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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Proxym-MR Tablet is used to treat osteoarthritis, rheumatoid arthritis, pain, and muscle spasms. It helps reduce mild to moderate pain and inflammation in the affected area. It also relaxes tight muscles, improves mobility, and relieves pain associated with muscle spasms.

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Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Proxym-MR Tablet

Proxym-MR Tablet is used to treat osteoarthritis, rheumatoid arthritis, pain, and muscle spasms. Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering (cartilage). Rheumatoid arthritis is an immune-related condition that causes joint pain and damage.

Proxym-MR Tablet contains Etodolac and Thiocolchicoside, which help reduce pain and relax tight muscles. It lowers swelling and discomfort in the affected area. It makes stiff muscles feel looser and improves movement. Together, Proxym-MR Tablet helps relieve pain caused by muscle spasms and injury.

Take Proxym-MR Tablet as prescribed by your doctor. Proxym-MR Tablet may cause common side effects such as nausea, vomiting, heartburn, stomach pain, and indigestion. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Proxym-MR Tablet is not recommended for children as safety and efficacy have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Proxym-MR Tablet

Proxym-MR Tablet is used in the treatment of Osteoarthritis, rheumatoid arthritis, pain, and muscle spasms. The detailed uses of Proxym-MR Tablet are as follows:

  • Osteoarthritis & Rheumatoid Arthritis: Proxym-MR Tablet reduces joint pain, inflammation, and stiffness.
  • Muscle Spasm-Related Pain: Proxym-MR Tablet is especially effective for back pain, neck pain, and post-traumatic muscle tension.
  • Ankylosing Spondylitis: Proxym-MR Tablet helps manage chronic inflammation and mobility issues in the spine.

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Directions for Use

  • Take Proxym-MR Tablet with food to reduce stomach upset.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Proxym-MR Tablet , when used as prescribed, may provide the following benefits:

For Osteoarthritis and Rheumatoid Arthritis:

  • It helps reduce joint pain, swelling, and stiffness.
  • Improves joint flexibility and ease of movement.
  • Supports better comfort during daily activities

For Pain:

  • Helps relieve moderate pain caused by injury or strain.
  • Reduces body aches and movement-related discomfort.
  • Improves overall physical comfort.

For Muscle Spasms:

  • Helps relax tight muscles and reduce painful spasms.
  • Decreases muscle stiffness and tension.
  • Improves muscle movement and flexibility.

How Proxym-MR Tablet Works

Proxym-MR Tablet contains Etodolac and Thiocolchicoside, which help relieve pain and relax tight muscles.• Etodolac blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme. By blocking the effect of COX enzymes. This helps reduce mild to moderate pain and inflammation at the injured or damaged site.• Thiocolchicoside works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improve muscle movements, thereby helping relieve pain due to muscle spasms.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

What if I have taken an overdose of Proxym-MR Tablet

Do not take more than the prescribed dose of Proxym-MR Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Proxym-MR Tablet if you are allergic to any of its contents.
  • Inform your doctor before taking Proxym-MR Tablet if you have stomach ulcers, bleeding problems, clotting problems, inflammatory bowel disease, severe heart, liver or kidney problems, galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption.
  • Consult your doctor if you are pregnant or breastfeeding.
  • Proxym-MR Tablet may cause drowsiness and dizziness, so drive only if you are alert.
  • Proxym-MR Tablet is not recommended for children as safety has not been established.
  • Stop taking Proxym-MR Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools.
  • Do not take any other NSAIDs for pain relief along with Proxym-MR Tablet unless prescribed.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Proxym-MR Tablet:
Using ketorolac together with Proxym-MR Tablet may increase the risk of side effects in the gastrointestinal tract (inflammation, bleeding and ulceration).

How to manage the interaction:
Taking Proxym-MR Tablet with Ketorolac is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Proxym-MR Tablet:
Co-administration of Proxym-MR Tablet with Meloxicam can raise the adverse consequences in the digestive system, including inflammation, bleeding, ulceration, and, in rare cases, perforation(rupture).

