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compositionComposition:LEVOFLOXACIN-500MG
prescription
Prescription Medicine
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Qulef IV 500 mg Infusion 100 ml is an antibiotic used in treating bacterial infections such as respiratory tract infections, urinary tract infections, skin and soft tissue infections, prostate infections and serious bacterial infections. It helps stop bacterial growth and effectively clears the infection. This reduces symptoms like fever, pain, and swelling, allowing the body recover faster.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

LEVOFLOXACIN-500MG

Manufacturer/Marketer :

Hetero Healthcare Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Qulef IV 500 mg Infusion 100 ml

Qulef IV 500 mg Infusion 100 ml is a prescription injection used to treat severe, deep-seated bacterial infections in the body. It is typically prescribed for serious lung infections, complex urinary tract issues, and deep skin infections. Its primary medical purpose is to target and destroy the harmful bacteria responsible for your illness, helping your body recover completely.

This medication is injected directly into a vein, and it must be taken on a consistent, scheduled basis to keep a steady level of the medicine in your system. Even if you start feeling better within the first few days, you must complete the entire course of treatment to ensure the infection does not return. While receiving this treatment, staying highly hydrated and resting are essential lifestyle steps that support your recovery.

While using Qulef IV 500 mg Infusion 100 ml, you may experience mild, common side effects such as nausea, headaches, or slight dizziness. However, you should stop the medication and consult your doctor immediately if you experience severe symptoms like sudden tendon pain, numbness in your hands or feet, or severe, watery diarrhoea.

Do not take this if you have had an allergic reaction to similar antibiotics in the past, or if you have a history of tendon swelling or tearing caused by these drugs. It is crucial to talk to your doctor before starting treatment if you have a history of kidney disease, seizures, joint problems, or heart rhythm issues.

This medicine can interact with blood thinners, certain heart medications, and diabetes drugs, so ensure your medical team knows about all other therapies you are using. Let your healthcare provider know if you drink alcohol or smoke, as this can affect your recovery. If you are pregnant, breastfeeding, or an older adult, consult your doctor to discuss specific safety precautions before receiving this injection.

Uses of Qulef IV 500 mg Infusion 100 ml

Your doctor may prescribe Qulef IV 500 mg Infusion 100 ml to help manage the following conditions:

  • Community-acquired and hospital-acquired pneumonia: Qulef IV 500 mg Infusion 100 ml helps clear severe, deep-seated lung infections by destroying the bacteria responsible for the inflammation.
  • Complicated urinary tract and kidney infections: It targets and eliminates stubborn bacterial strains deep within the urinary system and kidneys.
  • Chronic prostate infections: The medicine penetrates prostate tissues to resolve long-standing, painful bacterial infections.
  • Severe skin and soft tissue infections: It stops the spread of aggressive bacteria causing deep skin, wound, or tissue infections.
  • Inhalational anthrax exposure: It serves as a vital preventive and active treatment following exposure to anthrax spores.

Key Benefits

When used as directed as part of your treatment plan, Qulef IV 500 mg Infusion 100 ml may provide the following benefits:

  • Helps treat serious bacterial infections: Helps eliminate susceptible bacteria causing infections in different parts of the body.
  • Helps control the spread of infection: Helps prevent the infection from becoming worse or spreading to other areas of the body.
  • Supports recovery from severe infections: Helps treat serious infections affecting the lungs, urinary tract, kidneys, prostate, skin, and soft tissues when caused by susceptible bacteria.
  • May relieve infection-related symptoms: As the infection improves, symptoms such as fever, pain, swelling, cough, and discomfort may gradually improve.
  • Provides an option when oral treatment is not suitable: May be used when treatment by mouth is not possible or when your doctor considers intravenous treatment more appropriate.
Side effects of Qulef IV 500 mg Infusion 100 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Inflammation of Vagina needs immediate attention and cannot be ignored.
  • Get a physical examination and prevent wearing clothes that can hold heat and moisture.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Follow your doctor's instructions, and rest well with proper medication.
  • Take a balanced diet and get regular screenings to reduce inflammation.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Qulef IV 500 mg Infusion 100 ml will be administered by the doctor.
  • Do not self-administer.

