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Manufacturer/Marketer :

Akshaya Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pregasafe Tablet

Pregasafe Tablet is a combination medication indicated for the management of neuropathic pain. It may also be used to treat pain caused by fibromyalgia (musculoskeletal pain), nerve pain in post-herpetic neuralgia (damage to the nerve fibres during shingles infection) or spinal cord injury. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. 

Pregasafe Tablet contains Methylcobalamin, Pregabalin, Alpha lipoic acid, and Pyridoxine. Mecobalamin/Methylcobalamin, a form of vitamin B12, regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Pregabalin is an antiepileptic agent that works by binding to the specific site on voltage-gated calcium channels, thus helping to relieve nerve pain. Alpha-lipoic acid is an antioxidant that prevents cell damage and restores vitamin levels in the body. It also decreases pain and numbness in neuropathy. Pyridoxine (vitamin B6) is a water-soluble vitamin that is involved in protein, fat, and carbohydrate metabolism and the formation of red blood cells and neurotransmitters. 

Your doctor will decide the dosage based on your medical condition. Sometimes, Pregasafe Tablet may have common side effects like dizziness, drowsiness, blurred vision, shakiness, headache, nausea, vomiting, constipation, weight gain, swelling in the hands and feet, and dry mouth. These side effects do not require medical attention and gradually resolve over time. However, talk to your doctor if you experience these side effects persistently.

Please tell your doctor if you are allergic to Pregasafe Tablet or its components. It is also essential to let your doctor know if you are pregnant, planning to conceive, or a breastfeeding mother. Pregasafe Tablet may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Pregasafe Tablet , as it could lead to increased dizziness and sleepiness. Pregasafe Tablet should be used in children only with the doctor's advice.

Uses of Pregasafe Tablet

Pregasafe Tablet is used in the treatment of neuropathy, pain in fibromyalgia, and nerve pain in post-herpetic neuralgia. The detailed uses of Pregasafe Tablet are as follows:

  • Manages neuropathy: Pregasafe Tablet helps relieve nerve pain, tingling, and numbness caused by nerve damage in conditions like diabetic neuropathy.
  • Reduces fibromyalgia pain: Pregasafe Tablet eases widespread muscle and joint pain associated with fibromyalgia, improving daily activities.
  • Treats nerve pain after shingles: Pregasafe Tablet helps control persistent nerve pain that follows a shingles infection (post-herpetic neuralgia) by protecting and calming damaged nerves.

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Directions for Use

  • Pregasafe Tablet can be taken with or without food as advised by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Pregasafe Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

Medicinal Benefits

Pregasafe Tablet contains Methylcobalamin, Pregabalin, Alpha lipoic acid, and Pyridoxine. Methylcobalamin regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Pregabalin works by binding to the specific site on voltage-gated calcium channels, thus helping to relieve nerve pain. Alpha-lipoic acid decreases pain and numbness in neuropathy. It helps lower blood sugar levels and protects the nerves from damage in diabetic neuropathy. Pyridoxine is involved in the formation of red blood cells and neurotransmitters. It also relieves nerve pain and corrects the nerve impulse transmission process.

How Pregasafe Tablet Works

Pregasafe Tablet contains Methylcobalamin, Pregabalin, Alpha lipoic acid, and Pyridoxine. Mecobalamin/Methylcobalamin, a form of vitamin B12, regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Pregabalin is an antiepileptic agent that works by binding to the specific site on voltage-gated calcium channels, thus helping to relieve nerve pain. Alpha-lipoic acid is an antioxidant that prevents cell damage and restores vitamin levels in the body. It also decreases pain and numbness in neuropathy. Pyridoxine (vitamin B6) is a water-soluble vitamin that is involved in protein, fat, and carbohydrate metabolism and the formation of red blood cells and neurotransmitters.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Cold chain - To be stored in cold places at 2ºC to 8ºC.
Side effects of Pregasafe Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Blood flow to the brain and the rest of the body is increased by physical activity. This could help you maintain your memory.
  • Reading, solving puzzles, and picking up new skills are examples of mental workouts that can keep the brain engaged and enhance memory retention.
  • Maintaining an active social life enhances memory and brain stimulation.
  • Relaxation methods like yoga, meditation, and deep breathing can help because long-term stress can affect memory.
  • Drink plenty of water and stay hydrated.
  • Limit the intake of alcohol and caffeine.
  • Maintain good hygiene habits.
  • Avoid holding on and empty the bladder at regular intervals.
  • Try to quit smoking.

What if I have taken an overdose of Pregasafe Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Pregasafe Tablet may include dermatoses, diarrhoea, dizziness, fatigue or weakness, Headache, Nausea, peripheral neuropathy, photosensitivity, tingling sensation in hands and feet, and vomiting. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Let your doctor know if you have any blood disorders, chronic obstructive pulmonary disease (COPD), liver/kidney/heart diseases, diabetes, mood disorders, substance use disorder, and angioedema (painless swelling under the skin) before starting Pregasafe Tablet . Pregnant and breastfeeding women should consult their doctor before taking Pregasafe Tablet . This medicine may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol during the treatment, as it could increase dizziness and sleepiness. Pregasafe Tablet should be used in children only with the doctor's advice.

