Prexx 500 mg Injection 1's
MRP ₹4895
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₹734.3 Cashback (15%)
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About Prexx 500 mg Injection
Prexx 500 mg Injection belongs to the group of medicines called folate analogue metabolic inhibitors used alone or in combination with other anti-cancer medicines to treat non-small cell lung cancer and malignant pleural mesothelioma (cancer affecting the lining of the lung).
Prexx 500 mg Injection contains Pemetrexed, which works by blocking the action of substances that may help the cancer cells multiply.
In some cases, Prexx 500 mg Injection may cause side effects such as diarrhoea, tiredness, nausea, vomiting, and loss of appetite. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
Do not use Prexx 500 mg Injection if you are pregnant or breastfeeding. Prexx 500 mg Injection is not recommended for children below 18 years. Women and men should use effective contraception during treatment with Prexx 500 mg Injection and for 6 and 3 months afterwards. Inform your doctor about your health condition and medications to rule out any side effects/interactions.
Uses of Prexx 500 mg Injection
Prexx 500 mg Injection is used in the treatment of Non-small cell lung cancer and malignant pleural mesothelioma. The detailed uses of Prexx 500 mg Injection are as follows:
- Non-Small Cell Lung Cancer (NSCLC): Prexx 500 mg Injection is used alone or in combination with other agents for advanced or metastatic NSCLC, especially in patients who are not candidates for surgery.
- Malignant Pleural Mesothelioma: Prexx 500 mg Injection is often combined with cisplatin to treat this aggressive cancer affecting the lining of the lungs.
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Directions for Use
- Follow your doctor’s instructions on the dosage and timing of this medication.
- Prexx 500 mg Injection will be administered by a nurse or doctor.
- Do not self-administer.
Medicinal Benefits
Prexx 500 mg Injection contains Pemetrexed, which belongs to the group of medicines called anti-folate anti-neoplastic agents indicated in the treatment of malignant pleural mesothelioma and non-small cell lung cancer in initial treatment in combination with cisplatin, as maintenance treatment of patients whose disease has not progressed after four cycles of platinum-based first-line chemotherapy and after prior chemotherapy as a single agent. Prexx 500 mg Injection treats cancer by blocking the action of substances that may help the cancer cells multiply.
How Prexx 500 mg Injection Works
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- Rest well; get enough sleep.
- Eat a balanced diet and drink enough water.
- Manage stress with yoga and meditation.
- Limit alcohol and caffeine.
- Physical activities like walking or jogging might help boost energy and make you feel less tired.
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
- Preventing Vomiting (Before it Happens)
- Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
- Having a small meal before taking your medication can help reduce nausea and vomiting.
- Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
- Managing Vomiting (If it Happens)
- Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
- What to Do if Vomiting Persists
- Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
- Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
- Avoid contact with people who are sick.
- Wash your hands regularly with soap and water.
- Avoid unpasteurized dairy products.
- Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
- Get sufficient sleep and manage stress which helps in improving white blood cell count.
- Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
- Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
- Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
- Consume vitamin C-rich foods as they aid iron absorption.
- Limit tea, cocoa, and coffee as these can slow iron absorption.
- Exercise regularly; however, do not overdo it.
What if I have taken an overdose of Prexx 500 mg Injection
Drug Warnings
Do not use Prexx 500 mg Injection if you are allergic to any of its components, pregnant or breastfeeding, or if you have taken or plan to receive yellow fever vaccination. Inform the doctor if you have/had heart disease, kidney problems, have had or are going to have radiation therapy, or have accumulation of fluid around the lungs. Seek immediate medical attention if you experience symptoms of fever or infection; pain, sores, redness or swelling in the mouth; chest pain or a fast heartbeat; allergic reaction (skin rash, burning/prickling sensation, or fever); Stevens-Johnson Syndrome or toxic epidermal necrolysis (severe rash, itching, or blistering); low haemoglobin levels (tiredness, feeling faint, paleness, or becoming easily breathless); low platelet count (bleeding from gums/nose/mouth, bleeding that does not stop, unexpected bruising, reddish or pinkish urine); or blood clot in the blood vessels of the lungs (sudden breathlessness, cough with bloody sputum or intense chest pain).
Drug-Drug Interactions
Drug-Drug Interactions
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Taking thalidomide together with Prexx 500 mg Injection may increase the risk of blood clots and other complications.
How to manage the interaction:
Although taking thalidomide and Prexx 500 mg Injection together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
Combining Prexx 500 mg Injection with Clozapine can increase the risk of infection.
