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compositionComposition:PANTOPRAZOLE-40MG
prescription
Prescription Medicine
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Purfact 40mg Capsule is used to treat gastroesophageal reflux disease (GERD), stomach ulcer, Zollinger Ellison syndrome (overproduction of acid due to pancreatic tumour), duodenal ulcer, gastric ulcer and Crohn's Disease-associated Ulcers. It contains Pantoprazole, which reduces the amount of acid your stomach makes. It prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn. It may cause common side effects like headache, diarrhoea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Praneetha Akunuri , M.Pharmacy
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More about the Product

Composition :

PANTOPRAZOLE-40MG

Manufacturer/Marketer :

Alive Pharmaceutical Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Purfact 40mg Capsule

Purfact 40mg Capsule belongs to the class of drugs known as Proton pump inhibitor, which reduces the amount of acid your stomach makes. It treats gastroesophageal reflux disease (GERD), stomach ulcers, Zollinger-Ellison syndrome (overproduction of acid due to a pancreatic tumour), duodenal ulcers, gastric ulcers, and Crohn’s disease-associated ulcers.

Purfact 40mg Capsule helps reduce stomach acid by blocking the action of an enzyme (H+/K+ ATPase, also known as the gastric proton pump), thus prevents the release of stomach acid and relieving symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

Not everyone who is taking Purfact 40mg Capsule will get these side effects. Purfact 40mg Capsule may have common side effects, such as headache, diarrhoea, nausea, abdominal pain, vomiting, dizziness, and joint pain. These side effects are temporary and may resolve on their own over time. However, if these side effects persist, don't hesitate to contact your doctor.

Take Purfact 40mg Capsule as advised. Your physician will decide the dosage based on your medical condition. You should take Purfact 40mg Capsule 30 minutes before food. It is recommended not to exceed the recommended dose of Purfact 40mg Capsule. Do not chew, crush, or break the medicine.

Inform your physician if you are allergic to Purfact 40mg Capsule. Tell your doctor if you have stomach or intestinal cancer, liver problems, are allergic to Purfact 40mg Capsule or will have an endoscopy in the future. Prolonged intake of Purfact 40mg Capsule may cause a deficiency of Vitamin B12 and low levels of calcium, magnesium and Vitamin D, leading to osteoporosis. Purfact 40mg Capsule is not recommended for children below 5 years of age. Consult the doctor if you are pregnant or breastfeeding.

Uses of Purfact 40mg Capsule

Purfact 40mg Capsule is used to treat peptic ulcers, heartburn, and hyperacidity. The following are the specific applications of Purfact 40mg Capsule:

  • Gastric reflux disease (GERD): Purfact 40mg Capsule is frequently used to treat GERD by decreasing the production of stomach acid, which lessens the symptoms of acid reflux and heartburn.
  • Erosive Esophagitis: This medication efficiently promotes healing and symptom relief for this ailment, which is brought on by inflammation and damage to the oesophagus as a result of acid reflux.
  • Peptic Ulcers: By lowering stomach acid, Purfact 40mg Capsule can be used to treat peptic ulcers and promote the healing of the affected areas.
  • Zollinger-Ellison Syndrome: This uncommon ailment results in an overabundance of stomach acid. Purfact 40mg Capsule considerably lowers acid secretion, which aids with symptom management.

Key Benefits

  • Purfact 40mg Capsule is effective in healing erosive esophagitis (inflammation of the food pipe), heartburn, Zollinger-Ellison syndrome, duodenal ulcers, gastric ulcers, and Crohn’s disease-associated ulcers. 
  • Purfact 40mg Capsule works by irreversibly blocking the proton pump gate, which secretes stomach acid. It can be prescribed to all age groups, including special populations like the elderly, pregnant, lactating mothers, and patients with kidney and liver disease.
  • Purfact 40mg Capsule helps manage acidity-related conditions, promotes digestion, and provides relief from associated discomfort.

Directions for Use

  • Purfact 40mg Capsule should be taken 30-60 minutes before a meal to enhance absorption and effectiveness.
  • It is usually taken once daily in the morning or as advised by your doctor. If prescribed twice daily, take the second dose before dinner.
  • Swallow Purfact 40mg Capsule as a whole with a glass of water.
  • Do not crush, chew, open, or break it.

How Purfact 40mg Capsule Works

Purfact 40mg Capsule contains pantoprazole as an active ingredient. It helps reduce stomach acid by blocking the action of an enzyme (H+/K+ ATPase) that is located in the cells of the stomach wall and is responsible for releasing gastric acid, which can damage tissues in the food pipe, stomach, and duodenum. Purfact 40mg Capsule prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.
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Alcohol

Unsafe

Drinking alcohol with Purfact 40mg Capsule may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid, limit alcohol or contact doctor before intake of Purfact 40mg Capsule.

