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compositionComposition:SILDENAFIL-10MG
prescriptionPrescription Medicine
Pulmofree 10 mg Injection 12.5 ml

Pulmofree 10 mg Injection 12.5 ml belongs to the group of medicines called phosphodiesterase-5 (PDE-5) inhibitors. It is mainly used in the treatment of pulmonary arterial hypertension (high blood pressure in the lungs). This medicine contains sildenafil which helps increase the blood supply by relaxing the blood vessels. Common side effects include headache, indigestion, flushing, insomnia, and diarrhoea.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

SILDENAFIL-10MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Pulmofree 10 mg Injection 12.5 ml

Pulmofree 10 mg Injection 12.5 ml is used to treat pulmonary arterial hypertension (high blood pressure in the lungs), to improve the ability to exercise and to slow down clinical worsening.

Pulmofree 10 mg Injection 12.5 ml contains Sildenafil that relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, treats pulmonary arterial hypertension.

In some cases, Pulmofree 10 mg Injection 12.5 ml may cause side effects such as headache, indigestion, flushing, insomnia, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, talk to your doctor if you experience these side effects persistently.

Do not take Pulmofree 10 mg Injection 12.5 ml if you are allergic to any of the components or if you are taking nitrate medicines or riociguat (a drug used to treat pulmonary hypertension). Pulmofree 10 mg Injection 12.5 ml is not recommended for use in children. Consult your doctor if you experience hearing or visual impairment.

Uses of Pulmofree 10 mg Injection 12.5 ml

Pulmofree 10 mg Injection 12.5 ml belongs to a class of medicines called phosphodiesterase type-5 (PDE-5) inhibitors. It is used to treat pulmonary arterial hypertension. The detailed uses of Pulmofree 10 mg Injection 12.5 ml are as follows:

  • Pulmonary arterial hypertension (PAH): Pulmofree 10 mg Injection 12.5 ml is used to lower high blood pressure in the lungs, helping reduce symptoms such as shortness of breath and enhancing overall physical performance.
  • Improves blood flow to the lungs: Pulmofree 10 mg Injection 12.5 ml relaxes blood vessels in the lungs, improving oxygen supply and lowering pulmonary vascular resistance.
  • Reduces heart workload: Pulmofree 10 mg Injection 12.5 ml relaxes blood vessels in the lungs, improving oxygen supply and lowering pulmonary vascular resistance by easing blood flow through the lungs.
  • Alternative to oral therapy: Pulmofree 10 mg Injection 12.5 ml is used when patients with PAH are unable to take medication orally or need immediate intravenous treatment.

Key Benefits

  • Pulmofree 10 mg Injection 12.5 ml belongs to the group of medicines called phosphodiesterase type-5 (PDE-5) inhibitors
  • It is used to treat pulmonary arterial hypertension (high blood pressure in the lungs) to improve exercise tolerance and slow the clinical worsening.
  • Pulmofree 10 mg Injection 12.5 ml relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart.
Side effects of Pulmofree 10 mg Injection 12.5 ml
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Pulmofree 10 mg Injection 12.5 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Pulmofree 10 mg Injection 12.5 ml Works

Pulmofree 10 mg Injection 12.5 ml contains 'Sildenafil' that relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, treats pulmonary arterial hypertension.
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Alcohol

Consult your doctor

It is not known if alcohol affects Pulmofree 10 mg Injection 12.5 ml. Please consult your doctor.

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Pregnancy

Consult your doctor

Consult your doctor if you are pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

It is not known if Pulmofree 10 mg Injection 12.5 ml passes into breastmilk. Consult your doctor if you are breastfeeding. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Pulmofree 10 mg Injection 12.5 ml may cause dizziness; therefore, you are advised to drive and operate machinery only if you are alert.

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Liver

Consult your doctor

Please consult your doctor if you have any concerns regarding the usage of Pulmofree 10 mg Injection 12.5 ml in patients with liver impairment/liver disease.

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Kidney

Consult your doctor

Please consult your doctor if you have any concerns regarding the usage of Pulmofree 10 mg Injection 12.5 ml in patients with kidney disease.

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Children

Unsafe

Pulmofree 10 mg Injection 12.5 ml is not recommended for children as safety and effectiveness have not been established.

