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compositionComposition:LOTEPREDNOL ETABONATE-0.5%W/V
prescription
Prescription Medicine
info
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Predflam 0.5% Eye Drop is an ophthalmic medicine used in the treatment of post-operative inflammation and pain following ocular surgery. This medicine belongs to the class of corticosteroids, which work by blocking prostaglandins (a chemical messenger) in the brain that cause inflammation and swelling. Common side effects include watery eyes, irritation, itching, and a foreign body sensation in the eye. It is advised not to touch the tip of the container with your fingers, as it can lead to contamination of the medication.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

LOTEPREDNOL ETABONATE-0.5%W/V

Consume Type :

Ophthalmic

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Predflam 0.5% Eye Drop

Predflam 0.5% Eye Drop is a prescription corticosteroid eye drop used to treat eye inflammation, swelling, and redness caused by allergies, infections, or surgery. It works directly in the eye to calm down the body's natural defence response, providing rapid relief from discomfort. Doctors typically prescribe it for the short-term relief of various inflammatory eye conditions.

To get the best results, you must use Predflam 0.5% Eye Drop consistently and exactly as prescribed by your doctor. Because these are eye drops, you do not need to take them with food, but you should always wash your hands before each application. Making simple changes, such as wearing sunglasses outdoors and avoiding dusty environments, can also support your eye's healing process.

While using Predflam 0.5% Eye Drop, you might experience mild side effects like temporary burning, stinging, or watery eyes. However, if you notice severe eye pain, changes in your vision, or signs of a new eye infection, you must contact your doctor immediately. Regular eye exams are often necessary to check your eye pressure if you use these drops for more than a few days.

Before starting this medication, tell your doctor if you have glaucoma, cataracts, or a history of high pressure inside your eyes. Do not take this if you have an active viral, fungal, or mycobacterial eye infection, as steroids can make these infections worse. This product should also be avoided by anyone with a known allergy to any of its ingredients.

Using Predflam 0.5% Eye Drop alongside other eye drops or certain oral medications can sometimes lead to drug interactions, so always share your full medication list with your doctor. If you are pregnant, planning to become pregnant, breastfeeding, or caring for an elderly patient, consult your healthcare provider to discuss the safety of this treatment. Additionally, avoid smoking and drinking alcohol, as they can dry out your eyes and slow down your natural recovery.
 

Uses of Predflam 0.5% Eye Drop

Your doctor may prescribe Predflam 0.5% Eye Drop to help manage the following conditions:

  • Post-operative eye inflammation: Predflam 0.5% Eye Drop helps reduce swelling, pain, and redness after eye surgeries, such as cataract surgery, ensuring a smoother and faster healing process.
  • Allergic conjunctivitis: Predflam 0.5% Eye Drop provides relief from severe eye itching, redness, and swelling caused by environmental allergens like pollen, dust, or pet dander.
  • Uveitis and anterior segment inflammation: Predflam 0.5% Eye Drop reduces deep-seated inflammation in the front part of the eye, protecting sensitive ocular tissues from long-term damage.
  • Dry eye disease flare-ups: Predflam 0.5% Eye Drop temporarily calms severe inflammation on the surface of the eye, helping to relieve intense dryness, burning, and grittiness.
     

Key Benefits

Predflam 0.5% Eye Drop is a corticosteroid used to reduce inflammation and relieve symptoms associated with various eye conditions. It helps control redness, swelling, pain, and irritation, promoting comfort and supporting recovery.

  • Reduces Eye Inflammation: Helps relieve inflammation, redness, and swelling caused by eye conditions, surgery, or injury.
  • Relieves Eye Discomfort: Helps reduce symptoms such as pain, irritation, burning, and sensitivity associated with eye inflammation.
  • Supports Healing: By controlling inflammation, it promotes healing and helps protect eye tissues from inflammation-related damage.
  • Acts Directly on the Eye: Applied locally to the affected eye, it provides targeted treatment with minimal systemic absorption.
  • Improves Daily Comfort: By reducing inflammation and irritation, it helps make activities such as reading, driving, and using digital screens more comfortable.
     

Directions for Use

  • Predflam 0.5% Eye Drop is typically used 1-2 times a day, or as prescribed by your healthcare provider, based on the severity of the condition.
  • Tilt your head back, gently pull down your lower eyelid to create a small pocket, and drop the prescribed number of drops into the affected eye. Close your eye and gently press the corner of your eye near the nose for 1-2 minutes to prevent the drops from draining out.
  • Avoid touching the dropper to any surface, including your eyes, to prevent contamination.
  • Before using eye drops, wash your hands thoroughly.
  • It is for ophthalmic use only.

