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Pregator Capsule is a combination medicine used to manage neuropathic pain due to damaged nerves. This medicine works by altering the nerve signals that cause pain and thereby protects nerve fibres. It helps provide a protective effect on the nerve tissues and the brain. You may experience common side effects like dizziness, sleepiness, tiredness, headache, nausea, vomiting, dry mouth, and constipation.

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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

ALPHA LIPOIC ACID-200MG+FOLIC ACID-1.5MG+METHYLCOBALAMIN-1500MCG+PREGABALIN-75MG+PYRIDOXINE HYDROCHLORIDE-3MG

Manufacturer/Marketer :

Micro Labs Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Pregator Capsule

Pregator Capsule is a prescription medicine used to treat long-term nerve pain, also known as neuropathic pain, which is caused by conditions like diabetes or shingles. It works by calming overactive nerves in the body and providing key nutrients that help repair nerve fibres. By targeting both the pain signals and nerve health, it helps manage chronic discomfort effectively.

To get the best results, you should take Pregator Capsule regularly and at the same times each day as directed by your doctor. This oral medicine can be taken with or without food. Combining this treatment with daily lifestyle adjustments, such as keeping your blood sugar stable and doing gentle, low-impact exercise, can significantly improve your physical comfort.

While taking Pregator Capsule , you might experience mild side effects like drowsiness or dizziness. These are common as your body adjusts to the medication, but you must contact your doctor immediately if you experience serious symptoms like swelling in your hands or feet, unexpected muscle pain, or sudden mood changes.

Talk to your doctor before starting this medicine if you have kidney problems, a history of heart issues, or any mood disorders. Do not take this medicine if you have had an allergic reaction to any of its components in the past.

This medicine can interact with alcohol, which can make you feel extremely sleepy and lightheaded. Always inform your pharmacist about other medications you are taking, especially sleeping pills or muscle relaxants, and consult your doctor if you are pregnant, breastfeeding, or planning a pregnancy.

Uses of Pregator Capsule

Pregator Capsule is used to treat neuropathic pain. The detailed uses of Pregator Capsule are as follows:

  • Neuropathic pain: Pregator Capsule helps calm hyperactive nerve pathways, relieving burning, shooting, or throbbing pain.
  • Diabetic neuropathy: It targets nerve damage caused by high blood sugar, reducing tingling and numbness in the hands and feet.
  • Nerve health support: It supplies essential nutrients that aid in rebuilding the damaged outer protective layer of your nerves.

Key Benefits

Pregator Capsule provides targeted relief that helps you return to your daily activities with less discomfort. By addressing both the pain signals and the underlying nerve health, it offers a comprehensive approach to managing chronic nerve conditions.

  • Reduces shooting and burning sensations: By stabilising nerve activity, it eases the persistent discomfort that interferes with daily tasks.
  • Supports nerve repair: It delivers specific vitamins and antioxidants that assist the body in maintaining and repairing nerve structures.
  • Improves sleep quality: Lowering nighttime nerve pain helps you fall asleep more easily and sleep more deeply.
Side effects of Pregator Capsule
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Blood flow to the brain and the rest of the body is increased by physical activity. This could help you maintain your memory.
  • Reading, solving puzzles, and picking up new skills are examples of mental workouts that can keep the brain engaged and enhance memory retention.
  • Maintaining an active social life enhances memory and brain stimulation.
  • Relaxation methods like yoga, meditation, and deep breathing can help because long-term stress can affect memory.
  • Drink plenty of water and stay hydrated.
  • Limit the intake of alcohol and caffeine.
  • Maintain good hygiene habits.
  • Avoid holding on and empty the bladder at regular intervals.
  • Try to quit smoking.

Directions for Use

  • Pregator Capsule can be taken with or without food.
  • It is advised to take Pregator Capsule as advised by a doctor.
  • Swallow the Pregator Capsule as a whole with a glass of water.
  • Do not chew, crush or break it.

