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compositionComposition:PREDNISOLONE-5MG
prescription
Prescription Medicine
info
Prednisolone 5 mg Tablet 10's

Prednisolone 5 mg Tablet is used to treat various medical conditions such as allergies, joint inflammation (arthritis), breathing problems (e.g., asthma), certain blood disorders, collagen diseases (e.g., lupus), certain eye diseases (e.g., keratitis), cancer (e.g., leukaemia), endocrine problems (e.g., adrenocortical insufficiency), intestinal problems (e.g., ulcerative colitis), swelling due to certain conditions, or skin conditions (e.g., psoriasis). It prevents the release of substances that cause inflammation (redness and swelling) and allergies. Besides this, it is also prescribed to prevent organ rejection after a transplant. It contains Prednisolone, which decreases inflammation and suppresses the immune system. In some cases, you may experience side effects such as weight gain, indigestion, problems sleeping (insomnia), restlessness, mild mood changes and sweating.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PREDNISOLONE-5MG

Manufacturer/Marketer :

Wockhardt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Prednisolone 5 mg Tablet

Prednisolone 5 mg Tablet is a prescription steroid medicine used to treat a wide variety of inflammatory and allergic conditions. It works by reducing swelling, redness, and irritation throughout the body, helping to manage conditions like severe asthma, arthritis, and skin disorders. Your doctor may also prescribe it to treat certain immune system disorders where the body attacks its own tissues.

It is very important to take Prednisolone 5 mg Tablet consistently and exactly at the times your doctor recommends to keep your symptoms under control. You should always take this medicine with food or a glass of milk to prevent stomach upset. Making simple lifestyle adjustments, such as reducing your salt intake, can also help manage fluid retention while using this medication.

While taking this medicine, some people may experience common side effects such as an increased appetite, trouble sleeping, or mild mood changes. However, you must contact your doctor immediately if you notice serious symptoms like severe stomach pain, signs of an infection, or unusual changes in your vision.

Do not take this medicine if you have an active, untreated fungal infection anywhere in your body. Before starting treatment, talk to your doctor if you have a history of diabetes, high blood pressure, stomach ulcers, or bone thinning, as this medication can make these conditions worse.

This medicine can interact with other drugs, including common pain relievers, and drinking alcohol while taking it can increase your risk of stomach bleeding. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, consult your doctor for personalised advice before starting treatment.

Uses of Prednisolone 5 mg Tablet

Prednisolone 5 mg Tablet is used to treat a wide range of inflammatory, allergic, and immune-related conditions. The detailed uses of Prednisolone 5 mg Tablet are as follows: 

  • Severe allergic reactions: Helps calm the body's overactive immune response to relieve swelling, hives, and severe itching.
  • Asthma and breathing disorders: Reduces swelling and irritation in the airways, making it easier to breathe during severe flare-ups.
  • Arthritis and joint inflammation: Eases painful joint swelling, stiffness, and heat, allowing for better physical movement.
  • Inflammatory bowel diseases: Controls inflammation in the digestive tract to manage symptoms like stomach pain and severe diarrhoea.
  • Skin conditions: Treats severe dermatological issues like eczema and psoriasis by reducing redness, scaling, and itching.

Key Benefits

Prednisolone 5 mg Tablet helps reduce inflammation and suppress an overactive immune response, providing relief from symptoms associated with a wide range of inflammatory and autoimmune conditions. Its benefits include:

