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Premala Capsule 10's is a combination medicine used in the treatment of neuropathic pain, and nutritional deficiencies. This medicine works by altering the nerve signals that cause pain and thereby protects nerve fibres. It helps provide a protective effect on the nerve tissues and the brain. You may experience common side effects like nausea, vomiting, diarrhoea, and stomach upset.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Infivis Life Care

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Premala Capsule 10's

Premala Capsule 10's is an oral prescription medication primarily used to manage neuropathic pain, which is chronic pain caused by nerve damage. It helps relieve the burning, stabbing, or tingling sensations often associated with conditions like diabetic neuropathy or shingles. By supporting nerve repair and calming overactive nerve signals, Premala Capsule 10's helps restore comfort to your daily life.

To get the best results, you should take Premala Capsule 10's consistently at the same times every day as directed by your doctor. It can be taken with or without food, though taking it with food may help prevent an upset stomach. Managing your blood sugar levels and staying physically active can also greatly support the healing process and enhance the medication's effectiveness.

While taking Premala Capsule 10's, you may experience mild side effects like dizziness, sleepiness, or dry mouth. These symptoms often improve as your body adjusts to the medication, but you must contact your healthcare provider immediately if you experience serious side effects such as sudden mood changes, severe swelling, or breathing difficulties.

Do not take this if you have a known allergy to pregabalin, mecobalamin, alpha lipoic acid, pyridoxine, folic acid, or any other ingredients in this capsule. Before starting this medication, talk to your doctor if you have kidney disease, heart problems, or a history of depression or substance misuse.

This medication can interact with other drugs, alcohol, and tobacco; for instance, drinking alcohol while on Premala Capsule 10's can dangerously increase drowsiness and impair your coordination. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly patient, consult your healthcare provider to ensure this treatment is safe for you.

Uses of Premala Capsule 10's

Premala Capsule 10's is used in the treatment of neuropathic pain and associated nerve disorders. The detailed uses of Premala Capsule 10's are as follows:

  • Neuropathic Pain: Premala Capsule 10's helps relieve nerve pain caused by conditions such as shingles, spinal cord injuries, or nerve compression.
  • Diabetic Neuropathy: It helps manage tingling, burning sensations, numbness, and pain in the hands and feet resulting from long-standing diabetes.
  • Peripheral Neuropathy: It helps support damaged nerves and may improve symptoms such as weakness, altered sensation, and discomfort associated with peripheral nerve disorders.
  • Nutritional Support for Nerve Health: It provides essential vitamins and antioxidants that help support nerve repair and maintain healthy nerve function.

Key Benefits

Premala Capsule 10's helps support nerve health and provides relief from nerve-related discomfort, helping improve daily functioning and overall quality of life. By supporting nerve repair and reducing symptoms, it promotes long-term neurological well-being.

Benefits may include:

  • Helps reduce nerve-related symptoms such as burning, shooting pain, tingling, and numbness.
  • Supports healthy nerve function and promotes nerve repair.
  • May improve sleep quality by reducing nighttime nerve discomfort.
  • Helps improve mobility, coordination, and comfort during daily activities.
  • Supports the regeneration and maintenance of healthy nerve tissue.
  • Promotes long-term nerve health and enhances overall physical well-being.

Directions for Use

  • Premala Capsule 10's can be taken with or without food, or as advised by the doctor.
  • Follow your doctor's instructions regarding dosage and timing to ensure optimal effectiveness.
  • Swallow Premala Capsule 10's as a whole with a glass of water.
  • Do not crush, chew, or break Premala Capsule 10's, as this may impact absorption.

How Premala Capsule 10's Works

Premala Capsule 10's contains Alpha Lipoic Acid, Folic Acid, Mecobalamin, Pyridoxine, and Pregabalin. Alpha Lipoic Acid: It is a powerful antioxidant that helps protect nerve cells from damage and improves blood flow to the nerves. It may help reduce symptoms such as burning, tingling, and numbness. Folic Acid: It is an essential vitamin that supports healthy cell growth, tissue repair, and the production of genetic material needed for normal nerve function and regeneration. Mecobalamin: It is an active form of vitamin B12 that helps repair damaged nerves and maintain the protective covering around nerve fibers, supporting healthy nerve function. Pyridoxine: Also known as vitamin B6, it helps support the nervous system and assists in the production of important chemical messengers involved in nerve signaling. Pregabalin: It helps calm overactive nerves and reduces the transmission of pain signals, helping relieve nerve pain and discomfort.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Premala Capsule 10's as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or planning for pregnancy; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Premala Capsule 10's if you are breastfeeding; your doctor will decide whether Premala Capsule 10's can be taken by breastfeeding mothers or not.

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Driving

Caution

Premala Capsule 10's may cause drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Premala Capsule 10's should not be given to children as the safety and efficacy have not been established.

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Heart

Caution

Premala Capsule 10's should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Premala Capsule 10's.

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Geriatrics

Caution

Premala Capsule 10's should be given with caution in elderly patients due to an increased risk of side effects. Please consult your doctor before using Premala Capsule 10's.

What if I have taken an overdose of Premala Capsule 10's

If you accidentally take too much of Premala Capsule 10's, seek immediate medical attention or call an emergency poison control center. Symptoms of an overdose may include extreme sleepiness, confusion, agitation, or restlessness.

