Protussa Cough Syrup | Uses, Side Effects, Price

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Composition:CHLORPHENIRAMINE-1MG+DEXTROMETHORPHAN-5MG

Prescription Medicine

Protussa Cough Syrup is used to treat dry cough. It reduces throat irritation, runny nose, watery eyes, coughing, and sneezing. This combination is particularly helpful in treating allergic respiratory disorders and dry, irritating coughs, as well as boosting comfort and sleep quality.

Written By Veda Maddala , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

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More about the Product

Composition :

CHLORPHENIRAMINE-1MG+DEXTROMETHORPHAN-5MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Protussa Cough Syrup

Protussa Cough Syrup is used to treat dry cough. Coughing is the body’s way of clearing irritants (such as allergens, mucus, or smoke) from the airways. A dry cough is tickly and doesn't produce any viscous or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways.

Protussa Cough Syrup is a combination of chlorpheniramine and dextromethorphan. Chlorpheniramine works by blocking the action of histamine, a substance involved in allergic reactions. Dextromethorphan blocks the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough.

Some people may experience dry mouth, throat, or nose; drowsiness; blurred vision; constipation; dizziness; or restlessness or excitation. Most of the side effects do not require medical attention. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Protussa Cough Syrup or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Protussa Cough Syrup. Avoid using Protussa Cough Syrup if you have taken medications such as linezolid, phenelzine, selegiline, or Isocarboxazid in the past 14 days.

Uses of Protussa Cough Syrup

Protussa Cough Syrup is used to relieve dry cough and allergy-related symptoms. The detailed uses of Protussa Cough Syrup are as follows:

Dry cough: Protussa Cough Syrup treats persistent non-productive cough by calming the cough reflex.
Allergy symptoms: Protussa Cough Syrup reduces sneezing, runny nose, and watery eyes due to allergic reactions.

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Directions for Use

Protussa Cough Syrup can be taken with or without food. However, taking it with food or milk may help reduce stomach upset.
It is recommended to take Protussa Cough Syrup every 4-6 hours or as advised by your doctor.
Shake the bottle well before each use.
Take the prescribed dose by mouth using the measuring cup provided with the pack.
Avoid using regular household spoons, as they may not measure the dose correctly.

Key Benefits

Dry cough relief: Helps lessen a persistent, bothersome cough by suppressing the cough reflex.
Reduces allergy symptoms: Reduces runny nose, watery eyes, sneezing, and allergy-related itching.
Flu and cold relief: Helps control common cold symptoms and improve overall comfort.
Reduces throat irritation: Alleviates cough-related dryness and throat discomfort.
Enhances sleep: It helps people sleep better at night by reducing allergy symptoms and coughing.
Reduces allergy-related nasal congestion: Antihistamines help reduce nasal secretions.
Promotes respiratory comfort: During upper respiratory infections, this helps patients breathe more easily.

How Protussa Cough Syrup Works

Protussa Cough Syrup is a combination of two drugs: chlorpheniramine (antihistamine) and dextromethorphan (cough suppressant). • Chlorpheniramine belongs to the class of antihistamines or anti-allergic that work by blocking the action of histamine, a substance responsible for causing allergic reactions. • It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. • Dextromethorphan belongs to the class of cough suppressants that work by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough.

Storage

Store in a cool and dry place away from sunlight

Side effects of Protussa Cough Syrup 60 ml

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Drowsiness

Get enough sleep. Maintain a regular sleep cycle.
Eat a healthy diet and exercise regularly.
Manage stress with yoga or meditation.
Limit alcohol and caffeine.
Avoid driving or operating machinery unless you are alert.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Sedation

Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Confusion

Confusion is a major psychotic disorder that needs immediate medical attention.
Acknowledge your experience and put effort to control confusion.
Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
Talk to your dietician and consume food that can improve your mental health.

What if I have taken an overdose of Protussa Cough Syrup

Do not take more than the prescribed dose of Protussa Cough Syrup as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

If you are allergic to Protussa Cough Syrup or any other medicines, please tell your doctor.
If you are pregnant or breastfeeding, it is advised to inform your doctor before using Protussa Cough Syrup.
Protussa Cough Syrup is not recommended for children below 2 years of age.
If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Protussa Cough Syrup.
Avoid using Protussa Cough Syrup if you have taken medications such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine, or methylene blue injection in the past 14 days.
Drink plenty of fluids while taking Protussa Cough Syrup to loosen mucus.

Drug-Drug Interactions

DextromethorphanRasagiline

Critical

DextromethorphanTranylcypromine

Critical

Drug-Drug Interactions

DextromethorphanRasagiline

Critical

How does the drug interact with Protussa Cough Syrup 60 ml:
Taking Rasagiline with Protussa Cough Syrup 60 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Protussa Cough Syrup 60 ml with Rasagiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.