How Pregator Capsule Works

Pregator Capsule works through the combined action of its key active ingredients, which target nerve pain and support nerve health through different mechanisms. The first component, pregabalin, is the primary pain-relieving medicine in this combination. It binds to the alpha-2-delta subunit of voltage-gated calcium channels in the brain and spinal cord. This reduces the release of excitatory neurotransmitters involved in pain signalling, helping to calm overactive nerves and relieve neuropathic pain. The second component, methylcobalamin, is the active form of vitamin B12. It is essential for the formation and maintenance of myelin, the protective sheath surrounding nerve fibres, helping support normal nerve function and repair. The third component, alpha lipoic acid, is a potent antioxidant. It helps reduce oxidative stress, supports blood flow to peripheral nerves, and may help protect nerves from further damage. Folic acid supports normal DNA synthesis, cell division, and the formation of healthy red blood cells. It also contributes to normal nerve function by supporting cellular repair and regeneration. Pyridoxine hydrochloride (vitamin B6) plays an important role in nerve metabolism by supporting the synthesis of neurotransmitters and helping maintain normal nerve function. Together, these ingredients help relieve neuropathic pain while supporting overall nerve health.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Pregator Capsule as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Pregator Capsule ; your doctor will decide whether Pregator Capsule can be taken by breastfeeding mothers or not.

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Driving

Caution

Pregator Capsule causes drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Pregator Capsule should not be given to children as the safety and efficacy have not been established.

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Heart

Consult your doctor

Inform your doctor if you have a history of heart disease. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Pregator Capsule should be given to elderly patients only if prescribed by a doctor. If you have any concerns about using Pregator Capsule in geriatrics, please consult your doctor.

What if I have taken an overdose of Pregator Capsule

If you suspect an overdose, seek immediate emergency medical attention. Symptoms of an overdose may include severe sleepiness, confusion, or agitation.

Diet & Lifestyle Advise

  • Manage blood sugar levels: If you have diabetes, keeping your blood sugar within your target range is the most effective way to prevent further nerve damage.
  • Inspect your feet daily: Nerve damage can reduce your ability to feel pain, so check your feet regularly for any cuts, blisters, or redness.
  • Stay active safely: Engage in gentle, low-impact exercises like walking or swimming to improve blood circulation and reduce nerve pain.
  • Avoid smoking: Smoking narrows your blood vessels, which can reduce blood supply to your peripheral nerves and worsen symptoms.
health query

Have a query?

How Soon It Starts Working

The time required for Pregator Capsule to start to work: The time required for Pregator Capsule to show its action is unknown. The time for which the effects of Pregator Capsule last: The duration of action for Pregator Capsule is unknown.

What if you forget to take Pregator Capsule

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a forgotten one.

Storage

•Store Pregator Capsule at room temperature, ideally between 15°C and 30°C (59°F and 86°F).•Keep this and all other medications safely out of the reach of children and pets. Do not freeze the medicine.

Drug Warnings

  • Do not drive, operate heavy machinery, or perform dangerous tasks until you know how Pregator Capsule affects your alertness, as it commonly causes sleepiness.
  • Avoid stopping this medication suddenly. Your doctor will help you safely stop by gradually decreasing your dose over at least a week to prevent withdrawal symptoms.
  • Be mindful of your mental health. If you, your family, or your caregivers notice sudden changes in your mood, worsening depression, or unusual behaviour, contact your doctor immediately.
  • Always inform any dentist or surgeon that you are taking Pregator Capsule before scheduling any medical or dental procedures

Drug-Drug Interactions

verifiedApollotooltip
  • Taking Pregator Capsule with other medicines that cause drowsiness—such as sleeping pills, narcotic pain relievers, muscle relaxants, or anxiety medications—can severely increase sleepiness and slow down your breathing.
Pregabalin + Mecobalamin + Thioctic acid + Pyridoxine (vit b6) + Folic acidNalbuphine
Severe
Pregabalin + Mecobalamin + Thioctic acid + Pyridoxine (vit b6) + Folic acidFluorouracil
Severe

