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  3. Raltegravir 400mg Tablet

Raltegravir 400mg Tablet, Pack of 1 Tablet
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Raltegravir 400mg Tablet belongs to the class of antiretroviral drugs used in the treatment of HIV infection. This medicine work by inhibiting the replication of HIV by blocking DNA integration into new cells. Common side effects include dizziness, headache, diarrhoea, nausea, vomiting, rashes, and feeling weak.

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Composition :

RALTEGRAVIR-400MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Raltegravir 400mg Tablet

Raltegravir 400mg Tablet belongs to the group of medicines called antiretroviral agents used to treat HIV infection in children and adults. HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses.

Raltegravir 400mg Tablet contains 'Raltegravir' which is a human immunodeficiency virus integrase strand transfer inhibitor (HIV-1 INSTI). It works by inhibiting the replication of HIV by blocking DNA integration into new cells. Thus, Raltegravir 400mg Tablet is effective in controlling the HIV from multiplying and is used in the treatment of HIV.

Take Raltegravir 400mg Tablet in the dose and duration prescribed by the doctor. Raltegravir 400mg Tablet may cause certain side effects such as nausea, tiredness, insomnia, headache and dizziness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.

Inform the doctor if you are allergic to any of the components of Raltegravir 400mg Tablet. Raltegravir 400mg Tablet may cause dizziness, so drive with caution. Raltegravir 400mg Tablet is not recommended during pregnancy or breastfeeding. Avoid alcohol consumption as it might cause increased dizziness. It is important to practise safe sex to avoid transmitting HIV to your partner.

Uses of Raltegravir 400mg Tablet

Raltegravir 400mg Tablet is used in the treatment of HIV infection. The detailed uses of Raltegravir 400mg Tablet are as follows:<br/>• HIV Treatment: Raltegravir 400mg Tablet helps control the virus and boost the immune system when used to treat Human Immunodeficiency Virus (HIV) infections.<br/>• Antiretroviral Therapy: This kit is an essential component of antiretroviral therapy (ART) for people with HIV since it contains a variety of antiretroviral drugs that cooperate to reduce a patient's viral load.<br/>• Stopping HIV Progression: The Raltegravir 400mg Tablet helps stop HIV from developing into Acquired Immunodeficiency Syndrome (AIDS) by keeping a suppressed viral load, which greatly enhances patients' quality of life.<br/>• Enhancing Immune Function: The drugs in this kit help people with HIV maintain and restore their immune systems, which lowers their risk of contracting opportunistic infections.<br/>• Support for Co-infections: Since efficient HIV management is crucial for the treatment of other infectious diseases, Raltegravir 400mg Tablet can be a component of a comprehensive treatment plan for patients who may have co-infections.<br/>

Directions for Use

  • Raltegravir 400mg Tablet can be taken with or without food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Chew the medicine completely before swallowing.
  • Do not crush or break the medicine.

Medicinal Benefits

Raltegravir 400mg Tablet contains 'Raltegravir' which is a human immunodeficiency virus integrase strand transfer inhibitor (HIV-1 INSTI). It works by inhibiting the replication of HIV by blocking DNA integration into new cells. Thus, Raltegravir 400mg Tablet is effective in controlling the HIV from multiplying and is used in the treatment of HIV in adults and children weighing at least 2kgs. Raltegravir 400mg Tablet may decrease the chance of developing AIDS and HIV related illnesses like serious infections or cancer.

How Raltegravir 400mg Tablet Works

Raltegravir 400mg Tablet contains 'Raltegravir' which is a human immunodeficiency virus integrase strand transfer inhibitor (HIV-1 INSTI). It works by inhibiting the replication of HIV by blocking DNA integration into new cells. Thus, Raltegravir 400mg Tablet is effective in controlling the HIV from multiplying and is used in the treatment of HIV.

Storage

• Store in a cool and dry place away from sunlight.• Keep Raltegravir 400mg Tablet out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Raltegravir 400mg Tablet

Do not take more than the prescribed dose of Raltegravir 400mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Inform the doctor if you are allergic to any of the components of Raltegravir 400mg Tablet. Use Raltegravir 400mg Tablet with caution in case of mental health problems, bone problems, liver problems, skin problems, infections and muscle problems. Keep your doctor informed if you have a history of hypertension, diabetes, hepatitis, liver disease, kidney problems or heart disease. Offer a detailed medical and vaccination history. Inform the doctor especially if you are on any antidepressants, antacids, iron supplements, radiotherapy, analgesics, heart medicines, antibiotics, anti-epileptics, antifungals or any other antiretrovirals. Raltegravir 400mg Tablet is not recommended during pregnancy and breastfeeding. Avoid Raltegravir 400mg Tablet use with alcohol. It is important to practise safe sex to avoid transmitting HIV to your partner.

