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  3. PTD 10mg/20mg Tablet

PTD 10mg/20mg Tablet, Pack of 1 Tablet
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

PTD 10mg/20mg Tablet is used to treat acidity-related conditions, nausea, vomiting, and upper abdominal discomfort. It contains pantoprazole and domperidone, which work by reducing stomach acid production and improving stomach and intestinal motility. In some cases, this medicine may cause side effects like diarrhoea, stomach pain, flatulence (gas), dry mouth, dizziness, and headache. Before starting PTD 10mg/20mg Tablet, let the doctor know if you are pregnant, breastfeeding, taking any other medicines or have pre-existing medical conditions.

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Composition :

DOMPERIDONE-10MG + PANTOPRAZOLE-20MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About PTD 10mg/20mg Tablet

PTD 10mg/20mg Tablet is indicated in the treatment of gastro-oesophageal reflux disease (acid reflux), erosive esophagitis (inflammation of the oesophagus due to acid reflux), and gastric and duodenal ulcers. Additionally, it is also used to relieve symptoms of nausea and vomiting, upper abdominal discomfort, feeling of discomfort, and regurgitation of gastric contents.

PTD 10mg/20mg Tablet contains pantoprazole and domperidone. Pantoprazole works by reducing the amount of acid made by the stomach. Domperidone works by increasing the movements of the stomach and intestines. Together, PTD 10mg/20mg Tablet helps treat acidity-related conditions.

The most common side effects of PTD 10mg/20mg Tablet are diarrhoea, stomach pain, flatulence (gas), dry mouth, dizziness, and headache. Most of these side effects may not require medical attention and resolve over time. However, if the side effects persist or worsen, consult your doctor.

Do not take PTD 10mg/20mg Tablet if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. PTD 10mg/20mg Tablet is not recommended for children below 12 years. Keep the doctor informed about your health condition and medications to prevent any interactions.

Uses of PTD 10mg/20mg Tablet

PTD 10mg/20mg Tablet is used in the treatment of Gastroesophageal reflux disease (GERD), Heartburn due to hyperacidity, Inflammation of the food pipe (esophagitis), and Peptic ulcers.The detailed uses of PTD 10mg/20mg Tablet are as follows:
• Gastroesophageal Reflux Disease (GERD): PTD 10mg/20mg Tablet is commonly used to alleviate GERD symptoms and lower stomach acid production by relieving heartburn and acid reflux.
• Peptic Ulcers: PTD 10mg/20mg Tablet is useful in treating peptic ulcers, assisting in healing and minimising ulcer recurrence by regulating gastric acid output.
• Dyspepsia: PTD 10mg/20mg Tablet is usually given to treat dyspeptic symptoms such as bloating, nausea, and discomfort by improving stomach motility.
• Zollinger-Ellison Syndrome: PTD 10mg/20mg Tablet is used to treat Zollinger-Ellison syndrome, a disorder marked by increased stomach acid production, and it aids in reducing the symptoms and problems associated with the condition.
• Inflammation of the food pipe (esophagitis): PTD 10mg/20mg Tablet is also involved in treating esophagitis and works by blocking the gastric proton pump to relieve symptoms and promote healing.

Directions for Use

  • PTD 10mg/20mg Tablet should be taken 30-60 minutes before a meal to enhance absorption and effectiveness.
  • It is usually taken once daily in the morning or as advised by your doctor. If prescribed twice daily, take the second dose before dinner.
  • Swallow PTD 10mg/20mg Tablet as a whole with a glass of water.
  • Do not crush, chew, open, or break it.

Medicinal Benefits

  • PTD 10mg/20mg Tablet is indicated in the treatment of acidity-related conditions, such as heartburn, gastro-oesophageal reflux disease (acid reflux), erosive esophagitis (inflammation of the oesophagus due to acid reflux), and gastric and duodenal ulcers.
  • It is also used to relieve symptoms such as nausea and vomiting, upper abdominal discomfort, bloating, and regurgitation of gastric contents.
  • PTD 10mg/20mg Tablet contains pantoprazole and domperidone. Pantoprazole is a proton pump inhibitor which works by reducing the amount of acid produced in the stomach. Domperidone is a prokinetic that works by improving the movement of the stomach and intestines.
  • PTD 10mg/20mg Tablet helps manage acidity-related conditions, promotes digestion, and provides relief from associated discomfort.

