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  3. Pramirise 0.5 mg Tablet 10's

Pramirise 0.5 mg Tablet 10's, Pack of 10 TABLETS
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Composition :

PRAMIPEXOLE-0.5MG

Manufacturer/Marketer :

Arinna Lifesciences Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pramirise 0.5 mg Tablet

Pramirise 0.5 mg Tablet belongs to a group of antiparkinson agents or dopamine agonists used to treat the symptoms of Parkinson’s disease and moderate to severe Willis-Ekbom disease (restless legs syndrome) in adults. Parkinson’s disease is a progressive neurological disorder in which the first signs are problems with movements. Willis-Ekbom disease is a condition which causes the uncontrollable urge to move the legs.

Pramirise 0.5 mg Tablet contains 'Pramipexole' that works by mimicking the action of dopamine (acting in place of dopamine), a natural substance found in the brain needed to control body movement. This triggers the nerve impulses in the brain that control body movements.

In some cases, you may experience certain common side-effects such as sleepiness, nausea, constipation, dizziness, fatigue, hallucinations, dry mouth, muscle spasms, and peripheral oedema (leg swelling due to fluid overload). Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Do not discontinue Pramirise 0.5 mg Tablet on your own. Consult your doctor if you are pregnant or breastfeeding. Pramirise 0.5 mg Tablet may cause drowsiness and dizziness, do not drive unless you are alert. Pramirise 0.5 mg Tablet should not be used in children below 18 years. Avoid consuming alcohol along with Pramirise 0.5 mg Tablet as it could lead to increased drowsiness and dizziness. Rise slowly from sitting or lying position as Pramirise 0.5 mg Tablet may cause orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). 

Uses of Pramirise 0.5 mg Tablet

Treatment of Parkinson's disease, Willis Ekbom disease (restless legs syndrome).

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Pramirise 0.5 mg Tablet belongs to a group of antiparkinson agents called dopamine agonists used to treat the symptoms of Parkinson’s disease and moderate to severe Willis-Ekbom disease (restless legs syndrome) in adults. Pramirise 0.5 mg Tablet binds to the dopamine receptor and mimics its action. Dopamine is a naturally-occurring neurotransmitter in the brain. Dopamine is absent or reduced in people with Parkinson’s disease. Pramirise 0.5 mg Tablet works by stimulating the dopamine receptors in the brain. This triggers the nerve impulses in the brain that control body movements. Pramirise 0.5 mg Tablet helps in relieving the symptoms of Parkinson’s disease, such as muscle spasms, tremors, stiffness, and poor muscle control.

How Pramirise 0.5 mg Tablet Works

Pramirise 0.5 mg Tablet contains 'Pramipexole' that works by mimicking the action of dopamine (acting in place of dopamine), a natural substance found in the brain needed to control body movement. This triggers the nerve impulses in the brain that control body movements.

Storage

Store in a cool and dry place away from sunlight
Side effects of Pramirise 0.5 mg Tablet
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Uncontrolled and involuntary movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
  • Hallucination is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control hallucinations. You can share what is being seen with a therapist to know whether they are real or imaginary.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your imagination.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of hallucinations.
  • Talk to your dietician and consume food that can improve your mental health.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Do not stand up suddenly. Lie down and get up slowly only when you feel better.
  • Avoid alcohol and large meals.
  • Drink enough water before standing for long periods.
  • Exercise regularly; however, avoid exercising in extreme heat.
  • Eat small, low-carb meals.
  • Wear compression stockings.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Pramirise 0.5 mg Tablet

Do not take more than the prescribed dose of Pramirise 0.5 mg Tablet as it may cause overdose. The symptoms of overdose include fast heart rate. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Pramirise 0.5 mg Tablet if you are allergic to any of its contents. Talk to your doctor before taking Pramirise 0.5 mg Tablet if you have kidney problems, hallucinations, dyskinesia (abnormal limb movements), dystonia (inability to keep the neck straight), sleepiness or suddenly falling asleep, psychosis, vision impairment, severe heart or blood vessel disease, or augmentation (symptoms start earlier). Inform your doctor if you experience symptoms such as apathy, anxiety, depression, fatigue, sweating or pain after dose reduction or stopping Pramirise 0.5 mg Tablet . Pramirise 0.5 mg Tablet may cause intense urges such as increased sex drive, gambling, overeating and wasting money. Consult your doctor if you are pregnant or breastfeeding. Pramirise 0.5 mg Tablet may cause drowsiness and dizziness, do not drive unless you are alert. Pramirise 0.5 mg Tablet should not be given to children below 18 years. Avoid consuming alcohol along with Pramirise 0.5 mg Tablet as it could lead to increased drowsiness and dizziness. Rise slowly from sitting or lying position as Pramirise 0.5 mg Tablet causes orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). 

Drug-Drug Interactions

verifiedApollotooltip
PramipexoleOlanzapine
Critical
PramipexoleRisperidone
Critical

Drug-Drug Interactions

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PramipexoleOlanzapine
Critical
How does the drug interact with Pramirise 0.5 mg Tablet:
Taking Olanzapine with Pramirise 0.5 mg Tablet can increase the risk and severity of side effects and reduce the effectiveness of Pramirise 0.5 mg Tablet.