Drug-Drug Interactions

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Pregabalin + Mecobalamin + Thioctic acid + Pyridoxine (vit b6) + Folic acidNalbuphine
Severe
How does the drug interact with Pregator Capsule:
Using Pregator Capsule together with Nalbuphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Nalbuphine and Pregator Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired-judgment, reaction time, motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
Pregabalin + Mecobalamin + Thioctic acid + Pyridoxine (vit b6) + Folic acidFluorouracil
Severe
How does the drug interact with Pregator Capsule:
Co-administration of Pregator Capsule with Fluorouracil may increase the risk of side effects including anemia(low number of red blood cells), bleeding problems, infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between Pregator Capsule and Fluorouracil, you can take these medicines together if prescribed by a doctor. However, if you experience vomiting, diarrhea, paleness of skin, unexpected bleeding or bruising, blood in the stools, fever, chills, body pains, skin reactions, mouth ulcers or sores, numbness, burning or tingling in your hands and feet, consult a doctor. Do not discontinue any medications without consulting a doctor.
Pregabalin + Mecobalamin + Thioctic acid + Pyridoxine (vit b6) + Folic acidOxycodone
Severe
How does the drug interact with Pregator Capsule:
Using Pregator Capsule together with Oxycodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking oxycodone and Pregator Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
Pregabalin + Mecobalamin + Thioctic acid + Pyridoxine (vit b6) + Folic acidBuprenorphine
Severe
How does the drug interact with Pregator Capsule:
Using Pregator Capsule together with Buprenorphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Buprenorphine and Pregator Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
Pregabalin + Mecobalamin + Thioctic acid + Pyridoxine (vit b6) + Folic acidRemifentanil
Severe
How does the drug interact with Pregator Capsule:
Using Pregator Capsule together with Remifentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking remifentanil and Pregator Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired-judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
Pregabalin + Mecobalamin + Thioctic acid + Pyridoxine (vit b6) + Folic acidButorphanol
Severe
How does the drug interact with Pregator Capsule:
Using Pregator Capsule together with Butorphanol causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Butorphanol and Pregator Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
Pregabalin + Mecobalamin + Thioctic acid + Pyridoxine (vit b6) + Folic acidHydrocodone
Severe
How does the drug interact with Pregator Capsule:
Using Pregator Capsule together with Hydrocodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydrocodone and Pregator Capsule together can result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
Pregabalin + Mecobalamin + Thioctic acid + Pyridoxine (vit b6) + Folic acidMethadone
Severe
How does the drug interact with Pregator Capsule:
Using Pregator Capsule together with Methadone causes central nervous system depression(a physiological state that can result in a decreased rate of breathing, decreased heart rate).

