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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Cadee Formulations

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Pregacad Capsule

Pregacad Capsule is a prescription medication used primarily to treat neuropathic pain, which is nerve pain caused by damage or disease affecting the nervous system. This type of pain commonly occurs in conditions such as diabetic neuropathy, shingles, or spinal disorders and may cause burning, stabbing, shooting, or tingling sensations.

This medicine works by helping to reduce abnormal pain signals transmitted by damaged nerves while also providing nutrients that support nerve health and recovery. As a result, it may help improve comfort, mobility, and overall quality of life in people living with chronic nerve-related pain.

To get the best results, take this medicine consistently at the times recommended by your doctor. It can be taken with or without food, although taking it with a meal may help reduce stomach discomfort in some people. Regular physical activity, good blood sugar control (if you have diabetes), and a balanced diet can also support nerve health and treatment outcomes.

Some people may experience common side effects such as drowsiness, dizziness, dry mouth, or mild swelling of the hands and feet. These effects are usually temporary. However, contact your doctor immediately if you develop severe swelling, significant mood changes, breathing difficulties, or unexplained muscle pain.

Do not take this medicine if you are allergic to any of its ingredients. Before starting treatment, tell your doctor if you have kidney disease, heart problems, depression, or other mental health conditions, as your treatment plan may require additional monitoring or dose adjustments.

Alcohol can increase the drowsiness and dizziness caused by this medicine and may raise the risk of falls or accidents. Inform your doctor about all medicines, supplements, and herbal products you are taking to help avoid potential interactions.

In India, pregabalin-containing medicines are available only on a doctor's prescription and should be used strictly under medical supervision. If you are pregnant, breastfeeding, or an older adult, consult your doctor before starting treatment to ensure it is appropriate for your individual circumstances.
 

Uses of Pregacad Capsule

This medicine is commonly prescribed to manage nerve-related pain and support nerve health in various conditions, including:

  • Neuropathic Pain: Helps reduce abnormal pain signals sent by damaged nerves in conditions such as diabetic neuropathy and postherpetic neuralgia (long-lasting nerve pain that can occur after a shingles infection).
  • Diabetic Neuropathy: Supports nerve health in people with diabetes while helping relieve burning, tingling, numbness, and discomfort caused by nerve damage.
  • Nutritional Deficiencies: Provides essential vitamins that support healthy nerve function and may help address vitamin deficiencies associated with certain nerve disorders.
     

Key Benefits

This medicine offers multiple benefits by relieving nerve pain while supporting nerve health and function, including:

  • Pain Relief: This medicine helps reduce burning, tingling, shooting, and stabbing nerve pain by calming overactive nerve signals.
  • Improved Daily Mobility: By reducing persistent nerve discomfort, it may help you move more comfortably and participate more easily in everyday activities.
  • Better Sleep Quality: Relief from nerve pain can reduce night-time discomfort and help improve sleep quality.
  • Support for Nerve Health: The vitamin and antioxidant components help support normal nerve function and recovery.
     

Directions for Use

To get the safest and most effective results from this medicine, follow these instructions:

  • Swallow the capsule whole with a full glass of water.
  • Do not crush, chew, or break the capsule, as this may affect how the medicine is released and absorbed.
  • Take it at the same times each day to help maintain consistent levels of the medicine in your body.


Important: Always follow your doctor's exact instructions regarding when and how to take this medicine. Do not change your dose or stop treatment suddenly without consulting your doctor first.
 

How Pregacad Capsule Works

Pregacad Capsule contains pregabalin, methylcobalamin, alpha lipoic acid, pyridoxine, and folic acid, which work together to relieve nerve pain and support nerve health. Pregabalin is an anticonvulsant and neuropathic pain-relieving medicine that binds to specific calcium channels in the nervous system. This reduces the release of certain neurotransmitters involved in pain signalling and helps calm overactive nerves, thereby reducing nerve pain and discomfort. Methylcobalamin is an active form of Vitamin B12 that helps maintain and repair nerve cells. It supports the production of myelin, the protective covering around nerve fibres, which helps nerves transmit signals more efficiently. Alpha lipoic acid is a potent antioxidant that helps protect nerve cells from damage caused by free radicals. It may also support healthy blood flow to nerve tissues, contributing to nerve function and recovery. Pyridoxine, also known as Vitamin B6, plays an important role in maintaining normal nerve function. It helps in the production of neurotransmitters, which are chemical messengers that allow nerve cells to communicate effectively. Folic acid is a B-vitamin that supports cell growth and repair. It contributes to the maintenance and regeneration of healthy nerve tissues and helps support overall nerve health. Together, these actions help reduce nerve pain, protect nerve cells from damage, support nerve repair, and promote healthy nerve function.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Pregacad Capsule as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Pregacad Capsule ; your doctor will decide whether Pregacad Capsule can be taken by breastfeeding mothers or not.

