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  3. Preflunase 0.055% Nasal Spray 12 ml

Preflunase 0.055% Nasal Spray 12 ml, Pack of 1 NASAL SPRAY
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Preflunase 0.055% Nasal Spray is used to treat symptoms of allergic rhinitis. It contains Fluticasone furoate which works by blocking certain chemical messengers that cause allergy. In some cases, this medicine may cause side effects such as nasal ulceration, headache, shortness of breath, soreness, or dryness inside the nose. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

FLUTICASONE FUROATE-0.055%W/W

Manufacturer/Marketer :

Precept Pharma

Consume Type :

NASAL

Return Policy :

Not Returnable

Expires on or after :

About Preflunase 0.055% Nasal Spray

Preflunase 0.055% Nasal Spray is used to treat allergic rhinitis symptoms (inflammation of the nose's inner mucous membrane), such as sneezing, runny nose, and sinus discomfort in adults and children above six years. An allergy is an immune system response to foreign elements typically not harmful to your body. These foreign elements are known as ‘allergens.’

Preflunase 0.055% Nasal Spray is a glucocorticoid that helps treat nasal allergy symptoms. It works by blocking certain chemical messengers present in the brain, causing pain, inflammation (swelling), and allergies. As a result, the Preflunase 0.055% Nasal Spray provides relief from the discomfort and irritation in the nose caused due to allergies. Preflunase 0.055% Nasal Spray may lower your ability to fight infections, so stay away from people who have any infectious and contagious diseases like measles, tuberculosis, and chickenpox. If you have been around someone who has one of these conditions, please be very cautious, as these diseases are highly contagious, and you might catch these infections Preflunase 0.055% Nasal Spray makes you more prone to infections.

Preflunase 0.055% Nasal Spray should be used in dose and duration as prescribed by your doctor. The most common side effects are nasal ulceration, headache, shortness of breath, soreness, or dryness inside the nose. If these effects appear and are bothersome, call your doctor. Try to stay away from dust as it might worsen your symptoms, and also avoid smoking. Inform your doctor if you have or have ever had nose surgery, injury, or nose sores.

Do not use Preflunase 0.055% Nasal Spray if you are allergic to glucocorticoids or Fluticasone furoate. If you are pregnant or breastfeeding, consult your doctor before using this medicine. Before using Preflunase 0.055% Nasal Spray, please tell your doctor if you have or have ever had glaucoma (an eye disease), cataracts (clouding of the lens of the eye), herpes infection of the eye (sore on the eyelid or eye surface), asthma (sudden episodes of shortness of breath, and trouble breathing). Also, tell your doctor if you have (TB, a type of lung infection), chickenpox, measles, or tuberculosis. Do not use Preflunase 0.055% Nasal Spray in children below six years old.

Uses of Preflunase 0.055% Nasal Spray

Treatment of Nasal allergic symptoms (allergic rhinitis).

Directions for Use

• Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.• Insert the tip of the bottle into a nostril while closing the other nostril and spray towards the sides of the nostril. Keep your head straight and breathe gently. Repeat the same process for another nostril if needed.• When not in use, keep the bottle closed tightly and upright.

Medicinal Benefits

Preflunase 0.055% Nasal Spray is a glucocorticoid that helps to treat inflammation (redness and swelling) and allergies. Preflunase 0.055% Nasal Spray works by blocking certain chemical messenger's production that causes inflammation (redness and swelling) and allergies. As a result, the Preflunase 0.055% Nasal Spray provides relief from the discomfort and irritation in the nose caused due to allergies.

How Preflunase 0.055% Nasal Spray Works

Preflunase 0.055% Nasal Spray is a glucocorticoid that helps treat nasal allergy symptoms. It works by blocking certain chemical messengers present in the brain, causing pain, inflammation (swelling), and allergies. As a result, the Preflunase 0.055% Nasal Spray provides relief from the discomfort and irritation in the nose caused due to allergies.

