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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Premigrane-NS Tablet 2's is used to prevent migraine symptoms uch as headache, nausea, and vomiting. It contains two medicines, namely Sumatriptan and Naproxen. It may cause common side effects, such as dizziness, sleepiness, nausea, chest discomfort, dry mouth, irregular heartbeats, and heartburn.
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Manufacturer/Marketer :

BSA Pharma Inc

Consume Type :

Oral

Return Policy :

Not Returnable

About Premigrane-NS Tablet 2's

Premigrane-NS Tablet 2's is used to prevent migraine symptoms such as headache, nausea, and vomiting. Migraine is a neurological condition which is characterised by an intense pulsating, throbbing, pounding, debilitating headache which usually occurs on one side of the head; however, it can occur on both sides or shift. Hormonal changes, stress, bright lights, loud sounds, and certain foods and drinks can trigger migraine headaches. 

Premigrane-NS Tablet 2's is a combination of two drugs: Sumatriptan and Naproxen. Sumatriptan acts on the serotonin (5-HT) receptors located in the brain, thereby causing the narrowing of the brain's blood vessels, which in turn affects the blood flow patterns associated with headache. Naproxen is a painkiller which works by blocking the effect of chemical messengers that cause pain.  Thus, Premigrane-NS Tablet 2's prevents symptoms of migraine-like headache, nausea and vomiting. 
 
You are advised to take Premigrane-NS Tablet 2's as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as dizziness, sleepiness, nausea, chest discomfort, dry mouth, irregular heartbeats, and heartburn. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently. 

Consult your doctor if you are pregnant or breastfeeding. Premigrane-NS Tablet 2's should not be taken during the third trimester of pregnancy. Premigrane-NS Tablet 2's may cause drowsiness and dizziness, so drive with caution. Premigrane-NS Tablet 2's should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol with Premigrane-NS Tablet 2's as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects. 

Uses of Premigrane-NS Tablet 2's

Premigrane-NS Tablet 2's is used in the treatment of migraine. The detailed uses of Premigrane-NS Tablet 2's are as follows:

  • Treats Migraine Headaches: Premigrane-NS Tablet 2's effectively treats acute migraine attacks with or without aura by narrowing the swollen blood vessels around the brain and by blocking the effect of chemical messengers that cause pain.
  • Relieves Migraine-Associated Symptoms: Premigrane-NS Tablet 2's helps relieve symptoms such as nausea, vomiting, headache, and sensitivity to light and sound.

Have a query?

Directions for Use

  • Premigrane-NS Tablet 2's can be taken with or without food or as advised by a doctor.
  • It is advised to take Premigrane-NS Tablet 2's exactly as prescribed by your doctor, following the recommended dosage and duration to get optimal results.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

Key Benefits

Premigrane-NS Tablet 2's is a combination of two drugs, Sumatriptan and Naproxen. Premigrane-NS Tablet 2's is indicated for the acute treatment of migraine with or without aura. Sumatriptan is a serotonin receptor agonist that acts on the serotonin (5-HT) receptors located in the brain, which causes the narrowing of the brain's blood vessels, thereby affecting the blood flow patterns with a headache. Naproxen is a pain killer which works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. By blocking the effect of COX enzymes, fewer prostaglandins are produced, thereby reducing pain in migraine.

How Premigrane-NS Tablet 2's Works

Premigrane-NS Tablet 2's is a combination of two drugs: Sumatriptan and Naproxen. Sumatriptan acts on the serotonin (5-HT) receptors located in the brain, thereby causing the narrowing of the brain's blood vessels, which in turn affects the blood flow patterns associated with headache. Naproxen is a painkiller which works by blocking the effect of chemical messengers that cause pain.  Thus, Premigrane-NS Tablet 2's prevents symptoms of migraine-like headache, nausea and vomiting.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Premigrane-NS Tablet 2's

Do not take more than the prescribed dose of Premigrane-NS Tablet 2's as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Premigrane-NS Tablet 2's if you are allergic to any of its contents; if you have had any recent heart surgery or stroke, blood circulation problems, heart problems, narrowing of blood vessels to the stomach, legs, arms or kidneys, or uncontrolled high blood pressure; if you are taking MAO inhibitors, antidepressant or have taken them in the last 14 days; or if you have taken 5-HT agonists called triptan or ergotamine in the last 24 hours. Inform your doctor if you have high blood pressure, asthma, diabetes, epilepsy, overweight, heart, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Premigrane-NS Tablet 2's should not be taken during the third trimester of pregnancy. Premigrane-NS Tablet 2's may cause drowsiness and dizziness, so drive only if you are alert. Premigrane-NS Tablet 2's should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Premigrane-NS Tablet 2's as it could lead to increased drowsiness. Stop taking Premigrane-NS Tablet 2's and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. 

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.

  • Avoid bright lights, loud noise, and extreme temperatures.

  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.

  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.

  • Massage your scalp to ease the pain.

  • Lie down in a quiet, dark room.

  • Place a cold cloth over your forehead or neck.

  • Avoid smoking, alcohol, and caffeinated drinks. 

  • Learn what triggers your migraine and try avoiding them.

  • Stay hydrated. Drink plenty of fluids.

  • Learn relaxation skills as they help in reducing stress.