  • Reduces Inflammation Quickly: Acts rapidly to control inflammation, helping relieve swelling, redness, and pain associated with inflammatory conditions.
  • Relieves Pain and Discomfort: By reducing inflammation, it may help improve comfort and make daily activities easier to perform.
  • Controls Symptom Flare-Ups: Helps manage sudden flare-ups of chronic inflammatory or autoimmune conditions, reducing symptom severity and improving disease control.
  • Protects Against Long-Term Damage: By controlling ongoing inflammation, it may help reduce the risk of long-term damage to the joints, lungs, skin, and other organs.
  • Improves Physical Function: Helps restore mobility and support smoother, more comfortable movement by reducing inflammation-related stiffness and pain.
Side effects of Prednisolone 5 mg Tablet
  • Avoid diet rich in salt and carbohydrates
  • Drink plenty of water and stay hydrated.
  • Exercise regularly and maintain a healthy lifestyle.
  • Take potassium rich foods like potatoes, spinach, tomatoes, sea food and dairy products.
  • Take beverages containing caffeine like coffee and tea.
  • Consult your doctor if you experience severe symptoms like high blood sugar, increased thirst, urination, or blurred vision to check if your medication is the cause.
  • Your doctor may adjust your medications to reduce the risk of impaired blood sugar regulation.
  • Eat a balanced diet rich in whole foods like fruits, vegetables, whole grains, and lean proteins.
  • Protein and healthy fats, such as avocado, almonds, and seeds, can help manage blood sugar levels.
  • Limit added sugars from sugary drinks, baked goods, and candy.
  • To maintain your blood sugar levels within a healthy range, check them frequently.
  • Eat a balanced diet containing enough proteins, fibre, healthy fats, vegetables and fruits.
  • Get quality sleep for about 7-9 hours.
  • Try to manage stress with meditation or yoga.
  • Drink enough water.
  • Exercise regularly as it helps regulate appetite.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.

Directions for Use

Take this medicine exactly as prescribed by your doctor. Do not change your dose or stop taking it without medical advice.

  • Swallow the tablet whole with a full glass of water. If you are taking the liquid form, measure the dose carefully using a medical dosing spoon or syringe, not a regular kitchen spoon.
  • Always take your dose with food or a glass of milk to protect your stomach lining from irritation.
  • Try to take your dose at the same time every morning. This matches your body's natural hormone cycle and helps prevent sleep disturbances.

If your doctor decides to stop the treatment, they will provide instructions for gradually decreasing the dose. Stopping this medicine suddenly can cause serious fatigue, dizziness, and stomach upset.

How Prednisolone 5 mg Tablet Works

Prednisolone 5 mg Tablet contains prednisolone, a corticosteroid, which means it acts like the natural hormones produced by your body's adrenal glands. During an allergic reaction or inflammatory flare-up, your immune system releases chemicals that trigger pain and swelling. Prednisolone 5 mg Tablet works by blocking the production of these inflammatory chemicals, effectively calming down the overactive immune response to protect your tissues from irritation.
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Alcohol

Caution

You are recommended not to consume alcohol along with Prednisolone 5 mg Tablet to avoid unpleasant side effects like excessive dizziness.

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Pregnancy

Caution

Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. Prednisolone 5 mg Tablet isn't usually recommended in pregnancy unless the potential benefits outweigh the risks.

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Breast Feeding

Caution

Prednisolone 5 mg Tablet should be used during breastfeeding only after a careful assessment of the benefit-risk ratio to the mother and infant. You should not take Prednisolone 5 mg Tablet without a doctor's advice.

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Driving

Caution

Prednisolone 5 mg Tablet usually causes dizziness, drowsiness and visual disturbances, which may affect their ability to drive or operate machinery. Make sure you are not affected before driving or operating machinery.

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Liver

Caution

Prednisolone 5 mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Prednisolone 5 mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Generally, Prednisolone 5 mg Tablet is not recommended for children as it affects growth; take it only if prescribed. In case it has to be given, then the dose has to be adjusted and recommended by a child specialist only.

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Heart

Caution

Prednisolone 5 mg Tablet can be used in patients with heart conditions with caution. It's crucial to consult your doctor to determine if the benefits outweigh the risks in your specific case.

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Geriatrics

Caution

Geriatric patients can take Prednisolone 5 mg Tablet if prescribed by the physician. It's important to use it under close medical supervision with tailored dosing and regular monitoring.

