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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Prostagard-D 8 Capsule is used to treat the symptoms of benign prostatic hyperplasia (BPH) in adults with an enlarged prostate gland. It helps to relieve symptoms such as difficulty urinating or urge to urinate more often and improve your ability to urinate. It contains Silodosin and Dutasteride, which relaxes smooth muscles in the bladder and prostate and shrink of the size of the prostate gland. It reduces the BPH symptoms and improves your ability to urinate. In some cases, you may experience certain common side effects such as dizziness, headache, nasal congestion (stuffy nose), and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Aristo Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Prostagard-D 8 Capsule

Prostagard-D 8 Capsule is used to treat benign prostatic hyperplasia (BPH) in adults. The prostate is a small, muscular gland in the male reproductive system. Benign prostatic hyperplasia is a common condition that occurs when the cells of the prostate gland begin to multiply.

Prostagard-D 8 Capsule is a combination of Silodosin and Dutasteride. This medicine works by blocking the action of alpha-1 receptors, causing smooth muscle relaxation in the bladder and prostate. Dutasteride blocks the action of a 5-alpha reductase enzyme, resulting in a shrinkage of the size of the prostate gland.

In some cases, you may experience certain common side effects such as dizziness, headache, nasal congestion (stuffy nose), and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, talk to your doctor if you experience these side effects persistently.

Take Prostagard-D 8 Capsule as advised. Your physician will decide the dosage based on your medical condition. You can take Prostagard-D 8 Capsule with or without food. It is advised not to take more than the recommended dose of Prostagard-D 8 Capsule . Do not chew, crush, or break the medicine. It is crucial to have your lipid profile checked regularly.

Inform your physician if you are allergic to Prostagard-D 8 Capsule . Avoid consumption of alcohol as it may increase the side effects like dizziness and low blood pressure. If you take Prostagard-D 8 Capsule with any antihypertensive medicine, your blood pressure could suddenly drop to a life-threatening level. So, avoid intake of Prostagard-D 8 Capsule with antihypertensive drugs. Prostagard-D 8 Capsule is not recommended for use in female population and children.

Uses of Prostagard-D 8 Capsule

Prostagard-D 8 Capsule is used in the treatment of Benign Prostatic Hyperplasia (BPH) in men. The detailed uses of Prostagard-D 8 Capsule are as follows:

  • Treatment of Benign Prostatic Hyperplasia (BPH): Prostagard-D 8 Capsule helps reduce prostate size by blocking the production of hormones responsible for its growth and also improves urinary flow and reduces symptoms like difficulty urinating, frequent urges, and weak urine stream.
  • Relaxation of Bladder and Prostate Muscles: Prostagard-D 8 Capsule works by relaxing the muscles in the bladder and prostate, making urination easier and helping relieve urinary discomfort associated with an enlarged prostate.
  • Prevention of Urinary Blockage: Prostagard-D 8 Capsule reduces the risk of complete urinary obstruction, which can occur if BPH is left untreated and helps maintain normal urinary function over time.

Directions for Use

  • Prostagard-D 8 Capsule can be taken with or without food, as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Prostagard-D 8 Capsule as a whole with a glass of water.
  • Do not crush, chew, or open it.

Medicinal Benefits

  • Prostagard-D 8 Capsule is a combination of Silodosin and Dutasteride used to treat the symptoms of benign prostatic hyperplasia (BPH) in adults with an enlarged prostate gland.
  • Prostagard-D 8 Capsule causes smooth muscle relaxation in the bladder and prostate, and also causes a shrinkage of the size of the prostate gland.
  • It helps to relieve symptoms such as difficulty urinating or the urge to urinate more often and improve your ability to urinate. 