DextromethorphanTranylcypromine

Critical

How does the drug interact with Protussa Cough Syrup 60 ml:
Taking Tranylcypromine with Protussa Cough Syrup 60 ml can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Protussa Cough Syrup 60 ml with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fit blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.

DextromethorphanProcarbazine

Critical

How does the drug interact with Protussa Cough Syrup 60 ml:
Co-administration of Protussa Cough Syrup 60 ml and Procarbazine may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Procarbazine with Protussa Cough Syrup 60 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.

DextromethorphanSelegiline

Critical

How does the drug interact with Protussa Cough Syrup 60 ml:
Co-administration of Protussa Cough Syrup 60 ml and Selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Selegiline with Protussa Cough Syrup 60 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.

DextromethorphanIsocarboxazid

Critical

How does the drug interact with Protussa Cough Syrup 60 ml:
Co-administration of Isocarboxazid with Protussa Cough Syrup 60 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Protussa Cough Syrup 60 ml and Isocarboxazid can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

DextromethorphanPhenelzine

Critical

How does the drug interact with Protussa Cough Syrup 60 ml:
Co-administration of Phenelzine and Protussa Cough Syrup 60 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Phenelzine and Protussa Cough Syrup 60 ml can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

DextromethorphanPargyline

Critical

How does the drug interact with Protussa Cough Syrup 60 ml:
Co-administration of Pargyline and Protussa Cough Syrup 60 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Protussa Cough Syrup 60 ml and Pargyline can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

ChlorpheniraminePotassium citrate

Critical

How does the drug interact with Protussa Cough Syrup 60 ml:
Taking Protussa Cough Syrup 60 ml and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Protussa Cough Syrup 60 ml with Potassium citrate is not recommended as it can lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.

ChlorpheniraminePotassium chloride

Critical

How does the drug interact with Protussa Cough Syrup 60 ml:
Taking Protussa Cough Syrup 60 ml and Potassium chloride (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Protussa Cough Syrup 60 ml with Potassium chloride it not recommended as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor. Do not discontinue any medications without a doctor's advice.

DextromethorphanFluvoxamine

Severe

How does the drug interact with Protussa Cough Syrup 60 ml:
Co-administration of Protussa Cough Syrup 60 ml and Fluvoxamine may increase the risk serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a possible interaction between Protussa Cough Syrup 60 ml and Fluvoxamine, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as seizures (fits), confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, tremors, incoordination, blurred vision, muscle spasm or stiffness, nausea, vomiting, stomach cramps, and diarrhea, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Diet & Lifestyle Advise

Diet:

To ease the throat and reduce coughing, drink lots of warm liquids, such as water, soups, and herbal teas.
Avoid alcohol, as it may intensify the drowsiness that the medication causes.
Eat balanced, light meals to avoid unsettled stomachs.
Avoid spicy or extremely cold foods if they aggravate your cough or sore throat.

Lifestyle changes:

To aid the body's faster recovery, obtain sufficient sleep and rest.
Avoid dust, smoke, and other irritants that can exacerbate allergy or cough symptoms.
To stop infections and the spread of disease, practice excellent hygiene, such as washing your hands frequently.

Stress management:

To reduce stress and facilitate healing, engage in relaxation techniques such as deep breathing or meditation.
To elevate your mood and lessen tension, engage in simple activities like taking a leisurely stroll or listening to relaxing music.

Environmental changes:

Keep your environment free of smoke, dust, and strong odours that could aggravate your allergies or cough.
If the air is dry, use a humidifier to assist in relieving sore throats and lessen coughing.

Habit Forming

Therapeutic Class

[COUGH AND COLD PREPARATIONS ]

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Alcohol

Unsafe

Avoid consumption of alcohol with Protussa Cough Syrup as it may increase drowsiness. Please consult a doctor before consuming alcohol with Protussa Cough Syrup.

Pregnancy

Consult your doctor

The safety of Protussa Cough Syrup in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks benefits outweigh risks.

Breast Feeding

Consult your doctor

It is unknown whether Protussa Cough Syrup is excreted in human milk. Protussa Cough Syrup is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

Driving

Caution

Protussa Cough Syrup may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Protussa Cough Syrup.

Liver

Caution

Take Protussa Cough Syrup with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

Kidney

Consult your doctor

If you have any concerns regarding the use of Protussa Cough Syrup in patients with kidney problems, please consult a doctor.

Children

Consult your doctor

Protussa Cough Syrup is not recommended for children below 2 years of age. However, please consult a doctor before using Protussa Cough Syrup in children.

Heart

Caution

Protussa Cough Syrup should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Protussa Cough Syrup.

Geriatrics

Unsafe

Protussa Cough Syrup is not recommended for use in elderly patients as it can lead to side effects like confusion, dizziness, difficulty concentration, etc.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India

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Author Details

Written By

Veda Maddala

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Feb 24, 2026 | 9:27 AM IST

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Protussa Cough Syrup 60 ml