How Qulef IV 500 mg Infusion 100 ml Works

Qulef IV 500 mg Infusion 100 ml contains levofloxacin; it belongs to a class of medications called fluoroquinolone antibiotics (a medicine used to treat bacterial infections). It works by blocking DNA gyrase and topoisomerase IV (enzymes that bacteria need to copy, repair, and divide their genetic material). Without these enzymes, the bacteria cannot grow, multiply, or survive. By killing the bacteria causing the infection, this medicine helps your body's immune system (the body's natural defence against infection) clear the infection. This medicine works only against susceptible bacterial infections. It does not treat viral infections such as the common cold or flu.
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Alcohol

Caution

Alcohol consumption may worsen the side effect of Qulef IV 500 mg Infusion 100 ml like dizziness. It is better to avoid alcohol while you are being treated with Qulef IV 500 mg Infusion 100 ml.

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Pregnancy

Caution

Please consult your doctor before taking Qulef IV 500 mg Infusion 100 ml if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Qulef IV 500 mg Infusion 100 ml is excreted into breast milk. Please consult your doctor before taking Qulef IV 500 mg Infusion 100 ml if you are breastfeeding.

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Driving

Caution

Qulef IV 500 mg Infusion 100 ml may cause side effects like dizziness that could affect your driving ability. Do not drive or operate machinery in such cases. Drive only when you are mentally alert.

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Liver

Caution

Qulef IV 500 mg Infusion 100 ml to be taken with caution if you have a history of liver diseases/conditions.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases or impairment before taking Qulef IV 500 mg Infusion 100 ml.

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Children

Unsafe

Qulef IV 500 mg Infusion 100 ml is not recommended for use in children. If you have any concerns regarding the use of Qulef IV 500 mg Infusion 100 ml, please talk to your doctor.

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Heart

Caution

Qulef IV 500 mg Infusion 100 ml should be used with caution in heart patients, as it may increase the risk of heart rhythm issues like QT prolongation or valve regurgitation. Always consult your doctor to assess risks and explore safer alternatives if needed.

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Geriatrics

Caution

Qulef IV 500 mg Infusion 100 ml can be used in geriatric patients, but older adults are more prone to side effects like tendon rupture, nerve damage, or heart rhythm changes. Doctors usually prescribe it with caution and monitor closely for any adverse reactions.

What if I have taken an overdose of Qulef IV 500 mg Infusion 100 ml

If you suspect an overdose, or if too much medication has been infused too quickly, seek immediate emergency medical attention. Symptoms of an overdose may include extreme dizziness, loss of balance, severe tremors, confusion, or seizures.

Diet & Lifestyle Advise

  • Drink plenty of fluids: Maintain a high intake of water throughout your treatment. Adequate hydration helps your kidneys flush out the medication safely and prevents the formation of crystals in your urine.
  • Avoid direct sunlight: This medicine makes your skin highly sensitive to ultraviolet (UV) light. Wear protective clothing, hats, and a high-SPF sunscreen when outdoors, and avoid tanning beds or sunlamps during treatment.
  • Rest your joints: Avoid strenuous physical activities, heavy lifting, or high-impact sports while receiving this injection and for several weeks afterward to protect your tendons from strain or injury.
  • Support your digestion: Antibiotics can disrupt your gut flora. Consider taking a high-quality probiotic supplement or eating yogurt several hours after your injection to help maintain healthy digestion.
health query

Have a query?

How Soon It Starts Working

  • The time required for Qulef IV 500 mg Infusion 100 ml to start to work: The time required for Qulef IV 500 mg Infusion 100 ml to show its action is unknown.
  • The time for which the effects of Qulef IV 500 mg Infusion 100 ml last: The effect of Qulef IV 500 mg Infusion 100 ml lasts for 12 hours.

What if you forget to take Qulef IV 500 mg Infusion 100 ml

Because this medication is usually injected by a healthcare provider, missed doses are very rare. However, if you are administering this medication at home and miss a scheduled infusion, contact your healthcare provider or clinic immediately for instructions on when to receive your next dose. Do not double the dose to catch up.