Habit Forming

No

Therapeutic Class

[ANTIMIGRAINE AGENTS]

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Premigrane-NS Tablet 2's as it may cause increased drowsiness.

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Pregnancy

Caution

Premigrane-NS Tablet 2's should be used during the first and second trimesters of pregnancy only if the benefits outweigh the risks. Premigrane-NS Tablet 2's should not be taken during the third trimester of pregnancy.

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Breast Feeding

Caution

Premigrane-NS Tablet 2's may pass into breastmilk and harm the baby. Please consult your doctor before taking Premigrane-NS Tablet 2's; your doctor will decide whether Premigrane-NS Tablet 2's can be taken by breastfeeding mothers or not.

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Driving

Caution

Premigrane-NS Tablet 2's may cause dizziness, weakness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Premigrane-NS Tablet 2's should not be given to children as the safety and effectiveness were not established.

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Heart

Unsafe

This medicine is not recommended in cardiac patients due to its adverse effects. However, if prescribed extreme caution should be exercised.

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Geriatrics

Unsafe

Premigrane-NS Tablet 2's is not safe for use in elderly patients due to its serious side effects.

FAQs

Premigrane-NS Tablet 2's is used to prevent migraine symptoms such as headache, nausea, and vomiting.

Premigrane-NS Tablet 2's contains Sumatriptan and Naproxen. Sumatriptan acts on the serotonin (5-HT) receptors located in the brain; this causes the narrowing of the blood vessels in the brain and also affects the blood flow patterns associated with headaches. Naproxen works by blocking the effect of chemical messengers that cause pain.

Dry mouth could be a side-effect of Premigrane-NS Tablet 2's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevents drying of the mouth.

Premigrane-NS Tablet 2's treats a headache that has already begun but does not prevent or reduce the attacks. Premigrane-NS Tablet 2's should not be used to treat cluster headache or other types of headache, which may cause loss of movement on one side of the body.

Premigrane-NS Tablet 2's contains Naproxen, an NSAID. Therefore, consult your doctor before taking any pain killer medicines, fever-reducing medicines, medicines for cold or sleeping problems along with Premigrane-NS Tablet 2's as they may also contain NSAID.

Talk to your doctor before taking Premigrane-NS Tablet 2's with anti-hypertensive medicines as they may cause impaired response when taken with painkiller. Regular monitoring of blood pressure levels is advised while taking Premigrane-NS Tablet 2's if you have high blood pressure. Premigrane-NS Tablet 2's should not be taken if you have uncontrolled high blood pressure.

Premigrane-NS Tablet 2's contains painkiller, which might increase the risk of gastrointestinal adverse effects such as ulceration, bleeding, and perforation of intestines or stomach. Therefore, consult your doctor if you have stomach ulcers.

Do not take a dose higher than the recommended dose of Premigrane-NS Tablet 2's. Taking more can lead to serious side effects like heart attack, stroke, bleeding, and stomach ulcers. Always follow your doctor's instructions. If your migraines persist, consult your doctor for a revised treatment plan to avoid harmful self-medication.

Store Premigrane-NS Tablet 2's in its original container, keeping it cool, dry, and out of sunlight. Keep it out of the reach of children. Regularly check the expiration date. When you need to dispose of the medicine, remove the label, place it in a plastic bag, and throw it away in the household trash. Remember, never flush the medicine down the toilet or sink to prevent harm to others and the environment.

Premigrane-NS Tablet 2's can cause sleepiness as a common side effect. Drowsiness affects up to 30% of naproxen users and 17% of sumatriptan users. Combining these medications may increase sedative effects. To minimize sleepiness, take the medication as directed, avoid operating heavy machinery or driving, and consider taking it at bedtime if prescribed once daily. If sleepiness persists or worsens, consult your doctor.

You can stop taking Premigrane-NS Tablet 2's once your migraine symptoms are relieved. However, always follow your doctor's instructions and consult them before stopping or adjusting the medication. If migraines persist, consult your doctor for further guidance.

Various factors, including stress, hormonal changes, certain foods, sleep disturbances, physical exertion, weather changes, and medical conditions can trigger migraines. Common triggers include chocolate, cheese, citrus fruits, bright lights, and loud noises. Identifying and managing your personal triggers can help reduce migraine frequency and severity.

The common side effects of Premigrane-NS Tablet 2's include dizziness, sleepiness, nausea, chest discomfort, dry mouth, irregular heartbeat, and heartburn. These side effects are usually mild and temporary, resolving as your body adjusts to the medication. However, if any side effects persist or worsen, it's essential to consult your doctor for proper guidance and care.

Premigrane-NS Tablet 2's should be used only during the first and second trimesters of pregnancy if the benefits outweigh the risks. Premigrane-NS Tablet 2's should not be taken during the third trimester of pregnancy.

Premigrane-NS Tablet 2's should not be given to children as safety and effectiveness were not established.

Migraine is a neurological condition which is characterised by an intense, debilitating headache. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, and certain foods and drinks can trigger migraine headaches.

Taking more than the recommended dosage does not provide additional pain relief and can increase the risk of adverse effects.

Country of origin

India

Manufacturer/Marketer address

S.C.O : C-21B, Dholkot, Ambala, Haryana 134003
Other Info - PRE2548

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