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  3. Raciwel 500 Injection 10 ml

Raciwel 500 Injection 10 ml, Pack of 1 INJECTION
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Composition :

FLUOROURACIL-500MG

Manufacturer/Marketer :

Getwell Life Sciences India Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Raciwel 500 Injection

Raciwel 500 Injection belongs to a group of anti-cancer medicines called 'antimetabolites' used to treat breast, colon, rectum, pancreatic and stomach/gastric cancer. Cancer is a disease in which cells divide uncontrollably. Cancer can be localized (benign) or spread to the whole body (metastasized). 

Raciwel 500 Injection contains 'Fluorouracil' that works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells. This prevents the cancer cells from multiplying and growing and eventually kills them.

In some cases, Raciwel 500 Injection may cause nausea, vomiting, weakness, loss of appetite, increased risk of infection, hair loss, diarrhoea, decreased blood cells, and mouth ulcers. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have a metabolic disorder called DPD (dihydropyrimidine dehydrogenase) deficiency, heart problems, bone marrow depression, kidney disease, liver disease, or if you are on treatment with chemotherapy or radiation. Avoid taking Raciwel 500 Injection if you are pregnant or breastfeeding. Both women and men on treatment with Raciwel 500 Injection should use birth control to avoid pregnancy. 

Directions for Use

• Follow your doctor's instructions on the dosage and timing of Raciwel 500 Injection to ensure safe and effective use.• Raciwel 500 Injection will be administered by a doctor or nurse in a hospital.• Do not self-administer it.

Medicinal Benefits

Raciwel 500 Injection belongs to a group of anti-cancer medicines called 'antimetabolites' used to treat breast, colon, rectum, pancreatic and stomach/gastric cancer. Raciwel 500 Injection contains 'Fluorouracil' that works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells. This prevents the cancer cells from multiplying and growing and eventually kills them.

How Raciwel 500 Injection Works

Raciwel 500 Injection contains 'Fluorouracil' that works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells. This prevents the cancer cells from multiplying and growing and eventually kills them.

Storage

Store in a cool and dry place away from sunlight
Side effects of Raciwel 500 Injection 10 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • If you experience symptoms such as mouth ulcers, redness, difficulty in swallowing or talking, abdominal pain, and painful bowel movements as a drug side effect, consult your doctor as they may adjust the dose if necessary or prescribe alternative medication.
  • Practice good hygiene, such as washing your hands regularly, to prevent infection.
  • Drink plenty of water to keep your mucous membranes hydrated and promote healing.
  • Avoid spicy or acidic foods, which can irritate the mucous membranes and exacerbate inflammation.
  • Increase your intake of omega-3 fatty acids, found in fatty fish, nuts, and seeds, to reduce inflammation.
  • Follow a soft food diet to reduce discomfort and promote healing.
  • Eat well-cooked food to minimize infection risk.
  • Practice good hand hygiene to prevent infections.
  • Avoid crowds and people with illnesses to reduce exposure.
  • Wear a mask when necessary to lower infection risk.
  • Rest adequately to support your body's healing process.
  • Stay hydrated by drinking plenty of water.
  • Regularly monitor blood cell counts for changes.
  • Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
  • Consult your doctor right away if concerning symptoms arise.
  • Follow your doctor's guidance on managing myelosuppression and infection prevention.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.

What if I have taken an overdose of Raciwel 500 Injection

Since Raciwel 500 Injection is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

Inform your doctor if you have any infection, a metabolic disorder called DPD (dihydropyrimidine dehydrogenase) deficiency, heart problems, bone marrow depression, kidney disease, liver disease, or if you are on treatment with chemotherapy or radiation. Consult your doctor if you are pregnant because Raciwel 500 Injection can cause harmful effects on the unborn baby. Women and men using Raciwel 500 Injection should use birth control to avoid pregnancy. The use of Raciwel 500 Injection by either parent may result in congenital disabilities. Raciwel 500 Injection should be used with caution in elderly patients. If you have had leukaemia (blood cancer) and are in remission, do not take live vaccines for three months after your last chemotherapy.

Drug-Drug Interactions

verifiedApollotooltip
FluorouracilThalidomide
Severe
FluorouracilWarfarin
Severe

Drug-Drug Interactions

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FluorouracilThalidomide
Severe
How does the drug interact with Raciwel 500 Injection 10 ml:
Taking thalidomide together with Raciwel 500 Injection 10 ml may increase the risk of blood clots and that may lead to serious complications.

How to manage the interaction:
Although taking thalidomide and Raciwel 500 Injection 10 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
FluorouracilWarfarin
Severe
How does the drug interact with Raciwel 500 Injection 10 ml:
Taking Warfarin together with Raciwel 500 Injection 10 ml may increase the risk of bleeding.