Storage

•Store Qulef IV 500 mg Infusion 100 ml injection vials or premixed infusion bags at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Inspect the solution: Before starting your infusion, always check the liquid. It should be clear and pale yellow-green; do not use it if you notice cloudiness, floating particles, or severe discolouration.
  • Rotate infusion sites: If you receive multiple injections, rotate the vein or injection site to minimise localised pain, vein inflammation, and bruising.
  • Monitor blood sugar: If you have diabetes, check your blood glucose levels more frequently, as this class of medicines can cause unexpected drops or spikes in blood sugar.
  • Stop at the first sign of joint pain: Immediately pause any physical activity and call your healthcare provider if you experience sudden joint pain, swelling, or bruising.
  • Ensure a slow infusion rate: Always check that the IV is dripping slowly over the recommended time; infusing this medicine too rapidly can cause a sudden, dangerous drop in blood pressure.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (such as warfarin): May increase the risk of bleeding. Your doctor may need to monitor your blood clotting times more closely.
  • Diabetes medications (including insulin and oral drugs): May lead to erratic blood sugar levels, increasing the risk of severe hypoglycaemia (low blood sugar).
  • Nonsteroidal anti-inflammatory drugs (NSAIDs like ibuprofen): When combined with this injection, the risk of central nervous system stimulation and seizures may increase.
  • Heart rhythm medicines (Class IA or III antiarrhythmics): May increase the risk of developing a dangerous, irregular heart rhythm.
  • Corticosteroids: Significantly elevate the risk of severe tendon inflammation or tendon rupture.
LevofloxacinSotalol
Critical
LevofloxacinAmiodarone
Critical

Drug-Drug Interactions

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LevofloxacinSotalol
Critical
How does the drug interact with Qulef IV 500 mg Infusion 100 ml:
Using sotalol together with Qulef IV 500 mg Infusion 100 ml can increase the risk of an irregular heart rhythm that may be serious. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Qulef IV 500 mg Infusion 100 ml with Sotalol is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. If you experience sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LevofloxacinAmiodarone
Critical
How does the drug interact with Qulef IV 500 mg Infusion 100 ml:
The combination of Amiodarone and Qulef IV 500 mg Infusion 100 ml may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Despite the fact that Amiodarone and Qulef IV 500 mg Infusion 100 ml interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
LevofloxacinDisopyramide
Critical
How does the drug interact with Qulef IV 500 mg Infusion 100 ml:
Combining Qulef IV 500 mg Infusion 100 ml with Disopyramide can increase the risk of irregular heart rhythm .

How to manage the interaction:
Taking Qulef IV 500 mg Infusion 100 ml with Disopyramide is not recommended, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
LevofloxacinZiprasidone
Critical
How does the drug interact with Qulef IV 500 mg Infusion 100 ml:
Taking Qulef IV 500 mg Infusion 100 ml with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Qulef IV 500 mg Infusion 100 ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
LevofloxacinCitalopram
Severe
How does the drug interact with Qulef IV 500 mg Infusion 100 ml:
Taking Qulef IV 500 mg Infusion 100 ml with citalopram increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Concomitant administration of Qulef IV 500 mg Infusion 100 ml with citalopram can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without consulting a doctor.
LevofloxacinHydrocortisone
Severe
How does the drug interact with Qulef IV 500 mg Infusion 100 ml:
Coadministration of Qulef IV 500 mg Infusion 100 ml and Hydrocortisone can induce tendinitis (inflammation of the thick fibrous cords that attach muscle to bone. These cords are called tendons) and tendon rupture.

How to manage the interaction:
Concomitant administration of Qulef IV 500 mg Infusion 100 ml with hydrocortisone can result in an interaction, it can be taken if a doctor has advised it. If you experience pain, swelling, or inflammation in a tendon location such as the back of the ankle, shoulder, biceps, hand, or thumb, call a doctor immediately. You should refrain from exercising or using the afflicted region.
LevofloxacinBempedoic acid
Severe
How does the drug interact with Qulef IV 500 mg Infusion 100 ml:
Co-administration of Qulef IV 500 mg Infusion 100 ml and Bempedoic acid can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bempedoic acid can be taken with Qulef IV 500 mg Infusion 100 ml if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints, consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
LevofloxacinTolazamide
Severe
How does the drug interact with Qulef IV 500 mg Infusion 100 ml:
Coadministration of Qulef IV 500 mg Infusion 100 ml and Tolazamide can affect blood glucose levels - Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose).

