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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Pregalin 150 Capsule is used in the prevention of neuropathic pain, epilepsy (seizure episodes), fibromyalgia (musculoskeletal pain), and neuralgia (pain due to damaged/irritated nerve). It contains Pregabalin, which works by calming the damaged or overactive nerves in the body that may cause nerve or musculoskeletal pain or seizures. Besides this, it also decreases the number of pain signals sent out by damaged nerves in the body. It may cause side efffects such as dizziness, somnolence (sleepiness/drowsiness), dry mouth, oedema (fluid overload with swelling), blurred vision, weight gain and abnormal thinking (difficulty with concentration/attention). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

PREGABALIN-150MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pregalin 150 Capsule

Pregalin 150 Capsule belongs to a group of medications called 'anti-convulsants', primarily used in the prevention of neuropathic pain, epilepsy (seizure episodes), fibromyalgia (musculoskeletal pain), and neuralgia (pain due to damaged/irritated nerve). Neuropathic pain is chronic nerve pain usually caused by damaged nerves due to a variety of diseases like diabetes, shingles (viral infection that causes a painful rash), spinal cord injury, and injuries to tissue, muscles, or joints.

Pregalin 150 Capsule contains 'Pregabalin', which works by calming the damaged or overactive nerves in the body that may cause nerve or musculoskeletal pain or seizures. Besides this, it also decreases the number of pain signals sent out by damaged nerves in the body.

In some cases, Pregalin 150 Capsule might cause side effects like dizziness, somnolence (sleepiness/drowsiness), dry mouth, oedema (fluid overload with swelling), blurred vision, weight gain and abnormal thinking (difficulty with concentration/attention). Most of these side effects do not require medical attention. However, if the side effects persist or worsen, consult a doctor.

Tell your doctor if you are facing symptoms of suicidal ideation or behaviour, drug addiction, chronic pulmonary insufficiency, muscle pain, soreness, weakness, kidney, liver, or heart diseases.  Caution is required before giving Pregalin 150 Capsule to pregnant or breastfeeding women. The safety and effectiveness in children less than 18 years of age have not been established, so Pregalin 150 Capsule should not be given to them.

Uses of Pregalin 150 Capsule

Pregalin 150 Capsule is used in the treatment of Neuropathic pain, Epilepsy (seizures/fits) and Fibromyalgia (musculoskeletal pain). The detailed uses of Pregalin 150 Capsule are as follows:
• Neuropathic Pain Relief: Pregalin 150 Capsule is frequently recommended to treat nerve pain caused by conditions like postherpetic neuralgia or diabetes.
• Epilepsy management: It helps regulate seizure activity and can be used as an adjuvant therapy for people with partial seizures.
• Generalized Anxiety Disorder (GAD): Pregalin 150 Capsule reduces excessive worry and relaxes the nervous system to treat anxiety problems.
• Fibromyalgia Treatment: It could enhance general quality of life by reducing the pervasive pain and suffering brought on by fibromyalgia.
• Post-Traumatic Stress Disorder (PTSD): In order to help manage the symptoms of Post-Traumatic Stress Disorder (PTSD), Pregalin 150 Capsule can be administered to relieve anxiety and related conditions.

Directions for Use

Tablet/capsule: Swallow it as a whole with a glass of water. Do not crush, chew, or break it. Oral solution/Syrup: Shake the bottle well before use. Take the prescribed dose with the help of a measuring cup/dosing syringe/dropper.

Medicinal Benefits

Pregalin 150 Capsule belongs to a group of medications called 'anticonvulsants' used to prevent neuropathic pain (pain due to damaged nerves), fibromyalgia (musculoskeletal pain), and epilepsy (fits). It works by calming the damaged or overactive nerves in the body that may cause pain or seizures, thereby decreasing the number of pain signals sent out by damaged nerves in the body.

How Pregalin 150 Capsule Works

Pregalin 150 Capsule contains 'Pregabalin', which works by calming the damaged or overactive nerves in the body that may cause nerve or musculoskeletal pain or seizures. Besides this, it also decreases the number of pain signals sent out by damaged nerves in the body.