How to manage the interaction:
Co-administration of Prexx 500 mg Injection with Clozapine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
When Etanercept is used with Prexx 500 mg Injection, the likelihood or severity of infection may increase.
How to manage the interaction:
Although taking Prexx 500 mg Injection and Etanercept together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Taking Cladribine with Prexx 500 mg Injection can increase the risk of developing serious infections.
How to manage the interaction:
Although taking Cladribine and Prexx 500 mg Injection together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
When Prexx 500 mg Injection is taken with Infliximab, it can enhance the metabolism of Prexx 500 mg Injection. This can reduce the treatment outcome and can increase the risk or severity of developing serious infections.
How to manage the interaction:
Taking Prexx 500 mg Injection with Infliximab together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of Prexx 500 mg Injection with Baricitinib can increase the risk of developing serious infections.
How to manage the interaction:
Although taking Prexx 500 mg Injection and Baricitinib together can cause an interaction, it can be taken if your doctor has suggested it. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate. Do not stop using any medications without a doctor's advice.
Taking Tofacitinib with Prexx 500 mg Injection may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Prexx 500 mg Injection and Tofacitinib, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Co-administration of Meloxicam and Prexx 500 mg Injection together may increase the levels of Prexx 500 mg Injection in the blood.
How to manage the interaction:
Co-administration of Meloxicam with Prexx 500 mg Injection can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice symptoms like fever, chills, flu-like symptoms, mouth sores, severe diarrhea, or any injuries, call a doctor right away. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Eat a healthy diet and exercise regularly to maintain proper weight.
- Avoid smoking and alcohol consumption.
- Include vegetables and fruits in your diet.
- Avoid fast food, fried, processed food, refined carbs, and added sugar.
- Get optimal sleep; rest well.
- Drink enough water and eat fibre-rich foods, vegetables and fruits.
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Alcohol
Consult your doctor
It is not known if alcohol affects Prexx 500 mg Injection. Please consult your doctor.
Pregnancy
Unsafe
Pemetrexed belongs to pregnancy category D. The use of Prexx 500 mg Injection should be avoided during pregnancy as it might harm the unborn baby.
Breast Feeding
Unsafe
Breastfeeding must be discontinued during treatment with Prexx 500 mg Injection.
Driving
Caution
Prexx 500 mg Injection may cause tiredness. Caution is advised while driving or operating heavy machinery.
Liver
Consult your doctor
If you have a history of liver disease, inform your doctor before receiving Prexx 500 mg Injection.
Kidney
Caution
Dose adjustment may be needed. If you have a history of kidney disease, inform your doctor before receiving Prexx 500 mg Injection.
Children
Unsafe
Prexx 500 mg Injection is not recommended for children below 18 years as safety and effectiveness have not been established.
Heart
Please consult your doctor if you have any heart problems before taking Prexx 500 mg Injection.
Geriatrics
Consult your doctor
Please consult a doctor before administering Prexx 500 mg Injection to geriatric patients. Your doctor will prescribe Prexx 500 mg Injection if the benefits outweigh the risks.
FAQs
Prexx 500 mg Injection is used to treat Non-small cell lung cancer and malignant pleural mesothelioma.
Prexx 500 mg Injection works by blocking the action of substances that may help the cancer cells multiply.
Prexx 500 mg Injection may affect your ability to have children. Seek advice from the doctor about sperm storage before initiation of therapy. Use effective contraception and avoid fathering a child during treatment and for up to 3 months afterwards.
Prexx 500 mg Injection may suppress bone marrow suppression, resulting in cytopenia (low white blood cells, red blood cells, or platelets) and increased risk of infection. The doctor may adjust the dose based on the blood cell count and non-hematologic toxicity.
To lower the chances of side effects during anticancer treatment, your doctor may prescribe supplements like folic acid and vitamin B12 prior to and during treatment with Prexx 500 mg Injection.
No, Prexx 500 mg Injection is not a vesicant (irritant).
Prexx 500 mg Injection is safe when used as per the dose and duration advised by a doctor.
Yes, Prexx 500 mg Injection may cause hair loss as its side effect. If you have any concerns, contact your doctor.
Prexx 500 mg Injection causes side effects such as nausea, vomiting, loss of appetite, tiredness, pain/redness/swelling/ sores in the mouth, sore throat, skin rash, hair loss and low white blood cells. These side effects do not require medical attention and will gradually reduce over time. Please, contact a doctor if these persist or worsen.
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