How to manage the interaction:
Co-administration of Olanzapine and Pramirise 0.5 mg Tablet is not recommended as it leads to an interaction, it can be taken if advised by a doctor. If you experience any symptoms such as drowsiness, dizziness, and lightheadedness, contact a doctor immediately. Avoid driving or operating dangerous machinery, and be careful while getting up from a sitting or lying position. Do not discontinue any medications without consulting a doctor.
PramipexoleRisperidone
Critical
How does the drug interact with Pramirise 0.5 mg Tablet:
Taking Risperidone with Pramirise 0.5 mg Tablet may reduce the effectiveness of Pramirise 0.5 mg Tablet.

How to manage the interaction:
Taking Risperidone with Pramirise 0.5 mg Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, and lightheadedness contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PramipexoleAmisulpride
Severe
How does the drug interact with Pramirise 0.5 mg Tablet:
Taking Amisulpride with Pramirise 0.5 mg Tablet may decrease the efficacy of both medications.

How to manage the interaction:
Although taking amisulpride along with Pramirise 0.5 mg Tablet can result in an interaction, it can be taken if a doctor has advised it. Avoid jobs that demand mental awareness and exercise caution while rising from a sitting or sleeping posture. Do not discontinue any medications without a doctor's advice.
PramipexoleEsketamine
Severe
How does the drug interact with Pramirise 0.5 mg Tablet:
Combining Esketamine with Pramirise 0.5 mg Tablet may increase side effects

How to manage the interaction:
Although taking Pramirise 0.5 mg Tablet and Esketamine together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience any symptoms like drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination, consult a doctor. Do not discontinue the medication without consulting a doctor.
PramipexoleSodium oxybate
Severe
How does the drug interact with Pramirise 0.5 mg Tablet:
Taking Sodium oxybate with Pramirise 0.5 mg Tablet may increase he risk of side effects.

How to manage the interaction:
Taking Pramirise 0.5 mg Tablet with Sodium oxybate together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, lightheadedness, confusion, depression, low blood pressure, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination, consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.

  • Include a diet rich in iron, folate and magnesium. 

  • Regularly attend therapy sessions.

  • Perform meditation and yoga.

  • Follow a regular sleep pattern.

  • Avoid smoking and alcohol consumption.

  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

ANTIPARKINSON AGENTS

Pramirise 0.5 mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Pramirise 0.5 mg Tablet as it may cause increased dizziness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Do not take Pramirise 0.5 mg Tablet if you are breastfeeding. Pramirise 0.5 mg Tablet may reduce the production of breast milk. Also, it can pass into breast milk. If taking Pramirise 0.5 mg Tablet is unavoidable, stop breastfeeding.

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Driving

Unsafe

Pramirise 0.5 mg Tablet may cause dizziness, sleepiness and hallucinations. Avoid driving and handling machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Pramirise 0.5 mg Tablet is not recommended for use in children below 18years.

Have a query?

FAQs

Pramirise 0.5 mg Tablet is used to treat Parkinson's disease and Willis Ekbom disease (restless legs syndrome).

Pramirise 0.5 mg Tablet works by acting like dopamine and triggering the nerve impulses in the brain that controls our body movements like restless leg syndrome and Parkinson's.

Pramirise 0.5 mg Tablet may lower the blood pressure than normal leading to hypotension (low blood pressure), especially during the initial days of treatment. Do not stand up suddenly, rise slowly to avoid a sudden drop in blood pressure. Regularly monitor your blood pressure levels while taking Pramirise 0.5 mg Tablet .

Dry mouth could be a side-effect of Pramirise 0.5 mg Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Pramirise 0.5 mg Tablet may cause peripheral oedema (swelling of lower legs and hands due to fluid overload). So, avoid sitting or standing for too long.

Hallucination is a medical condition in which the person may feel, hear or believe things that are not true, see things that are not there, feel unusually suspicious or confused. If you experience hallucinations, please talk to your doctor immediately.

Do not discontinue Pramirise 0.5 mg Tablet without consulting your doctor, as it could lead to recurring symptoms. To treat your condition effectually, continue taking Pramirise 0.5 mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Pramirise 0.5 mg Tablet .

Pramirise 0.5 mg Tablet may be indicated in the treatment of restless leg syndrome. It should be taken 2-3 hours before bedtime or as advised by the doctor.

Country of origin

India

Manufacturer/Marketer address

3M India Ltd, Concorde Block, Ub City, #24, Vittal Mallya Road, Bangalore, Karnataka - 560001 India
Other Info - PRA0262

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:49 PM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/022421s003lbl.pdfhttp://mri.cts-mrp.eu/download/AT_H_0314_005_FinalPL.pdf
  2. https://www.ema.europa.eu/en/documents/product-information/pramipexole-accord-epar-product-information_en.pdf
  3. https://www.drugs.com/mtm/pramipexole.html

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