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  3. Prolix 10 Injection 2 ml

Prolix 10 Injection 2 ml, Pack of 1 INJECTION
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Prolix 10 Injection 2 ml belongs to the class of loop diuretics. It is used in the treatment of Oedema (swelling) and hypertension (high blood pressure). This medicine contains furosemide, which works by reducing the excess fluid levels in the body and thus reduces swelling. Common side effects include frequent urination, feeling thirsty, dry mouth, headache, nausea or vomiting, headache, confusion and dizziness.
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Composition :

FUROSEMIDE-10MG

Manufacturer/Marketer :

Themis Pharmaceutical Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Prolix 10 Injection 2 ml

Prolix 10 Injection 2 ml belongs to a group of medicines called loop diuretics used to treat oedema. It may also be used in the treatment of extremely high blood pressure that may lead to life-threatening conditions (hypertensive crisis). Oedema, also known as fluid overload, occurs due to the build-up of fluid in spaces between the tissues leading to swelling. Hypertension or high blood pressure is a chronic condition in which the force exerted by the blood against the artery wall increases.

Prolix 10 Injection 2 ml contains Furosemide, which works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

Prolix 10 Injection 2 ml will be administered by a qualified healthcare professional. Kindly do not self-administer. In some cases, you may experience frequent urination (peeing more than normal), feeling thirsty, dry mouth, headache, feeling confused or dizzy, nausea or vomiting. Most of these side effects of Prolix 10 Injection 2 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Let your doctor know if you are allergic to any of the components in Prolix 10 Injection 2 ml. Inform your doctor if you are suffering from kidney, liver, or heart disease. Consult your doctor if you are pregnant or breastfeeding. Do not drive or operate machinery as Prolix 10 Injection 2 ml may cause dizziness. Prolix 10 Injection 2 ml is recommended for children and adolescents under the age of 15 only in exceptional cases. Avoid alcohol intake while on treatment with Prolix 10 Injection 2 ml as it may cause excessive lowering of blood pressure.

Uses of Prolix 10 Injection 2 ml

Treatment of Oedema (swelling), Hypertension (high blood pressure)

Directions for Use

Prolix 10 Injection 2 ml will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

Prolix 10 Injection 2 ml contains furosemide, a loop diuretic which increases the excretion of salt and water through urine by acting on a targeted or specific part of the kidney called the loop of Henle. Thereby decreasing fluid in the tissues, and aiding in treating swelling (oedema). It also helps reduce the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, treats high blood pressure, reducing the chances of heart attack or stroke.

How Prolix 10 Injection 2 ml Works

Prolix 10 Injection 2 ml contains Furosemide, which works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

Storage

Store in a cool and dry place away from sunlight
Side effects of Prolix 10 Injection 2 ml
  • Consume controlled amounts of salt to raise sodium levels.
  • Eat fresh fruits like apples, berries, oranges, mangoes, and bananas.
  • Include fresh vegetables like broccoli, sweet potatoes, beets, okra, spinach, peppers, carrots, and edamame.
  • Choose frozen vegetables without added butter or sauce.
  • Drink electrolyte beverages like sports drinks or electrolyte solutions to replenish sodium and other electrolytes.
  • Avoid excessive salt intake, but allow for controlled increases as needed.
  • Monitor and manage underlying health conditions that may contribute to hyponatremia.
  • Let your doctor know if you experience symptoms such as fatigue, weakness, muscle cramps, or respiratory depression. Hyperchloremia may cause these.
  • Hyperchloremia is a condition in which the blood has an excessive level of chloride ions, which can disrupt the body's acid-base balance and lead to various complications.
  • Your doctor will thoroughly evaluate to determine if your medication is causing the hyperchloremia.
  • If your medication is found to be the cause, your doctor may adjust your medication regimen or switch you to alternative medicines.
  • To manage hyperchloremia, focus on consuming a balanced diet that is low in chloride-rich foods. Include potassium-rich foods like bananas, leafy greens, and sweet potatoes to help balance electrolyte levels.
  • Adopting a healthy lifestyle can help manage your condition. Aim for regular physical activity, stress-reducing techniques, and adequate sleep to help your body recover.
  • Regular monitoring and follow-ups with your doctor are crucial to managing your condition. Schedule check-ups as recommended by your doctor to monitor your symptoms and adjust your treatment plan as needed.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Drink plenty of water to eliminate uric acid.
  • Avoid purine-rich foods such as red meat, organ meats, certain seafood (sardines, anchovies) and too much alcohol.
  • Regularly do low impact exercises like swimming or walking.
  • To reduce pain and swelling, apply ice packs to the affected area.
  • Take rest and avoid activities that strain the affected joint.
  • Elevate the affected joint to encourage fluid drainage.
  • Aim for weight loss and maintain a healthy body weight to reduce the risk of gout.