How to manage the interaction:
Taking Meloxicam with Proxym-MR Tablet is not recommended can result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Proxym-MR Tablet:
Everolimus can cause kidney problems, and taking it with Proxym-MR Tablet, can enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Proxym-MR Tablet and Everolimus, but it can be taken if prescribed by a doctor. However, consult a doctor if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm. Do not discontinue any medications without a doctor's advice.
EtodolacTinzaparin
Severe
How does the drug interact with Proxym-MR Tablet:
Use of tinzaparin with Proxym-MR Tablet may raise the risk of bleeding problems.

How to manage the interaction:
There may be a possibility of interaction between Proxym-MR Tablet and Tinzaparin, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness while taking these drugs, consult doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Proxym-MR Tablet:
Coadministration of Proxym-MR Tablet and Sirolimus can increase the risk or severity of kidney problems.

How to manage the interaction:
Although taking Sirolimus and Proxym-MR Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, consult a doctor if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Proxym-MR Tablet:
Co-administration of Proxym-MR Tablet with Prasugrel can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although taking Proxym-MR Tablet and Prasugrel together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
EtodolacPhenylbutazone
Severe
How does the drug interact with Proxym-MR Tablet:
Taking phenylbutazone with Proxym-MR Tablet may raise the risk of gastrointestinal adverse effects (inflammation, bleeding, ulceration, and, in rare cases, perforation).

How to manage the interaction:
Although taking Proxym-MR Tablet and Phenylbutazone together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, a severe headache, and/or weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
EtodolacPonatinib
Severe
How does the drug interact with Proxym-MR Tablet:
Taking Ponatinib with Proxym-MR Tablet may increase the risk of bleeding and severe hemorrhage.

How to manage the interaction:
Co-administration of Proxym-MR Tablet with Ponatinib can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, a severe headache, and/or weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Proxym-MR Tablet:
Use of Panobinostat with Proxym-MR Tablet may increase the risk of bleeding and severe hemorrhage.

How to manage the interaction:
Taking Proxym-MR Tablet with Panobinostat together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, a severe headache, and/or weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
EtodolacIomeprol
Severe
How does the drug interact with Proxym-MR Tablet:
Taking Proxym-MR Tablet and Iomeprol can increase the risk of kidney damage.

How to manage the interaction:
Taking Proxym-MR Tablet with Iomeprol together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor immediately. Drink lots of fluid after the procedure to stay hydrated and to flush the contrast agent out of your kidneys. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Physical Activity:

  • Do gentle activities like walking or swimming for 20–30 minutes to reduce joint stiffness.
  • Practice yoga to improve joint flexibility and manage pain.

Weight and Exercise:

  • Maintain a healthy weight with regular low-strain exercises.
  • Eat balanced, nutritious meals to support joint health.

Rest and Recovery:

  • Get enough sleep to allow muscles and joints to rest.
  • Proper rest helps reduce swelling and inflammation.

Stress Management:

  • Reduce stress through meditation, reading, or listening to calming music.
  • Relaxing activities like warm baths can ease body discomfort.

Therapies:

  • Consider massage, physiotherapy, or acupuncture for added relief.

Diet Choices:

  • Include antioxidant-rich foods like berries, spinach, and beans.
  • Eat foods with flavonoids such as broccoli, grapes, and green tea.

Habits:

  • Avoid smoking and alcohol to protect joint and muscle health.

Habit Forming

No

Therapeutic Class

ANALGESICS

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Proxym-MR Tablet as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding; your doctor will decide whether Proxym-MR Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Proxym-MR Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.

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Children

Unsafe

Proxym-MR Tablet is not recommended for children, as its safety and effectiveness have not been established.

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Heart

Unsafe

This medicine is not recommended for cardiac patients due to its adverse effects. However, if prescribed, extreme caution should be exercised.

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Geriatrics

Caution

Proxym-MR Tablet should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Proxym-MR Tablet .

FAQs

Proxym-MR Tablet is used to treat osteoarthritis, rheumatoid arthritis, pain, and muscle spasms.

Proxym-MR Tablet is a combination of two drugs: Etodolac and Thiocolchicoside. Etodolac blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical, and prostaglandins. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Thiocolchicoside works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improve muscle movements, thereby helping relieve pain due to muscle spasms.

Proxym-MR Tablet is used to reduce and relieve pain and inflammation associated with osteoarthritis and rheumatoid arthritis. Arthritis is tenderness and swelling in the joints.

