatment and for at least 4 weeks after stopping this medicine. Men taking this medicine should use effective contraception during treatment and for at least 4 weeks after the last dose.
  • Handle with care: If a capsule is damaged, do not touch it directly. Pregnant women should never handle the capsules or packaging of this medicine.
  • Keep up with blood tests: You will need regular blood tests to monitor your blood cell counts and liver function. Do not skip these appointments.

Drug-Drug Interactions

verifiedApollotooltip
  • Strong CYP1A2 inhibitors (such as certain antibiotics like ciprofloxacin): May increase the amount of Pomacel 3 mg Capsule 21's in your blood, raising the risk of severe side effects.
  • Blood thinners or antiplatelet drugs: Combining these with Pomacel 3 mg Capsule 21's can further increase your risk of bleeding, though your doctor may still prescribe a low-dose blood thinner to prevent clots.
PomalidomideBCG vaccine
Critical
PomalidomideDurvalumab
Severe

Drug-Drug Interactions

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PomalidomideBCG vaccine
Critical
How does the drug interact with Pomacel 3 mg Capsule:
Taking the BCG vaccine with Pomacel 3 mg Capsule can increase the risk of infection.

How to manage the interaction:
Taking Pomacel 3 mg Capsule with BCG vaccine is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
PomalidomideDurvalumab
Severe
How does the drug interact with Pomacel 3 mg Capsule:
Taking Pomacel 3 mg Capsule with Durvalumab can increase the risk of developing serious infections.

How to manage the interaction:
Co-administration of Pomacel 3 mg Capsule with Durvalumab can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
PomalidomideCladribine
Severe
How does the drug interact with Pomacel 3 mg Capsule:
Taking Cladribine with Pomacel 3 mg Capsule can increase the risk of infections

How to manage the interaction:
Although taking Cladribine and Pomacel 3 mg Capsule together can cause an interaction, it can be taken if a doctor has suggested it. However, If you experience a fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
PomalidomideAdalimumab
Severe
How does the drug interact with Pomacel 3 mg Capsule:
When Pomacel 3 mg Capsule is taken with Adalimumab, it can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Pomacel 3 mg Capsule and Adalimumab, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
PomalidomideDiethylstilbestrol
Severe
How does the drug interact with Pomacel 3 mg Capsule:
Taking Pomacel 3 mg Capsule with Diethylstilbestrol together can increase the risk of blood clots.

How to manage the interaction:
There may be a possibility of interaction between Pomacel 3 mg Capsule and Diethylstilbestrol, but it can be taken if prescribed by a doctor. However, if you experience chest pain, difficulty breathing, blood in the cough, sudden loss of vision, pain, redness, or swelling in an arm or leg, as well as numbness or weakness on one side of the body, consult a doctor. Do not stop using any medications without talking to a doctor.
PomalidomideNatalizumab
Severe
How does the drug interact with Pomacel 3 mg Capsule:
Taking Pomacel 3 mg Capsule with Natalizumab can increase the likelihood and seriousness of infections.

How to manage the interaction:
Taking Pomacel 3 mg Capsule with Natalizumab together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, progressive weakness on one side of the body, clumsiness of limbs, disturbance of vision, confusion, or changes in thinking, memory, and personality, consult a doctor. Do not discontinue any medications without a doctor's advice.
PomalidomideGolimumab
Severe
How does the drug interact with Pomacel 3 mg Capsule:
When Pomacel 3 mg Capsule is taken with Golimumab, it can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Pomacel 3 mg Capsule and Golimumab together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
PomalidomideDienestrol
Severe
How does the drug interact with Pomacel 3 mg Capsule:
Taking Pomacel 3 mg Capsule with Dienestrol together can increase the risk of blood clots.

How to manage the interaction:
Taking Pomacel 3 mg Capsule with Dienestrol together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain, difficulty breathing, blood in the cough, sudden loss of vision, pain, redness, or swelling in an arm or leg, as well as numbness or weakness on one side of the body, consult a doctor. Do not stop using any medications without talking to a doctor.
PomalidomideToremifene
Severe
How does the drug interact with Pomacel 3 mg Capsule:
When Pomacel 3 mg Capsule is taken with Toremifene, can increase the risk of blood clots.