How Predflam 0.5% Eye Drop Works

Predflam 0.5% Eye Drop contains loteprednol etabonate. It belongs to a group of medicines known as corticosteroids. When you apply the drops to your eye, the active medicine passes into the ocular tissues and stops the production of certain natural chemicals called prostaglandins and leukotrienes. These chemicals are the primary triggers for swelling, redness, itching, and pain. By blocking these inflammatory signals at their source, Predflam 0.5% Eye Drop calms the local immune response. This targeted action allows the delicate structures of your eye to heal from surgery, allergies, or injury without experiencing prolonged, damaging inflammation.
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Alcohol

Consult your doctor

It is unknown if alcohol affects Predflam 0.5% Eye Drop. Please consult your doctor for more information.

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Pregnancy

Consult your doctor

Please consult your doctor, as there are no adequate and well-controlled studies in pregnant women. Your doctor will prescribe only if the benefit outweighs the risks.

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Breast Feeding

Consult your doctor

Please consult your doctor before using Predflam 0.5% Eye Drop if you are a nursing mother.

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Driving

Unsafe

Predflam 0.5% Eye Drop can cause temporary blurry vision. So, do not drive or operate machinery until your vision is clear.

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Liver

Consult your doctor

Please consult your doctor if you have any concerns regarding the usage of Predflam 0.5% Eye Drop in patients with liver problems.

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Kidney

Consult your doctor

Please consult your doctor if you have any concerns about using Predflam 0.5% Eye Drop in patients with kidney problems.

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Children

Unsafe

Safety and effectiveness in pediatric patients have not been established. Please consult your doctor for more information.

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Heart

Safe if prescribed

Predflam 0.5% Eye Drop is generally considered safe for individuals with heart conditions. However, please consult your doctor if you have any concerns.

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Geriatrics

Safe if prescribed

Predflam 0.5% Eye Drop is generally considered safe for elderly patients when used as prescribed by a doctor. Please consult your doctor before using Predflam 0.5% Eye Drop.

What if I have taken an overdose of Predflam 0.5% Eye Drop

An overdose of ophthalmic drops is highly unlikely to cause serious harm. However, if you accidentally put too many drops in your eye, rinse it thoroughly with clean, lukewarm water. If someone accidentally swallows the liquid, seek immediate medical attention or contact a poison control centre.

Diet & Lifestyle Advise

  • Wear sunglasses: Protect your healing or inflamed eyes from bright sunlight and wind by wearing UV-protective sunglasses outdoors.
  • Avoid rubbing your eyes: Rubbing can worsen inflammation, damage delicate eye tissues, or introduce harmful bacteria.
  • Practice good eyelid hygiene: Gently clean your eyelids with a warm, damp cloth if you have crusting, ensuring your hands are washed first.
  • Limit screen time: Give your eyes regular breaks from computers, phones, and televisions to prevent dryness and eye strain.
    Stay hydrated: Drink plenty of water throughout the day to support natural tear production and eye moisture.
     
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Have a query?

What if you forget to take Predflam 0.5% Eye Drop

If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and return to your regular schedule. Do not apply a double dose to make up for the missed one.

Storage

•Store Predflam 0.5% Eye Drop at room temperature, ideally between 15°C and 25°C (59°F and 77°F).

Drug Warnings

  • Shake the Bottle Well: If using the suspension, shake the bottle thoroughly before each use to ensure the medicine is evenly mixed.
  • Avoid Contaminating the Dropper: Do not let the dropper tip touch your eye, fingers, or any other surface to help prevent contamination and eye infections.
  • Remove Contact Lenses Before Use: Take out contact lenses before applying the eye drops and wait at least 15 minutes before reinserting them, unless your doctor advises otherwise.
  • Inspect the Solution Before Use: Do not use the eye drops if the solution appears cloudy, discoloured, contains particles, or if the bottle is damaged.
  • Space Multiple Eye Medicines: If you use more than one eye medication, wait at least 5–10 minutes between applications to prevent one medicine from washing out the other.
  • Avoid Driving Until Vision Clears: Your vision may be temporarily blurred after applying the drops. Do not drive or operate machinery until you can see clearly.
     

verifiedApollotooltip

Predflam 0.5% Eye Drop may interact with certain medicines, affecting its effectiveness or increasing the risk of side effects.

  • Other corticosteroid eye drops: Using other steroid eye drops alongside Predflam 0.5% Eye Drop may increase the risk of high pressure in the eye or cataracts.
  • Glaucoma medications: Predflam 0.5% Eye Drop may decrease the effectiveness of eye drops used to lower pressure in the eyes, requiring close monitoring.
     

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verifiedApollotooltip

No clinically significant food interactions are known with Predflam 0.5% Eye Drop when used as directed.
 