Storage

Store in a cool and dry place away from sunlight
Side effects of Pregalin 150 Capsule
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.

What if I have taken an overdose of Pregalin 150 Capsule

Do not take more than the prescribed dose of Pregalin 150 Capsule as it may cause overdose. The symptoms of overdose include sleepiness, confusion,agitation, restlessness, fits and coma. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Pregalin 150 Capsule if you are known to be allergic to any of its contents. Inform your doctor if you have symptoms of suicidal ideation or behaviour, drug addiction, chronic lung diseases, muscle weakness, heart problems, liver/kidney impairment. Caution is required before giving Pregalin 150 Capsule to pregnant or breastfeeding women. The safety and effectiveness of Pregalin 150 Capsule in children under 18 years of age have not been established, so Pregalin 150 Capsule should not be given to them. Taking Pregalin 150 Capsule with opioids analgesics or painkillers like oxycodone can cause respiratory failure, coma, and even leading to death, so avoid its intake together. If you are taking any sleeping pills or tranquillizers, tell your doctor about this as Pregalin 150 Capsule interacts with these drugs and causes sleepiness, drowsiness and dizziness and affects your daily activity. Immediately contact a doctor if you have swelling of your face, mouth, tongue, lips, gums, neck, or throat (angioedema).

Drug-Drug Interactions

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PregabalinKetamine
Severe
PregabalinBuprenorphine
Severe

Drug-Drug Interactions

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PregabalinKetamine
Severe
How does the drug interact with Pregalin 150 Capsule:
Taking Ketamine with Pregalin 150 Capsule may increase the risk of side effects.

How to manage the interaction:
Although taking Pregalin 150 Capsule and ketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as dizziness, drowsiness, confusion, difficulty concentrating, breathing difficulty, consult the doctor. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinBuprenorphine
Severe
How does the drug interact with Pregalin 150 Capsule:
Using Pregalin 150 Capsule together with Buprenorphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Buprenorphine and Pregalin 150 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinEsketamine
Severe
How does the drug interact with Pregalin 150 Capsule:
When Pregalin 150 Capsule and Esketamine are taken together, it may increase the risk of side effects.

How to manage the interaction:
Although taking Pregalin 150 Capsule and Esketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinPethidine
Severe
How does the drug interact with Pregalin 150 Capsule:
Using Pregalin 150 Capsule together with Pethidine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pethidine and Pregalin 150 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinButorphanol
Severe
How does the drug interact with Pregalin 150 Capsule:
Using Pregalin 150 Capsule together with Butorphanol causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Butorphanol and Pregalin 150 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinPentazocine
Severe
How does the drug interact with Pregalin 150 Capsule:
Using Pregalin 150 Capsule together with Pentazocine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pentazocine and Pregalin 150 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinFentanyl
Severe
How does the drug interact with Pregalin 150 Capsule:
Using Pregalin 150 Capsule together with Fentanyl can increase the risk of side effects.

How to manage the interaction:
Although taking fentanyl together with Pregalin 150 Capsule can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you have dizziness, sleepiness, difficulty concentrating, or impairment in judgment. Do not stop taking any medication without consulting a doctor.
PregabalinTapentadol
Severe
How does the drug interact with Pregalin 150 Capsule:
Using Tapentadol together with Pregalin 150 Capsule may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Pregalin 150 Capsule with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not exceed the doses or frequency and duration of use advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinNalbuphine
Severe
How does the drug interact with Pregalin 150 Capsule:
Using Pregalin 150 Capsule together with Nalbuphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Nalbuphine and Pregalin 150 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinSodium oxybate
Severe
How does the drug interact with Pregalin 150 Capsule:
Using Sodium oxybate together with Pregalin 150 Capsule may increase the risk of side effects.

How to manage the interaction:
Although taking Pregalin 150 Capsule with Sodium oxybate together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience drowsiness, dizziness, lightheadedness, confusion, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination, consult the doctor. For at least six hours after taking sodium oxybate, avoid operating machinery or engaging in potentially dangerous activities. Also, be careful when getting up from a sitting or lying down posture. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a diet rich in fruits, vegetables, whole grains, omega-3 rich foods. Avoid fried foods, high-fat dairy products, pastries, and processed foods, as they may worsen neuropathic pain.