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Heart

Caution

Pulmofree 10 mg Injection 12.5 ml should be used with caution in patients with heart problems, as it may lower blood pressure. Please talk to your doctor before receiving Pulmofree 10 mg Injection 12.5 ml.

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Geriatrics

Caution

Pulmofree 10 mg Injection 12.5 ml should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of Pulmofree 10 mg Injection 12.5 ml

Pulmofree 10 mg Injection 12.5 ml is administered by a healthcare professional in a hospital setting. Hence, the chances of overdose are less. Immediately notify your physician if you experience any of the following symptoms: unusual fatigue or weakness, sweating, confusion, dizziness, faintness, or lightheadedness when getting up quickly from a sitting or lying position. Your doctor may initiate necessary treatment if an overdose is suspected.

Diet & Lifestyle Advise

  • Lower your intake of salt. This helps in reducing the risk of developing oedema.
  • Include vegetables, fruits, whole grains, lean meats, poultry, fish, and fat-free/low-fat dairy products in your diet.
  • Avoid canned foods, processed foods, pickled foods, and frozen foods. Instead, consume fresh foods.
  • Limit consumption of caffeine and alcohol, as they can alter blood pressure.
  • Monitor fluid intake to prevent swelling/fluid retention.

Have a query?

How Soon It Starts Working

  • The time required for Pulmofree 10 mg Injection 12.5 ml to start to work: Pulmofree 10 mg Injection 12.5 ml effect can be observed immediately after administration. 
  • The time for which the effects of Pulmofree 10 mg Injection 12.5 ml last: The duration of action for Pulmofree 10 mg Injection 12.5 ml is unknown.

What if you forget to take Pulmofree 10 mg Injection 12.5 ml

As this medicine is administered in a hospital by your healthcare professional, the chances of missing a dose are less. However, if you have any concerns, contact your doctor.

Storage

• Store in a cool and dry place away from sunlight.• Keep Pulmofree 10 mg Injection 12.5 ml out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Pulmofree 10 mg Injection 12.5 ml if you are allergic to any of the components.
  • Also, avoid taking Pulmofree 10 mg Injection 12.5 ml if you are taking medicines called nitrates, which are used to treat angina or chest pain or guanylate cyclase stimulator medicines (medicines used to treat heart failure and PAH).
  • Inform your doctor if you have/had heart problems such as angina, heart attack, irregular heartbeat, or heart failure, blood circulation problems, low blood pressure, eye or ear problems, sickle cell anaemia (an abnormality of red blood cells), multiple myeloma (cancer of bone marrow) or leukaemia (cancer of blood cells), stomach ulcer, bleeding problems, problems with the shape of the penis or Peyronie's disease (a condition that causes painful erections).
  • Inform your doctor if you are pregnant or breastfeeding. 

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Pulmofree 10 mg Injection 12.5 ml may interact with nitrate medicines, guanylate cyclase stimulators (riociguat), protease inhibitors (ritonavir), alpha-blockers, anti-hypertensive medicines (amlodipine), and other PDE-5 inhibitors.

Drug-Food Interactions: Concomitant use of grapefruit and its juice with Pulmofree 10 mg Injection 12.5 ml is not recommended.

Drug-Disease Interactions: Inform your doctor if you have/had heart problems, blood circulation problems, stomach ulcers, bleeding problems, penis deformity or Peyronie's disease (a condition that causes painful erections).

SildenafilNitroprusside
Critical
SildenafilAmyl nitrite
Critical

Drug-Drug Interactions

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SildenafilNitroprusside
Critical
How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Coadministration of Pulmofree 10 mg Injection 12.5 ml with Nitroprusside can increase the risk of developing low blood pressure.

How to manage the interaction:
Taking Pulmofree 10 mg Injection 12.5 ml with Nitroprusside together is generally avoided as it can lead to an interaction, it can be taken only if prescribed by your doctor. If you experience any side effects such as dizziness, lightheadedness, headache, or heart palpitations you should seek immediate medical attention. Do not discontinue any medications without consulting your doctor.
SildenafilAmyl nitrite
Critical
How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Combining Amyl nitrite and Pulmofree 10 mg Injection 12.5 ml can increase the risk or severity of lower blood pressure.

How to manage the interaction:
Taking Amyl nitrite and Pulmofree 10 mg Injection 12.5 ml together is avoided as it can lead to an interaction, it can be taken only when advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilIndinavir
Critical
How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Coadministration of Indinavir and Pulmofree 10 mg Injection 12.5 ml can increase the blood levels and side effects of Pulmofree 10 mg Injection 12.5 ml.