How PTD 10mg/20mg Tablet Works

PTD 10mg/20mg Tablet contains pantoprazole (proton pump inhibitor) and domperidone (prokinetic). Pantoprazole works by reducing the amount of acid made by the stomach. Domperidone works by increasing the motility of the stomach and intestines. Together, PTD 10mg/20mg Tablet helps treat acidity-related conditions, nausea, vomiting, and abdominal discomfort.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of PTD 10mg/20mg Tablet

Do not take more than the prescribed dose of PTD 10mg/20mg Tablet as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take PTD 10mg/20mg Tablet if you are allergic to any of its components.
  • Inform the doctor if you have kidney, liver or heart problems, osteoporosis, high levels of calcium, blockage in the intestines, prolactinoma (prolactin-releasing pituitary tumour), or any other health condition.
  • Prolonged intake of PTD 10mg/20mg Tablet may increase the risk of cyanocobalamin deficiency, Clostridium difficile-associated Diarrhoea (CDAD), bone fractures, and low magnesium levels. Therefore, take PTD 10mg/20mg Tablet only for the duration advised by your doctor. If you are on long-term treatment, regular monitoring is advised.
  • Consult the doctor if you are pregnant or breastfeeding. PTD 10mg/20mg Tablet is not recommended for children as safety and effectiveness have not been established.
  • Let your doctor know if you are taking any other medicines, including supplements and herbal products, to prevent any interactions.

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical
DomperidoneRitonavir
Severe

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical
How does the drug interact with PTD 10mg/20mg Tablet:
Co-administration of Rilpivirine is taken with PTD 10mg/20mg Tablet, can decrease the absorption and blood levels of Rilpivirine and make the medication less effective.

How to manage the interaction:
Taking PTD 10mg/20mg Tablet with Rilpivirine can lead to an interaction, please consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
DomperidoneRitonavir
Severe
How does the drug interact with PTD 10mg/20mg Tablet:
Coadministration of PTD 10mg/20mg Tablet with Ritonavir can increase the blood levels of PTD 10mg/20mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between PTD 10mg/20mg Tablet and Ritonavir, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneCitalopram
Severe
How does the drug interact with PTD 10mg/20mg Tablet:
Coadministration of PTD 10mg/20mg Tablet with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking PTD 10mg/20mg Tablet and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneKetoconazole
Severe
How does the drug interact with PTD 10mg/20mg Tablet:
Coadministration of PTD 10mg/20mg Tablet with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking PTD 10mg/20mg Tablet and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneMethadone
Severe
How does the drug interact with PTD 10mg/20mg Tablet:
Coadministration of PTD 10mg/20mg Tablet with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking PTD 10mg/20mg Tablet and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with PTD 10mg/20mg Tablet:
Coadministration of PTD 10mg/20mg Tablet with Nefazodone can increase the blood levels of PTD 10mg/20mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between PTD 10mg/20mg Tablet and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneToremifene
Severe
How does the drug interact with PTD 10mg/20mg Tablet:
Coadministration of PTD 10mg/20mg Tablet with Toremifene can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking PTD 10mg/20mg Tablet and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with PTD 10mg/20mg Tablet:
Coadministration of PTD 10mg/20mg Tablet with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking PTD 10mg/20mg Tablet and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneClarithromycin
Severe
How does the drug interact with PTD 10mg/20mg Tablet:
Coadministration of PTD 10mg/20mg Tablet with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between PTD 10mg/20mg Tablet and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
DomperidoneBepridil
Severe
How does the drug interact with PTD 10mg/20mg Tablet:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking PTD 10mg/20mg Tablet and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
  • Before going to sleep, try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows; one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid taking alcohol and smoking cigarettes. Alcohol can raise the level of production of stomach acid, leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), which prevents the backflow of the stomach acid back into the food pipe.
  • Include high fibre-containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal. These foods are full of antioxidants, calcium and vitamin B12 that can help cope with the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help prevent excess stomach acid production. Cranberry juice can be beneficial for peptic ulcers and H pylori infection.
  • Avoid sitting continuously, as it can increase stomach acid production. Take a break of 5 minutes in 1 hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS

PTD 10mg/20mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is best to avoid alcohol while taking medication.