What if I have taken an overdose of Prednisolone 5 mg Tablet

Prednisolone 5 mg Tablet overdose is unlikely to produce life-threatening symptoms. However, long term use of high steroid doses can lead to symptoms such as easy bruising, thinning skin, changes in the shape or location of body fat (especially in your neck, face, back, and waist), menstrual problems, increased facial hair or acne, impotence, or loss of interest in sex.

Diet & Lifestyle Advise

  • Limit your salt intake: Avoid highly processed and salty foods to help prevent fluid retention and swelling in your ankles and feet.
  • Eat calcium-rich foods: Include dairy products, leafy greens, or calcium supplements in your diet to help protect your bones from thinning during treatment.
  • Monitor blood sugar: If you have diabetes, check your blood sugar levels more frequently, as this medicine can cause blood sugar to rise.
  • Stay away from sick individuals: This medication can temporarily lower your body's ability to fight off infections, so wash your hands frequently and avoid close contact with people who have contagious illnesses.

Have a query?

How Soon It Starts Working

The time required for Prednisolone 5 mg Tablet to start to work: The time required for Prednisolone 5 mg Tablet to start to work is 1 hour after administration. The time for which the effects of Prednisolone 5 mg Tablet last: The effect of Prednisolone 5 mg Tablet lasts for 8 to 9 hours.

What if you forget to take Prednisolone 5 mg Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

•Store Prednisolone 5 mg Tablet tablets or liquid at room temperature, between 15°C and 30°C (59°F to 86°F). •Keep the bottle tightly closed and store it in a dry place away from direct light and moisture; do not store it in the bathroom.

Drug Warnings

  • Inspect Before Use: Always inspect the liquid form before taking it. Do not use the solution if it contains floating particles or has changed colour.
  • Avoid Live Vaccines: Do not receive live vaccines, such as yellow fever or measles vaccines, without consulting your doctor, as they may be less effective or increase the risk of infection while taking Prednisolone 5 mg Tablet .
  • Carry Medical Identification: Carry a medical alert card or wear a medical identification bracelet stating that you are taking an oral steroid medicine.
  • Inform Healthcare Providers: Tell any doctor, surgeon, or dentist treating you that you are taking Prednisolone 5 mg Tablet , especially before surgery or emergency medical treatment.
  • Monitor Wound Healing: Watch for cuts, sores, or wounds that heal slowly and report any delayed healing to your doctor.

Drug-Drug Interactions

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with Prednisolone 5 mg Tablet : 

  • Pain relievers (NSAIDs like ibuprofen or aspirin): Taking these with Prednisolone 5 mg Tablet can significantly increase your risk of stomach ulcers and bleeding.
  • Blood thinners (like warfarin): This medicine can alter how blood thinners work, requiring closer monitoring of your blood clotting times.
  • Diabetes medicines: Prednisolone 5 mg Tablet may raise your blood sugar, which can decrease the effectiveness of your diabetes medications.

Drug-Food Interactions

Certain foods and beverages may affect how Prednisolone 5 mg Tablet works or increase the risk of side effects. Examples include: 

  • Grapefruit juice: Drinking grapefruit juice can increase the level of this medicine in your blood, raising the risk of side effects.
  • Alcohol: Consuming alcohol while on this medication increases the risk of stomach irritation and ulcers.

Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking Prednisolone 5 mg Tablet , as it may worsen your condition or require additional monitoring: 

  • Active infections: This medicine can weaken your immune response, which may hide the signs of an active infection or make it worse.
  • Diabetes: May cause high blood sugar levels, making it harder to manage your diabetes.
  • Osteoporosis: Long-term use can accelerate bone thinning, potentially worsening osteoporosis.
PrednisoloneDesmopressin
Critical
PrednisoloneBCG vaccine
Critical

Drug-Drug Interactions

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PrednisoloneDesmopressin
Critical
How does the drug interact with Prednisolone 5 mg Tablet 5 mg Tablet:
Co-administration of Prednisolone 5 mg Tablet and Desmopressin may increase the risk of hyponatremia (low levels of sodium in the blood).