How to manage the interaction:
Although taking Qulef IV 500 mg Infusion 100 ml and Tolazamide together can cause an interaction, it can be taken if a doctor has suggested it. If you experience Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat and Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. contact a doctor right away. Do not stop using any medications without talking to a doctor.
LevofloxacinOsimertinib
Severe
How does the drug interact with Qulef IV 500 mg Infusion 100 ml:
Taking Qulef IV 500 mg Infusion 100 ml with Osimertinib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although concomitant administration of Qulef IV 500 mg Infusion 100 ml with Osimertinib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without consulting a doctor.
LevofloxacinMetrizamide
Severe
How does the drug interact with Qulef IV 500 mg Infusion 100 ml:
Coadministration of Qulef IV 500 mg Infusion 100 ml and metrizamide can cause seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Taking Qulef IV 500 mg Infusion 100 ml with Metrizamide together can result in an interaction, but it can be taken if a doctor has advised it. If you have seizures or a head injury, it's important to contact a doctor right away. Don't hesitate to reach out if you experience any of these symptoms. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Qulef IV 500 mg Infusion 100 ml when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Qulef IV 500 mg Infusion 100 ml is an antibiotic used in treating bacterial infections such as respiratory tract infections, urinary tract infections, skin and soft tissue infections, prostate infections and serious bacterial infections.
Qulef IV 500 mg Infusion 100 ml is an antibiotic used to treat bacterial infections. It works by inhibiting bacterial protein synthesis, which retards bacterial growth.
Qulef IV 500 mg Infusion 100 ml should be used with proper caution and doctor consultation if you have any allergic reactions to medicines, liver or kidney diseases, hypokalaemia, diabetes, joint or tendon problems (tendonitis, bursitis), mood disorders (depression), myasthenia gravis (muscle weakness), peripheral neuropathy (nerve damage), fits, aneurysm (weakening of an artery), blockage of the aorta or other blood vessels, high blood pressure, and connective tissue disorders like Marfan syndrome and Ehlers-Danlos syndrome.
Qulef IV 500 mg Infusion 100 ml may cause hypoglycemia (low blood sugar levels) or hyperglycemia (high blood sugar levels). Inform your doctor if you have diabetes, and monitor your blood sugar levels regularly if prescribed.
Qulef IV 500 mg Infusion 100 ml can affect the live vaccines, like the typhoid vaccine, and decrease their effectiveness. Please consult a doctor before you start Qulef IV 500 mg Infusion 100 ml if you are undergoing any vaccinations.
Antacids and multivitamins with minerals can decrease the efficacy of Qulef IV 500 mg Infusion 100 ml. Hence, it is recommended to take Qulef IV 500 mg Infusion 100 ml 2 to 4 hours before or 4 to 6 hours after taking magnesium/aluminium antacids, sucralfate, zinc or iron preparations, and multivitamins with minerals.
Diarrhoea can be a side-effect of Qulef IV 500 mg Infusion 100 ml. Clostridium difficile-associated diarrhoea (CDAD) has also been reported during antibiotic use, such as Qulef IV 500 mg Infusion 100 ml. Therefore, when the patient has diarrhoea, an examination is advised to rule out CDAD following Qulef IV 500 mg Infusion 100 ml therapy.
This medicine is injected slowly into a vein as an intravenous (IV) infusion by a trained healthcare professional, typically over 60 to 90 minutes. Talk to your doctor if you have questions about your administration schedule.
This medication is generally not recommended during pregnancy or breastfeeding unless the medical benefit clearly outweighs the potential risks to the baby. Talk to your doctor to discuss safer treatment alternatives.
This medicine makes your skin highly sensitive to ultraviolet light, which can lead to severe sunburns, blistering, or rashes with very brief sun exposure. Talk to your doctor if you experience a skin reaction.
Yes, this class of antibiotics is clinically recognised to increase the risk of tendonitis and tendon rupture, particularly in the Achilles tendon. Talk to your doctor immediately if you experience sudden joint or tendon pain.
Severe, watery, or bloody diarrhoea can be a sign of a serious secondary gut infection. Avoid taking over-the-counter anti-diarrhoea medicines, as they can make the condition worse. Talk to your doctor right away.
It is highly recommended to avoid alcohol, as it can worsen side effects like dizziness and nausea, and can slow down your body's natural healing process. Talk to your doctor or pharmacist for personalised advice.
If you miss a scheduled clinic appointment or miss a dose during home administration, contact your healthcare provider immediately to reschedule. Do not attempt to double the dose to catch up. Talk to your doctor for a specific catch-up plan.

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Country of origin

India

Manufacturer/Marketer address

Sy.no: 80-84, Melange Towers, Patrika Nagar, Madhapur, Hyderabad, Telangana - 500 081
Other Info - QUL0025
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