How Prostagard-D 8 Capsule Works

Prostagard-D 8 Capsule is a combination of two drugs, namely; Silodosin and Dutasteride. Silodosin works by blocking the action of alpha-1 receptors, causing smooth muscle relaxation in the bladder and prostate. Dutasteride works by blocking the action of a 5-alpha reductase enzyme, resulting in a shrink of the size of the prostate gland. Prostagard-D 8 Capsule reduces the BPH symptoms and improves your ability to urinate.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Prostagard-D 8 Capsule
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • A blocked nose can be relieved by drinking more water, which helps clear fluids.
  • Use saline nasal spray available over the counter to relieve blockage or blow harder to remove the mucus.
  • Use nasal strips that can be placed on the nose to widen nostrils and increase airflow.
  • Keep a humidifier around to moisten air at home/workplace.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.
  • To help reduce symptoms, eat foods high in vitamin C, such as oranges, bell peppers and strawberries.
  • Lightly blow your nose to remove mucus; steer clear of blowing hard.
  • Infections can be prevented from spreading by washing hands frequently and staying away from other people.
  • If you have allergies, do your best to avoid triggering allergens that could contribute to a runny nose.
  • Don't smoke, as irritating the nasal passages can make a runny nose worse.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Prostagard-D 8 Capsule

Do not take more than the prescribed dose of Prostagard-D 8 Capsule as it may cause overdose. Symptoms of overdose include dizziness, drowsiness, fainting, or severe decrease in blood pressure. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Prostagard-D 8 Capsule if you are allergic to Prostagard-D 8 Capsule or any other components present in it. To treat your condition effectively, continue taking Prostagard-D 8 Capsule for as long as your doctor has prescribed it. Try not to stop taking it on your own.
  • If you take Prostagard-D 8 Capsule with any antihypertensive medicine, your blood pressure could suddenly drop to a life-threatening level. So, avoid intake of Prostagard-D 8 Capsule with antihypertensive drugs.
  • Inform your doctor if you have/had a heart attack or stroke or heart failure, low blood pressure, kidney or liver disease, have certain eye diseases, loss of vision due to loss of blood flow to the optic (eye) nerve before taking Prostagard-D 8 Capsule .
  • You are advised not to drive or operate heavy machinery after taking Prostagard-D 8 Capsule as it may cause dizziness.
  • Avoid consuming alcohol along with Prostagard-D 8 Capsule as it could lead to increased dizziness and drowsiness.
  • Older patients may be more sensitive to the side effects of Prostagard-D 8 Capsule , especially dizziness and low blood pressure when getting up from a sitting or lying position. 
  • Prostagard-D 8 Capsule is intended for male patients only. Therefore, it should not be administered to women and children under 18 years of age.

Drug-Drug Interactions

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SilodosinTelithromycin
Critical
SilodosinTelaprevir
Critical

Drug-Drug Interactions

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SilodosinTelithromycin
Critical
How does the drug interact with Prostagard-D 8 Capsule:
Co-administration of Telithromycin and Prostagard-D 8 Capsule together can increase the effect of Prostagard-D 8 Capsule which may lead to side effects like extremely low blood pressure and increased heart rate.

How to manage the interaction:
Taking Telithromycin and Prostagard-D 8 Capsule together is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs like dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation, call a doctor right away. Do not stop using any medications without a doctor's advice.
SilodosinTelaprevir
Critical
How does the drug interact with Prostagard-D 8 Capsule:
Co-administration of Telaprevir and Prostagard-D 8 Capsule together can increase the effect of Prostagard-D 8 Capsule which may lead to side effects like extremely low blood pressure and increased heart rate.

How to manage the interaction:
Taking Telaprevir and Prostagard-D 8 Capsule together is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation-call a doctor right away. Do not stop using any medications without a doctor's advice.
SilodosinBoceprevir
Critical
How does the drug interact with Prostagard-D 8 Capsule:
Co-administration of Boceprevir and Prostagard-D 8 Capsule together can increase the effect of Prostagard-D 8 Capsule which may lead to side effects including extremely low blood pressure, increased heart rate.