How to manage the interaction:
Taking Prednisolone 5 mg Tablet with Desmopressin is not generally advised as they lead to an interaction, they can be taken together if advised by a doctor. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
PrednisoloneBCG vaccine
Critical
How does the drug interact with Prednisolone 5 mg Tablet 5 mg Tablet:
When BCG vaccine is used with Prednisolone 5 mg Tablet, its effectiveness may be reduced.

How to manage the interaction:
Taking Prednisolone 5 mg Tablet with BCG vaccine is not generally advised, but they can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
PrednisoloneMifepristone
Critical
How does the drug interact with Prednisolone 5 mg Tablet 5 mg Tablet:
When Mifepristone is taken with Prednisolone 5 mg Tablet, the effects of Prednisolone 5 mg Tablet might be considerably reduced, which may be less effective in treating your condition.

How to manage the interaction:
Taking Prednisolone 5 mg Tablet with Mifepristone is not recommended, they can be taken together if advised by a doctor. Do not discontinue the medication without consulting a doctor.
PrednisoloneIohexol
Critical
How does the drug interact with Prednisolone 5 mg Tablet 5 mg Tablet:
Co-administration of Iohexol and Prednisolone 5 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Prednisolone 5 mg Tablet with Iohexol is not generally advised as they can lead to an interaction, they can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
PrednisoloneMoxifloxacin
Severe
How does the drug interact with Prednisolone 5 mg Tablet 5 mg Tablet:
Co-administration of Moxifloxacin may cause tendinitis (inflammation of a tissue that attaches muscle to bone) and tendon rupture (injuries to the soft tissues that connect muscles and joints).

How to manage the interaction:
Although there is an interaction, Prednisolone 5 mg Tablet can be taken with Moxifloxacin if prescribed by the doctor. However, if you experience pain, inflammation, or swelling of a tendon area (back of the ankle, biceps, shoulder, hand, or thumb), consult a doctor. Do not stop using any medications without a doctor's advice.
PrednisoloneVoclosporin
Severe
How does the drug interact with Prednisolone 5 mg Tablet 5 mg Tablet:
Co-administration of Prednisolone 5 mg Tablet and Voclosporin use together may increase the risk of serious infections and some cancers, such as skin cancer and cancer of the lymph nodes (lymphoma).

How to manage the interaction:
Although taking Prednisolone 5 mg Tablet and Voclosporin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, shortness of breath, blood in the coughing fluid, weight loss, red or irritated skin, body sores, or discomfort or burning while urinating, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
PrednisoloneBupropion
Severe
How does the drug interact with Prednisolone 5 mg Tablet 5 mg Tablet:
Bupropion is capable of causing seizures (fits) and combining it with Prednisolone 5 mg Tablet, may enhance the risk.

How to manage the interaction:
Although taking Prednisolone 5 mg Tablet and Bupropion together can result in an interaction, it can be taken if a doctor has prescribed it. You should avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
PrednisoloneDesirudin
Severe
How does the drug interact with Prednisolone 5 mg Tablet 5 mg Tablet:
Taking Prednisolone 5 mg Tablet and Desirudin together can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
There may be a possibility of interaction between Prednisolone 5 mg Tablet and Desirudin, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
PrednisoloneIbuprofen
Severe
How does the drug interact with Prednisolone 5 mg Tablet 5 mg Tablet:
Co-administration of Prednisolone 5 mg Tablet and Ibuprofen can increase the risk of side effects of each other.

How to manage the interaction:
A combination of Prednisolone 5 mg Tablet and Ibuprofen can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
PrednisoloneGrepafloxacin
Severe
How does the drug interact with Prednisolone 5 mg Tablet 5 mg Tablet:
Co-administration of Grepafloxacin may cause tendinitis (inflammation of a tissue that attaches muscle to bone) and tendon rupture, and the risk may be increased when combined with Prednisolone 5 mg Tablet.