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Driving

Caution

Pregacad Capsule may cause drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Pregacad Capsule should not be given to children as the safety and efficacy have not been established.

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Heart

Consult your doctor

Please consult your doctor before using Pregacad Capsule if you have pre-existing heart problems. Your doctor will prescribe Pregacad Capsule if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before giving Pregacad Capsule to geriatric patients. Your doctor will prescribe Pregacad Capsule if the benefits outweigh the risks.

What if I have taken an overdose of Pregacad Capsule

Do not take more than the prescribed dose of Pregacad Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Manage Blood Sugar Levels: If your nerve pain is linked to diabetes, keeping your blood sugar within your target range is crucial to prevent further nerve damage.
  • Care for Your Feet: Inspect your feet daily for cuts, blisters, or redness, as nerve damage can reduce your ability to feel minor injuries, potentially leading to infections.
  • Incorporate B-Vitamin Rich Foods: Eat a balanced diet containing whole grains, lean meats, eggs, and leafy green vegetables to support the natural nerve-healing properties of Pregacad Capsule .
  • Engage in Low-Impact Exercise: Regular, gentle activities like walking, swimming, or stretching can improve blood circulation to your limbs and help ease chronic nerve discomfort.
     

Have a query?

How Soon It Starts Working

The time required for Pregacad Capsule to start to work: The time required for Pregacad Capsule to show its action is unknown. The time for which the effects of Pregacad Capsule last: The duration of action for Pregacad Capsule is unknown.

What if you forget to take Pregacad Capsule

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

• Store Pregacad Capsule at room temperature, ideally between 15°C and 30°C (59°F to 86°F), in a dry place away from direct sunlight • Do not store this medicine in damp areas like bathroom cabinets.

Drug Warnings

  • Do Not Stop Suddenly: Stopping Pregacad Capsule abruptly can cause withdrawal symptoms like anxiety, insomnia, sweating, or a return of your pain. Talk to your doctor about gradually decreasing your dose or tapering off safely.
  • Inspect Your Capsules: Before taking your medicine, inspect the packaging and the capsule. Do not use it if the capsule is damaged, cracked, or shows signs of moisture damage.
  • Avoid Dangerous Tasks: This medicine can cause dizziness or drowsiness. Avoid driving, operating heavy machinery, or performing tasks that require full alertness until you know how Pregacad Capsule affects you.
  • Prevent Falls: Be extra careful when standing up from a sitting or lying position, especially when you first start taking this medicine, as dizziness can increase your risk of falling.
     

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Drug-Drug Interactions

Pregacad Capsule may interact with certain medications, potentially increasing side effects or affecting treatment outcomes, including:

  • CNS Depressants and Opioids: Taking Pregacad Capsule with medicines like oxycodone, morphine, or certain sleeping pills can increase the risk of severe drowsiness, dizziness, and breathing difficulties.
  • Certain Diabetes Medications: Combining this medicine with medications like pioglitazone or rosiglitazone may increase the risk of weight gain or fluid retention (swelling).


Drug-Food Interactions

Certain foods and beverages may affect the safety of Pregacad Capsule . For example:

  • Alcohol: Avoid consuming alcohol while taking Pregacad Capsule , as it can dangerously intensify the sedative effects, leading to extreme sleepiness, dizziness, or lack of coordination.


Drug-Disease Interactions

Certain medical conditions may require special precautions when using Pregacad Capsule , such as:

  • Kidney Disease: Since this medicine is primarily cleared by the kidneys, people with reduced kidney function may require a lower dose to avoid a buildup of the drug in the body.
  • Heart Failure: Use with caution if you have a history of congestive heart failure, as some components of Pregacad Capsule may cause fluid retention, which can worsen your symptoms.
  • Depression or Mental Health Issues: This medicine may increase the risk of suicidal thoughts or behaviour; discuss this risk with your doctor if you have a history of depression.
     

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Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

FAQs

Pregacad Capsule is used in the management of neuropathic pain.

Pregacad Capsule may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.

To treat your condition effectually, continue taking Pregacad Capsule for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Pregacad Capsule ; your doctor will reduce the dose gradually.

Pregacad Capsule can cause life-threatening breathing problems in patients with COPD and asthma. So a person with long paused breathing, blue coloured lips, or sleeping disorder should inform the doctor before use of Pregacad Capsule .