What if I have taken an overdose of Prolix 10 Injection 2 ml

Prolix 10 Injection 2 ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include extreme thirst, dry mouth, dizziness, confusion, extreme tiredness, vomiting, and stomach cramps. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

Inform your doctor if you have/had low blood pressure (hypotension), liver disease, diabetes, any difficulty peeing, Addison's disease (a rare disorder of the adrenal glands), gout, dehydration (being thirsty, having a dry mouth), and electrolyte imbalance. Consult your doctor if you are pregnant or planning for pregnancy; your doctor will weigh the benefits and potential risks before prescribing Prolix 10 Injection 2 ml. Do not drive or operate machinery as Prolix 10 Injection 2 ml may cause dizziness. Avoid alcohol intake while on treatment with Prolix 10 Injection 2 ml as it may cause excessive lowering of blood pressure.

Drug-Drug Interactions

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FurosemideZiprasidone
Critical
FurosemideAmikacin
Severe

Drug-Drug Interactions

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FurosemideZiprasidone
Critical
How does the drug interact with Prolix 10 Injection 2 ml:
Taking Ziprasidone with Prolix 10 Injection 2 ml can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Prolix 10 Injection 2 ml is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, dizziness, nausea, or vomiting. Do not discontinue any medications without consulting a doctor.
FurosemideAmikacin
Severe
How does the drug interact with Prolix 10 Injection 2 ml:
Coadministration of Amikacin with Prolix 10 Injection 2 ml can increase the risk of developing kidney disorder and other side effects.

How to manage the interaction:
Although taking amikacin and Prolix 10 Injection 2 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience ringing in the ears, irregular urination, muscle cramps, vomiting, or weakness, consult the doctor. Do not discontinue any medications without a doctor's advice.
FurosemideTizanidine
Severe
How does the drug interact with Prolix 10 Injection 2 ml:
Combining Tizanidine and Prolix 10 Injection 2 ml can lower your blood pressure.

How to manage the interaction:
Taking Tizanidine and Prolix 10 Injection 2 ml together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like headache, dizziness, lightheadedness, fainting, and changes in pulse or heart rate, contact your doctor immediately. Avoid driving or operating hazardous machinery until you know how the medications affect you, use caution when getting up from a sitting or lying position, and do not discontinue any medications without consulting your doctor.
FurosemideTobramycin
Severe
How does the drug interact with Prolix 10 Injection 2 ml:
Taking Prolix 10 Injection 2 ml with Tobramycin can increase the risk of hearing loss and kidney problems.

How to manage the interaction:
Although there is a possible interaction between Tobramycin and Prolix 10 Injection 2 ml, you can take these medicines together if prescribed by your doctor. Do not discontinue any medications without consulting your doctor.
FurosemideDiclofenac
Severe
How does the drug interact with Prolix 10 Injection 2 ml:
Concomitant administration of diclofenac and Prolix 10 Injection 2 ml may decrease the therapeutic efficacy of Prolix 10 Injection 2 ml and adversely affect renal function.

How to manage the interaction:
There may be a possible interaction between diclofenac and Prolix 10 Injection 2 ml, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms like nausea, dizziness, irregular heartbeats, altered blood pressure, tingling. Do not stop using any medications without first talking to your doctor.
FurosemideStreptomycin
Severe
How does the drug interact with Prolix 10 Injection 2 ml:
Coadministration of Streptomycin and Prolix 10 Injection 2 ml may increase the risk or severity of hearing or kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Streptomycin and Prolix 10 Injection 2 ml, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, hearing difficulty, swelling, body aches, increased or decreased urination, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
FurosemideGlimepiride
Severe
How does the drug interact with Prolix 10 Injection 2 ml:
Co-administration of Prolix 10 Injection 2 ml may interfere with blood glucose control and lower the effectiveness of Glimepiride.