How to manage the interaction:
Although there is an interaction, Prednisolone 5 mg Tablet can be taken with Grepafloxacin if prescribed by the doctor. However, if you experience pain, inflammation, or swelling of a tendon area such as the back of the ankle, biceps, shoulder, hand, or thumb, stop taking grepafloxacin and consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Prednisolone 5 mg Tablet is used to treat various medical conditions such as allergies, joint inflammation (arthritis), breathing problems (e.g., asthma), certain blood disorders, collagen diseases (e.g., lupus), certain eye diseases (e.g., keratitis), cancer (e.g., leukaemia), endocrine problems (e.g., adrenocortical insufficiency), intestinal problems (e.g., ulcerative colitis), swelling due to certain conditions, or skin conditions (e.g., psoriasis).
Depending upon the severity of your medical condition, your doctor may prescribe it to you daily for a specific duration. However, do not take it endlessly on your own without a doctor's advice.
Your symptoms may improve before the problem is completely cured. But, completing the full course of treatment would be suggested even if you feel better.
While taking Prednisolone 5 mg Tablet , do not receive a vaccine (including measles, mumps, polio, chickenpox) as the vaccine may not work, and you may develop the disease again.
Yes, Prednisolone 5 mg Tablet is known to cause an upset stomach. So, please take Prednisolone 5 mg Tablet with a meal to avoid an upset stomach.
No, it is a prescribed drug given by a physician to prevent specific medical conditions. Taking it on your own can cause unwanted side effects.
No, you should never stop taking this medicine suddenly. Stopping it abruptly can cause your body to experience severe withdrawal symptoms like extreme fatigue and dizziness. Talk to your doctor, who will show you how to gradually decrease your dose safely.
Taking this medicine in the morning aligns with your body's natural daily cycle of steroid hormones. It also helps prevent sleep problems, which can occur if you take the medication late in the evening. Talk to your doctor if you need help scheduling your doses.
Yes, this medicine can increase your appetite and cause your body to hold onto extra fluid, which may lead to weight gain. Managing your portion sizes and limiting salt in your diet can help control this. Talk to your doctor if you are concerned about weight changes.
You should avoid taking pain relievers like ibuprofen or naproxen while taking this medicine, as the combination can harm your stomach lining. Paracetamol is generally safer, but you should always talk to your doctor or pharmacist before taking any new medication.
Yes, this medicine can cause your blood sugar levels to rise. If you have diabetes or prediabetes, you will need to monitor your blood sugar closely and contact your doctor if you notice consistently high readings. Talk to your doctor about adjusting your diabetes treatment if necessary.
It depends on the type of vaccine. You should avoid live vaccines while taking this medication because your immune system may be too weak to respond safely. Always talk to your doctor before scheduling any vaccination.
This medicine is only used during pregnancy if the benefits outweigh the potential risks to the baby. Your doctor will carefully evaluate your situation and prescribe the lowest effective dose if it is necessary. Talk to your doctor if you are pregnant or planning to become pregnant.
Because this medicine can lower your body's ability to fight off infections, a fever could be a sign of a serious issue. You should contact your doctor right away for advice if you develop a fever, chills, or a sore throat.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. National Health Service (NHS). Prednisolone - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026] Check here
  2. Electronic Medicines Compendium (EMC). Pil.7239 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  3. Drugs.com Clinical Review Team. Prednisolone Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  4. Electronic Medicines Compendium (EMC). Pil.5887 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  5. Prednisolone 1mg Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 2 December 2021] Check here
  6. Prednisolone 1mg Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 2 December 2021] Check here
  7. Prednisolone [Internet]. Ncbi.nlm.nih.gov. 2021 [Accessed on 2 December 2021]Check here

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802 / 1901, Plot No. C-70, G-Block,Bandra Kurla Complex, Bandra (East),Mumbai,Maharashtra,INDIA,400051.
Other Info - PRE0090

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