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  3. Radival 100mg Injection

Radival 100mg Injection, Pack of 1 Injection
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Composition :

SODIUM VALPROATE-100MG/ML

Manufacturer/Marketer :

Psychocare Health Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Radival 100mg Injection

Radival 100mg Injection belongs to the group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, Radival 100mg Injection is also used to treat bipolar disorder. Epilepsy is a central nervous system disorder characterized by a sudden rush of electrical activity in the brain leading to seizures, unusual behavior, and loss of awareness. Bipolar disorder is a mental health disorder associated with episodes of mood swings ranging from manic highs to depressive lows. 
­ 
Radival 100mg Injection contains 'Sodium valproate', which decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Radival 100mg Injection increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder. 
 
Radival 100mg Injection will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side-effects such as sleepiness, dizziness, nausea, headache, and asthenia (weakness). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

If you are of childbearing age, use effective contraception while on treatment with Radival 100mg Injection. Inform your doctor before taking Radival 100mg Injection if you are pregnant or breastfeeding. Do not drive or operate machinery as Radival 100mg Injection may cause sleepiness and dizziness. Avoid consuming alcohol along with Radival 100mg Injection as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Radival 100mg Injection will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Radival 100mg Injection belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy (fits). Radival 100mg Injection decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. Additionally, Radival 100mg Injection is also used to treat bipolar disorder. Radival 100mg Injection increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder. 

How Radival 100mg Injection Works

Radival 100mg Injection contains 'Sodium valproate', which decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Radival 100mg Injection increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder.

Storage

Store in a cool and dry place away from sunlight
Side effects of Radival 100mg Injection
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Radival 100mg Injection

It is unlikely that taking an overdose of Radival 100mg Injection will be harmful to you or your child. However, it might cause transient side effects like diarrhea, nausea, vomiting, and stomach pain. However, it is administered by a health care professional in a hospital. Hence, the chances of overdose are less. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

Do not take Radival 100mg Injection if you are allergic to any of its contents, if you have urea cycle problems, mitochondrial disorders, or hepatic disease/dysfunction. Inform your doctor if you have/had liver problems, porphyria (blood disorder), diabetes, immune system disorder, bleeding problems, systemic lupus erythematosus (a rare skin condition), or kidney problems. Radival 100mg Injection may cause hepatotoxicity (liver damage); consult your doctor if you experience symptoms such as weakness, facial swelling, vomiting, malaise (general discomfort), lethargy (lack of energy or enthusiasm), and anorexia (eating disorder). Radival 100mg Injection may also cause pancreatitis (inflammation of the pancreas); consult your doctor if you experience symptoms such as abdominal pain, vomiting, nausea, and/or anorexia (eating disorder).

Drug-Drug Interactions

verifiedApollotooltip
Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateDoripenem
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Radival 100mg Injection:
Combining Sodium phenylbutyrate and Radival 100mg Injection can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Radival 100mg Injection is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Radival 100mg Injection:
Co-administration of Radival 100mg Injection with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Radival 100mg Injection can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Radival 100mg Injection:
Co-administration of Ketamine and Radival 100mg Injection can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Radival 100mg Injection can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Radival 100mg Injection:
Co-administration of Lithium with Radival 100mg Injection can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Radival 100mg Injection can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Radival 100mg Injection:
Co-administration of Meropenam and Radival 100mg Injection together can reduce the effect of Radival 100mg Injection.

How to manage the interaction:
Co-administration of Meropenam and Radival 100mg Injection can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Radival 100mg Injection:
Using buprenorphine together with Radival 100mg Injection may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Radival 100mg Injection can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Radival 100mg Injection:
Co-administration of Teriflunomide and Radival 100mg Injection can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Radival 100mg Injection can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Radival 100mg Injection:
The combined use of Ertapenem and Radival 100mg Injection can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Radival 100mg Injection can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Radival 100mg Injection:
Co-administration of Leflunomide and Radival 100mg Injection can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Radival 100mg Injection can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Radival 100mg Injection:
Co-administration of Vorinostat with Radival 100mg Injection can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Radival 100mg Injection can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well; get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Have a seizure response plan that helps those around you know what to do.
  • Prepare your living area; small changes may help in reducing the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Radival 100mg Injection as it may cause increased dizziness and sleepiness.

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Pregnancy

Caution

Radival 100mg Injection may cause serious congenital defects and decreased IQ. Therefore, Radival 100mg Injection should be given to pregnant women with epilepsy only if other medicines have failed to control their symptoms or are unacceptable.

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Breast Feeding

Caution

Radival 100mg Injection may pass into breastmilk. Consult your doctor before taking Radival 100mg Injection if you are breastfeeding.

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Driving

Unsafe

Radival 100mg Injection causes dizziness, sleepiness and tiredness. Avoid driving or operating machinery if you experience these symptoms.

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Liver

Unsafe

Radival 100mg Injection may cause hepatotoxicity (liver damage). Therefore it is not recommended in people with hepatic dysfunction. Please inform your doctor if you have a liver impairment or liver problem.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Caution

Radival 100mg Injection can be given to children above 2 years if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight. Radival 100mg Injection should be used with extreme caution in children below 2 years as it might cause hepatotoxicity (liver damage).

Have a query?

FAQs

Radival 100mg Injection belongs to the group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, it is also used to treat bipolar disorder.

Radival 100mg Injection decreases the excessive and abnormal nerve activity in the brain. It balances the brain's chemical messenger and prevents overactivity of the brain, thereby controlling seizures episodes.

Radival 100mg Injection is used to treat bipolar disorder by increasing the amount of a chemical substance called GABA; this helps in blocking the nerve transmission across the brain and provides a calming effect.

Radival 100mg Injection may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a proper diet and exercising regularly.

Radival 100mg Injection may cause hepatotoxicity (liver damage). Consult your doctor if you experience symptoms such as weakness, facial swelling, vomiting, malaise (general discomfort), lethargy (lack of energy or enthusiasm), and anorexia (eating disorder). Serum liver tests before starting Radival 100mg Injection and at regular intervals for at least six months are advised.

Radival 100mg Injection should not be administered to women of child-bearing age unless it is essential to manage her condition. Women of child-bearing age must use effective contraception whilst on treatment with Radival 100mg Injection.

Country of origin

India
Other Info - RA49012

Disclaimer

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 17, 2025 | 10:57 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/020593s026lbl.pdf
  2. https://www.medsafe.govt.nz/Profs/Datasheet/e/EpilimIV.pdfhttp://editor.fresenius-kabi.us/PIs/US-PH-Valproate-Sodium-Inj-FK-45982G-10-2015-PI.pdf
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