Topdom Tablet 10's
Cachet Pharmaceuticals Ltd
DOMPERIDONE-10MG + PANTOPRAZOLE-20MG
Topdom Tablet 10's is composed of two medicines, namely: Domperidone and Pantoprazole. Domperidone is a prokinetic and anti-nausea agent that helps to treat indigestion and stomach pain. On the other hand, Pantoprazole is a proton pump inhibitor that reduces the excess stomach acid formation by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). Topdom Tablet 10's is a widely used medicine to treat peptic ulcers and gastroesophageal reflux disease (GERD). Topdom Tablet 10's prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn.
Domperidone works by increasing the movement of food through the stomach and the digestive tract more quickly and in this way reduces the feeling of bloating, or fullness and indigestion. On the other hand, it effectively blocks the action of a vomiting centre (chemoreceptor trigger zone - CTZ) located in your brain, that is responsible for inducing the feeling of nausea and vomiting. Pantoprazole helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum.
Topdom Tablet 10's can be prescribed to the adults and children aged 12 years and over. It is better to take Topdom Tablet 10's an hour before a meal. Topdom Tablet 10's should be swallowed whole with a glass of water. Do not chew, crush, or break it. Avoid intake of Topdom Tablet 10's for more than four weeks of duration without consulting the doctor. You can increase the efficacy of Topdom Tablet 10's by taking a small meal or snacks frequently. Try to avoid caffeine-containing beverages (coffee, tea), spicy/deep fried/processed foods, carbonated drinks, acidic foods like citrus fruits/vegetables (tomatoes).
Like all medicines, Topdom Tablet 10's may cause side effects, although not everybody gets them. The most common side effects of Topdom Tablet 10's are diarrhoea, stomach pain, flatulence (gas), dryness in the mouth, dizziness, and headache. Everyone doesn't need to experience the above side effects. In case of any discomfort, speak with your doctor. Prolonged intake of Pantoprazole is associated with a low level of Vitamin B12 and low magnesium. Hence yearly test of Vitamin B12 and magnesium is required if you are taking Topdom Tablet 10's for the long term. Use of Topdom Tablet 10's is contraindicated in people with lupus (autoimmune inflammatory disease).
Gastroesophageal reflux disease (GERD), Heartburn due to hyperacidity, Inflammation of food pipe (esophagitis), Peptic ulcer.
Topdom Tablet 10's plays a vital role in preventing nausea, vomiting, stomach upset, stomach pain, peptic ulcer, and other conditions due to hyperacidity or acid reflux. Pantoprazole prevents the proton pumps gate from producing an excessive amount of stomach acid. While Domperidone stops nausea (feeling sick) and vomiting (being sick) blocking messages between parts of your brain called the chemoreceptor trigger zone (CTZ) and the vomiting centre.
You should avoid taking Topdom Tablet 10's if you are allergic to Topdom Tablet 10's or proton pump inhibitors, have gastric cancer, liver disease, low magnesium level (osteoporosis), low vitamin B12, pregnant or planning for pregnancy, and breastfeeding mothers. Topdom Tablet 10's may interact with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, ampicillin antibiotic, anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines. Prolonged intake of Topdom Tablet 10's may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), Vitamin B12, and magnesium deficiency. Intake of Topdom Tablet 10's may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in mucous or stool) immediately consult the doctor.
Drug-Drug Interactions: Topdom Tablet 10's may interact with a blood thinner (e.g. clopidogrel, warfarin), antifungal (e.g. ketoconazole, voriconazole, itraconazole, posaconazole), anti-HIV drug (e.g. atazanavir, nelfinavir), iron supplements, antibiotic (e.g. ampicillin, rifampicin), heart medicine (e.g. digoxin) and anti-cancer drug (e.g. methotrexate). Let your doctor know if you are taking these medicines.
Drug-Food Interactions: Topdom Tablet 10's interact with St John's wort plant that is used as an anti-depressant. This plant may affect the working of Topdom Tablet 10's. So avoid its intake with Topdom Tablet 10's.
Drug-Disease Interactions: Topdom Tablet 10's should be not given in patients with C. difficile induced colitis, liver disease, bone fractures, low Vitamin B12 (anaemia), low magnesium (hypomagnesemia).
It is best to avoid alcohol while taking medication.
If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine. You should use this medicine only if your doctor considers the benefit for you greater than the potential risk for your unborn child or baby.
The name is not recommended during breast-feeding. However, your doctor may prescribe it for you during breast-feeding if he/she feels that the benefit to you outweighs the risk. You should not take $ name without doctor's advice.
Drive only if you are physically stable and mentally focussed, If you experience drowsiness after taking Topdom Tablet 10's you should not drive or operate any machinery or vehicles.
In patients with severe liver impairment, the liver enzymes should be monitored regularly during treatment with pantoprazole, particularly on long-term use
If u have or had history or evidence of any kidney-related diseases, please consult the doctor before taking the Topdom Tablet 10's.
Topdom Tablet 10's can be given safely to children provided; dose has been prescribed by a child specialist.
This item is Not Returnable.
Expires on or after - Sep-23
Normally a thick layer of mucous protects the stomach against its own acid secretion. But, in long run, it gets eroded by excessive stomach acid production leading to complications like GERD, peptic ulcer, and Zollinger Ellison syndrome. Gastroesophageal reflux disease (GERD) is a gastrointestinal disorder that occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe that causes heartburn. On the other hand, a peptic ulcer is a painful condition followed by the development of sores or ulcers in the stomach lining or duodenum (first part of the small intestine). Zollinger Ellison syndrome is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production leading to peptic ulcers.
Domperidone works by increasing the movement of food through the stomach and the digestive tract more quickly and in this way reduces the feeling of bloating, or fullness and indigestion. On the other hand, it effectively blocks the action of a vomiting centre (chemoreceptor trigger zone - CTZ) located in your brain, which is responsible for inducing the feeling of nausea and vomiting. Pantoprazole helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum.
Topdom Tablet 10's can be safely taken as long as your doctor has prescribed it to you.
Yes, taking Topdom Tablet 10's for a very long time can cause calcium depletion from the body leading to weakening of bones. Hence a calcium and vitamin D supplement is recommended along with Topdom Tablet 10's to replenish calcium depletion in the body.
Yes. Topdom Tablet 10's can alter certain medical tests like neuroendocrine tumours (secretin stimulation test), and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostics test contact your doctor.
Prolonged intake of Topdom Tablet 10's may weaken your bone and lower haemoglobin level. Your doctor may prescribe you Vitamin B12 for enhancing haemoglobin and calcium/vitamin D/magnesium supplements for bone health.
Combination of pantoprazole and domperidone is effective & safe.
No, Topdom Tablet 10's is a prescribed drug with minimal side effects. Only take it if your doctor has recommended it to you for acidity.
Topdom Tablet 10's
Exhibition Road, P.S. Gandhi Maidan, Patna – 800001
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