Storage

Keep it out of the sight and reach of children.
Side effects of Preflunase 0.055% Nasal Spray 12 ml
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • A blocked nose can be relieved by drinking more water, which helps clear fluids.
  • Use saline nasal spray available over the counter to relieve blockage or blow harder to remove the mucus.
  • Use nasal strips that can be placed on the nose to widen nostrils and increase airflow.
  • Keep a humidifier around to moisten air at home/workplace.
  • Throat pain can worsen if there is no proper rest for your throat.
  • Drink plenty of warm fluids and frequently gargle with salt water.
  • Humidify the surrounding air using a humidifier, as dry air may increase dryness and throat pain.
  • Consider taking lozenges or hard candy throat pain relievers, which give a soothing effect.
  • Take enough rest and stay in warm places to reduce pain quickly.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • Get plenty of rest and avoid activities that tire you out to allow your body fight the infection.
  • Drink lots of fluids to help loosen mucus in the lungs.
  • Use over-the-counter medications like paracetamol or ibuprofen to manage fever.
  • Use a humidifier as it helps soothe irritated airways.
  • Do not make changes to your medication schedule or take over-the-counter medicines without consulting your doctor.
  • To keep your vocal cords lubricated and hydrated, drink lots of water.
  • Suck on ice chips, popsicles, or lozenges to clear your throat and reduce hoarseness.
  • Your voice cords may be soothed and healed by honey's antibacterial and anti-inflammatory properties.
  • Gargle with salt water.
  • Using a steam humidifier or inhaling steam might help minimize hoarseness and release mucus.
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.

What if I have taken an overdose of Preflunase 0.055% Nasal Spray

Though an overdose of Preflunase 0.055% Nasal Spray is not expected to cause life-threatening symptoms, it is advised to avoid exceeding the recommended dose. Long-term use may cause cataracts, glaucoma, skin thinning, changes in body fat, easy bruising, increased acne or facial hair, impotence or loss of interest in sex, and menstrual problems. Seek immediate medical attention if you experience these symptoms or suspect you have overdosed.

Drug Warnings

Inform your doctor if you have or have ever had nose surgery, injury, or nose sores. Before using Preflunase 0.055% Nasal Spray, please inform your doctor if you have or have ever had glaucoma (an eye disease), cataracts (clouding of the lens of the eye), herpes infection of the eye (an infection that causes a sore on the eyelid or eye surface), asthma (sudden episodes of wheezing, shortness of breath, and trouble breathing). Also, tell your doctor if you have (TB, a type of lung infection), chickenpox, measles, or tuberculosis. If you have been around someone who has one of these conditions, as these diseases are highly contagious, and Preflunase 0.055% Nasal Spray makes you more prone to infections. As a precautionary measure, please stay away from dust to help relieve your symptoms more quickly. Before using Preflunase 0.055% Nasal Spray, inform your doctor if you have ever had diabetes or a weak immune system. After using Preflunase 0.055% Nasal Spray, speak to your doctor immediately if you notice serious side effects such as facial pain, painful swallowing, eye pain, white patches in the nose/back of your throat, or persistent sore throat. Do not use Preflunase 0.055% Nasal Spray at the same time as other nasal sprays containing steroid medication.

Drug-Drug Interactions

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FluticasoneMifepristone
Critical
FluticasoneMibefradil
Severe

Drug-Drug Interactions

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FluticasoneMifepristone
Critical
How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
Co-administration of Preflunase 0.055% Nasal Spray 12 ml with Mifepristone may make Preflunase 0.055% Nasal Spray 12 ml less effective as a therapy.

How to manage the interaction:
Taking Preflunase 0.055% Nasal Spray 12 ml with Mifepristone is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
FluticasoneMibefradil
Severe
How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
Co-administration of Mibefradil may significantly increase the absorption of Preflunase 0.055% Nasal Spray 12 ml into the bloodstream.

How to manage the interaction:
Taking Preflunase 0.055% Nasal Spray 12 ml with Mibefradil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - swelling, weight gain, high blood pressure, high blood sugar, weak muscles, feeling down, acne, thinning skin, easy bruising, irregular periods, too much facial or body hair, unusual fat distribution, infection, injury, or a bad asthma attack - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
FluticasoneDesmopressin
Severe
How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
Co-administration of Desmopressin with Preflunase 0.055% Nasal Spray 12 ml may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
If you have to use Desmopressin and Preflunase 0.055% Nasal Spray 12 ml together, a doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact a doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.
FluticasoneTelithromycin
Severe
How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
When Preflunase 0.055% Nasal Spray 12 ml is taken with Telithromycin, it can lower the rate at which Telithromycin is broken down in the body.

How to manage the interaction:
Although there is a possible interaction between Preflunase 0.055% Nasal Spray 12 ml and Telithromycin, you can take these medicines together if prescribed by a doctor. If you notice any of these symptoms - swelling, weight gain, high blood pressure, high blood sugar, weak muscles, feeling down, acne, thinning skin, easy bruising, irregular periods, too much facial or body hair, strange fat distribution, bruising, infection, or a bad asthma attack - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
FluticasoneKetoconazole
Severe
How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
Co-administration of Ketoconazole and Preflunase 0.055% Nasal Spray 12 ml may significantly increase the absorption of Preflunase 0.055% Nasal Spray 12 ml into the bloodstream.