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Pregnancy

Consult your doctor

Purfact 40mg Capsule is safe for use in pregnant women. However, please consult your physician before taking the medicine. Your doctor will weigh the benefits and potential risks before prescribing it.

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Breast Feeding

Consult your doctor

Purfact 40mg Capsule is safe for use in lactating mothers. However, please consult your physician before taking the medicine. Your doctor will weigh the benefits and potential risks before prescribing it.

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Driving

Caution

In some cases, Purfact 40mg Capsule may cause dizziness, sleepiness, or blur vision. If you observe these symptoms, do not drive or operate heavy machinery until you feel better.

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Liver

Caution

Purfact 40mg Capsule should be taken with caution if you have liver problems.

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Kidney

Consult your doctor

Patients with kidney disease should consult a doctor before taking Purfact 40mg Capsule.

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Children

Caution

Purfact 40mg Capsule is not be prescribed for children under 5 years of age. It is generally prescribed from 5-16 years of children for the treatment of gastroesophageal reflux disease (GERD).

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Heart

Safe if prescribed

Purfact 40mg Capsule can generally be used even if you have heart problems, but only under your doctor’s guidance. Consult your doctor if you have any concerns regarding it.

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Geriatrics

Caution

Purfact 40mg Capsule can be taken by geriatric patients, but with caution and medical supervision.

What if I have taken an overdose of Purfact 40mg Capsule

Do not take more than the prescribed dose of Purfact 40mg Capsule as it may cause gastic irritation, trouble breathing or passing out. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Avoid consuming foods or drinks that trigger acid reflux or heartburn, such as onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes, high-fat foods, and spicy foods.
  • Before going to sleep, raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows; one raised block is fine. This will prevent stomach acid from backing up into your food pipe.
  • Avoid taking alcohol and smoking cigarettes. Alcohol can raise the level of production of stomach acid, leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), preventing the backflow of the stomach acid into the food pipe.
  • Include high-fibre-containing foods, such as berries, cherries, leafy green veggies (like kale and spinach), and black pepper in your meal. These foods are rich in antioxidants, calcium, and vitamin B12, which can help mitigate the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial for peptic ulcers and H. pylori infection.
  • Avoid sitting for long periods, as it can increase stomach acid production. Try to take a 5-minute break every hour by going for a brisk walk or stretching.

health query

Have a query?

How Soon It Starts Working

The time required for Purfact 40mg Capsule to start to work: Purfact 40mg Capsule ideally shows its action within an hour after administration. The time for which the effects of Purfact 40mg Capsule last: The effect of Purfact 40mg Capsule lasts for 24 hours.

What if you forget to take Purfact 40mg Capsule

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and follow your regular dosing schedule. Do not take a double dose to make up for your missed dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Avoid taking Purfact 40mg Capsule if you are allergic to Purfact 40mg Capsule or have any history of gastric cancer, liver disease, low magnesium levels, or low vitamin B1. 
  • Prolonged intake of Purfact 40mg Capsule may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), vitamin B12, and magnesium deficiency. 
  • Purfact 40mg Capsule may interact with blood thinners, antifungals, anti-HIV drugs, iron supplements, and anti-cancer medications. Please inform your doctor if you are taking any of these medications. 
  • Intake of Purfact 40mg Capsule may mask the symptoms of gastric cancer, so if you have any severe stomach pain or blood in stool, immediately consult the doctor.
  • This medicine is not recommended for use in children below 5 years of age. 
  • Although Purfact 40mg Capsule is safe for use during pregnancy or breastfeeding, inform your doctor if you are pregnant or breastfeeding before starting treatment with Purfact 40mg Capsule. 
  • Let your doctor know if you are taking any other medicines, including supplements and herbal products, to prevent any interactions.
  • It is always important to check the expiry date of the medicine. Discard the medicine if it reaches the expiry date.

verifiedApollotooltip

Drug-Drug Interaction: Purfact 40mg Capsule may interact with a blood thinner (clopidogrel, warfarin), antifungal (ketoconazole, voriconazole, itraconazole, posaconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, antibiotic (ampicillin, rifampicin), heart medicine (digoxin) and anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines.

Drug-Food Interaction: Purfact 40mg Capsule interacts with St John's wort plant that is used as an antidepressant. This plant may affect the working of Purfact 40mg Capsule. So avoid its intake with Purfact 40mg Capsule.

Drug-Disease Interaction: Purfact 40mg Capsule should not be given to patients with Clostridium difficile-induced colitis, liver disease, bone fractures, low Vitamin B12 (anaemia), and low magnesium (hypomagnesemia).