Drug-Drug Interactions

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PregabalinDezocine
Severe
PregabalinHydrocodone
Severe

Drug-Drug Interactions

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PregabalinDezocine
Severe
How does the drug interact with Pregasafe Tablet:
Using Pregasafe Tablet together with Dezocine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Dezocine and Pregasafe Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinHydrocodone
Severe
How does the drug interact with Pregasafe Tablet:
Using Pregasafe Tablet together with Hydrocodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydrocodone and Pregasafe Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinPethidine
Severe
How does the drug interact with Pregasafe Tablet:
Using Pregasafe Tablet together with Pethidine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pethidine and Pregasafe Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinSodium oxybate
Severe
How does the drug interact with Pregasafe Tablet:
Using Sodium oxybate together with Pregasafe Tablet may increase the risk of side effects.

How to manage the interaction:
Although taking Pregasafe Tablet with Sodium oxybate together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience drowsiness, dizziness, lightheadedness, confusion, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination, consult the doctor. For at least six hours after taking sodium oxybate, avoid operating machinery or engaging in potentially dangerous activities. Also, be careful when getting up from a sitting or lying down posture. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregasafe Tablet:
When Tramadol is used with Pregasafe Tablet, it may possibly lead to side effects such as respiratory difficulties, unconsciousness.

How to manage the interaction:
Although taking tramadol and Pregasafe Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinOxycodone
Severe
How does the drug interact with Pregasafe Tablet:
Using Pregasafe Tablet together with Oxycodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking oxycodone and Pregasafe Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregasafe Tablet:
Using Pregasafe Tablet together with Butorphanol causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Butorphanol and Pregasafe Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinSufentanil
Severe
How does the drug interact with Pregasafe Tablet:
Using Pregasafe Tablet together with Sufentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking sufentanil and Pregasafe Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinCodeine
Severe
How does the drug interact with Pregasafe Tablet:
Using Pregasafe Tablet together with Codeine may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Codeine and Pregasafe Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregasafe Tablet:
Taking Ketamine with Pregasafe Tablet may increase the risk of side effects.

How to manage the interaction:
Although taking Pregasafe Tablet and ketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as dizziness, drowsiness, confusion, difficulty concentrating, breathing difficulty, consult the doctor. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try Vitamin B complex food sources like milk, cheese, eggs, liver and kidney, chicken, red meat, tuna, mackerel, salmon, shellfish, oysters, clams, dark green vegetables, such as spinach and kale, beets, avocados, potatoes, whole grains, cereals, kidney beans, black beans, and chickpeas.
  • Include cayenne pepper in your diet to help lower neuropathic pain.
  • Taking a warm shower can help ease the pain.
  • Avoid smoking and alcohol consumption.
  • Using essential oils for massage can help increase circulation.
  • Exercise regularly and maintain a healthy lifestyle. Avoid excess fatty foods.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Pregasafe Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

Avoid consumption of alcohol while taking Pregasafe Tablet as it may cause increased dizziness and sleepiness.

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Pregnancy

Caution

Pregasafe Tablet should be used in pregnancy only if prescribed by a doctor. Let your doctor know if you are pregnant or planning to conceive before taking Pregasafe Tablet .

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Breast Feeding

Caution

Pyridoxine is excreted into the breast milk. Please consult your doctor before taking Pregasafe Tablet if you are a nursing mother.

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Driving

Unsafe

Pregasafe Tablet causes dizziness, drowsiness, and blurred vision and may interfere with your driving ability. Do not drive or operate machinery if you are not mentally alert and focused.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Pregasafe Tablet . Dose adjustments may be necessary.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Pregasafe Tablet . Your doctor may adjust the dose based on your condition.

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Children

Caution

Pregasafe Tablet should be used in children only when a doctor advises. The doctor will prescribe the dosage based on the child's age and weight.

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Heart

Let your doctor know if you have any history of heart diseases. Your doctor will weigh the benefits and potential risks before prescribing Pregasafe Tablet .

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Geriatrics

Safe if prescribed

Pregasafe Tablet is generally safe for elderly patients. However, please consult your doctor if you have any concerns.

FAQs

Pregasafe Tablet is used to treat Neuropathy, pain in fibromyalgia (musculoskeletal pain), and nerve pain in post-herpetic neuralgia (damage to the nerve fibres during shingles infection).

Pregasafe Tablet affects the chemicals in the brain that send pain signals to the nervous system, thereby relieving nerve pain. It also reduces further nerve damage in neuropathy and aids in nerve regeneration.

People taking Pregasafe Tablet should be closely monitored for suicidal thoughts or behaviour. Do not hesitate to speak with your doctor immediately if you experience suicidal tendencies.

Pyridoxine in Pregasafe Tablet may interfere with a urine test for urobilinogen. Please ensure your doctor and the laboratory staff know you take Pregasafe Tablet before undergoing blood and urine examinations.

Country of origin

INDIA

Manufacturer/Marketer address

No 4 Thayappa Reddy Layout, Anathapura Road, Bangalore, Karnataka India - 560064
Other Info - PRE0329

Disclaimer

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