How to manage the interaction:
If you are supposed to take Preflunase 0.055% Nasal Spray 12 ml and Ketoconazole together, doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as weight gain, high blood pressure, swelling, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.
FluticasoneClarithromycin
Severe
How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
Co-administration of Preflunase 0.055% Nasal Spray 12 ml with Clarithromycin may significantly increase the absorption of Preflunase 0.055% Nasal Spray 12 ml into the blood stream.

How to manage the interaction:
Co-administration of Clarithromycin and Preflunase 0.055% Nasal Spray 12 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneItraconazole
Severe
How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
Coadministration of Itraconazole and Preflunase 0.055% Nasal Spray 12 ml may significantly increase the absorption of Preflunase 0.055% Nasal Spray 12 ml into the bloodstream.

How to manage the interaction:
Preflunase 0.055% Nasal Spray 12 ml and itraconazole may interact, but if a doctor prescribes them, you can still use them. Swelling, high blood pressure, high blood sugar, muscle weakness, depression, acne, stretch marks, easy bruising, bone density loss, cataracts, irregular menstruation, and excessive face or body hair growth are all signs that you need to consult a doctor. Never discontinue taking a medication without consulting a doctor.
FluticasoneTroleandomycin
Severe
How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
Co-administration of Troleandomycin may significantly increase the absorption of Preflunase 0.055% Nasal Spray 12 ml and tend to increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Preflunase 0.055% Nasal Spray 12 ml and Troleandomycin, but it can be taken if prescribed by a doctor. If you notice any of these symptoms - swelling, weight gain, high blood pressure, high blood sugar, muscle weakness, feeling down, acne, thinning skin, bruises, changes in your period, too much facial or body hair, unusual fat distribution, infection, injury, or a bad asthma attack - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
FluticasoneNelfinavir
Severe
How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
Taking Nelfinavir may increase the absorption of Preflunase 0.055% Nasal Spray 12 ml into the bloodstream and increase the risk of side effects.

How to manage the interaction:
If you are supposed to take Preflunase 0.055% Nasal Spray 12 ml and Nelfinavir together, a doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as weight gain, high blood pressure, swelling, high blood sugar, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.
FluticasoneVoriconazole
Severe
How does the drug interact with Preflunase 0.055% Nasal Spray 12 ml:
Co-administration of Preflunase 0.055% Nasal Spray 12 ml with Voriconazole may increase the absorption of Preflunase 0.055% Nasal Spray 12 ml into the bloodstream and increase the risk of side effects.

How to manage the interaction:
Although Preflunase 0.055% Nasal Spray 12 ml and Voriconazole can cause an interaction, they can be taken if prescribed by a doctor. However, if you experience swelling, muscle weakness, excessive growth of facial or body hair contact a doctor. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and balanced diet, and make sure you sleep at least 8 hours a day for a speedy recovery.

  • Please avoid contact with dust as it might worsen your symptoms.

  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil.

  • Also, please avoid contact with pollen present in the air, as it might worsen your symptoms.

  • Contact with any person who has chickenpox, measles, tuberculosis should be avoided as it might cause you the same infection as Preflunase 0.055% Nasal Spray makes your body prone to infections.

Habit Forming

No

Therapeutic Class

GLUCOCORTICOIDS

Preflunase 0.055% Nasal Spray Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Safe if prescribed

No interaction is found. But as a precautionary measure, limit or avoid alcohol consumption.

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Pregnancy

Caution

Preflunase 0.055% Nasal Spray should only be used during pregnancy if the mother's expected benefits outweigh the possible risks to the unborn child.

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Breast Feeding

Caution

It is not known whether Preflunase 0.055% Nasal Spray is secreted in breast milk. A Preflunase 0.055% Nasal Spray should only be used during breastfeeding if the mother's expected benefit outweighs the child's possible risk.

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Driving

Safe if prescribed

Preflunase 0.055% Nasal Spray does not affect your driving ability.

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Liver

Caution

Preflunase 0.055% Nasal Spray should be used with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust the dose if required based on your condition.

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Kidney

Safe if prescribed

It is generally safe to be used if you have kidney problems. However, before using Preflunase 0.055% Nasal Spray, consult your doctor.

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Children

Caution

Preflunase 0.055% Nasal Spray is not recommended for children below the age of six years. Proper dose monitoring is required in children above the age of six years by a child specialist.

Have a query?

FAQs

Preflunase 0.055% Nasal Spray is used to treat allergic rhinitis symptoms (inflammation of the nose's inner mucous membrane), such as sneezing, runny nose, and sinus discomfort.