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CORTICOSTEROIDS]

FAQs

Predflam 0.5% Eye Drop is used to treat post-operative inflammation and pain following ocular surgery.
Predflam 0.5% Eye Drop works by blocking prostaglandins (a chemical messenger) in the brain, which causes inflammation and swelling. As a result, Predflam 0.5% Eye Drop reduces inflammation and pain.
Predflam 0.5% Eye Drop should be taken in the dose and duration as advised by the doctor. If you take more than the recommended dose, it may cause unwanted side effects, such as increased eye pressure, fungal infection, optic nerve damage, vision problems, or cataracts. If you think your symptoms are not improving, please consult your doctor.
Do not stop taking Predflam 0.5% Eye Drop without talking to your doctor. Continue using Predflam 0.5% Eye Drop for as long as it has been advised by the doctor to treat your condition effectively. If you experience any difficulty while using Predflam 0.5% Eye Drop, consult your doctor.
Avoid wearing contact lenses while using Predflam 0.5% Eye Drop. If you are wearing contact lenses, remove them and wait 15 minutes after applying the drops. However, wearing contact lenses is not recommended post-cataract surgery. Your doctor may advise you to wear glasses as they help the eyes recover from the operative procedure.
Predflam 0.5% Eye Drop should be used with other eye medications only if prescribed by the doctor. If you are using any other eye medications, inform your doctor as anti-glaucoma agents may increase the effects of Predflam 0.5% Eye Drop.
The common side effects of Predflam 0.5% Eye Drop include watery eyes, irritation, itching, and a foreign body sensation in the eye. Most of these side effects are temporary; however, if they persist, please consult your doctor.
Before using Predflam 0.5% Eye Drop, make sure you are not allergic to any of its components or corticosteroids. Inform your doctor if you have or ever had glaucoma (increased eye pressure), herpes simplex infection, or any other eye problem. Also, let your doctor know if you are pregnant and breastfeeding, wearing contact lenses, or taking other medications. Always follow the prescribed dosage and avoid contact with the dropper tip to prevent contamination.
Predflam 0.5% Eye Drop should only be used during pregnancy if prescribed by your doctor. Since information on its safety during pregnancy may be limited, your doctor will prescribe it only if the benefits outweigh the risks.
Yes, Predflam 0.5% Eye Drop is effective when used at the dose and duration recommended by your doctor. If you stop using Predflam 0.5% Eye Drop too early, the symptoms may return or worsen.
The use of Predflam 0.5% Eye Drop should be avoided in individuals who are allergic to any of its components. It is also not recommended for use in most viral infections of the cornea and conjunctiva, such as herpes simplex infection, as well as in mycobacterial and fungal infections of the eye. If you have any concerns about using Predflam 0.5% Eye Drop, please consult your doctor.
Predflam 0.5% Eye Drop should be stored at room temperature, away from direct sunlight. Keep it out of reach of children.
No, you should not wear contact lenses while applying Predflam 0.5% Eye Drop. The preservative in the drops can be absorbed by soft contact lenses and cause discolouration or irritation. Remove your lenses before using the drops and wait at least 15 minutes before putting them back in. Talk to your doctor for specific advice.
No, Predflam 0.5% Eye Drop is a steroid that reduces inflammation, redness, and swelling, but it does not cure infections caused by bacteria, viruses, or fungi. In fact, using it alone during an active infection can make the infection worse. If you suspect an infection, talk to your doctor.
It is very common to experience mild, temporary blurriness immediately after applying the drops. This usually clears up within a few minutes. Avoid driving or operating machinery until your vision is completely clear. If the blurriness persists, talk to your doctor.
Long-term use of Predflam 0.5% Eye Drop should only occur under the close supervision of an eye specialist. Using steroid eye drops for an extended period can increase the pressure inside your eyes or lead to cataracts. If you need long-term treatment, talk to your doctor.
Yes, but you must space them out properly. Wait at least 5 to 10 minutes between using Predflam 0.5% Eye Drop and any other eye drops to prevent the second drop from washing out the first. Talk to your doctor or pharmacist to set up a safe schedule.
Yes, like all corticosteroid eye drops, Predflam 0.5% Eye Drop can cause an increase in the pressure inside your eyes, especially with prolonged use. Your doctor will likely monitor your eye pressure if you need to use this medication for more than a couple of weeks. Talk to your doctor.
Generally, you should discard any remaining eye drops 4 weeks after first opening the bottle, as bacteria can enter and contaminate the liquid over time. Always check the packaging for specific instructions, and if you are unsure, talk to your doctor or pharmacist.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. MedlinePlus. A619025 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Loteprednol Ophthalmic Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. U.S. Food and Drug Administration (FDA). 202872Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  4. Loteprednol Loteprednol. 2004. [Accessed on 04 Apr. 2019]Check here
  5. Venkateswaran N, Bian Y, Gupta PK Practical Guidance for the Use of Loteprednol Etabonate Ophthalmic Suspension 0.25% in the Management of Dry Eye Disease. Clin Ophthalmol. 2022;16:349-355Check here
  6. Ema. loteprednol etabonate. [[Accessed on 9.sept].2019]Check here
  7. Dailymed. loteprednol etabonate. [[Accessed on 9.sept].2019]Check here

Country of origin

India
Other Info - PR77873
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