How to manage the interaction:
Although there is a possible interaction, glimepiride can be taken with Prolix 10 Injection 2 ml if prescribed by the doctor. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
FurosemideTirzepatide
Moderate
How does the drug interact with Prolix 10 Injection 2 ml:
Prolix 10 Injection 2 ml may decrease the effectiveness of tirzepatide thereby causing the increase in blood glucose levels.

How to manage the interaction:
Close blood glucose monitoring is recommended when on treatment with Prolix 10 Injection 2 ml.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.
  • Eat natural diuretic foods such as Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, pumpkin, and garlic.
  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.
  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
  • Reduce or eliminate trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
  • Avoid consumption of too much salt or salty food.
  • Regular physical activity or exercise like walking improves the blood flow.
  • Whenever possible, elevate your legs or the swollen area on a chair or pillows.
  • Avoid standing or sitting for extended periods of time.
  • Avoid chronic stress as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Habit Forming

No

Therapeutic Class

DIURETIC

Prolix 10 Injection 2 ml Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid alcohol intake while on treatment with Prolix 10 Injection 2 ml as it may cause excessive lowering of blood pressure.

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Pregnancy

Caution

Prolix 10 Injection 2 ml should not be used during pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Prolix 10 Injection 2 ml.

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Breast Feeding

Unsafe

Prolix 10 Injection 2 ml passes into breast milk and may inhibit the secretion of milk. Therefore it is not recommended for breastfeeding women.

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Driving

Caution

Prolix 10 Injection 2 ml may cause dizziness; thus, avoid driving or using machinery unless you are alert.

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Liver

Caution

Notify your doctor if you have a history of liver diseases/conditions. Your doctor may adjust your dose accordingly.

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Kidney

Caution

Notify your doctor if you have a history of kidney diseases/conditions. Your doctor may adjust your dose accordingly.

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Children

Caution

Please consult your doctor. Prolix 10 Injection 2 ml is recommended for adolescents and children under the age of 15 only in exceptional cases.

Have a query?

FAQs

Prolix 10 Injection 2 ml belongs to a group of medicines called loop diuretics used to treat oedema. It may also be used in the treatment of extremely high blood pressure that may lead to life-threatening conditions (hypertensive crisis).

Prolix 10 Injection 2 ml increases urine production to eliminate excess water (fluid retention) in the body. This reduces the fluid in the tissues, which helps in reducing swelling (oedema).

Parenteral therapy should only be used for patients unable to take oral medications or in an emergency clinical situation. Prolix 10 Injection 2 ml is prescribed by the doctor when rapid and effective removal of excess fluid is required, for patients who cannot take it orally, in an emergency or during periods of extremely high blood pressure, which may result in life-threatening conditions.

Prolix 10 Injection 2 ml is contraindicated in people with anuria (reduction or absence of urine) or a history of hypersensitivity to Furosemide.

Prolix 10 Injection 2 ml may cause weight loss as your body loses water. However, do not use Prolix 10 Injection 2 ml to lose weight. If you have any concerns regarding weight, consult your doctor.

Notify your doctor if you are taking lithium because Prolix 10 Injection 2 ml decreases lithium renal clearance and increases the risk of lithium toxicity.

Country of origin

INDIA

Manufacturer/Marketer address

69-B , J-Type Area ,G.I.D.C. Industrial Estate,Near Cng Gas Station,Vapi- 396195.
Other Info - PRO2064

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jan 1, 2025 | 2:45 PM IST

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Reference

  1. https://www.hpra.ie/img/uploaded/swedocuments/dbdd819c-dc74-435c-b674-c07e490bfb4d.pdf
  2. https://www.nhs.uk/medicines/furosemide/
  3. https://pubmed.ncbi.nlm.nih.gov/2185908/
  4. https://www.medicines.org.uk/emc/files/pil.7371.pdf
  5. https://www.drugs.com/drug-interactions/furosemide-index.html?filter=3
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