How to manage the interaction:
Taking Boceprevir and Prostagard-D 8 Capsule together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Prostagard-D 8 Capsule:
Coadministration of Prostagard-D 8 Capsule with Ritonavir can significantly increase the blood levels and effects of Prostagard-D 8 Capsule, and this may cause low blood pressure and increase heart rate, especially when you rise from a sitting or lying position.

How to manage the interaction:
Taking Ritonavir and Prostagard-D 8 Capsule together is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation-call a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Prostagard-D 8 Capsule:
Coadministration of Prostagard-D 8 Capsule and posaconazole may significantly increase the blood levels and effects of Prostagard-D 8 Capsule.

How to manage the interaction:
Although there is an interaction between Posaconazole and Prostagard-D 8 Capsule, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, nasal congestion, and headache. Do not discontinue any medications without consulting a doctor.
SilodosinCobicistat
Critical
How does the drug interact with Prostagard-D 8 Capsule:
Co-administration of Cobicistat and Prostagard-D 8 Capsule together can increase the effect of Prostagard-D 8 Capsule which may lead to side effects including extremely low blood pressure, increased heart rate.

How to manage the interaction:
Taking Cobicistat with Prostagard-D 8 Capsule together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Prostagard-D 8 Capsule:
Co-administration of Atazanavir and Prostagard-D 8 Capsule together can increase the effectiveness of Prostagard-D 8 Capsule which may lead to side effects including extremely low blood pressure, increased heart rate.

How to manage the interaction:
Taking Atazanavir and Prostagard-D 8 Capsule together is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Prostagard-D 8 Capsule:
Coadministration of Prostagard-D 8 Capsule with Ketoconazole may lead to side effects including extremely low blood pressure, and increased heart rate.

How to manage the interaction:
Taking Ketoconazole with Prostagard-D 8 Capsule together is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation. Do not discontinue any medications without consulting a doctor.
SilodosinNefazodone
Critical
How does the drug interact with Prostagard-D 8 Capsule:
Co-administration of Nefazodone and Prostagard-D 8 Capsule together can increase the effect of Prostagard-D 8 Capsule which may lead to side effects including extremely low blood pressure, increased heart rate.

How to manage the interaction:
Taking Nefazodone with Prostagard-D 8 Capsule together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.
SilodosinConivaptan
Critical
How does the drug interact with Prostagard-D 8 Capsule:
When Prostagard-D 8 Capsule and Conivaptan are taken together, may significantly increase the blood levels and effects of Prostagard-D 8 Capsule, this may cause blood pressure to fall excessively and heart rate to increase, especially when you rise from a sitting or lying position.

How to manage the interaction:
Taking Prostagard-D 8 Capsule with Conivaptan together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintaining a healthy weight, eating a balanced diet, and regular exercising may help your bladder empty at a normal rate.
  • Avoid consumption of alcohol to treat your condition effectively as consuming an excessive amount of alcohol may make you pee more and can irritate your bladder.
  • Limit the amount of fluids and caffeine you drink, especially before you go out or go to bed.
  • Stay warm, cold can make it feel more urgent to pee.
  • Avoid usage of tobacco.
  • Do daily exercise to strengthen your pelvic floor muscles.

Habit Forming

No

Therapeutic Class

GENITOURINARY TRACT AGENTS
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Alcohol

Unsafe

You are advised not to consume alcohol while taking Prostagard-D 8 Capsule as it makes you pee more and can irritate your bladder and also increased dizziness and lower blood pressure.

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Pregnancy

Not applicable

Women should not use Prostagard-D 8 Capsule as it is used to treat benign prostatic hyperplasia (BPH) in men only.

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Breast Feeding

Not applicable

Women should not use Prostagard-D 8 Capsule as it is used to treat benign prostatic hyperplasia (BPH) in men only.

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Driving

Unsafe

Prostagard-D 8 Capsule may cause dizziness. Therefore you are advised to drive and operate machinery only if you are alert.

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Liver

Caution

Prostagard-D 8 Capsule should be used with caution in patients with liver disease. The dose adjustment may be needed in such patients.