Pregacad Capsule can decrease the sperm count and may affect men's fertility. However, it is unclear whether these effects would occur. So it is advisable to ask your doctor about your risk.

No, Pregacad Capsule is not a usual painkiller but is used in the management of neuropathic pain by providing essential nutrients to the nerves.

Pregacad Capsule contains Pregabalin, Methylcobalamin, Alpha-lipoic acid, Pyridoxine, and Folic acid. Pregabalin affects the chemicals in the brain that send pain signals to the nervous system, thereby relieving nerve pain. Methylcobalamin and Pyridoxine help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Folic acid helps in delivering essential nutrients to the nerves. Together, Pregacad Capsule provides relief from neuropathic pain.

Yes, Pregacad Capsule may make you feel drowsy or you cause you to fall asleep suddenly during your daily activities. Sometimes, you might not even feel sleepy or have any other warning signs before you fall asleep suddenly. Thus, avoid driving or operating machinery, working at heights or participating in potentially dangerous activities until you know how Pregacad Capsule affects you. If you experience such episodes while taking Pregacad Capsule , inform your doctor.

Pregacad Capsule may rarely cause serious side effects such as allergic reaction, suicidal thoughts or swelling of limbs (legs, hands, or feet). If you experience any signs of these side effects, discontinue Pregacad Capsule and consult your doctor. Signs of an allergic reaction include swelling of your face, lips, mouth, tongue, gums, and neck. Allergic reactions can also lead to skin rash, difficulty breathing, hives (raised bumps) or blisters. Watch out for any changes, especially sudden changes in behaviors, mood, thoughts or feelings, or if you have suicidal thoughts.

It may take about 2 weeks to experience the first benefit with Pregacad Capsule . However, to see full effect, it may take around 2-3 months or it may take longer in some patients.

If you forget to take a dose of Pregacad Capsule , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue your regular dose. Do not double the dose to make up for the missed one as this may increase the risk of side effects.

If you suspect you have taken too much of Pregacad Capsule , please contact your doctor immediately. Do this even if you have no signs of discomfort or poisoning.

No, taking a higher than the recommended dose may not be more effective, rather it may increase the risk of toxicity and serious side effects. If your symptoms are not relieved or there is an increased severity of your symptoms after using the recommended doses, please consult your doctor.

You are advised to avoid alcohol consumption while taking Pregacad Capsule as it may increase the severity of dizziness and sleepiness. However, if you have any concerns, please discuss with your doctor.

If you have started taking Pregacad Capsule , you may need to see your doctor regularly. However, if the recommended doses does not improve your symptoms or if the side effects persist or worsen which affect your routine activities, consult your doctor.

Store Pregacad Capsule at room temperature in a cool and dry place. Protect from light and moisture. Keep it out of reach of children.

The side effects of Pregacad Capsule include sleepiness, dizziness, drowsiness, tiredness, nausea and vomiting. If these side effects persist or worsen, please consult your doctor.

Some people may begin to notice an improvement in their symptoms within a few weeks, but it can take longer for the full therapeutic effect to develop. Nerve recovery is a gradual process. Talk to your doctor if you do not feel any improvement after a few weeks.

Yes, you can take Pregacad Capsule with or without food. If you experience mild stomach upset when taking it, try taking it with a meal. Talk to your doctor if your stomach upset continues.

Yes, drowsiness and dizziness are among the most common side effects of Pregacad Capsule , especially when you first start taking it. Avoid driving or operating machinery until you know how this medicine affects you. Talk to your doctor if these feelings persist.

No, you should not stop taking Pregacad Capsule suddenly even if you feel better. Stopping the medicine abruptly can lead to withdrawal symptoms such as sleep problems, headaches, or a return of your nerve pain. Talk to your doctor, who will guide you on how to gradually reduce your dose safely.

It is highly recommended to avoid alcohol while taking Pregacad Capsule . Alcohol can worsen the medicine's side effects, leading to severe drowsiness, confusion, and a higher risk of accidental falls. Talk to your doctor if you have concerns about alcohol use.

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and return to your normal routine. Do not take two doses at the same time to make up for a missed one. Talk to your doctor or pharmacist if you have questions.

Pregacad Capsule is generally not recommended during pregnancy or breastfeeding unless your doctor decides that the benefits outweigh the potential risks to the baby. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before starting this medication.

Yes, Pregacad Capsule can interact with certain pain medications, especially strong prescription pain relievers like opioids, which can cause severe drowsiness or dangerous breathing problems when taken together. Always give your doctor or pharmacist a complete list of all medications you are currently taking.

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Country of origin

India
Other Info - PRE1707
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