Avoid taking Proxym-MR Tablet if you have stomach ulcers, bleeding problems, or heart problems. Talk to your doctor regarding your concerns; he/she may prescribe alternate medicine.

Diarrhoea might be a side-effect of Proxym-MR Tablet . Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in your stools (tarry stools) or severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Proxym-MR Tablet contains etodolac, which might make the skin sensitive to sunlight and may result in sunburn. Avoid exposure to sunlight and artificial UV rays such as tanning beds and sunlamps while taking Proxym-MR Tablet . Whenever you step out of the home, try to apply sunscreen.

Proxym-MR Tablet may increase the risk of a fatal heart attack or stroke. If you have any recent heart bypass surgery, do not use Proxym-MR Tablet . Talk to your doctor before taking Proxym-MR Tablet if you have heart problems.

Yes, Proxym-MR Tablet is a painkiller. It is a combination medication that helps relieve pain, inflammation, and muscle spasms.

No, Proxym-MR Tablet and Etodolac are not the same. Proxym-MR Tablet is a combination medication containing Etodolac and Thiocolchicoside, whereas Etodolac is a single ingredient. Both are pain relievers, but they differ in their mechanisms of action. Proxym-MR Tablet has a combined effect; Etodolac has a single mechanism of action.

Store Proxym-MR Tablet by keeping it cool, dry, and out of sunlight. Keep it out of the reach of children. Regularly check the expiration date. When you need to dispose of the medicine, remove the label, place it in a plastic bag, and throw it away in the household trash. Remember, never flush the medicine down the toilet or sink to prevent harm to others and the environment.

Taking higher doses of Proxym-MR Tablet won't make it more effective. Instead, it can increase side effects and adverse health complications. Always follow the recommended dosage and avoid exceeding the dose.

Proxym-MR Tablet should be taken with a glass of water. Do not chew, break, or crush it. Follow your doctor's instructions regarding dose and duration and complete the entire course as prescribed.

If your pain is relieved, do not stop taking Proxym-MR Tablet . It is essential to discuss this with your doctor. Your doctor may consider tapering the dosage of Proxym-MR Tablet or, in some cases, recommend stopping the medication altogether. However, this decision should only be made under the guidance of your doctor, as they will assess your individual situation and determine the best course of action.

Proxym-MR Tablet may cause dizziness in some individuals as a side effect. However, individual responses to medication may vary. If you experience dizziness, rest for some time. This side effect may not require medical attention and will vanish over time. But if your dizziness persists and worsens, please consult a doctor for relief. Make sure to avoid driving or activities that require attention until you are okay.

Proxym-MR Tablet can be an effective treatment option for various conditions, but it's essential to use it responsibly. While generally safe, it's contraindicated in patients with hypersensitivity, active gastrointestinal bleeding or ulceration, severe renal or hepatic impairment, pregnancy, lactation, and children. To minimise risks, caution is advised in patients with gastrointestinal disease, renal or hepatic impairment, hypertension, heart failure, or those taking anticoagulants, antiplatelets, or other NSAIDs. For personalised guidance and to ensure safe treatment, please consult your doctor before taking Proxym-MR Tablet .

Proxym-MR Tablet may cause kidney damage, especially with long-term or high-dose use or in patients with pre-existing kidney disorders, because it contains etoricoxib, which can reduce blood flow to the kidneys and increase the risk of kidney damage. Inform your doctor if you have pre-existing kidney disorders. They will assess your kidney health, prescribe accordingly, and adjust the dose and duration if the benefits outweigh the risks. Do not exceed the recommended dose and duration of Proxym-MR Tablet . Always follow your doctor's instructions carefully.

The common side effects of Proxym-MR Tablet , that may occur in some individuals, include nausea, vomiting, heartburn, stomach pain, loss of appetite, indigestion & sleepiness. However, these symptoms vanish as your body adjusts to the medication. If any of these symptoms worsen, please consult a doctor for relief.

If you forget a dose of Proxym-MR Tablet , take it immediately upon remembering. However, if your next dose is near, skip the missed dose and continue with your regular schedule. Never double-dose to make up for a missed dose, as this may increase side effects.

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - PRO0963

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