  • Do regular exercise and maintain a healthy weight.

  • Avoid the consumption of alcohol as it may increase dizziness or drowsiness.

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT

Pregalin 150 Capsule Substitute

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Alcohol

Unsafe

It is unsafe to consume alcohol since it may worsen the side effects like dizziness and sleepiness.

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Pregnancy

Caution

Pregalin 150 Capsule is a category C pregnancy drug. Please consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing Pregalin 150 Capsule .

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Breast Feeding

Caution

Pregalin 150 Capsule should be used in breastfeeding women only when prescribed by a doctor. Your doctor will weigh the benefits and potential risks before prescribing Pregalin 150 Capsule .

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Driving

Caution

Do not drive or operate machinery if you experience dizziness or drowsiness while using Pregalin 150 Capsule . Pregalin 150 Capsule can also sometimes cause blurry/double vision; hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Take Pregalin 150 Capsule with caution, especially if you have or had a history of liver disease/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Pregalin 150 Capsule with caution, especially if you have or had a history of kidney disease/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Pregalin 150 Capsule is not recommended for children below the age of 18 years. The safety and efficacy of Pregalin 150 Capsule have not been established.

Have a query?

FAQs

Pregalin 150 Capsule is primarily used in the prevention of neuropathic pain, epilepsy (seizure episodes), fibromyalgia (musculoskeletal pain), and neuralgia (pain due to damaged/irritated nerve).

Pregalin 150 Capsule works by blocking the pain centre that interferes with pain messages that travel through the brain and spine (central nervous system). In epilepsy, it prevents episodes of fits by reducing the abnormal electrical activity in the brain and calming the overactive nerves.

Yes, Pregalin 150 Capsule may cause weight gain because it increases your hunger. However, regular physical exercise and a balanced diet with low-calorie food may help you keep your weight stable. Please consult the doctor if you have any further concerns about keeping your weight stable.

No, you are not recommended to take Pregalin 150 Capsule with tramadol as co-administration of these medicines may cause breathing problems, drowsiness, and even lead to a stage of coma. So, before using Pregalin 150 Capsule with painkillers like oxycodone or any other opioid analgesics, you are advised to contact your doctor so that the dosage may be adjusted accordingly to use safely.

No, Pregalin 150 Capsule is not a normal painkiller. It is an anti-convulsant that helps treat neuropathic pain, musculoskeletal pain, and epilepsy.

Do not discontinue Pregalin 150 Capsule without consulting your doctor as it might cause withdrawal symptoms. The doctor will reduce the dose gradually to prevent withdrawal symptoms.

Neuropathic pain occurs due to nerve damage while muscle pain occurs due to spasms or injury. Neuropathic pain is chronic and is felt as tingling and burning sensation. Whereas, muscle pain is a dull ache and will generally get better within a few days unless it is a severe injury.

Pregalin 150 Capsule works in different ways for each disease. For neuropathic and musculoskeletal pain, it calms the damaged or overactive nerves and decreases pain signals sent out by damaged nerves in the body. In case of epilepsy, it reduces abnormal electrical activity in the brain.

Pregalin 150 Capsule starts working within a week and you may notice its full benefits in a few weeks. Continue taking Pregalin 150 Capsule for the prescribed duration for effective results.

Pregalin 150 Capsule should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.

Pregalin 150 Capsule may be addictive. Therefore, take Pregalin 150 Capsule only for the prescribed duration. Do not take Pregalin 150 Capsule for a prolonged time as it may lead to mental or physical dependence.

Taking Pregalin 150 Capsule with diazepam may increase side effects such as dizziness, confusion, drowsiness and difficulty concentrating. Hence, consult the doctor before taking diazepam with Pregalin 150 Capsule .

Pregalin 150 Capsule may cause side effects like dizziness, somnolence (sleepiness/drowsiness), dry mouth, oedema (fluid overload with swelling), blurred vision, weight gain and abnormal thinking (difficulty with concentration/attention). Most of these side effects do not require medical attention. However, if the side effects persist or worsen, consult a doctor.

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - PRE0002

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