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Pregnancy

Caution

If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine. You should use this medicine only if your doctor considers the benefit for you greater than the potential risk for your unborn child or baby.

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Breast Feeding

Caution

PTD 10mg/20mg Tablet should be used in breastfeeding mothers only if the benefits outweigh the risks.

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Driving

Caution

Drive only if you are physically stable and mentally focussed, If you experience drowsiness after taking PTD 10mg/20mg Tablet you should not drive or operate any machinery or vehicles.

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Liver

Caution

In patients with severe liver impairment, the liver enzymes should be monitored regularly during treatment with pantoprazole, particularly on long-term use

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Kidney

Caution

Inform your doctor before receiving the PTD 10mg/20mg Tablet if you have a kidney impairment/disorder. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

PTD 10mg/20mg Tablet is not recommended for children as safety and effectiveness have not been established.

Have a query?

FAQs

PTD 10mg/20mg Tablet is used to treat Gastroesophageal reflux disease (GERD), Heartburn due to hyperacidity, Inflammation of food pipe (esophagitis), and Peptic ulcer.

Domperidone works by increasing the movement of food through the stomach and the digestive tract more quickly and, in this way, reduces the feeling of bloating, fullness and indigestion. On the other hand, it effectively blocks the action of a vomiting centre (chemoreceptor trigger zone - CTZ) located in your brain, which is responsible for inducing the feeling of nausea and vomiting. Pantoprazole helps in reducing stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall and is responsible for the release of gastric acid, damaging tissues in the food pipe, stomach, and duodenum.

PTD 10mg/20mg Tablet can be safely taken as long as your doctor has prescribed it to you.

Yes, taking PTD 10mg/20mg Tablet for a very long time can cause calcium depletion in the body, leading to weakening of bones. Hence, a calcium and vitamin D supplement is recommended along with PTD 10mg/20mg Tablet to replenish calcium depletion in the body.

Yes. PTD 10mg/20mg Tablet can alter certain medical tests, such as those for neuroendocrine tumours (secretin stimulation test) and urine screening tests for tetrahydrocannabinol (THC). So, before undergoing such diagnostic tests, contact your doctor.

Prolonged intake of PTD 10mg/20mg Tablet may weaken your bones and lower your haemoglobin level. Your doctor may prescribe you Vitamin B12 to enhance haemoglobin and calcium/vitamin D/magnesium supplements for bone health.

A combination of pantoprazole and domperidone is effective and safe.

No, PTD 10mg/20mg Tablet is a prescribed drug with minimal side effects. Only take it if your doctor has recommended it to you for acidity.

PTD 10mg/20mg Tablet is an antacid medicine containing Domperidone (anti-emetic) and Pantoprazole (proton pump inhibitor). It is used to treat acidity-related conditions.

Yes, PTD 10mg/20mg Tablet is safe for use if taken in the dose and duration prescribed by the doctor.

Do not take PTD 10mg/20mg Tablet if you are allergic to any of its components. It should be used with caution in patients with liver or kidney disease.

Dry mouth could be a side-effect of PTD 10mg/20mg Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

PTD 10mg/20mg Tablet may cause diarrhoea as a side effect. Drink enough fluids and eat fibre-rich food if you experience diarrhoea. Consult the doctor if the diarrhoea persists or worsens.

Store PTD 10mg/20mg Tablet at room temperature, in a dry place. Keep out of sight and reach of children.

Foods/drinks that aggravate acidity like fried or spicy food, butter, oil, beverages containing caffeine, citrus fruits and alcohol should be avoided.

Alcohol may not affect PTD 10mg/20mg Tablet. However, it might increase acid production. Therefore, avoid alcohol consumption.

Do not discontinue PTD 10mg/20mg Tablet without consulting your doctor. To treat your condition effectively, keep taking PTD 10mg/20mg Tablet for the prescribed duration.

Country of origin

India
Other Info - PT70473

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 15, 2025 | 12:18 PM IST

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Reference

  1. https://www.krishlarpharma.com/product/kritzol-d/
  2. https://www.zuventus.com/sites/default/files/2024-09/Pansa%20D%20PIL.pdf
  3. https://www.quest.com.np/wp-content/uploads/2024/01/Patient-Information-Leaflet-of-QPDOM.pdf
  4. https://www.ciplamed.com/product-index/pansec-dsr-capsules-0
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