How to manage the interaction:
Although taking methadone and Pregator Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired- judgment, reaction time, motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
Pregabalin + Mecobalamin + Thioctic acid + Pyridoxine (vit b6) + Folic acidSufentanil
Severe
How does the drug interact with Pregator Capsule:
Using Pregator Capsule together with Sufentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking sufentanil and Pregator Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired-judgment, reaction time, and motor coordination, dizziness, sleepiness, difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
Pregabalin + Mecobalamin + Thioctic acid + Pyridoxine (vit b6) + Folic acidPentazocine
Severe
How does the drug interact with Pregator Capsule:
Using Pregator Capsule together with Pentazocine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pentazocine and Pregator Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Do not consume alcohol while taking Pregator Capsule , as it can significantly increase the risk of severe drowsiness, dizziness, and coordination issues.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Pregator Capsule is used in the treatment of Neuropathic pain.
Pregator Capsule contains Pregabalin, methylcobalamin, alpha-lipoic acid, pyridoxine hydrochloride, and folic acid. It affects the chemicals in the brain that send pain signals to the nervous system, thereby relieving nerve pain. Pregator Capsule also helps reduce further nerve damage in neuropathy. It works by improving blood circulation to peripheral body parts and thus relieving pain.
Do not discontinue Pregator Capsule without consulting your doctor as it could lead to withdrawal symptoms. To treat your condition effectually continue taking Pregator Capsule for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Pregator Capsule ; your doctor will reduce the dose gradually.
People taking Pregator Capsule should be closely monitored for suicidal thoughts or behaviour. Do not be reluctant to speak with your doctor immediately if you experience suicidal tendencies.
Pregator Capsule may decrease sperm count and may affect fertility in men. However, it is unclear whether these effects would occur. So it is advisable to ask your doctor about your risk.
No, Pregator Capsule is not a typical painkiller. Pregator Capsule is used to manage neuropathic pain.
To control weight gain associated with Pregator Capsule , you need to make changes in your diet and lifestyle. Avoid high-calorie foods like soft drinks, oily snacks, and sweets. Exercise regularly. Have a balanced diet and avoid alcohol consumption. Consult a doctor if you have any other concerns.
Yes, the use of Pregator Capsule can cause sleepiness or drowsiness. Avoid alcohol intake as it may increase sleepiness. This does not require any medical treatment as this will gradually reduce over time. Please consult the doctor if it persists for longer durations.
Serious side effects of Pregator Capsule are rare which includes allergic reactions, suicidal thoughts, or swelling of limbs. Stop using Pregator Capsule and contact your doctor if you notice any of these signs. Also, watch out for sudden mood changes, thoughts, behaviours, or feelings as these may be signs of suicidal thoughts.
Pregator Capsule may show initial improvement within 2 weeks, but full benefits typically appear after 2-3 months and may take longer for some patients based on their health condition. However, please consult the doctor if you do not notice any improvements.
If you forget to take Pregator Capsule , then take it as soon as you remember and if it is the time for the next dose, skip the missed dose and continue taking a regular dose. Avoid taking the double dose to make up for the forgotten one.
If you accidentally take too much of Pregator Capsule , seek medical attention immediately. Symptoms of Pregator Capsule overdose may include dizziness, drowsiness, confusion, and blurred vision.
No, higher than the recommended dose of Pregator Capsule will not be more effective, instead it can lead to increased side effects. Therefore, do not exceed the recommended dose. If your symptoms worsen, please consult your doctor.
You are recommended to avoid alcohol while taking Pregator Capsule , as it may cause excessive drowsiness or dizziness. Please, consult the doctor if you have any concerns.
If you begin taking Pregator Capsule , regular check-ups with your doctor may be necessary. However, consult your doctor if the prescribed dosage does not improve your symptoms or if you experience any side effects.
Store Pregator Capsule at a temperature below 25°C in a cool and dry place. Protect from light and moisture. Keep it out of reach of children. Pregator Capsule should be disposed, by following local guidelines or asking your pharmacist how to properly dispose of any unused medicine.
Pregator Capsule contains Methylcobalamin, Pregabalin, Folic acid, Pyridoxine hydrochloride and Alpha Lipoic acid as its active substances.
Take Pregator Capsule as directed by your doctor, with or without food. Swallow it whole with a glass of water. Do not crush, chew, or break it.
While using Pregator Capsule you are recommended to tell your doctor if you are allergic to its active components. Inform your doctor if you have heart issues, bipolar disorder, are pregnant, or breastfeeding. Pregator Capsule is not recommended for children, and alcohol should be avoided. Also inform your doctor, if you have suicidal thoughts or breathing issues, especially if you have COPD, asthma, or related conditions.
Pregator Capsule may interact with amitriptyline (anti-depressants), morphine and oxycodone (pain killer), phenobarbital (anti-consultants), diazepam (anti-anxiety), metformin (anti-diabetic), methotrexate (immunosuppressant), sulfasalazine (anti-rheumatoid), chloramphenicol(antibiotic), levodopa (anti-parkinsons). Therefore, consult your doctor before taking other medicines while on treatment with Pregator Capsule .
Yes, Pregator Capsule is designed for daily use as prescribed by your doctor. Taking it consistently at the same times every day helps manage chronic nerve pain effectively. Talk to your doctor if you have any concerns about long-term use.
No, Pregator Capsule is not a permanent cure for nerve damage, but it is highly effective at managing nerve pain symptoms and supporting the overall health and repair of your nerve pathways. Talk to your doctor to understand the long-term outlook for your condition.
Generally, standard pain relievers can be taken alongside Pregator Capsule , but you should always check with your doctor or pharmacist first to ensure there are no specific reasons why you should avoid them.
This medicine is generally not recommended during breastfeeding unless your doctor decides that the benefits outweigh the risks. Some of the active components can pass into breast milk. Talk to your doctor to explore safer alternatives.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

No. 28 Sundar Industrial Estate,N.T.Y Layout Mysore Road , Bangalore - 560026, India
Other Info - PRE0155

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