Preflunase 0.055% Nasal Spray works by blocking certain chemical messengers' production that causes inflammation (redness and swelling) and allergies. As a result, the Preflunase 0.055% Nasal Spray provides relief from the discomfort and irritation in the nose caused due to allergies.

Studies have shown that using inhaled glucocorticoids for the long term in children like Preflunase 0.055% Nasal Spray can reduce linear growth. Prolonged exposure to Preflunase 0.055% Nasal Spray may lead to bone thinning. Preflunase 0.055% Nasal Spray might obstruct calcium absorption and inhibit bone cell growth. Your doctor will monitor your child's growth during the treatment with Preflunase 0.055% Nasal Spray. Inform your doctor if you observe any abnormality in your child's growth.

Preflunase 0.055% Nasal Spray may make your blood glucose levels high. Hence treatment with Preflunase 0.055% Nasal Spray is cautiously administered in patients with diabetes. Please monitor your blood glucose levels regularly and inform your doctor so the dose can be adjusted accordingly.

Use the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

Preflunase 0.055% Nasal Spray may cause dry mouth as a temporary side effect in some people. These side effects are not common for all. However, to avoid such side effects, drink plenty of water, regularly rinse your mouth, practice good oral hygiene and suck on sugarless candy. However, if the condition persists or worsens, please consult a doctor.

Preflunase 0.055% Nasal Spray is generally considered safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. To avoid negative complications, it's important to follow your doctor's instructions and inform them of any pre-existing medical conditions or medication history. To avoid negative complications, avoid exceeding the recommended dose and duration of it.

Generally, it is safe to use Preflunase 0.055% Nasal Spray daily if your doctor prescribes it. In fact, for conditions like allergies or chronic sinus issues, daily use is often recommended to manage symptoms effectively. However, prolonged or excessive use without medical supervision can lead to side effects. It's important to follow your doctor's instructions and not exceed the recommended dosage.

The commonly reported side effects of Preflunase 0.055% Nasal Spray that may occur in some individuals are nasal ulceration, headache, shortness of breath, soreness, or dryness inside the nose. If these symptoms worsen, please consult a doctor for relief.

It may be due to Preflunase 0.055% Nasal Spray, which, in rare cases, may cause a severe allergic reaction, even though it is designed to treat allergies. Symptoms may include rash, hives, difficulty breathing, or swelling of the face, throat, or tongue. If your friend experienced such symptoms, it is crucial to stop using Preflunase 0.055% Nasal Spray. Seek medical attention to find the underlying cause and get appropriate treatment.

No, Preflunase 0.055% Nasal Spray is unlikely to cause chickenpox, but it may weaken the immune system, worsening existing infections, so your brother should consult his doctor immediately to find the underlying cause and get appropriate treatment.

The duration of using Preflunase 0.055% Nasal Spray depends on the individual's condition status. Some individuals may be prescribed it for a few weeks, while others might need it for longer periods to control chronic symptoms. Follow the prescribed schedule and consult your doctor if you have concerns or wish to adjust treatment. Never discontinue Preflunase 0.055% Nasal Spray without medical guidance to avoid potential complications.

Long-term use of Preflunase 0.055% Nasal Spray may cause side effects like nose irritation, nosebleeds, infections, or a slightly weakened immune system. Rarely, it could affect hormones or increase the risk of eye issues like cataracts or glaucoma. Always follow your doctor's advice and report unusual symptoms.

Thrush is a type of fungal infection caused by Candida that typically affects the mouth, throat, or nasal passages. As Preflunase 0.055% Nasal Spray contains corticosteroids, it may increase the risk of developing thrush. If you notice any symptoms of thrush, such as white patches or soreness, consult your doctor for proper evaluation and treatment.

No, Preflunase 0.055% Nasal Spray is not recommended for treating a runny nose and sneezing due to the common cold. It's typically used for allergies. Consult your doctor for proper guidance.

Country of origin

India
Other Info - PRE1131

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:46 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.6439.pdf
  2. https://www.webmd.com/drugs/2/drug-148273/fluticasone furoate-furoate-nasal/details
  3. https://arthritis-research.biomedcentral.com/articles/10.1186/ar1372#:~:text=Glucocorticoids%20decrease%20gastrointestinal%20calcium%20absorption,decoy%20receptor%20for%20receptor%20activator
  4. https://www.drugs.com/mtm/fluticasone furoate-nasal.html
  5. https://www.jacionline.org/article/S0091-6749(98)70035-1/fulltext#:~:text=Five%20inhaled%20glucocorticoids%20are%20approved,%2C%20triamcinolone%20acetonide%2C%20and%20flunisolide.

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