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Kidney

Caution

Prostagard-D 8 Capsule should be used with caution in patients with kidney disease. The dose adjustment may be needed in such patients.

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Children

Unsafe

Prostagard-D 8 Capsule is not recommended for children below 18 years of age as the safety and efficacy are not established.

Have a query?

FAQs

Prostagard-D 8 Capsule is used to treat the symptoms of Benign Prostatic Hyperplasia (BPH) in men.

No, Prostagard-D 8 Capsule should not be taken along with blood-pressure-lowering medicines. Prostagard-D 8 Capsule may cause a sudden drop in your blood pressure which could lead to dizziness or fainting. Therefore, if Prostagard-D 8 Capsule is taken along with blood pressure lowering medicines, it could lead to a severe decrease in blood pressure which could be lethal.

Yes, Prostagard-D 8 Capsule may cause dizziness. You are advised not to drive or operate heavy machinery after taking Prostagard-D 8 Capsule as it may cause dizziness. Drive or operate machinery only if you are alert.

No, Prostagard-D 8 Capsule should not be taken by women. It is intended to treat symptoms of benign prostatic hyperplasia (BPH) in adult men only.

No, you are advised not to consume alcohol while taking Prostagard-D 8 Capsule as it makes you pee more and can irritate your bladder and also increase dizziness and lower blood pressure. Therefore, you are advised not to consume excessive amounts of alcohol while taking Prostagard-D 8 Capsule .

Prostagard-D 8 Capsule is a combination of two drugs, namely; Silodosin and Dutasteride used to treat the symptoms of benign prostatic hyperplasia (BPH) in adults with an enlarged prostate gland. Silodosin belongs to a class of alpha-1 receptors (located in prostate and bladder) blocker that works by blocking the action of alpha-1 receptors and causes smooth muscle relaxation in the bladder and prostate. Dutasteride belongs to a class of 5-alpha reductase that works by blocking the action of a 5-alpha reductase enzyme, resulting in a shrink of the size of the prostate gland. Prostagard-D 8 Capsule reduces the BPH symptoms and improves your ability to urinate.

The side effects of Prostagard-D 8 Capsule include dizziness, headache, diarrhoea, nasal congestion (stuffy nose), impotence (erectile dysfunction) and ejaculation disorder. If these side effects persist or worsen, please consult your doctor.

You should take Prostagard-D 8 Capsule for as long as it is prescribed by your doctor. It is usually advised for long term use. If you discontinue Prostagard-D 8 Capsule in the midway, it may worsen your condition.

Take Prostagard-D 8 Capsule as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it. Take it at the same time every day. Do not miss doses or stop the treatment before the prescribed duration, even if you feel well.

Prostagard-D 8 Capsule is effective if used in the dose and duration prescribed by your doctor. Even if you see improvement in your condition, do not stop using Prostagard-D 8 Capsule too early as the symptoms may return or worsen.

Benign prostatic hyperplasia (BPH) also known as prostate gland enlargement is a common condition in older men. The symptoms include urgent or frequent need to urinate, inability to completely empty the bladder and increased frequency of urination at night (nocturia).

The use of Prostagard-D 8 Capsule is contraindicated in patients who are allergic to any ingredients of it. Prostagard-D 8 Capsule should be used with caution in patients with underlying liver or kidney disease. If you have any concerns, consult your doctor.

Store Prostagard-D 8 Capsule in a cool, dry and dark place. Keep it out of reach of children.

Prostagard-D 8 Capsule is safe if used in the dose and duration prescribed by your doctor. Take it exactly as advised and do not miss any dose. Follow your doctor's instructions carefully and if any of the side effects bother you, inform your doctor.

It is best to take Prostagard-D 8 Capsule after meals. Swallow it as whole with water. Do not open, chew or crush it. Follow your doctor’s instructions carefully.

Country of origin

India

Manufacturer/Marketer address

Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.
Other Info - PRO1974

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