Diet & Lifestyle Advise

  • Practise safe sex to prevent transmitting HIV to your partner. Educate yourself and your partner about pre and post-exposure prophylaxis and ART (anti-retroviral therapy).
  • Meditation and yoga have also proven very effective in helping HIV patients maintain a healthy attitude and body.
  • Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods.
  • Taking a stroll in the garden, or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Raltegravir 400mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

It is not recommended to use alcohol with Raltegravir 400mg Tablet. Please consult your doctor if you have any concerns.

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Pregnancy

Consult your doctor

Limited information available for use of Raltegravir 400mg Tablet in pregnant women. Please consult your doctor regarding the risks and benefits for use of Raltegravir 400mg Tablet.

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Breast Feeding

Consult your doctor

Limited information available for use of Raltegravir 400mg Tablet in breastfeeding mothers. Please consult your doctor regarding the risks and benefits for use of Raltegravir 400mg Tablet.

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Driving

Unsafe

Raltegravir 400mg Tablet may cause tiredness and dizziness, which may affect your ability to drive. Do not drive if you experience any side effects after using Raltegravir 400mg Tablet.

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Liver

Caution

Exercise caution before using Raltegravir 400mg Tablet in case of liver disease as it can derange liver enzymes. Please consult your doctor to address any concerns.

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Kidney

Caution

Exercise caution before using Raltegravir 400mg Tablet in case of kidney disease. Please consult your doctor to address any concerns.

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Children

Caution

Raltegravir 400mg Tablet is not recommended for use in children below two years as the safety and effectiveness have not been established. In children above 2 years of age, the paediatrician will decide the dose based on the severity of the condition and the body weight.

Have a query?

FAQs

Raltegravir 400mg Tablet belongs to the group of medicines called antiretroviral agents&amp;nbsp;used to treat HIV infection.

Raltegravir 400mg Tablet works by inhibiting the replication of viral DNA and by preventing it from being integrated in the human body.

Do not stop taking Raltegravir 400mg Tablet without consulting your doctor as it may reduce the effectiveness of anti-HIV therapy. Continue taking Raltegravir 400mg Tablet for as long as your doctor has prescribed it to you to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Raltegravir 400mg Tablet.

Raltegravir 400mg Tablet does not cure HIV infection. Raltegravir 400mg Tablet reduces the activity of HIV in the body and improves the functioning of the immune system. Raltegravir 400mg Tablet may decrease the chance of developing AIDS and HIV related illnesses like serious infections or cancer.

No, Raltegravir 400mg Tablet is not a protease inhibitor. It is a human immunodeficiency virus integrase strand transfer inhibitor (HIV-1 INSTI), which works by blocking the virus from integrating into the DNA of new cells. In contrast, protease inhibitors are a different class of drugs that target the protease enzyme and prevent the virus from maturing correctly, making them non-infectious.

Raltegravir 400mg Tablet may cause side effects in some individuals. Commonly reported side effects include nausea, tiredness, insomnia, headache, and dizziness. These side effects are usually mild and temporary, often subsiding as your body adjusts to the medication. However, if you experience persistent, severe, or worsening side effects, please consult your doctor promptly for proper evaluation and guidance.

It is unknown whether Raltegravir 400mg Tablet is suitable for pregnant and breastfeeidng mother. Please let your doctor know if you are pregnant or breastfeeding mother abefore taking Raltegravir 400mg Tablet to know about the risk and benifits of the medicine.

Country of origin

India
Other Info - RA36996

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:17 PM IST

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Reference

  1. https://Raltegravir Patient Drug Record: NIH (no date) Raltegravir Patient Drug Record | NIH. Available at:
  2. https://clinicalinfo.hiv.gov/en/drugs/raltegravir/patient#dr4 (Accessed: 08 May 2025). (No date) ISENTRESS® 600 mg film-coated tablets raltegravir. Available at:
  3. https://www.medicines.org.uk/emc/files/pil.8436.pdf (Accessed: 08 May 2025).
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