How to manage the interaction:
Although taking Warfarin and Raciwel 500 Injection 10 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor immediately if you experience symptoms such as unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not stop using any medications without consulting a doctor.
FluorouracilMitomycin
Severe
How does the drug interact with Raciwel 500 Injection 10 ml:
Taking Raciwel 500 Injection 10 ml with mitomycin has been associated with a condition known as hemolytic uremic syndrome (HUS) and using it with Raciwel 500 Injection 10 ml may increase that risk.

How to manage the interaction:
Although taking Mitomycin and Raciwel 500 Injection 10 ml together can cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without first consulting a doctor.
FluorouracilInfliximab
Severe
How does the drug interact with Raciwel 500 Injection 10 ml:
Using Infliximab together with Raciwel 500 Injection 10 ml can increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Infliximab together with Raciwel 500 Injection 10 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FluorouracilCladribine
Severe
How does the drug interact with Raciwel 500 Injection 10 ml:
Combining Cladribine with Raciwel 500 Injection 10 ml can increase the risk of side effects.

How to manage the interaction:
Taking Cladribine with Raciwel 500 Injection 10 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
FluorouracilClozapine
Severe
How does the drug interact with Raciwel 500 Injection 10 ml:
Co-administration of Raciwel 500 Injection 10 ml with Clozapine can increase the risk of neutropenia (low levels of neutrophils in blood).

How to manage the interaction:
There may be a possibility of interaction between Raciwel 500 Injection 10 ml and Clozapine, but it can be taken if prescribed by a doctor. If you experience any symptoms such as infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain or burning during urination, it is important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
FluorouracilTofacitinib
Severe
How does the drug interact with Raciwel 500 Injection 10 ml:
Using tofacitinib together with Raciwel 500 Injection 10 ml may increase the risk of serious infections.

How to manage the interaction:
Although there is a interaction between tofacitinib and Raciwel 500 Injection 10 ml but can be taken if advised by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
FluorouracilFolic acid
Severe
How does the drug interact with Raciwel 500 Injection 10 ml:
Coadministration of Folic acid and Raciwel 500 Injection 10 ml may increase the effects of Raciwel 500 Injection 10 ml and increase the risk of serious side effects such as bleeding problems, anaemia (lack of blood), infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between Folic acid and Raciwel 500 Injection 10 ml, you can take these medicines together if prescribed by your doctor. However, if you experience diarrhoea, paleness of skin, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body pains, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling in your hands and feet, contact your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.

  • Avoid smoking and alcohol consumption.

  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.

  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

  • Get optimal sleep, and rest well.

Habit Forming

No

Therapeutic Class

ANTIMETABOLITES

Raciwel 500 Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

You are recommended to avoid alcohol consumption while on treatment with Raciwel 500 Injection to prevent unpleasant side effects. Alcohol intake, along with Raciwel 500 Injection, may cause increased drowsiness.

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Pregnancy

Unsafe

It is not recommended for pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Raciwel 500 Injection.

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Breast Feeding

Unsafe

It is not recommended for breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Raciwel 500 Injection. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Safe

Raciwel 500 Injection does not affect your driving ability.

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Liver

Caution

If you have a history of liver disease, inform your doctor before receiving Raciwel 500 Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a history of kidney diseases, inform your doctor before receiving Raciwel 500 Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Children

Unsafe

Raciwel 500 Injection is not recommended for children, as efficacy and safety have not been established.

Have a query?

FAQs

Raciwel 500 Injection is used to treat breast, colon, rectum, pancreatic and stomach/gastric cancer.

Raciwel 500 Injection works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells. This slows the growth of cancer cells and eventually kills them.

Yes, Raciwel 500 Injection affects the hair by making it thin, which further causes hair loss. However, it is not very common. Hair reduction possibly happens due to the estrogen-lowering effect of Raciwel 500 Injection. These effects are not long-lasting and may return after some time. If it matters to you, then consult your doctor for further advice.

Yes, Raciwel 500 Injection may change the results of blood tests and other laboratory tests. Inform the person doing the tests that you are taking Raciwel 500 Injection.

$nanme might affect fertility (ability to have children) in both men and women. You may not be able to become pregnant or father a child after treatment with Raciwel 500 Injection. However, it is essential to talk to your doctor before starting treatment with Raciwel 500 Injection if you think you may want to have a baby in the future.

Country of origin

India

Manufacturer/Marketer address

305, Bakshi House, 40-41, Nehru Place ., New Delhi- 110 017
Other Info - RAC0111

Disclaimer

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 11, 2025 | 4:51 PM IST

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Reference

  1. https://www.drugs.com/mtm/fluorouracil-injection.html
  2. https://www.medicines.org.uk/emc/files/pil.9260.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/012209s040lbl.pdf

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