Diet & Lifestyle Advise

  • Manage Your Blood Sugar: If you have diabetes, keep a close eye on your blood glucose levels. Stable blood sugar prevents further damage to your nerves and supports the healing action of the medication.
  • Eat a Nutrient-Rich Diet: Focus on foods rich in B-vitamins, such as leafy green vegetables, whole grains, eggs, and lean proteins, to support nerve repair.
  • Stay Active: Engage in gentle, low-impact exercises like walking, swimming, or stretching. Regular physical activity improves blood circulation, which helps deliver nutrients to your nerves.
  • Limit Alcohol Consumption: Avoid drinking alcohol, as it can directly damage nerves and worsen the drowsiness and dizziness caused by this medication.
  • Practice Foot Care: If you suffer from numbness, inspect your feet daily for any cuts, blisters, or sores to prevent infections that you might not feel due to reduced sensitivity.
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How Soon It Starts Working

The time required for Premala Capsule 10's to start to work: Premala Capsule 10's shows its action within 1 to 2 hours of administration. The time for which the effects of Premala Capsule 10's last: Premala Capsule 10's effect lasts for 12 to 24 hours.

What if you forget to take Premala Capsule 10's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store the medication at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Use caution during activities requiring alertness: ALPHA LIPOIC ACID+FOLIC ACID+MECOBALAMIN+PYRIDOXINE+PREGABALIN may cause significant dizziness and drowsiness. Avoid driving, riding a bicycle, operating machinery, or performing hazardous tasks until you know how the medicine affects you.
  • Do not stop treatment abruptly: Never stop taking this medicine suddenly, as it may cause withdrawal symptoms such as headache, nausea, sleep disturbances, and worsening pain. Your doctor will advise you on how to gradually reduce the dose if treatment needs to be discontinued.
  • Monitor your emotional health: Contact your doctor promptly if you experience unusual mood changes, worsening depression, anxiety, or thoughts of self-harm. Family members or caregivers should also be aware of these potential symptoms.
  • Discuss your medical history with your doctor: Tell your healthcare provider if you have a history of alcohol misuse, substance dependence, or drug abuse before starting treatment, as pregabalin may carry a risk of dependence in some individuals.
  • Monitor your weight and swelling: Check your weight regularly and contact your doctor if you notice rapid, unexplained weight gain or swelling of the hands, feet, or ankles.

verifiedApollotooltip
  • Medicines that cause drowsiness (e.g., opioid pain relievers, sleeping pills, anti-anxiety medicines): Taking these medicines alongside Premala Capsule 10's may increase drowsiness, dizziness, and the risk of breathing problems.
  • Blood pressure medicines (e.g., ACE inhibitors): Combining these with Premala Capsule 10's may increase the risk of swelling (edema) in the hands or feet.
  • Diabetes medicines (e.g., thiazolidinediones such as pioglitazone): Taking these medicines alongside Premala Capsule 10's may increase fluid retention and weight gain, especially in patients with heart conditions.

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  • Alcohol: Avoid consuming alcohol while taking Premala Capsule 10's, as it may cause excessive drowsiness, dizziness, and increase the risk of accidents or falls.
     

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Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Premala Capsule 10's is a combination medicine used to treat neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to damage to sensory nerves.
Premala Capsule 10's contains Pregabalin, mecobalamin, pyridoxine, alpha-lipoic acid and folic acid. Pregabalin works by binding to the specific site on voltage-gated calcium channels, this helps in relieving nerve pain. Mecobalamin and Pyridoxine help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Folic acid helps in providing essential nutrients to the nerves. Together, Premala Capsule 10's helps in providing relief from neuropathic pain.
Premala Capsule 10's is used to treat diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly causes pain in legs and feet.
Premala Capsule 10's may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.
Premala Capsule 10's may be used to treat fibromyalgia. Fibromyalgia is a condition which is characterised by musculoskeletal pain, tenderness, fatigue, sleep and mood issues.
Do not discontinue Premala Capsule 10's without consulting your doctor as it could lead to withdrawal symptoms. To treat your condition effectually continue taking Premala Capsule 10's for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Premala Capsule 10's.
Dry mouth could be a side-effect of Premala Capsule 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent mouth drying.
This medication is generally not recommended during pregnancy unless your doctor decides that the benefits outweigh the potential risks to the unborn baby. If you are pregnant, planning to become pregnant, or breastfeeding, discuss your options with your healthcare provider. Talk to your doctor.
You should avoid drinking alcohol while taking this medication. Alcohol can significantly worsen the drowsiness and dizziness caused by Premala Capsule 10's, increasing the risk of falls, injuries, and breathing problems. Talk to your doctor if you have concerns about alcohol use.
Yes, this medication can occasionally cause changes in mood, behavior, or thoughts of self-harm. It is important for you and your family to monitor your emotional state closely while taking it. If you notice severe anxiety, worsening depression, or unusual mood swings, seek medical help immediately. Talk to your doctor.
Take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your normal schedule. Do not take two doses at the same time to make up for a missed one. Talk to your doctor or pharmacist if you are unsure.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

249, T.V.Samy Road(East), Near Hotel Navaratna, R.S.Puram, Coimbatore - 641 002, Tamilnadu. Bangalore
Other Info - PRE2272
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