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTACIDS]

FAQs

Purfact 40mg Capsule is used to treat Hyperacidity, Heartburn, and Peptic ulcer.
Purfact 40mg Capsule prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.
No. Gas and acidity are two different common discomforts. Acidity is caused when the improper functioning of the valve (sphincter) is located at the junction of the stomach and the food pipe. As a result, stomach acid backs up and enters the upper part of the oesophagus, causing heartburn. On the other hand, gas is a byproduct of digestion, eliminating gases like carbon dioxide, hydrogen, nitrogen, and methane from the body.
Yes. Purfact 40mg Capsule can alter specific medical tests, such as neuroendocrine tumour (secretin stimulation test) and urine screening tests for tetrahydrocannabinol (THC). So, before undergoing such tests, contact your doctor.
Prolonged intake of Purfact 40mg Capsule may weaken your bone and lower your haemoglobin level. Your doctor may prescribe you Vitamin B12 for enhancing haemoglobin and calcium/vitamin D/magnesium supplements for bone health.
No. Purfact 40mg Capsule prevents the excessive production of stomach acid, which can cause acid reflux and heartburn. If blood is present in your stool or mucus, contact your doctor immediately.
Prolonged intake of Purfact 40mg Capsule may lead to atrophic gastritis (inflammation of stomach cells), Vitamin B12 deficiency and weakening of bones or osteoporosis (loss of calcium, magnesium and vitamin D). Your doctor may prescribe calcium, vitamin D or haemoglobin-enhancing medications to cope with long-term side effects.
No. Purfact 40mg Capsule is not prescribed for stomach cancer. Do not take Purfact 40mg Capsule until your doctor has prescribed it to you. Purfact 40mg Capsule is only indicated for the treatment of hyperacidity, acid reflux symptoms (GERD), heartburn and Zollinger-Ellison syndrome.
You should start to feel better in 2-3 days of starting Purfact 40mg Capsule. However, it might take up to 4 weeks for Purfact 40mg Capsule to work properly. Consult a doctor if you don't feel better or if your condition doesn't improve.
A single dose of Purfact 40mg Capsule may not be sufficient. To treat your condition properly, take Purfact 40mg Capsule in the dose and for the duration prescribed by your doctor.
Yes, it is safe to take Purfact 40mg Capsule if your doctor prescribes it. It is a well-tolerated medicine.
Purfact 40mg Capsule is usually prescribed for a short term. However, in some cases, it may be indicated in the long-term management of reflux oesophagitis. If you take Purfact 40mg Capsule on a long-term basis (longer than 1 year), your doctor will advise regular monitoring.
It is best to take Purfact 40mg Capsule 30 minutes to one hour before a meal.
Purfact 40mg Capsule should not be discontinued without a doctor’s consultation. To treat your condition effectively, take Purfact 40mg Capsule for as long as it has been prescribed. Talk to the doctor if you have any concerns.
Purfact 40mg Capsule may cause weight changes as a side effect. Consult the doctor if you notice any weight changes that bother you.
Avoid alcohol consumption as it might make your stomach produce more acid than usual. This can irritate the stomach lining and make your symptoms worse.
Antacids can be taken with Purfact 40mg Capsule if prescribed by the doctor. However, maintain a 2-hour gap between Purfact 40mg Capsule and antacid medicines.
Eat smaller and more frequent meals. Avoid foods that trigger acidity, such as fatty and fried foods, spicy foods, carbonated drinks, and alcohol. Include non-citrus fruits, vegetables, lean meat, oatmeal, whole-grain bread, and rice in your diet. Do not lie down immediately after eating, and avoid vigorous exercise for at least a couple of hours afterwards.
Yes, it is safe to take painkillers along with Purfact 40mg Capsule if advised by the doctor. To prevent stomach upset, painkillers can be taken with or just after a meal.
Purfact 40mg Capsule should be swallowed as a whole with water; do not crush, break or chew it. Purfact 40mg Capsule should be taken 30-60 minutes before meal.
Take the missed dose as soon as you remember, unless it is time for the scheduled dose. Do not take a double dose to make up for the forgotten dose. Take your next regular dose at the usual time.
In some people, Purfact 40mg Capsule may cause side effects such as headaches, diarrhoea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain). Most of these side effects are temporary and usually resolve over time. However, if any side effects persist or worsen, contact your doctor.

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Reference

  1. Drugs.com Clinical Review Team. Pantoprazole Patient Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. National Health Service (NHS). Pantoprazole - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Electronic Medicines Compendium (EMC). Product Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Drugs.com Clinical Review Team. Pantoprazole Granules Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  5. Pantoprazole Pantoprazole. 2000. [Accessed on 28 Mar. 2019]Check here
  6. Drugs and Lactation Database (LactMed®) [Internet]. 2006. [Accessed on 25 Jul. 2023]Check here
  7. Pantoprazole sodium. 2026. [Accessed on 27 Jan. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

Nirmala Apartments,93, Jayprakash Road, Andheri (West),Mumbai - 400 058. India.
Other Info - PU71114
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