How to manage the interaction:
Taking Indinavir and Pulmofree 10 mg Injection 12.5 ml together is avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilTelaprevir
Critical
How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Combining Telaprevir and Pulmofree 10 mg Injection 12.5 ml can increase the blood levels and effects of Pulmofree 10 mg Injection 12.5 ml.

How to manage the interaction:
Taking Telaprevir and Pulmofree 10 mg Injection 12.5 ml together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilRitonavir
Critical
How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Coadministration of Ritonavir and Pulmofree 10 mg Injection 12.5 ml may significantly increase the blood levels of Pulmofree 10 mg Injection 12.5 ml.

How to manage the interaction:
Taking Pulmofree 10 mg Injection 12.5 ml with Ritonavir together is generally avoided as it can possibly result in an interaction, it can be taken only if your doctor has advised it. If you notice any of these symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact a doctor. Do not discontinue any medications without consulting a doctor.
SildenafilSaquinavir
Critical
How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Coadministration of Saquinavir and Pulmofree 10 mg Injection 12.5 ml can increase the blood levels and side effects of Pulmofree 10 mg Injection 12.5 ml.

How to manage the interaction:
Taking Saquinavir and Pulmofree 10 mg Injection 12.5 ml together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilIsosorbide dinitrate
Critical
How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Coadministration of Isosorbide dinitrate and Pulmofree 10 mg Injection 12.5 ml can increase the risk of low blood pressure.

How to manage the interaction:
Taking Isosorbide dinitrate and Pulmofree 10 mg Injection 12.5 ml together is generally avoided as it can lead to an interaction, it can be taken only if advised by your doctor. However, if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity) contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilDarunavir
Critical
How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Combining Darunavir and Pulmofree 10 mg Injection 12.5 ml can increase the blood levels and effects of Pulmofree 10 mg Injection 12.5 ml.

How to manage the interaction:
Taking Darunavir and Pulmofree 10 mg Injection 12.5 ml together is avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilAmprenavir
Critical
How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Coadministration of Amprenavir and Pulmofree 10 mg Injection 12.5 ml can increase the blood levels and effects of Pulmofree 10 mg Injection 12.5 ml.

How to manage the interaction:
Taking Amprenavir and Pulmofree 10 mg Injection 12.5 ml together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilAtazanavir
Critical
How does the drug interact with Pulmofree 10 mg Injection 12.5 ml:
Combining Atazanavir and Pulmofree 10 mg Injection 12.5 ml can increase the blood levels and side effects of Pulmofree 10 mg Injection 12.5 ml.

How to manage the interaction:
Taking Atazanavir and Pulmofree 10 mg Injection 12.5 ml together is avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Therapeutic Class

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FAQs

Pulmofree 10 mg Injection 12.5 ml belongs to the group of medicines called phosphodiesterase-5 (PDE-5) inhibitors used to treat pulmonary arterial hypertension (high blood pressure in the lungs), to improve the ability to exercise and to slow down clinical worsening.

Pulmofree 10 mg Injection 12.5 ml relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, treats pulmonary arterial hypertension.

Diarrhoea might be a side effect of Pulmofree 10 mg Injection 12.5 ml. Eat non-spicy food and drink fluids if you experience diarrhoea. Consult your doctor if the condition persists or worsens.

Do not to take Pulmofree 10 mg Injection 12.5 ml with nitrates. Taking Pulmofree 10 mg Injection 12.5 ml with medicines used to treat angina/chest pain such as nitrates/nitroglycerin may cause severe lowering of blood pressure. Consult your doctor if you have a history of heart attack/stroke.

Pulmofree 10 mg Injection 12.5 ml has vasodilation properties which may cause low blood pressure (hypotension). Therefore, inform your doctor if you have resting hypotension, fluid depletion, autonomic dysfunction (dysfunction of the nerves), or severe left ventricular outflow obstruction.

When taken along with vitamin K antagonists, Pulmofree 10 mg Injection 12.5 ml might increase the risk of bleeding. Consult your doctor if you are taking any vitamin K antagonists.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

401, Lsc, C-Block, Mohan Place Saraswati Vihar Delhi Dl 110034 In.
Other Info - PUL0138

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