How to manage the interaction:
Co-administration of Pomacel 3 mg Capsule with Toremifene can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain, difficulty breathing, blood in the cough, sudden loss of vision, pain, redness, or swelling in an arm or leg, as well as numbness or weakness on one side of the body, consult a doctor. Do not stop using any medications without talking to a doctor.
PomalidomideBaricitinib
Severe
How does the drug interact with Pomacel 3 mg Capsule:
Co-administration of Baricitinib and Pomacel 3 mg Capsule can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Pomacel 3 mg Capsule if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Tobacco smoking: Can decrease the effectiveness of Pomacel 3 mg Capsule 21's in your body by speeding up how fast your system processes it.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[IMMUNOMODULATORS]

FAQs

Pomacel 3 mg Capsule 21's is used to treat Multiple myeloma.
Pomacel 3 mg Capsule 21's contains Pomalidomide. Pomalidomide is both a targeted therapy drug and an immunotherapy drug. It works in several different ways. It can help the immune system to attack and destroy cancer cells (immune system modulator); it kills or stops the growth of cancer cells (cancer growth inhibitor). On the other side, it can block the development of new blood vessels, which cancer cells need to grow and spread (angiogenesis inhibitor).
No, it is unsafe to father a child while taking Pomacel 3 mg Capsule 21's. It is recommended for sexually active men to use condoms while on treatment and for at least six months after their last dose of Pomacel 3 mg Capsule 21's.
Pomacel 3 mg Capsule 21's can affect the results of this blood test. Tell the person doing the test that you are using Pomacel 3 mg Capsule 21's.
Based on the medical condition, Pomacel 3 mg Capsule 21's may be given alone or with other medicines used to treat multiple myeloma.
Pomacel 3 mg Capsule 21's can cause a significant decrease in the number of blood cells and platelets. Your doctor may suggest laboratory tests before and during the treatment. Tell your healthcare provider if you develop a fever or have signs of bruising or bleeding.
If you miss the dose of Pomacel 3 mg Capsule 21's, take it as soon as you remember. If it is almost time for the next dose, skip the forgotten dose and go back to your regular schedule. Do not take double the dose to compensate for the forgotten dose.
No, Pomacel 3 mg Capsule 21's is not a steroid. It is a third-generation immunomodulatory drug.
No, you must not take Pomacel 3 mg Capsule 21's if you are pregnant or planning to become pregnant, as it can cause severe birth defects or death to an unborn baby. Talk to your doctor about strict birth control requirements.
Because Pomacel 3 mg Capsule 21's increases the risk of serious blood clots, your doctor will likely prescribe a daily blood thinner, such as aspirin or another medication, to help prevent clots. Talk to your doctor about what is safe for you.
No, you must swallow the capsules whole. Never open, crush, or chew them, as the powder inside is highly toxic and should not contact your skin or be inhaled. Talk to your doctor if you have trouble swallowing capsules.
Your treatment duration depends on how well the medicine works for your condition and how your body tolerates it. Your doctor will monitor your progress regularly. Talk to your doctor to understand your specific treatment plan.
It is best to avoid or limit alcohol while taking Pomacel 3 mg Capsule 21's because it can worsen side effects like dizziness, sleepiness, and nausea. Talk to your doctor about safe limits.
A fever can be a sign of a serious infection due to low white blood cell counts caused by Pomacel 3 mg Capsule 21's. Contact your healthcare team immediately if your temperature rises. Talk to your doctor right away.
No, you must not donate blood while taking Pomacel 3 mg Capsule 21's and for at least 4 weeks after your last dose, as the medicine in your blood could harm an unborn baby if given to a pregnant recipient. Talk to your doctor for more safety guidelines.
Hair loss is not a common side effect of Pomacel 3 mg Capsule 21's, but some patients may experience mild hair thinning. Talk to your doctor if you notice unexpected hair changes during your treatment.
Your doctor will arrange regular blood tests during treatment to check your blood cell counts, kidney function, liver function, and markers of multiple myeloma such as M-protein levels. Depending on your condition, you may also need urine tests, bone marrow tests, or imaging scans to see how well the treatment is working. These tests help your healthcare team decide whether to continue, adjust, or change your therapy.
You should not take Pomacel 3 mg Capsule 21's if you are pregnant, planning pregnancy, or could become pregnant, because it can cause severe birth defects. You should also avoid this medicine if you have ever had a severe allergic reaction to Pomacel 3 mg Capsule 21's, thalidomide, lenalidomide, or any ingredient in the capsule. Tell your doctor about any previous medicine allergies before starting treatment.
The rest period allows your body, especially your bone marrow, time to recover before the next cycle begins. During this time, your doctor will review your blood test results and any side effects to determine when it is safe to restart treatment.

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Country of origin

India

Manufacturer/Marketer address

B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai 400 026.
Other Info - POM0027
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